|
US3927193A
(en)
|
1973-05-18 |
1975-12-16 |
Hoffmann La Roche |
Localization of tumors by radiolabelled antibodies
|
|
GB1541435A
(en)
|
1975-02-04 |
1979-02-28 |
Searle & Co |
Immunological materials
|
|
US4036945A
(en)
|
1976-05-03 |
1977-07-19 |
The Massachusetts General Hospital |
Composition and method for determining the size and location of myocardial infarcts
|
|
US4200690A
(en)
|
1976-12-16 |
1980-04-29 |
Millipore Corporation |
Immunoassay with membrane immobilized antibody
|
|
US4444744A
(en)
|
1980-03-03 |
1984-04-24 |
Goldenberg Milton David |
Tumor localization and therapy with labeled antibodies to cell surface antigens
|
|
US4361544A
(en)
|
1980-03-03 |
1982-11-30 |
Goldenberg Milton David |
Tumor localization and therapy with labeled antibodies specific to intracellular tumor-associated markers
|
|
US4331647A
(en)
|
1980-03-03 |
1982-05-25 |
Goldenberg Milton David |
Tumor localization and therapy with labeled antibody fragments specific to tumor-associated markers
|
|
US4348376A
(en)
|
1980-03-03 |
1982-09-07 |
Goldenberg Milton David |
Tumor localization and therapy with labeled anti-CEA antibody
|
|
US5204095A
(en)
|
1980-04-09 |
1993-04-20 |
National Research Development Corporation |
Monoclonal antibodies against hepatitis B virus
|
|
US4359457A
(en)
|
1980-09-30 |
1982-11-16 |
Neville Jr David M |
Anti Thy 1.2 monoclonal antibody-ricin hybrid utilized as a tumor suppressant
|
|
US4554101A
(en)
|
1981-01-09 |
1985-11-19 |
New York Blood Center, Inc. |
Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity
|
|
US4468457A
(en)
|
1981-06-01 |
1984-08-28 |
David M. Goldenberg |
Method for producing a CSAp tryptic peptide and anti-CSAp antibodies
|
|
US4818709A
(en)
|
1983-01-21 |
1989-04-04 |
Primus Frederick J |
CEA-family antigens, Anti-CEA antibodies and CEA immunoassay
|
|
US4916213A
(en)
|
1983-02-22 |
1990-04-10 |
Xoma Corporation |
Ribosomal inhibiting protein-immunoglobulin conjugates with specificity for tumor cell surface antigens, and mixtures thereof
|
|
US4925922A
(en)
|
1983-02-22 |
1990-05-15 |
Xoma Corporation |
Potentiation of cytotoxic conjugates
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US4624846A
(en)
|
1983-07-29 |
1986-11-25 |
Immunomedics, Inc. |
Method for enhancing target specificity of antibody localization and clearance of non-target diagnostic and therapeutic principles
|
|
US5672347A
(en)
|
1984-07-05 |
1997-09-30 |
Genentech, Inc. |
Tumor necrosis factor antagonists and their use
|
|
US4824659A
(en)
|
1985-06-07 |
1989-04-25 |
Immunomedics, Inc. |
Antibody conjugates
|
|
US5776093A
(en)
|
1985-07-05 |
1998-07-07 |
Immunomedics, Inc. |
Method for imaging and treating organs and tissues
|
|
US5525338A
(en)
|
1992-08-21 |
1996-06-11 |
Immunomedics, Inc. |
Detection and therapy of lesions with biotin/avidin conjugates
|
|
US4918163A
(en)
|
1985-09-27 |
1990-04-17 |
Pfizer Inc. |
Monoclonal antibodies specific for lipid-A determinants of gram negative bacteria
|
|
US5618920A
(en)
|
1985-11-01 |
1997-04-08 |
Xoma Corporation |
Modular assembly of antibody genes, antibodies prepared thereby and use
|
|
US4699784A
(en)
|
1986-02-25 |
1987-10-13 |
Center For Molecular Medicine & Immunology |
Tumoricidal methotrexate-antibody conjugate
|
|
US5057313A
(en)
|
1986-02-25 |
1991-10-15 |
The Center For Molecular Medicine And Immunology |
Diagnostic and therapeutic antibody conjugates
|
|
US6861511B1
(en)
|
1986-06-04 |
2005-03-01 |
Bayer Corporation |
Detection and quantification of neu related proteins in the biological fluids of humans
|
|
US4997913A
(en)
|
1986-06-30 |
1991-03-05 |
Oncogen |
pH-sensitive immunoconjugates and methods for their use in tumor therapy
|
|
US4946778A
(en)
|
1987-09-21 |
1990-08-07 |
Genex Corporation |
Single polypeptide chain binding molecules
|
|
US4704692A
(en)
|
1986-09-02 |
1987-11-03 |
Ladner Robert C |
Computer based system and method for determining and displaying possible chemical structures for converting double- or multiple-chain polypeptides to single-chain polypeptides
|
|
US5567610A
(en)
|
1986-09-04 |
1996-10-22 |
Bioinvent International Ab |
Method of producing human monoclonal antibodies and kit therefor
|
|
US6893625B1
(en)
|
1986-10-27 |
2005-05-17 |
Royalty Pharma Finance Trust |
Chimeric antibody with specificity to human B cell surface antigen
|
|
CA1320905C
(en)
|
1986-11-06 |
1993-08-03 |
Joseph M. Cummins |
Treatment of immuno-resistant disease
|
|
US4932412A
(en)
|
1986-12-18 |
1990-06-12 |
Immunomedics, Inc. |
Intraoperative and endoscopic tumor detection and therapy
|
|
IL85035A0
(en)
|
1987-01-08 |
1988-06-30 |
Int Genetic Eng |
Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
|
|
WO1988007553A1
(fr)
|
1987-03-26 |
1988-10-06 |
Teijin Limited |
Procede de preparation d'un complexe d'anticorps
|
|
US5132405A
(en)
|
1987-05-21 |
1992-07-21 |
Creative Biomolecules, Inc. |
Biosynthetic antibody binding sites
|
|
US4981979A
(en)
|
1987-09-10 |
1991-01-01 |
Neorx Corporation |
Immunoconjugates joined by thioether bonds having reduced toxicity and improved selectivity
|
|
US5831034A
(en)
|
1987-11-13 |
1998-11-03 |
Hermann Katinger |
Human monoclonal anti-HIV-I-antibodies
|
|
US6511665B1
(en)
|
1987-11-25 |
2003-01-28 |
Immunex Corporation |
Antibodies to interleukin-1 receptors
|
|
IL89220A
(en)
|
1988-02-11 |
1994-02-27 |
Bristol Myers Squibb Co |
Anthracycline immunoconjugates, their production and pharmaceutical compositions containing them
|
|
US5112954A
(en)
|
1988-02-26 |
1992-05-12 |
Neorx Corporation |
Method of enhancing the effect of cytotoxic agents
|
|
US4861579A
(en)
|
1988-03-17 |
1989-08-29 |
American Cyanamid Company |
Suppression of B-lymphocytes in mammals by administration of anti-B-lymphocyte antibodies
|
|
US5120525A
(en)
|
1988-03-29 |
1992-06-09 |
Immunomedics, Inc. |
Radiolabeled antibody cytotoxic therapy of cancer
|
|
US5541297A
(en)
|
1988-04-01 |
1996-07-30 |
Immunomedics, Inc. |
Therapeutic conjugates of toxins and drugs
|
|
US5612016A
(en)
|
1988-04-01 |
1997-03-18 |
Immunomedics, Inc. |
Conjugates of antibodies and bifunctional ligands
|
|
US5453359A
(en)
|
1988-06-13 |
1995-09-26 |
American Biogenetic Sciences, Inc. |
Immunoassay and kit for in vitro detection of soluble DesAABB fibrin polymers
|
|
US5439665A
(en)
|
1988-07-29 |
1995-08-08 |
Immunomedics |
Detection and treatment of infectious and inflammatory lesions
|
|
US4925648A
(en)
|
1988-07-29 |
1990-05-15 |
Immunomedics, Inc. |
Detection and treatment of infectious and inflammatory lesions
|
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
|
US6362325B1
(en)
|
1988-11-07 |
2002-03-26 |
Advanced Research And Technology Institute, Inc. |
Murine 4-1BB gene
|
|
US6352694B1
(en)
|
1994-06-03 |
2002-03-05 |
Genetics Institute, Inc. |
Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells
|
|
US5571714A
(en)
|
1988-12-22 |
1996-11-05 |
Celtrix Pharmaceuticals, Inc. |
Monoclonal antibodies which bind both transforming growth factors β1 and β2 and methods of use
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
GB8903021D0
(en)
|
1989-02-10 |
1989-03-30 |
Celltech Ltd |
Chemical compounds
|
|
US5134075A
(en)
|
1989-02-17 |
1992-07-28 |
Oncogen Limited Partnership |
Monoclonal antibody to novel antigen associated with human tumors
|
|
US5171665A
(en)
|
1989-04-17 |
1992-12-15 |
Oncogen |
Monoclonal antibody to novel antigen associated with human tumors
|
|
JPH02283294A
(ja)
|
1989-04-24 |
1990-11-20 |
Sumitomo Chem Co Ltd |
ヒトモノクローナル抗体
|
|
US6432402B1
(en)
|
1989-05-25 |
2002-08-13 |
Sloan-Kettering Institute For Cancer Research |
Anti-idiotypic antibody which induces an immune response against a glycosphingolipid and use thereof
|
|
EP0432249B1
(en)
|
1989-06-02 |
1996-09-25 |
The Johns Hopkins University School Of Medicine |
Monoclonal antibodies against leukocyte adhesion receptor beta-chain, methods of producing these antibodies and use therefore
|
|
US5332567A
(en)
|
1989-08-24 |
1994-07-26 |
Immunomedics |
Detection and treatment of infections with immunoconjugates
|
|
DE69030172T2
(de)
|
1990-01-26 |
1997-06-19 |
Immunomedics Inc |
Impfstoffe gegen Krebs und Infektionskrankheiten
|
|
IL97459A0
(en)
|
1990-03-09 |
1992-06-21 |
Hybritech Inc |
Trifunctional antibody-like compounds as a combined diagnostic and therapeutic agent
|
|
WO1991013974A1
(en)
|
1990-03-14 |
1991-09-19 |
The Biomembrane Institute |
Monoclonal antibody and immunoconjugates for the treatment and detection of b cell disorders
|
|
US7041293B1
(en)
|
1990-04-03 |
2006-05-09 |
Genentech, Inc. |
HIV env antibodies
|
|
US5229275A
(en)
|
1990-04-26 |
1993-07-20 |
Akzo N.V. |
In-vitro method for producing antigen-specific human monoclonal antibodies
|
|
US5252296A
(en)
|
1990-05-15 |
1993-10-12 |
Chiron Corporation |
Method and apparatus for biopolymer synthesis
|
|
US5270163A
(en)
|
1990-06-11 |
1993-12-14 |
University Research Corporation |
Methods for identifying nucleic acid ligands
|
|
US5637459A
(en)
|
1990-06-11 |
1997-06-10 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: chimeric selex
|
|
US5496938A
(en)
|
1990-06-11 |
1996-03-05 |
Nexstar Pharmaceuticals, Inc. |
Nucleic acid ligands to HIV-RT and HIV-1 rev
|
|
ATE318832T1
(de)
|
1990-06-11 |
2006-03-15 |
Gilead Sciences Inc |
Verfahren zur vervendung von nukleinsäureliganden
|
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
GB9020075D0
(en)
|
1990-09-14 |
1990-10-24 |
Filler Aaron G |
Contrast agents for magnetic resonance imaging of axonal transport
|
|
US5679640A
(en)
|
1991-02-12 |
1997-10-21 |
Cytel Corporation |
Immunosuppressant peptides
|
|
JP3105629B2
(ja)
|
1991-04-23 |
2000-11-06 |
サングスタット メディカル コーポレイション |
特異的結合ペアのメンバーの細胞活性調節接合体
|
|
US5364612A
(en)
|
1991-05-06 |
1994-11-15 |
Immunomedics, Inc. |
Detection of cardiovascular lesions
|
|
IE922437A1
(en)
|
1991-07-25 |
1993-01-27 |
Idec Pharma Corp |
Recombinant antibodies for human therapy
|
|
US5582981A
(en)
|
1991-08-14 |
1996-12-10 |
Gilead Sciences, Inc. |
Method for identifying an oligonucleotide aptamer specific for a target
|
|
EP0604580A1
(en)
|
1991-09-19 |
1994-07-06 |
Genentech, Inc. |
EXPRESSION IN E. COLI OF ANTIBODY FRAGMENTS HAVING AT LEAST A CYSTEINE PRESENT AS A FREE THIOL, USE FOR THE PRODUCTION OF BIFUNCTIONAL F(ab') 2? ANTIBODIES
|
|
US6764681B2
(en)
|
1991-10-07 |
2004-07-20 |
Biogen, Inc. |
Method of prophylaxis or treatment of antigen presenting cell driven skin conditions using inhibitors of the CD2/LFA-3 interaction
|
|
US5854416A
(en)
|
1991-11-14 |
1998-12-29 |
The United States Of America As Represented By The Department Of Health And Human Services |
Streptococcus pneumoniae 37-KDA surface adhesin a protein and nucleic acids coding therefor
|
|
US5474771A
(en)
|
1991-11-15 |
1995-12-12 |
The Trustees Of Columbia University In The City Of New York |
Murine monoclonal antibody (5c8) recognizes a human glycoprotein on the surface of T-lymphocytes, compositions containing same
|
|
US5622929A
(en)
|
1992-01-23 |
1997-04-22 |
Bristol-Myers Squibb Company |
Thioether conjugates
|
|
WO1993015405A1
(en)
|
1992-01-29 |
1993-08-05 |
Sci-Clone, Inc. |
Carcinoma associated antigen (sk1) monoclonal antibodies against sk1, methods of producing these antibodies and use therfor
|
|
US5965132A
(en)
|
1992-03-05 |
1999-10-12 |
Board Of Regents, The University Of Texas System |
Methods and compositions for targeting the vasculature of solid tumors
|
|
WO1993017694A1
(en)
|
1992-03-09 |
1993-09-16 |
San Diego Regional Cancer Center |
An anti-idiotypic antibody and its use in diagnosis and in therapy in hiv-related disease
|
|
US6129914A
(en)
|
1992-03-27 |
2000-10-10 |
Protein Design Labs, Inc. |
Bispecific antibody effective to treat B-cell lymphoma and cell line
|
|
DE69322860T2
(de)
|
1992-04-03 |
1999-07-01 |
Genentech, Inc., South San Francisco, Calif. |
Antikörper gegen alpha v beta 3 integrin
|
|
US6096289A
(en)
|
1992-05-06 |
2000-08-01 |
Immunomedics, Inc. |
Intraoperative, intravascular, and endoscopic tumor and lesion detection, biopsy and therapy
|
|
WO1993021940A1
(en)
|
1992-05-06 |
1993-11-11 |
Immunomedics, Inc. |
Intraoperative, intravascular and endoscopic tumor and lesion detection and therapy
|
|
AU4231393A
(en)
|
1992-05-08 |
1993-12-13 |
Genentech Inc. |
Antibodies to leukemia inhibitory factor
|
|
US5686072A
(en)
|
1992-06-17 |
1997-11-11 |
Board Of Regents, The University Of Texas |
Epitope-specific monoclonal antibodies and immunotoxins and uses thereof
|
|
US5397703A
(en)
|
1992-07-09 |
1995-03-14 |
Cetus Oncology Corporation |
Method for generation of antibodies to cell surface molecules
|
|
ATE139900T1
(de)
|
1992-11-13 |
1996-07-15 |
Idec Pharma Corp |
Therapeutische verwendung von chimerischen und markierten antikörper gegen menschlichen b lymphozyt beschränkter differenzierung antigen für die behandlung von b-zell-lymphoma
|
|
JPH08507070A
(ja)
|
1993-02-22 |
1996-07-30 |
アルザ・コーポレーション |
活性物質の経口投与のための組成物
|
|
US6214345B1
(en)
|
1993-05-14 |
2001-04-10 |
Bristol-Myers Squibb Co. |
Lysosomal enzyme-cleavable antitumor drug conjugates
|
|
US6120768A
(en)
|
1993-05-17 |
2000-09-19 |
Immunomedics, Inc. |
Dota-biotin derivatives
|
|
AU683893B2
(en)
|
1993-05-17 |
1997-11-27 |
Immunomedics Inc. |
Improved detection and therapy of lesions with biotin/avidin-metal chelating protein conjugates
|
|
US5484892A
(en)
|
1993-05-21 |
1996-01-16 |
Dana-Farber Cancer Institute, Inc. |
Monoclonal antibodies that block ligand binding to the CD22 receptor in mature B cells
|
|
US5820858A
(en)
|
1993-05-28 |
1998-10-13 |
The Scripps Research Institute |
Methods and compositions for inhibiting CD14 mediated cell activation
|
|
US5565215A
(en)
|
1993-07-23 |
1996-10-15 |
Massachusettes Institute Of Technology |
Biodegradable injectable particles for imaging
|
|
US6084067A
(en)
|
1993-07-26 |
2000-07-04 |
Dana-Farber Cancer Institute |
CTLA4/CD28 ligands and uses therefor
|
|
UA40577C2
(uk)
|
1993-08-02 |
2001-08-15 |
Мерк Патент Гмбх |
Біспецифічна молекула, що використовується для лізису пухлинних клітин, спосіб її одержання, моноклональне антитіло (варіанти), фармацевтичний препарат, фармацевтичний набір (варіанти), спосіб видалення пухлинних клітин
|
|
US5417972A
(en)
|
1993-08-02 |
1995-05-23 |
The Board Of Trustees Of The Leland Stanford Junior University |
Method of killing B-cells in a complement independent and an ADCC independent manner using antibodies which specifically bind CDIM
|
|
WO1995007102A1
(en)
|
1993-09-09 |
1995-03-16 |
Duke University |
A method of promoting cellular function
|
|
WO1995009917A1
(en)
|
1993-10-07 |
1995-04-13 |
The Regents Of The University Of California |
Genetically engineered bispecific tetravalent antibodies
|
|
US5824701A
(en)
|
1993-10-20 |
1998-10-20 |
Enzon, Inc. |
Taxane-based prodrugs
|
|
WO1995014040A1
(en)
|
1993-11-19 |
1995-05-26 |
Baylor College Of Medicine |
Monoclonal antibodies specific for human interleukin-5
|
|
US5492807A
(en)
|
1993-11-19 |
1996-02-20 |
Santi; Daniel V. |
Method of obtaining diagnostic reagents, assays and therapeutics based on clinical manifestations of a disease
|
|
US5443953A
(en)
|
1993-12-08 |
1995-08-22 |
Immunomedics, Inc. |
Preparation and use of immunoconjugates
|
|
US6432404B1
(en)
|
1993-12-23 |
2002-08-13 |
Icos Corporation |
Methods of inhibiting locomotor damage following spinal cord injury with α D-specific antibodies
|
|
US5922572A
(en)
|
1994-01-25 |
1999-07-13 |
Human Genome Sciences, Inc. |
Polynucleotides encoding haemopoietic maturation factor
|
|
US5487892A
(en)
|
1994-02-24 |
1996-01-30 |
American Biogenetic Sciences, Inc. |
Method for treating thrombotic disease using a fibrin specific monoclonal antibody
|
|
US5639725A
(en)
|
1994-04-26 |
1997-06-17 |
Children's Hospital Medical Center Corp. |
Angiostatin protein
|
|
US6074642A
(en)
|
1994-05-02 |
2000-06-13 |
Alexion Pharmaceuticals, Inc. |
Use of antibodies specific to human complement component C5 for the treatment of glomerulonephritis
|
|
US6100389A
(en)
|
1995-04-21 |
2000-08-08 |
Human Genome Sciences, Inc. |
Polynucleotides encoding a human chemotactic protein
|
|
US5798100A
(en)
|
1994-07-06 |
1998-08-25 |
Immunomedics, Inc. |
Multi-stage cascade boosting vaccine
|
|
US6303769B1
(en)
|
1994-07-08 |
2001-10-16 |
Immunex Corporation |
Lerk-5 dna
|
|
US5686578A
(en)
|
1994-08-05 |
1997-11-11 |
Immunomedics, Inc. |
Polyspecific immunoconjugates and antibody composites for targeting the multidrug resistant phenotype
|
|
US8771694B2
(en)
|
1994-08-12 |
2014-07-08 |
Immunomedics, Inc. |
Immunoconjugates and humanized antibodies specific for B-cell lymphoma and leukemia cells
|
|
AU3272695A
(en)
|
1994-08-12 |
1996-03-07 |
Immunomedics Inc. |
Immunoconjugates and humanized antibodies specific for b-cell lymphoma and leukemia cells
|
|
US5587459A
(en)
|
1994-08-19 |
1996-12-24 |
Regents Of The University Of Minnesota |
Immunoconjugates comprising tyrosine kinase inhibitors
|
|
US6174995B1
(en)
|
1994-08-23 |
2001-01-16 |
Haodong Li |
Human chemokines, CKβ4 and CKβ10/MCP-4
|
|
US6458349B1
(en)
|
1995-06-02 |
2002-10-01 |
Human Genome Sciences, Inc. |
Chemokine β-4 polypeptides
|
|
US6709653B1
(en)
|
1994-09-16 |
2004-03-23 |
Human Genome Sciences, Inc. |
Antibodies specific for human inositol monophosphatase H1
|
|
US5874540A
(en)
|
1994-10-05 |
1999-02-23 |
Immunomedics, Inc. |
CDR-grafted type III anti-CEA humanized mouse monoclonal antibodies
|
|
US5750370A
(en)
|
1995-06-06 |
1998-05-12 |
Human Genome Sciences, Inc. |
Nucleic acid encoding human endothlein-bombesin receptor and method of producing the receptor
|
|
US6538121B1
(en)
|
1994-11-01 |
2003-03-25 |
Human Genome Sciences, Inc. |
Interleukin-1 β converting enzyme like apoptosis protease-3 and 4
|
|
US5677136A
(en)
|
1994-11-14 |
1997-10-14 |
Systemix, Inc. |
Methods of obtaining compositions enriched for hematopoietic stem cells, compositions derived therefrom and methods of use thereof
|
|
US6521227B1
(en)
|
1999-11-18 |
2003-02-18 |
Peter L. Hudson |
Polynucleotides encoding prostatic growth factor and process for producing prostatic growth factor polypeptides
|
|
US6537764B1
(en)
|
1995-01-19 |
2003-03-25 |
Children's Medical Center Corporation |
Method of identifying inhibitors of C—C chemokine receptor 3
|
|
US5786204A
(en)
|
1995-01-20 |
1998-07-28 |
Human Genome Sciences, Inc. |
Human prostatic specific reductase
|
|
US6312691B1
(en)
|
1996-01-26 |
2001-11-06 |
Jeffrey L. Browning |
Lymphotoxin-α/β complexes and anti-lympotoxin-β receptor antibodies as anti-tumor agents
|
|
US6949244B1
(en)
|
1995-12-20 |
2005-09-27 |
The Board Of Trustees Of The University Of Kentucky |
Murine monoclonal anti-idiotype antibody 11D10 and methods of use thereof
|
|
US5798554A
(en)
|
1995-02-24 |
1998-08-25 |
Consorzio Per La Ricerca Sulla Microelettronica Nel Mezzogiorno |
MOS-technology power device integrated structure and manufacturing process thereof
|
|
US5783404A
(en)
|
1995-04-13 |
1998-07-21 |
Amgen Inc. |
Methods and compositions for determining HER-2/neu expression using monoclonal antibodies
|
|
ES2178672T3
(es)
|
1995-04-19 |
2003-01-01 |
Polymun Scient Immunbio Forsch |
Anticuerpos monoclonales frente al vih-1 y vacunas hechas a partir de ellos.
|
|
AUPO591797A0
(en)
|
1997-03-27 |
1997-04-24 |
Commonwealth Scientific And Industrial Research Organisation |
High avidity polyvalent and polyspecific reagents
|
|
US5686292A
(en)
|
1995-06-02 |
1997-11-11 |
Genentech, Inc. |
Hepatocyte growth factor receptor antagonist antibodies and uses thereof
|
|
US6605441B1
(en)
|
1995-06-05 |
2003-08-12 |
Human Genome Sciences, Inc. |
Antibodies against fibroblast growth factor 11
|
|
US5773292A
(en)
|
1995-06-05 |
1998-06-30 |
Cornell University |
Antibodies binding portions, and probes recognizing an antigen of prostate epithelial cells but not antigens circulating in the blood
|
|
US5773252A
(en)
|
1995-06-05 |
1998-06-30 |
Human Genome Sciences, Inc. |
Fibroblast growth factor 15
|
|
WO1996040875A1
(en)
|
1995-06-07 |
1996-12-19 |
Novartis Ag |
Methods for obtaining compositions enriched for hematopoietic stem cells and antibodies for use therein
|
|
US5622699A
(en)
|
1995-09-11 |
1997-04-22 |
La Jolla Cancer Research Foundation |
Method of identifying molecules that home to a selected organ in vivo
|
|
US6068829A
(en)
|
1995-09-11 |
2000-05-30 |
The Burnham Institute |
Method of identifying molecules that home to a selected organ in vivo
|
|
US6340459B1
(en)
|
1995-12-01 |
2002-01-22 |
The Trustees Of Columbia University In The City Of New York |
Therapeutic applications for the anti-T-BAM (CD40-L) monoclonal antibody 5C8 in the treatment of reperfusion injury in non-transplant recipients
|
|
US5783186A
(en)
|
1995-12-05 |
1998-07-21 |
Amgen Inc. |
Antibody-induced apoptosis
|
|
US6441025B2
(en)
|
1996-03-12 |
2002-08-27 |
Pg-Txl Company, L.P. |
Water soluble paclitaxel derivatives
|
|
US5945309A
(en)
|
1996-03-19 |
1999-08-31 |
Human Genome Sciences, Inc. |
Cytostatin III nucleic acids encoding
|
|
US6254868B1
(en)
|
1996-03-20 |
2001-07-03 |
Immunomedics, Inc. |
Glycosylated humanized B-cell specific antibodies
|
|
WO1997034636A1
(en)
|
1996-03-20 |
1997-09-25 |
Immunomedics, Inc. |
Humanization of an anti-carcinoembryonic antigen anti-idiotype antibody and use as a tumor vaccine and for targeting applications
|
|
FR2746398B1
(fr)
|
1996-03-21 |
1998-04-30 |
Bio Merieux |
Anticorps specifique de staphylococcus aureaus, et utilisations
|
|
US6174992B1
(en)
|
1997-03-21 |
2001-01-16 |
Human Genome Sciences, Inc. |
Human endometrial specific steroid-binding factor I, II and III
|
|
US6962981B1
(en)
|
1996-03-25 |
2005-11-08 |
Medarex, Inc. |
Monoclonal antibodies specific for the extracellular domain of prostate-specific membrane antigen
|
|
US6004780A
(en)
|
1996-03-26 |
1999-12-21 |
Human Genome Sciences, Inc. |
Growth factor HTTER36
|
|
US6110463A
(en)
|
1996-03-29 |
2000-08-29 |
North Carolina State University |
Anti-Cryptosporidium parvum preparations
|
|
US6066617A
(en)
|
1996-04-03 |
2000-05-23 |
Human Genome Sciences, Inc. |
Human cystatin F
|
|
AU717020B2
(en)
|
1996-05-03 |
2000-03-16 |
Immunomedics Inc. |
Targeted combination immunotherapy of cancer
|
|
US6136311A
(en)
|
1996-05-06 |
2000-10-24 |
Cornell Research Foundation, Inc. |
Treatment and diagnosis of cancer
|
|
US6107090A
(en)
|
1996-05-06 |
2000-08-22 |
Cornell Research Foundation, Inc. |
Treatment and diagnosis of prostate cancer with antibodies to extracellur PSMA domains
|
|
JP2000516594A
(ja)
|
1996-07-26 |
2000-12-12 |
スミスクライン・ビーチャム・コーポレイション |
免疫細胞介在全身性疾患の改良された治療法
|
|
WO1998010055A1
(en)
|
1996-09-03 |
1998-03-12 |
Kaneka Corporation |
Method for inducing immunosuppressive cells and culturing device to be used therefor
|
|
DE19640207A1
(de)
|
1996-09-30 |
1998-04-02 |
Bayer Ag |
Glycokonjugate von modifizierten Camptothecin-Derivaten (A- oder B-Ring-Verknüpfung)
|
|
JP2001502670A
(ja)
|
1996-10-09 |
2001-02-27 |
カンタベリー ヘルス リミテッド |
樹状細胞に特異的な抗体
|
|
US6056973A
(en)
|
1996-10-11 |
2000-05-02 |
Sequus Pharmaceuticals, Inc. |
Therapeutic liposome composition and method of preparation
|
|
ES2191827T3
(es)
|
1996-10-17 |
2003-09-16 |
Immunomedics Inc |
Conjugado de toxina no antigenica y proteina de fusion de un sistema receptor de penetracion intracelular.
|
|
US6653104B2
(en)
|
1996-10-17 |
2003-11-25 |
Immunomedics, Inc. |
Immunotoxins, comprising an internalizing antibody, directed against malignant and normal cells
|
|
US6812327B1
(en)
|
1996-10-25 |
2004-11-02 |
Human Genome Sciences, Inc. |
Neutrokine-alpha polypeptides
|
|
US6528625B1
(en)
|
1996-10-28 |
2003-03-04 |
Millennium Pharmaceuticals, Inc. |
Anti-CCR5 antibodies and kits comprising same
|
|
US6043348A
(en)
|
1996-11-13 |
2000-03-28 |
Lawman; Michael J. P. |
Antibody recognizing a small subset of human hematopoietic cells
|
|
US6455040B1
(en)
|
1997-01-14 |
2002-09-24 |
Human Genome Sciences, Inc. |
Tumor necrosis factor receptor 5
|
|
AU6241698A
(en)
|
1997-01-21 |
1998-08-07 |
Human Genome Sciences, Inc. |
Tace-like and matrilysin-like polypeptides
|
|
US6605699B1
(en)
|
1997-01-21 |
2003-08-12 |
Human Genome Sciences, Inc. |
Galectin-11 polypeptides
|
|
ATE362982T1
(de)
|
1997-01-28 |
2007-06-15 |
Human Genome Sciences Inc |
ßDEATH-DOMAINß-ENTHALTENDER REZEPTOR 4 (DR4), EIN MITGLIED DER TNF-REZEPTOR SUPERFAMILIE, WELCHER AN TRAIL (APO-2L) BINDET
|
|
US7122636B1
(en)
|
1997-02-21 |
2006-10-17 |
Genentech, Inc. |
Antibody fragment-polymer conjugates and uses of same
|
|
AU747898B2
(en)
|
1997-03-03 |
2002-05-30 |
Bristol-Myers Squibb Company |
Monoclonal antibodies to human CD6
|
|
US6919433B2
(en)
|
1997-03-14 |
2005-07-19 |
Human Genome Sciences, Inc. |
Antibodies to protein HPMBQ91
|
|
US6951924B2
(en)
|
1997-03-14 |
2005-10-04 |
Human Genome Sciences, Inc. |
Antibodies against secreted protein HTEBYII
|
|
US6872568B1
(en)
|
1997-03-17 |
2005-03-29 |
Human Genome Sciences, Inc. |
Death domain containing receptor 5 antibodies
|
|
US6183744B1
(en)
|
1997-03-24 |
2001-02-06 |
Immunomedics, Inc. |
Immunotherapy of B-cell malignancies using anti-CD22 antibodies
|
|
US6306393B1
(en)
|
1997-03-24 |
2001-10-23 |
Immunomedics, Inc. |
Immunotherapy of B-cell malignancies using anti-CD22 antibodies
|
|
ATE302217T1
(de)
|
1997-05-02 |
2005-09-15 |
Us Gov Health & Human Serv |
Immuntoxine, die ein onc protein enthalten, gegen bösartige zellen
|
|
US6284474B1
(en)
|
1998-04-23 |
2001-09-04 |
The Regents Of The University Of California |
Detection and diagnosis of conditions associated with lung injury
|
|
US6372217B1
(en)
|
1997-06-03 |
2002-04-16 |
Regents Of The University Of Minnesota |
Methods for the treatment of CD7+ viral infection with TXU-7-PAP
|
|
US6545130B2
(en)
|
1997-06-04 |
2003-04-08 |
Albert Einstein College Of Medicine Of Yeshiva University |
Monoclonal antibodies to mycobacterium tuberculosis and a modified ELISA assay
|
|
US6358508B1
(en)
|
1997-06-11 |
2002-03-19 |
Human Genome Sciences, Inc. |
Antibodies to human tumor necrosis factor receptor TR9
|
|
WO1999002567A2
(en)
|
1997-07-08 |
1999-01-21 |
Board Of Regents, The University Of Texas System |
Compositions and methods for producing homoconjugates of antibodies which induce growth arrest or apoptosis of tumor cells
|
|
US6165440A
(en)
|
1997-07-09 |
2000-12-26 |
Board Of Regents, The University Of Texas System |
Radiation and nanoparticles for enhancement of drug delivery in solid tumors
|
|
WO1999014330A1
(en)
|
1997-09-18 |
1999-03-25 |
Genentech, Inc. |
DcR3 POLYPEPTIDE, A TNFR HOMOLOG
|
|
US6689607B2
(en)
|
1997-10-21 |
2004-02-10 |
Human Genome Sciences, Inc. |
Human tumor, necrosis factor receptor-like proteins TR11, TR11SV1 and TR11SV2
|
|
US6355244B1
(en)
|
1997-11-17 |
2002-03-12 |
University Of Kentucky Research Foundation |
Methods and compositions for the treatment of psoriasis
|
|
US6610833B1
(en)
|
1997-11-24 |
2003-08-26 |
The Institute For Human Genetics And Biochemistry |
Monoclonal human natural antibodies
|
|
US6562618B1
(en)
|
1997-12-25 |
2003-05-13 |
Japan Tobacco, Inc. |
Monoclonal antibody against connective tissue growth factor and medicinal uses thereof
|
|
US6051228A
(en)
|
1998-02-19 |
2000-04-18 |
Bristol-Myers Squibb Co. |
Antibodies against human CD40
|
|
US6956107B2
(en)
|
1998-02-20 |
2005-10-18 |
Tanox, Inc. |
Inhibitors of complement activation
|
|
US6861227B2
(en)
|
1998-03-19 |
2005-03-01 |
Human Genome Sciences, Inc. |
Antibodies to cytokine receptor common gamma chain like
|
|
CA2326389C
(en)
|
1998-04-21 |
2007-01-23 |
Micromet Gesellschaft Fur Biomedizinische Forschung Mbh |
Novel cd19xcd3 specific polypeptides and uses thereof
|
|
US6200765B1
(en)
|
1998-05-04 |
2001-03-13 |
Pacific Northwest Cancer Foundation |
Non-invasive methods to detect prostate cancer
|
|
US6458933B1
(en)
|
1998-05-20 |
2002-10-01 |
Immunomedics, Inc. |
Therapeutic using a bispecific antibody
|
|
ATE480566T1
(de)
|
1998-06-15 |
2010-09-15 |
Quest Pharmatech Inc |
Immuntherapeutische zusammensetzung und verfahren zur behandlung von prostatakrebs
|
|
US7387779B2
(en)
|
1998-06-17 |
2008-06-17 |
Beth Israel Deaconess Medical Center |
Anti-angiogenic proteins and fragments and methods of use thereof
|
|
US7405320B2
(en)
|
1998-06-22 |
2008-07-29 |
Immunomedics, Inc. |
Therapeutic and diagnostic conjugates for use with multispecific antibodies
|
|
US6962702B2
(en)
|
1998-06-22 |
2005-11-08 |
Immunomedics Inc. |
Production and use of novel peptide-based agents for use with bi-specific antibodies
|
|
US7138103B2
(en)
|
1998-06-22 |
2006-11-21 |
Immunomedics, Inc. |
Use of bi-specific antibodies for pre-targeting diagnosis and therapy
|
|
US7387772B1
(en)
|
1999-06-22 |
2008-06-17 |
Immunimedics, Inc. |
Chimeric, human and humanized anti-CSAP monoclonal antibodies
|
|
US6528269B1
(en)
|
1998-06-22 |
2003-03-04 |
Case Western Reserve University |
Immunological agents specific for prion protein (PRP)
|
|
US6312689B1
(en)
|
1998-07-23 |
2001-11-06 |
Millennium Pharmaceuticals, Inc. |
Anti-CCR2 antibodies and methods of use therefor
|
|
AUPP525198A0
(en)
|
1998-08-13 |
1998-09-03 |
Medvet Science Pty. Ltd. |
Monoclonal antibody inhibitor of GM-CSF, IL-3 and IL-5 and other cytokines and uses thereof
|
|
US6572856B1
(en)
|
1998-09-10 |
2003-06-03 |
The University Of Virginia Patent Foundation |
Methods for the prevention and treatment of cancer using anti-C3b(i) antibodies
|
|
US6818749B1
(en)
|
1998-10-31 |
2004-11-16 |
The United States Of America As Represented By The Department Of Health And Human Services |
Variants of humanized anti carcinoma monoclonal antibody cc49
|
|
WO2000026418A1
(en)
|
1998-11-05 |
2000-05-11 |
The Board Of Trustees Of Leland Stanford Junior University |
Human pan-hcv human monoclonal antibodies
|
|
AU1728800A
(en)
|
1998-11-18 |
2000-06-05 |
Genentech Inc. |
Antibody variants with higher binding affinity compared to parent antibodies
|
|
US6201104B1
(en)
|
1998-12-04 |
2001-03-13 |
Entremed, Inc. |
Angiogenesis—inhibiting protein binding peptides and proteins and methods of use
|
|
PT1140175E
(pt)
|
1998-12-21 |
2006-06-30 |
Ludwig Inst Cancer Res |
Anticorpos para o vegf-d truncado e suas utilizacoes
|
|
JP2002533134A
(ja)
|
1998-12-23 |
2002-10-08 |
ヒューマン ジノーム サイエンシーズ， インコーポレイテッド |
ペプチドグリカン認識タンパク質
|
|
US6682736B1
(en)
|
1998-12-23 |
2004-01-27 |
Abgenix, Inc. |
Human monoclonal antibodies to CTLA-4
|
|
US6488930B1
(en)
|
1999-01-15 |
2002-12-03 |
Millennium Pharmaceuticals, Inc. |
Anti-CCR4 antibodies and methods of use therefor
|
|
US6379698B1
(en)
|
1999-04-06 |
2002-04-30 |
Isis Pharmaceuticals, Inc. |
Fusogenic lipids and vesicles
|
|
EP1179541B1
(en)
|
1999-04-28 |
2004-06-16 |
Board Of Regents, The University Of Texas System |
Compositions and methods for cancer treatment by selectively inhibiting VEGF
|
|
IL146005A0
(en)
|
1999-05-07 |
2002-07-25 |
Genentech Inc |
Treatment of autoimmune diseases with antagonists which bind to b cell surface markers
|
|
US8119101B2
(en)
|
1999-05-10 |
2012-02-21 |
The Ohio State University |
Anti-CD74 immunoconjugates and methods of use
|
|
US7534866B2
(en)
|
2005-10-19 |
2009-05-19 |
Ibc Pharmaceuticals, Inc. |
Methods and compositions for generating bioactive assemblies of increased complexity and uses
|
|
US7829064B2
(en)
|
1999-05-10 |
2010-11-09 |
Immunomedics, Inc. |
Anti-CD74 immunoconjugates and methods
|
|
US7666400B2
(en)
|
2005-04-06 |
2010-02-23 |
Ibc Pharmaceuticals, Inc. |
PEGylation by the dock and lock (DNL) technique
|
|
US7527787B2
(en)
|
2005-10-19 |
2009-05-05 |
Ibc Pharmaceuticals, Inc. |
Multivalent immunoglobulin-based bioactive assemblies
|
|
US7550143B2
(en)
|
2005-04-06 |
2009-06-23 |
Ibc Pharmaceuticals, Inc. |
Methods for generating stably linked complexes composed of homodimers, homotetramers or dimers of dimers and uses
|
|
US6946129B1
(en)
|
1999-06-08 |
2005-09-20 |
Seattle Genetics, Inc. |
Recombinant anti-CD40 antibody and uses thereof
|
|
DE60042785D1
(de)
|
1999-06-09 |
2009-10-01 |
Immunomedics Inc |
Immuntherapie von autoimmunerkrankungen durch die verwendung von b-zell spezifischen antikörpern
|
|
DE19926154A1
(de)
|
1999-06-09 |
2000-12-14 |
Ktb Tumorforschungs Gmbh |
Verfahren zur Herstellung einer injizierbaren Arzneimittelzubereitung
|
|
US20020002270A1
(en)
|
1999-06-16 |
2002-01-03 |
Raymond P. Zinkowski |
Purified antigen for alzheimer's disease, and methods of obtaining and using same
|
|
WO2000078813A2
(en)
|
1999-06-18 |
2000-12-28 |
Emory University |
Huntington disease cellular model: stably transfected pc12 cells expressing mutant huntingtin
|
|
US6964854B1
(en)
|
1999-07-13 |
2005-11-15 |
Science & Technology Corporation |
Compositions and methods useful for the diagnosis and treatment of heparin induced thrombocytopenia/thrombosis
|
|
US6693176B1
(en)
|
1999-07-23 |
2004-02-17 |
University Of Massachusetts |
Antitumor antibodies, proteins, and uses thereof
|
|
US6376654B1
(en)
|
1999-08-13 |
2002-04-23 |
Molecular Discoveries, Llc |
Myeloma cell and ovarian cancer cell surface glycoproteins, antibodies thereto, and uses thereof
|
|
US6716966B1
(en)
|
1999-08-18 |
2004-04-06 |
Altarex Corp. |
Therapeutic binding agents against MUC-1 antigen and methods for their use
|
|
AU7089600A
(en)
|
1999-08-30 |
2001-03-26 |
U.S. Army Medical Research Institute Of Infectious Diseases |
Monoclonal antibodies and vaccines against epitopes on the ebola virus glycoprotein
|
|
JP4776843B2
(ja)
|
1999-10-01 |
2011-09-21 |
イムノゲン インコーポレーティッド |
免疫複合体及び化学療法剤を用いる癌治療用組成物及び方法
|
|
US6824780B1
(en)
|
1999-10-29 |
2004-11-30 |
Genentech, Inc. |
Anti-tumor antibody compositions and methods of use
|
|
US20030031670A1
(en)
|
1999-11-08 |
2003-02-13 |
Jack R. Wands |
Diagnosis and treatment of malignant neoplasms
|
|
US6835370B2
(en)
|
1999-11-08 |
2004-12-28 |
Rhode Island Hospital |
Diagnosis and treatment of malignant neoplasms
|
|
US6994852B1
(en)
|
1999-11-12 |
2006-02-07 |
Temple University-Of The Commonwealth System Of Higher Education |
Inhibition of angiogenesis by antibodies against high molecular weight kininogen domain 5
|
|
US6994976B1
(en)
|
1999-11-19 |
2006-02-07 |
Tittle Thomas V |
Tr3-specific binding agents and methods for their use
|
|
US6319675B1
(en)
|
1999-11-24 |
2001-11-20 |
Millennium Pharmaceuticals, Inc. |
Methods for detecting and/or identifying agents which bind and/or modulate function of “bonzo” chemokine receptor
|
|
US6530944B2
(en)
|
2000-02-08 |
2003-03-11 |
Rice University |
Optically-active nanoparticles for use in therapeutic and diagnostic methods
|
|
US6835549B2
(en)
|
2000-02-24 |
2004-12-28 |
University Of Medicine & Dentistry Of New Jersey |
Immunoassay method for the diagnosis of gastric intestinal metaplasia associated with gastric carcinoma
|
|
US6998468B2
(en)
|
2000-03-23 |
2006-02-14 |
Tanox, Inc. |
Anti-C2/C2a inhibitors of complement activation
|
|
CA2408547A1
(en)
|
2000-05-11 |
2001-11-15 |
Altarex Corp. |
Therapeutic method and composition utilizing antigen-antibody complexation and presentation by dendritic cells
|
|
US6965018B2
(en)
|
2000-06-06 |
2005-11-15 |
Bristol-Myers Squibb Company |
Antibodies directed to B7-related polypeptide, BSL-2
|
|
US6939547B2
(en)
|
2000-07-31 |
2005-09-06 |
The United States Of America As Represented By The Department Of Health And Human Services |
Specific binding agents for KSHV vIL-6 that neutralize a biological activity
|
|
US7060802B1
(en)
|
2000-09-18 |
2006-06-13 |
The Trustees Of Columbia University In The City Of New York |
Tumor-associated marker
|
|
DE60141844D1
(de)
|
2000-10-02 |
2010-05-27 |
Oklahoma Med Res Found |
Assay zum schnellen nachweis vom humanen aktivierten protein c und hochspezifischer monoklonaler antikörper dagegen
|
|
ATE449791T1
(de)
|
2000-10-10 |
2009-12-15 |
Genentech Inc |
Inhibierung von c5 komplement-aktivierung für die behandlung und vorbeugung von xeno-transplantat oder akute vaskuläre abstossung
|
|
US20030133972A1
(en)
|
2000-10-11 |
2003-07-17 |
Targesome, Inc. |
Targeted multivalent macromolecules
|
|
US7138496B2
(en)
|
2002-02-08 |
2006-11-21 |
Genetastix Corporation |
Human monoclonal antibodies against human CXCR4
|
|
GB0028361D0
(en)
|
2000-11-21 |
2001-01-03 |
Glaxo Group Ltd |
Method of separating extra chromosomal dna from other cellular components
|
|
NZ527302A
(en)
|
2001-01-05 |
2006-10-27 |
Abgenix Inc |
Antibodies to insulin-like growth factor I receptor
|
|
US6743898B2
(en)
|
2001-03-15 |
2004-06-01 |
Ochsner Clinic Foundation |
Monoclonal antibodies that suppress B cell growth and/or differentiation
|
|
ATE335515T1
(de)
|
2001-03-30 |
2006-09-15 |
Univ Massachusetts |
Morpholinobildgebung und therapie
|
|
US6824778B2
(en)
|
2001-04-23 |
2004-11-30 |
The United States Of America As Represented By The Secretary Of The Army |
Prophylactic and therapeutic monoclonal antibodies
|
|
US20050048512A1
(en)
|
2001-04-26 |
2005-03-03 |
Avidia Research Institute |
Combinatorial libraries of monomer domains
|
|
US20040175756A1
(en)
|
2001-04-26 |
2004-09-09 |
Avidia Research Institute |
Methods for using combinatorial libraries of monomer domains
|
|
JP4369662B2
(ja)
|
2001-04-26 |
2009-11-25 |
アビディア インコーポレイテッド |
単量体ドメインのコンビナトリアルライブラリー
|
|
US20050089932A1
(en)
|
2001-04-26 |
2005-04-28 |
Avidia Research Institute |
Novel proteins with targeted binding
|
|
US20050053973A1
(en)
|
2001-04-26 |
2005-03-10 |
Avidia Research Institute |
Novel proteins with targeted binding
|
|
WO2002094854A2
(en)
|
2001-05-21 |
2002-11-28 |
The Brigham And Women's Hospital, Inc. |
P.aeruginosa mucoid exopolysaccharide specific binding peptides
|
|
NZ513418A
(en)
|
2001-08-07 |
2004-04-30 |
Univ Massey |
Vaccine comprising proteins from mycobacterium paratuberculosis
|
|
US7049060B2
(en)
|
2001-11-05 |
2006-05-23 |
Ortho-Clinical Diagnostics, Inc. |
HCV anti-core monoclonal antibodies
|
|
US6716821B2
(en)
|
2001-12-21 |
2004-04-06 |
Immunogen Inc. |
Cytotoxic agents bearing a reactive polyethylene glycol moiety, cytotoxic conjugates comprising polyethylene glycol linking groups, and methods of making and using the same
|
|
SE0104462D0
(sv)
|
2001-12-29 |
2001-12-29 |
Carlbiotech Ltd As |
Peptide purifcation (Peptidrening)
|
|
US8287864B2
(en)
|
2002-02-14 |
2012-10-16 |
Immunomedics, Inc. |
Structural variants of antibodies for improved therapeutic characteristics
|
|
CA2476166C
(en)
|
2002-02-14 |
2011-11-15 |
Immunomedics, Inc. |
Anti-cd20 antibodies and fusion proteins thereof and methods of use
|
|
US8435529B2
(en)
*
|
2002-06-14 |
2013-05-07 |
Immunomedics, Inc. |
Combining radioimmunotherapy and antibody-drug conjugates for improved cancer therapy
|
|
US8877901B2
(en)
*
|
2002-12-13 |
2014-11-04 |
Immunomedics, Inc. |
Camptothecin-binding moiety conjugates
|
|
US7591994B2
(en)
|
2002-12-13 |
2009-09-22 |
Immunomedics, Inc. |
Camptothecin-binding moiety conjugates
|
|
CA2478047C
(en)
|
2002-03-01 |
2014-01-21 |
Immunomedics, Inc. |
Rs7 antibodies
|
|
KR101017732B1
(ko)
|
2002-03-01 |
2011-02-28 |
이뮤노메딕스, 인코오포레이티드 |
내재화 항-ｃｄ74 항체 및 그 이용방법
|
|
FR2840532B1
(fr)
|
2002-06-11 |
2005-05-06 |
Ethypharm Sa |
Nanocapsules lipidiques furtives, procede de preparation et utilisation comme vecteur de principes(s) actif(s)
|
|
ES2524767T3
(es)
|
2002-06-14 |
2014-12-12 |
Immunomedics, Inc. |
Anticuerpo monoclonal humanizado HPAM4
|
|
US7906118B2
(en)
|
2005-04-06 |
2011-03-15 |
Ibc Pharmaceuticals, Inc. |
Modular method to prepare tetrameric cytokines with improved pharmacokinetics by the dock-and-lock (DNL) technology
|
|
WO2003106497A1
(en)
|
2002-06-14 |
2003-12-24 |
Immunomedics, Inc. |
Monoclonal antibody pam4 and its use for diagnosis and therapy of pancreatic cancer
|
|
KR101115797B1
(ko)
|
2002-08-01 |
2012-07-27 |
이뮤노메딕스, 인코오포레이티드 |
알파 태아 단백질 Ｉｍｍｕ31 항체 및 융합단백질, 및이들의 이용 방법
|
|
US7541440B2
(en)
|
2002-09-30 |
2009-06-02 |
Immunomedics, Inc. |
Chimeric, human and humanized anti-granulocyte antibodies and methods of use
|
|
KR20050065587A
(ko)
*
|
2002-10-08 |
2005-06-29 |
이뮤노메딕스, 인코오포레이티드 |
항체 치료법
|
|
US7217797B2
(en)
|
2002-10-15 |
2007-05-15 |
Pdl Biopharma, Inc. |
Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
|
|
CA2508831C
(en)
|
2002-12-13 |
2012-05-01 |
Immunomedics, Inc. |
Immunoconjugates with an intracellularly-cleavable linkage
|
|
US8420086B2
(en)
|
2002-12-13 |
2013-04-16 |
Immunomedics, Inc. |
Camptothecin conjugates of anti-CD22 antibodies for treatment of B cell diseases
|
|
US7534427B2
(en)
|
2002-12-31 |
2009-05-19 |
Immunomedics, Inc. |
Immunotherapy of B cell malignancies and autoimmune diseases using unconjugated antibodies and conjugated antibodies and antibody combinations and fusion proteins
|
|
US20040202666A1
(en)
|
2003-01-24 |
2004-10-14 |
Immunomedics, Inc. |
Anti-cancer anthracycline drug-antibody conjugates
|
|
US6875580B2
(en)
|
2003-01-28 |
2005-04-05 |
Schering Corporation |
Antibodies specific for plasmacytoid dendritic cells
|
|
JP4937751B2
(ja)
|
2003-06-13 |
2012-05-23 |
イミューノメディクス、インコーポレイテッド |
Ｄ−アミノ酸ペプチド
|
|
JP4733635B2
(ja)
|
2003-07-31 |
2011-07-27 |
イミューノメディクス、インコーポレイテッド |
抗ｃｄ１９抗体
|
|
US7902338B2
(en)
|
2003-07-31 |
2011-03-08 |
Immunomedics, Inc. |
Anti-CD19 antibodies
|
|
CA2534898A1
(en)
|
2003-08-08 |
2005-02-17 |
Immunomedics, Inc. |
Bispecific antibodies for inducing apoptosis of tumor and diseased cells
|
|
US8551480B2
(en)
|
2004-02-13 |
2013-10-08 |
Immunomedics, Inc. |
Compositions and methods of use of immunotoxins comprising ranpirnase (Rap) show potent cytotoxic activity
|
|
JP5150103B2
(ja)
|
2004-02-13 |
2013-02-20 |
イミューノメディクス、インコーポレイテッド |
組み換え細胞毒性ＲＮＡｓｅを含む融合タンパク質
|
|
US8003111B2
(en)
|
2005-04-06 |
2011-08-23 |
Ibc Pharmaceuticals, Inc. |
Dimeric alpha interferon pegylated site-specifically shows enhanced and prolonged efficacy in vivo
|
|
US8034352B2
(en)
|
2005-04-06 |
2011-10-11 |
Ibc Pharmaceuticals, Inc. |
Tetrameric cytokines with improved biological activity
|
|
TR201808537T4
(tr)
|
2004-09-23 |
2018-07-23 |
Genentech Inc |
Sistein değiştirilmiş antikorlar ve konjugatlar.
|
|
US7612153B2
(en)
|
2004-10-25 |
2009-11-03 |
Intezyne Technologies, Inc. |
Heterobifunctional poly(ethylene glycol) and uses thereof
|
|
US7251164B2
(en)
|
2004-11-10 |
2007-07-31 |
Innovative Silicon S.A. |
Circuitry for and method of improving statistical distribution of integrated circuits
|
|
CN101171034B
(zh)
|
2005-03-03 |
2014-06-18 |
免疫医疗公司 |
人源化l243抗体
|
|
US8349332B2
(en)
|
2005-04-06 |
2013-01-08 |
Ibc Pharmaceuticals, Inc. |
Multiple signaling pathways induced by hexavalent, monospecific and bispecific antibodies for enhanced toxicity to B-cell lymphomas and other diseases
|
|
CA2604032C
(en)
|
2005-04-06 |
2017-08-22 |
Ibc Pharmaceuticals, Inc. |
Methods for generating stably linked complexes composed of homodimers, homotetramers or dimers of dimers and uses
|
|
CN101534865A
(zh)
|
2005-10-19 |
2009-09-16 |
Ibc药品公司 |
生物活性装配体的制备方法及其用途
|
|
WO2007123995A2
(en)
|
2006-04-19 |
2007-11-01 |
Bionumerik Pharmaceuticals, Inc. |
Camptothecin-analog with a novel, “flipped” lactone-stable, e-ring and methods for making and using same
|
|
CN101506358B
(zh)
|
2006-05-15 |
2013-07-17 |
免疫医学股份有限公司 |
使用偶合的抗体或抗体片段治疗人免疫缺陷病毒感染的方法和组合物
|
|
WO2008101221A2
(en)
|
2007-02-16 |
2008-08-21 |
University Of Rochester |
Sonoelastographic shear velocity imaging using crawling wave excitation
|
|
ITTO20080313A1
(it)
|
2008-04-22 |
2009-10-23 |
Marco Colombatti |
Anticorpo monoclonale isolato o suo frammento legante l'antigene specifico di membrana della prostata, suoi coniugati e suoi usi
|
|
WO2010017500A2
(en)
*
|
2008-08-08 |
2010-02-11 |
Immunomedics, Inc. |
Anti-pancreatic cancer antibodies
|
|
WO2010022225A1
(en)
|
2008-08-20 |
2010-02-25 |
Ibc Pharmaceuticals, Inc. |
Dock-and-lock (dnl) vaccines for cancer therapy
|
|
JP2012516887A
(ja)
|
2009-02-05 |
2012-07-26 |
オンコックス・エッセ・エッレ・エッレ |
抗ｔｒｏｐ−２モノクローナル抗体ならびに腫瘍の治療および診断におけるその使用
|
|
PL3912643T3
(pl)
*
|
2009-02-13 |
2023-01-23 |
Immunomedics Inc. |
Immunokoniugaty z połączeniem rozszczepialnym wewnątrzkomórkowo
|
|
EA201200486A1
(ru)
|
2009-09-15 |
2012-08-30 |
Серулин Фарма Инк. |
Лечение онкологических заболеваний
|
|
EP2552483A4
(en)
*
|
2010-04-01 |
2013-09-25 |
Immunomedics Inc |
USE OF ANTIBODIES TO REDUCE THE NUMBER OF CELLS CONTAINING ANTIGENS AND DENDRITIC CELLS
|
|
EA201500220A1
(ru)
|
2010-05-17 |
2015-10-30 |
Ливтех, Инк. |
Антитело против trop-2 человека, обладающее противоопухолевой активностью in vivo
|
|
WO2011155579A1
(ja)
*
|
2010-06-10 |
2011-12-15 |
北海道公立大学法人札幌医科大学 |
抗Ｔｒｏｐ－２抗体
|
|
HUE031017T2
(en)
|
2011-04-01 |
2017-06-28 |
Wyeth Llc |
Antibody Drug Conjugates
|
|
AU2012250924B2
(en)
|
2011-05-02 |
2017-05-25 |
Immunomedics, Inc. |
Ultrafiltration concentration of allotype selected antibodies for small-volume administration
|
|
SG11201401699WA
(en)
|
2011-11-11 |
2014-09-26 |
Rinat Neuroscience Corp |
Antibodies specific for trop-2 and their uses
|
|
US9382329B2
(en)
|
2012-08-14 |
2016-07-05 |
Ibc Pharmaceuticals, Inc. |
Disease therapy by inducing immune response to Trop-2 expressing cells
|
|
CN107753954A
(zh)
*
|
2012-12-13 |
2018-03-06 |
免疫医疗公司 |
功效改进且毒性降低的抗体与sn‑38的免疫缀合物的剂量
|
|
US9492566B2
(en)
*
|
2012-12-13 |
2016-11-15 |
Immunomedics, Inc. |
Antibody-drug conjugates and uses thereof
|
|
US10137196B2
(en)
*
|
2012-12-13 |
2018-11-27 |
Immunomedics, Inc. |
Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity
|
|
US10413539B2
(en)
*
|
2012-12-13 |
2019-09-17 |
Immunomedics, Inc. |
Therapy for metastatic urothelial cancer with the antibody-drug conjugate, sacituzumab govitecan (IMMU-132)
|
|
US10195175B2
(en)
*
|
2015-06-25 |
2019-02-05 |
Immunomedics, Inc. |
Synergistic effect of anti-Trop-2 antibody-drug conjugate in combination therapy for triple-negative breast cancer when used with microtubule inhibitors or PARP inhibitors
|
|
US10669338B2
(en)
*
|
2016-06-17 |
2020-06-02 |
Immunomedics, Inc. |
Anti-PD-1 checkpoint inhibitor antibodies that block binding of PD-L1 to PD-1
|