|
US3927193A
(en)
|
1973-05-18 |
1975-12-16 |
Hoffmann La Roche |
Localization of tumors by radiolabelled antibodies
|
|
GB1541435A
(en)
|
1975-02-04 |
1979-02-28 |
Searle & Co |
Immunological materials
|
|
US4036945A
(en)
|
1976-05-03 |
1977-07-19 |
The Massachusetts General Hospital |
Composition and method for determining the size and location of myocardial infarcts
|
|
US4200690A
(en)
|
1976-12-16 |
1980-04-29 |
Millipore Corporation |
Immunoassay with membrane immobilized antibody
|
|
US4361544A
(en)
|
1980-03-03 |
1982-11-30 |
Goldenberg Milton David |
Tumor localization and therapy with labeled antibodies specific to intracellular tumor-associated markers
|
|
US4348376A
(en)
|
1980-03-03 |
1982-09-07 |
Goldenberg Milton David |
Tumor localization and therapy with labeled anti-CEA antibody
|
|
US4331647A
(en)
|
1980-03-03 |
1982-05-25 |
Goldenberg Milton David |
Tumor localization and therapy with labeled antibody fragments specific to tumor-associated markers
|
|
US4444744A
(en)
|
1980-03-03 |
1984-04-24 |
Goldenberg Milton David |
Tumor localization and therapy with labeled antibodies to cell surface antigens
|
|
US5204095A
(en)
|
1980-04-09 |
1993-04-20 |
National Research Development Corporation |
Monoclonal antibodies against hepatitis B virus
|
|
US4359457A
(en)
|
1980-09-30 |
1982-11-16 |
Neville Jr David M |
Anti Thy 1.2 monoclonal antibody-ricin hybrid utilized as a tumor suppressant
|
|
US4554101A
(en)
|
1981-01-09 |
1985-11-19 |
New York Blood Center, Inc. |
Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity
|
|
US4468457A
(en)
|
1981-06-01 |
1984-08-28 |
David M. Goldenberg |
Method for producing a CSAp tryptic peptide and anti-CSAp antibodies
|
|
US4818709A
(en)
|
1983-01-21 |
1989-04-04 |
Primus Frederick J |
CEA-family antigens, Anti-CEA antibodies and CEA immunoassay
|
|
US4916213A
(en)
|
1983-02-22 |
1990-04-10 |
Xoma Corporation |
Ribosomal inhibiting protein-immunoglobulin conjugates with specificity for tumor cell surface antigens, and mixtures thereof
|
|
US4925922A
(en)
|
1983-02-22 |
1990-05-15 |
Xoma Corporation |
Potentiation of cytotoxic conjugates
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US4624846A
(en)
|
1983-07-29 |
1986-11-25 |
Immunomedics, Inc. |
Method for enhancing target specificity of antibody localization and clearance of non-target diagnostic and therapeutic principles
|
|
US5672347A
(en)
|
1984-07-05 |
1997-09-30 |
Genentech, Inc. |
Tumor necrosis factor antagonists and their use
|
|
US4824659A
(en)
|
1985-06-07 |
1989-04-25 |
Immunomedics, Inc. |
Antibody conjugates
|
|
US5525338A
(en)
|
1992-08-21 |
1996-06-11 |
Immunomedics, Inc. |
Detection and therapy of lesions with biotin/avidin conjugates
|
|
US5776093A
(en)
|
1985-07-05 |
1998-07-07 |
Immunomedics, Inc. |
Method for imaging and treating organs and tissues
|
|
US4918163A
(en)
|
1985-09-27 |
1990-04-17 |
Pfizer Inc. |
Monoclonal antibodies specific for lipid-A determinants of gram negative bacteria
|
|
US5618920A
(en)
|
1985-11-01 |
1997-04-08 |
Xoma Corporation |
Modular assembly of antibody genes, antibodies prepared thereby and use
|
|
US4699784A
(en)
|
1986-02-25 |
1987-10-13 |
Center For Molecular Medicine & Immunology |
Tumoricidal methotrexate-antibody conjugate
|
|
US5057313A
(en)
|
1986-02-25 |
1991-10-15 |
The Center For Molecular Medicine And Immunology |
Diagnostic and therapeutic antibody conjugates
|
|
US6861511B1
(en)
|
1986-06-04 |
2005-03-01 |
Bayer Corporation |
Detection and quantification of neu related proteins in the biological fluids of humans
|
|
US4997913A
(en)
|
1986-06-30 |
1991-03-05 |
Oncogen |
pH-sensitive immunoconjugates and methods for their use in tumor therapy
|
|
US4946778A
(en)
|
1987-09-21 |
1990-08-07 |
Genex Corporation |
Single polypeptide chain binding molecules
|
|
US4704692A
(en)
|
1986-09-02 |
1987-11-03 |
Ladner Robert C |
Computer based system and method for determining and displaying possible chemical structures for converting double- or multiple-chain polypeptides to single-chain polypeptides
|
|
US5567610A
(en)
|
1986-09-04 |
1996-10-22 |
Bioinvent International Ab |
Method of producing human monoclonal antibodies and kit therefor
|
|
US6893625B1
(en)
|
1986-10-27 |
2005-05-17 |
Royalty Pharma Finance Trust |
Chimeric antibody with specificity to human B cell surface antigen
|
|
CA1320905C
(en)
|
1986-11-06 |
1993-08-03 |
Joseph M. Cummins |
Treatment of immuno-resistant disease
|
|
US4932412A
(en)
|
1986-12-18 |
1990-06-12 |
Immunomedics, Inc. |
Intraoperative and endoscopic tumor detection and therapy
|
|
IL85035A0
(en)
|
1987-01-08 |
1988-06-30 |
Int Genetic Eng |
Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
|
|
WO1988007553A1
(fr)
|
1987-03-26 |
1988-10-06 |
Teijin Limited |
Procede de preparation d'un complexe d'anticorps
|
|
US5132405A
(en)
|
1987-05-21 |
1992-07-21 |
Creative Biomolecules, Inc. |
Biosynthetic antibody binding sites
|
|
US4981979A
(en)
|
1987-09-10 |
1991-01-01 |
Neorx Corporation |
Immunoconjugates joined by thioether bonds having reduced toxicity and improved selectivity
|
|
US5831034A
(en)
|
1987-11-13 |
1998-11-03 |
Hermann Katinger |
Human monoclonal anti-HIV-I-antibodies
|
|
US6511665B1
(en)
|
1987-11-25 |
2003-01-28 |
Immunex Corporation |
Antibodies to interleukin-1 receptors
|
|
FI102355B1
(fi)
|
1988-02-11 |
1998-11-30 |
Bristol Myers Squibb Co |
Menetelmä yhdistävän välikappaleen omaavien antrasykliini-immunokonjugaattien valmistamiseksi
|
|
US5112954A
(en)
|
1988-02-26 |
1992-05-12 |
Neorx Corporation |
Method of enhancing the effect of cytotoxic agents
|
|
US4861579A
(en)
|
1988-03-17 |
1989-08-29 |
American Cyanamid Company |
Suppression of B-lymphocytes in mammals by administration of anti-B-lymphocyte antibodies
|
|
US5120525A
(en)
|
1988-03-29 |
1992-06-09 |
Immunomedics, Inc. |
Radiolabeled antibody cytotoxic therapy of cancer
|
|
US5612016A
(en)
|
1988-04-01 |
1997-03-18 |
Immunomedics, Inc. |
Conjugates of antibodies and bifunctional ligands
|
|
US5541297A
(en)
|
1988-04-01 |
1996-07-30 |
Immunomedics, Inc. |
Therapeutic conjugates of toxins and drugs
|
|
US5453359A
(en)
|
1988-06-13 |
1995-09-26 |
American Biogenetic Sciences, Inc. |
Immunoassay and kit for in vitro detection of soluble DesAABB fibrin polymers
|
|
US4925648A
(en)
|
1988-07-29 |
1990-05-15 |
Immunomedics, Inc. |
Detection and treatment of infectious and inflammatory lesions
|
|
US5439665A
(en)
|
1988-07-29 |
1995-08-08 |
Immunomedics |
Detection and treatment of infectious and inflammatory lesions
|
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
|
US6362325B1
(en)
|
1988-11-07 |
2002-03-26 |
Advanced Research And Technology Institute, Inc. |
Murine 4-1BB gene
|
|
US6352694B1
(en)
|
1994-06-03 |
2002-03-05 |
Genetics Institute, Inc. |
Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells
|
|
US5571714A
(en)
|
1988-12-22 |
1996-11-05 |
Celtrix Pharmaceuticals, Inc. |
Monoclonal antibodies which bind both transforming growth factors β1 and β2 and methods of use
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
GB8903021D0
(en)
|
1989-02-10 |
1989-03-30 |
Celltech Ltd |
Chemical compounds
|
|
US5134075A
(en)
|
1989-02-17 |
1992-07-28 |
Oncogen Limited Partnership |
Monoclonal antibody to novel antigen associated with human tumors
|
|
US5171665A
(en)
|
1989-04-17 |
1992-12-15 |
Oncogen |
Monoclonal antibody to novel antigen associated with human tumors
|
|
JPH02283294A
(ja)
|
1989-04-24 |
1990-11-20 |
Sumitomo Chem Co Ltd |
ヒトモノクローナル抗体
|
|
US6432402B1
(en)
|
1989-05-25 |
2002-08-13 |
Sloan-Kettering Institute For Cancer Research |
Anti-idiotypic antibody which induces an immune response against a glycosphingolipid and use thereof
|
|
WO1990015076A2
(en)
|
1989-06-02 |
1990-12-13 |
The Johns Hopkins University School Of Medicine |
MONOCLONAL ANTIBODIES AGAINST LEUKOCYTE ADHESION RECEPTOR β-CHAIN, METHODS OF PRODUCING THESE ANTIBODIES AND USE THEREFORE
|
|
US5332567A
(en)
|
1989-08-24 |
1994-07-26 |
Immunomedics |
Detection and treatment of infections with immunoconjugates
|
|
SG46445A1
(en)
|
1990-01-26 |
1998-02-20 |
Immunomedics Inc |
Vaccines against cancer and infectious diseases
|
|
IL97459A0
(en)
|
1990-03-09 |
1992-06-21 |
Hybritech Inc |
Trifunctional antibody-like compounds as a combined diagnostic and therapeutic agent
|
|
WO1991013974A1
(en)
|
1990-03-14 |
1991-09-19 |
The Biomembrane Institute |
Monoclonal antibody and immunoconjugates for the treatment and detection of b cell disorders
|
|
US7041293B1
(en)
|
1990-04-03 |
2006-05-09 |
Genentech, Inc. |
HIV env antibodies
|
|
US5229275A
(en)
|
1990-04-26 |
1993-07-20 |
Akzo N.V. |
In-vitro method for producing antigen-specific human monoclonal antibodies
|
|
US5252296A
(en)
|
1990-05-15 |
1993-10-12 |
Chiron Corporation |
Method and apparatus for biopolymer synthesis
|
|
US5496938A
(en)
|
1990-06-11 |
1996-03-05 |
Nexstar Pharmaceuticals, Inc. |
Nucleic acid ligands to HIV-RT and HIV-1 rev
|
|
US5637459A
(en)
|
1990-06-11 |
1997-06-10 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: chimeric selex
|
|
EP1695978A1
(en)
|
1990-06-11 |
2006-08-30 |
Gilead Sciences, Inc. |
Nucleic acid ligands
|
|
US5270163A
(en)
|
1990-06-11 |
1993-12-14 |
University Research Corporation |
Methods for identifying nucleic acid ligands
|
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
GB9020075D0
(en)
|
1990-09-14 |
1990-10-24 |
Filler Aaron G |
Contrast agents for magnetic resonance imaging of axonal transport
|
|
US5679640A
(en)
|
1991-02-12 |
1997-10-21 |
Cytel Corporation |
Immunosuppressant peptides
|
|
JP3105629B2
(ja)
|
1991-04-23 |
2000-11-06 |
サングスタット メディカル コーポレイション |
特異的結合ペアのメンバーの細胞活性調節接合体
|
|
US5364612A
(en)
|
1991-05-06 |
1994-11-15 |
Immunomedics, Inc. |
Detection of cardiovascular lesions
|
|
MX9204374A
(es)
|
1991-07-25 |
1993-03-01 |
Idec Pharma Corp |
Anticuerpo recombinante y metodo para su produccion.
|
|
US5582981A
(en)
|
1991-08-14 |
1996-12-10 |
Gilead Sciences, Inc. |
Method for identifying an oligonucleotide aptamer specific for a target
|
|
JP3951062B2
(ja)
|
1991-09-19 |
2007-08-01 |
ジェネンテック・インコーポレーテッド |
少なくとも遊離のチオールとして存在するシステインを有する抗体フラグメントの大腸菌での発現、２官能性Ｆ（ａｂ’）２抗体の産生のための使用
|
|
US6764681B2
(en)
|
1991-10-07 |
2004-07-20 |
Biogen, Inc. |
Method of prophylaxis or treatment of antigen presenting cell driven skin conditions using inhibitors of the CD2/LFA-3 interaction
|
|
US5854416A
(en)
|
1991-11-14 |
1998-12-29 |
The United States Of America As Represented By The Department Of Health And Human Services |
Streptococcus pneumoniae 37-KDA surface adhesin a protein and nucleic acids coding therefor
|
|
US5474771A
(en)
|
1991-11-15 |
1995-12-12 |
The Trustees Of Columbia University In The City Of New York |
Murine monoclonal antibody (5c8) recognizes a human glycoprotein on the surface of T-lymphocytes, compositions containing same
|
|
US5622929A
(en)
|
1992-01-23 |
1997-04-22 |
Bristol-Myers Squibb Company |
Thioether conjugates
|
|
AU3657693A
(en)
|
1992-01-29 |
1993-09-01 |
Regents Of The University Of California, The |
Carcinoma associated antigen (SK1) monoclonal antibodies against SK1, methods of producing these antibodies and use therfor
|
|
US5965132A
(en)
|
1992-03-05 |
1999-10-12 |
Board Of Regents, The University Of Texas System |
Methods and compositions for targeting the vasculature of solid tumors
|
|
DE69333348T2
(de)
|
1992-03-09 |
2004-09-16 |
San Diego Regional Cancer Center, San Diego |
Anti-idiotypischer Antikörper und seine Verwendung zur Diagnose und Therapie bei HIV-bezogenen Krankheiten
|
|
US6129914A
(en)
|
1992-03-27 |
2000-10-10 |
Protein Design Labs, Inc. |
Bispecific antibody effective to treat B-cell lymphoma and cell line
|
|
DE69322860T2
(de)
|
1992-04-03 |
1999-07-01 |
Genentech, Inc., South San Francisco, Calif. |
Antikörper gegen alpha v beta 3 integrin
|
|
US6096289A
(en)
|
1992-05-06 |
2000-08-01 |
Immunomedics, Inc. |
Intraoperative, intravascular, and endoscopic tumor and lesion detection, biopsy and therapy
|
|
EP0643583B1
(en)
|
1992-05-06 |
2000-07-26 |
Immunomedics, Inc. |
Intraoperative, intravascular and endoscopic tumor and lesion detection and therapy
|
|
AU4231393A
(en)
|
1992-05-08 |
1993-12-13 |
Genentech Inc. |
Antibodies to leukemia inhibitory factor
|
|
US5686072A
(en)
|
1992-06-17 |
1997-11-11 |
Board Of Regents, The University Of Texas |
Epitope-specific monoclonal antibodies and immunotoxins and uses thereof
|
|
US5397703A
(en)
|
1992-07-09 |
1995-03-14 |
Cetus Oncology Corporation |
Method for generation of antibodies to cell surface molecules
|
|
PT752248E
(pt)
|
1992-11-13 |
2001-01-31 |
Idec Pharma Corp |
Aplicacao terapeutica de anticorpos quimericos e marcados radioactivamente contra antigenios de diferenciacao restrita de linfocitos b humanos para o tratamento do linfoma de celulas b
|
|
MX9401351A
(es)
|
1993-02-22 |
1994-08-31 |
Alza Corp |
Composiciones para suministro oral para agentes activos.
|
|
US6214345B1
(en)
|
1993-05-14 |
2001-04-10 |
Bristol-Myers Squibb Co. |
Lysosomal enzyme-cleavable antitumor drug conjugates
|
|
CA2163107C
(en)
|
1993-05-17 |
2001-04-17 |
David Milton Goldenberg |
Improved detection and therapy of lesions with biotin/avidin-metal chelating protein conjugates
|
|
US6120768A
(en)
|
1993-05-17 |
2000-09-19 |
Immunomedics, Inc. |
Dota-biotin derivatives
|
|
US5484892A
(en)
|
1993-05-21 |
1996-01-16 |
Dana-Farber Cancer Institute, Inc. |
Monoclonal antibodies that block ligand binding to the CD22 receptor in mature B cells
|
|
CA2163976C
(en)
|
1993-05-28 |
2010-06-29 |
Didier J. Leturcq |
Methods and compositions for inhibiting cd14 mediated cell activation
|
|
US5565215A
(en)
|
1993-07-23 |
1996-10-15 |
Massachusettes Institute Of Technology |
Biodegradable injectable particles for imaging
|
|
US6084067A
(en)
|
1993-07-26 |
2000-07-04 |
Dana-Farber Cancer Institute |
CTLA4/CD28 ligands and uses therefor
|
|
US5417972A
(en)
|
1993-08-02 |
1995-05-23 |
The Board Of Trustees Of The Leland Stanford Junior University |
Method of killing B-cells in a complement independent and an ADCC independent manner using antibodies which specifically bind CDIM
|
|
UA40577C2
(uk)
|
1993-08-02 |
2001-08-15 |
Мерк Патент Гмбх |
Біспецифічна молекула, що використовується для лізису пухлинних клітин, спосіб її одержання, моноклональне антитіло (варіанти), фармацевтичний препарат, фармацевтичний набір (варіанти), спосіб видалення пухлинних клітин
|
|
US6468531B1
(en)
|
1993-09-09 |
2002-10-22 |
Duke University |
Method of promoting cellular function
|
|
WO1995009917A1
(en)
|
1993-10-07 |
1995-04-13 |
The Regents Of The University Of California |
Genetically engineered bispecific tetravalent antibodies
|
|
US5824701A
(en)
|
1993-10-20 |
1998-10-20 |
Enzon, Inc. |
Taxane-based prodrugs
|
|
US5492807A
(en)
|
1993-11-19 |
1996-02-20 |
Santi; Daniel V. |
Method of obtaining diagnostic reagents, assays and therapeutics based on clinical manifestations of a disease
|
|
WO1995014040A1
(en)
|
1993-11-19 |
1995-05-26 |
Baylor College Of Medicine |
Monoclonal antibodies specific for human interleukin-5
|
|
US5443953A
(en)
|
1993-12-08 |
1995-08-22 |
Immunomedics, Inc. |
Preparation and use of immunoconjugates
|
|
US6432404B1
(en)
|
1993-12-23 |
2002-08-13 |
Icos Corporation |
Methods of inhibiting locomotor damage following spinal cord injury with α D-specific antibodies
|
|
US5922572A
(en)
|
1994-01-25 |
1999-07-13 |
Human Genome Sciences, Inc. |
Polynucleotides encoding haemopoietic maturation factor
|
|
US5487892A
(en)
|
1994-02-24 |
1996-01-30 |
American Biogenetic Sciences, Inc. |
Method for treating thrombotic disease using a fibrin specific monoclonal antibody
|
|
US5639725A
(en)
|
1994-04-26 |
1997-06-17 |
Children's Hospital Medical Center Corp. |
Angiostatin protein
|
|
US6074642A
(en)
|
1994-05-02 |
2000-06-13 |
Alexion Pharmaceuticals, Inc. |
Use of antibodies specific to human complement component C5 for the treatment of glomerulonephritis
|
|
US6100389A
(en)
|
1995-04-21 |
2000-08-08 |
Human Genome Sciences, Inc. |
Polynucleotides encoding a human chemotactic protein
|
|
US5798100A
(en)
|
1994-07-06 |
1998-08-25 |
Immunomedics, Inc. |
Multi-stage cascade boosting vaccine
|
|
US6303769B1
(en)
|
1994-07-08 |
2001-10-16 |
Immunex Corporation |
Lerk-5 dna
|
|
US5686578A
(en)
|
1994-08-05 |
1997-11-11 |
Immunomedics, Inc. |
Polyspecific immunoconjugates and antibody composites for targeting the multidrug resistant phenotype
|
|
DE69534530T2
(de)
|
1994-08-12 |
2006-07-06 |
Immunomedics, Inc. |
Für b-zell-lymphom und leukämiezellen spezifische immunkonjugate und humane antikörper
|
|
US8771694B2
(en)
|
1994-08-12 |
2014-07-08 |
Immunomedics, Inc. |
Immunoconjugates and humanized antibodies specific for B-cell lymphoma and leukemia cells
|
|
US5587459A
(en)
|
1994-08-19 |
1996-12-24 |
Regents Of The University Of Minnesota |
Immunoconjugates comprising tyrosine kinase inhibitors
|
|
US6174995B1
(en)
|
1994-08-23 |
2001-01-16 |
Haodong Li |
Human chemokines, CKβ4 and CKβ10/MCP-4
|
|
US6458349B1
(en)
|
1995-06-02 |
2002-10-01 |
Human Genome Sciences, Inc. |
Chemokine β-4 polypeptides
|
|
US6709653B1
(en)
|
1994-09-16 |
2004-03-23 |
Human Genome Sciences, Inc. |
Antibodies specific for human inositol monophosphatase H1
|
|
US5874540A
(en)
|
1994-10-05 |
1999-02-23 |
Immunomedics, Inc. |
CDR-grafted type III anti-CEA humanized mouse monoclonal antibodies
|
|
US5750370A
(en)
|
1995-06-06 |
1998-05-12 |
Human Genome Sciences, Inc. |
Nucleic acid encoding human endothlein-bombesin receptor and method of producing the receptor
|
|
US6538121B1
(en)
|
1994-11-01 |
2003-03-25 |
Human Genome Sciences, Inc. |
Interleukin-1 β converting enzyme like apoptosis protease-3 and 4
|
|
US5677136A
(en)
|
1994-11-14 |
1997-10-14 |
Systemix, Inc. |
Methods of obtaining compositions enriched for hematopoietic stem cells, compositions derived therefrom and methods of use thereof
|
|
US6521227B1
(en)
|
1999-11-18 |
2003-02-18 |
Peter L. Hudson |
Polynucleotides encoding prostatic growth factor and process for producing prostatic growth factor polypeptides
|
|
US6537764B1
(en)
|
1995-01-19 |
2003-03-25 |
Children's Medical Center Corporation |
Method of identifying inhibitors of C—C chemokine receptor 3
|
|
US5786204A
(en)
|
1995-01-20 |
1998-07-28 |
Human Genome Sciences, Inc. |
Human prostatic specific reductase
|
|
US6312691B1
(en)
|
1996-01-26 |
2001-11-06 |
Jeffrey L. Browning |
Lymphotoxin-α/β complexes and anti-lympotoxin-β receptor antibodies as anti-tumor agents
|
|
US6949244B1
(en)
|
1995-12-20 |
2005-09-27 |
The Board Of Trustees Of The University Of Kentucky |
Murine monoclonal anti-idiotype antibody 11D10 and methods of use thereof
|
|
US5798554A
(en)
|
1995-02-24 |
1998-08-25 |
Consorzio Per La Ricerca Sulla Microelettronica Nel Mezzogiorno |
MOS-technology power device integrated structure and manufacturing process thereof
|
|
US5783404A
(en)
|
1995-04-13 |
1998-07-21 |
Amgen Inc. |
Methods and compositions for determining HER-2/neu expression using monoclonal antibodies
|
|
ATE219105T1
(de)
|
1995-04-19 |
2002-06-15 |
Polymun Scient Immunbio Forsch |
Monoklonale antikörper gegen hiv-1 und davon hergestellte impfstoffe
|
|
AUPO591797A0
(en)
|
1997-03-27 |
1997-04-24 |
Commonwealth Scientific And Industrial Research Organisation |
High avidity polyvalent and polyspecific reagents
|
|
US5686292A
(en)
|
1995-06-02 |
1997-11-11 |
Genentech, Inc. |
Hepatocyte growth factor receptor antagonist antibodies and uses thereof
|
|
US5773292A
(en)
|
1995-06-05 |
1998-06-30 |
Cornell University |
Antibodies binding portions, and probes recognizing an antigen of prostate epithelial cells but not antigens circulating in the blood
|
|
US5773252A
(en)
|
1995-06-05 |
1998-06-30 |
Human Genome Sciences, Inc. |
Fibroblast growth factor 15
|
|
US6605441B1
(en)
|
1995-06-05 |
2003-08-12 |
Human Genome Sciences, Inc. |
Antibodies against fibroblast growth factor 11
|
|
WO1996040875A1
(en)
|
1995-06-07 |
1996-12-19 |
Novartis Ag |
Methods for obtaining compositions enriched for hematopoietic stem cells and antibodies for use therein
|
|
US5622699A
(en)
|
1995-09-11 |
1997-04-22 |
La Jolla Cancer Research Foundation |
Method of identifying molecules that home to a selected organ in vivo
|
|
US6068829A
(en)
|
1995-09-11 |
2000-05-30 |
The Burnham Institute |
Method of identifying molecules that home to a selected organ in vivo
|
|
US6340459B1
(en)
|
1995-12-01 |
2002-01-22 |
The Trustees Of Columbia University In The City Of New York |
Therapeutic applications for the anti-T-BAM (CD40-L) monoclonal antibody 5C8 in the treatment of reperfusion injury in non-transplant recipients
|
|
US5783186A
(en)
|
1995-12-05 |
1998-07-21 |
Amgen Inc. |
Antibody-induced apoptosis
|
|
US6441025B2
(en)
|
1996-03-12 |
2002-08-27 |
Pg-Txl Company, L.P. |
Water soluble paclitaxel derivatives
|
|
US5945309A
(en)
|
1996-03-19 |
1999-08-31 |
Human Genome Sciences, Inc. |
Cytostatin III nucleic acids encoding
|
|
WO1997034632A1
(en)
|
1996-03-20 |
1997-09-25 |
Immunomedics, Inc. |
Glycosylated humanized b-cell specific antibodies
|
|
EP0939653B1
(en)
|
1996-03-20 |
2005-08-31 |
Immunomedics, Inc. |
Humanization of an anti-carcinoembryonic antigen anti-idiotype antibody and use as a tumor vaccine and for targeting applications
|
|
FR2746398B1
(fr)
|
1996-03-21 |
1998-04-30 |
Bio Merieux |
Anticorps specifique de staphylococcus aureaus, et utilisations
|
|
US6174992B1
(en)
|
1997-03-21 |
2001-01-16 |
Human Genome Sciences, Inc. |
Human endometrial specific steroid-binding factor I, II and III
|
|
US6962981B1
(en)
|
1996-03-25 |
2005-11-08 |
Medarex, Inc. |
Monoclonal antibodies specific for the extracellular domain of prostate-specific membrane antigen
|
|
US6004780A
(en)
|
1996-03-26 |
1999-12-21 |
Human Genome Sciences, Inc. |
Growth factor HTTER36
|
|
US6110463A
(en)
|
1996-03-29 |
2000-08-29 |
North Carolina State University |
Anti-Cryptosporidium parvum preparations
|
|
US6066617A
(en)
|
1996-04-03 |
2000-05-23 |
Human Genome Sciences, Inc. |
Human cystatin F
|
|
DE69737867T2
(de)
|
1996-05-03 |
2007-10-18 |
Immunomedics, Inc. |
Zielgerichtete kombinations-immuntherapie für krebs
|
|
US6107090A
(en)
|
1996-05-06 |
2000-08-22 |
Cornell Research Foundation, Inc. |
Treatment and diagnosis of prostate cancer with antibodies to extracellur PSMA domains
|
|
US6136311A
(en)
|
1996-05-06 |
2000-10-24 |
Cornell Research Foundation, Inc. |
Treatment and diagnosis of cancer
|
|
JP2000516594A
(ja)
|
1996-07-26 |
2000-12-12 |
スミスクライン・ビーチャム・コーポレイション |
免疫細胞介在全身性疾患の改良された治療法
|
|
WO1998010055A1
(en)
|
1996-09-03 |
1998-03-12 |
Kaneka Corporation |
Method for inducing immunosuppressive cells and culturing device to be used therefor
|
|
DE19640207A1
(de)
|
1996-09-30 |
1998-04-02 |
Bayer Ag |
Glycokonjugate von modifizierten Camptothecin-Derivaten (A- oder B-Ring-Verknüpfung)
|
|
US6479247B1
(en)
|
1996-10-09 |
2002-11-12 |
The Corporation Of The Trustees Of The Order Of The Sisters Of Mercy In Queensland |
Dendritic cell-specific antibodies
|
|
US6056973A
(en)
|
1996-10-11 |
2000-05-02 |
Sequus Pharmaceuticals, Inc. |
Therapeutic liposome composition and method of preparation
|
|
DE69719529T2
(de)
|
1996-10-17 |
2003-12-11 |
Immunomedics, Inc. |
Nichtantigenes toxinkonjugat und fusionsprotein eines internalisierendes rezeptorsystems
|
|
US6653104B2
(en)
|
1996-10-17 |
2003-11-25 |
Immunomedics, Inc. |
Immunotoxins, comprising an internalizing antibody, directed against malignant and normal cells
|
|
US6812327B1
(en)
|
1996-10-25 |
2004-11-02 |
Human Genome Sciences, Inc. |
Neutrokine-alpha polypeptides
|
|
US6528625B1
(en)
|
1996-10-28 |
2003-03-04 |
Millennium Pharmaceuticals, Inc. |
Anti-CCR5 antibodies and kits comprising same
|
|
WO1998021334A2
(en)
|
1996-11-13 |
1998-05-22 |
Morphogenesis, Inc. |
Antibody mg1 recognizing a small subset of human hematopoietic cells
|
|
US6455040B1
(en)
|
1997-01-14 |
2002-09-24 |
Human Genome Sciences, Inc. |
Tumor necrosis factor receptor 5
|
|
US6605699B1
(en)
|
1997-01-21 |
2003-08-12 |
Human Genome Sciences, Inc. |
Galectin-11 polypeptides
|
|
EP0988385A2
(en)
|
1997-01-21 |
2000-03-29 |
Human Genome Sciences |
Tace-like and matrilysin-like polypeptides
|
|
PT1012274E
(pt)
|
1997-01-28 |
2007-08-14 |
Craig A Rosen |
Receptor 4 contendo um domínio de morte (dm4; receptor de morte 4), membro da super-família do ftn e ligação a liart (ap02)
|
|
US7122636B1
(en)
|
1997-02-21 |
2006-10-17 |
Genentech, Inc. |
Antibody fragment-polymer conjugates and uses of same
|
|
WO1998043089A1
(en)
|
1997-03-03 |
1998-10-01 |
Bristol-Myers Squibb Company |
Monoclonal antibodies to human cd6
|
|
US6919433B2
(en)
|
1997-03-14 |
2005-07-19 |
Human Genome Sciences, Inc. |
Antibodies to protein HPMBQ91
|
|
US6951924B2
(en)
|
1997-03-14 |
2005-10-04 |
Human Genome Sciences, Inc. |
Antibodies against secreted protein HTEBYII
|
|
US6872568B1
(en)
|
1997-03-17 |
2005-03-29 |
Human Genome Sciences, Inc. |
Death domain containing receptor 5 antibodies
|
|
US6306393B1
(en)
|
1997-03-24 |
2001-10-23 |
Immunomedics, Inc. |
Immunotherapy of B-cell malignancies using anti-CD22 antibodies
|
|
US6183744B1
(en)
|
1997-03-24 |
2001-02-06 |
Immunomedics, Inc. |
Immunotherapy of B-cell malignancies using anti-CD22 antibodies
|
|
ES2248898T3
(es)
|
1997-05-02 |
2006-03-16 |
The Government Of The Usa, As Represented By The Secretary, Department Of Health And Human Services |
Inmunotoxinas que comprenden una proteina onc dirigida contra celulas malignas.
|
|
US6284474B1
(en)
|
1998-04-23 |
2001-09-04 |
The Regents Of The University Of California |
Detection and diagnosis of conditions associated with lung injury
|
|
US6372217B1
(en)
|
1997-06-03 |
2002-04-16 |
Regents Of The University Of Minnesota |
Methods for the treatment of CD7+ viral infection with TXU-7-PAP
|
|
US6545130B2
(en)
|
1997-06-04 |
2003-04-08 |
Albert Einstein College Of Medicine Of Yeshiva University |
Monoclonal antibodies to mycobacterium tuberculosis and a modified ELISA assay
|
|
US6358508B1
(en)
|
1997-06-11 |
2002-03-19 |
Human Genome Sciences, Inc. |
Antibodies to human tumor necrosis factor receptor TR9
|
|
AU8296098A
(en)
|
1997-07-08 |
1999-02-08 |
Board Of Regents, The University Of Texas System |
Compositions and methods for homoconjugates of antibodies which induce growth arrest or apoptosis of tumor cells
|
|
US6165440A
(en)
|
1997-07-09 |
2000-12-26 |
Board Of Regents, The University Of Texas System |
Radiation and nanoparticles for enhancement of drug delivery in solid tumors
|
|
DE69839401T2
(de)
|
1997-09-18 |
2009-05-07 |
Genentech Inc., San Francisco |
Dcr3 polypeptid, ein tnfr homolog
|
|
US6689607B2
(en)
|
1997-10-21 |
2004-02-10 |
Human Genome Sciences, Inc. |
Human tumor, necrosis factor receptor-like proteins TR11, TR11SV1 and TR11SV2
|
|
US6355244B1
(en)
|
1997-11-17 |
2002-03-12 |
University Of Kentucky Research Foundation |
Methods and compositions for the treatment of psoriasis
|
|
US6610833B1
(en)
|
1997-11-24 |
2003-08-26 |
The Institute For Human Genetics And Biochemistry |
Monoclonal human natural antibodies
|
|
AU1682699A
(en)
|
1997-12-25 |
1999-07-19 |
Japan Tobacco Inc. |
Monoclonal antibody against connective tissue growth factor and medicinal uses thereof
|
|
US6051228A
(en)
|
1998-02-19 |
2000-04-18 |
Bristol-Myers Squibb Co. |
Antibodies against human CD40
|
|
US6956107B2
(en)
|
1998-02-20 |
2005-10-18 |
Tanox, Inc. |
Inhibitors of complement activation
|
|
US6861227B2
(en)
|
1998-03-19 |
2005-03-01 |
Human Genome Sciences, Inc. |
Antibodies to cytokine receptor common gamma chain like
|
|
WO1999054440A1
(en)
|
1998-04-21 |
1999-10-28 |
Micromet Gesellschaft Für Biomedizinische Forschung Mbh |
CD19xCD3 SPECIFIC POLYPEPTIDES AND USES THEREOF
|
|
US6200765B1
(en)
|
1998-05-04 |
2001-03-13 |
Pacific Northwest Cancer Foundation |
Non-invasive methods to detect prostate cancer
|
|
EP1079862B1
(en)
|
1998-05-20 |
2010-07-07 |
Immunomedics, Inc. |
Therapeutics using a bispecific anti-hla class ii invariant chain x anti-pathogen antibody
|
|
IL139700A
(en)
|
1998-06-15 |
2005-09-25 |
Altarex Medical Corp |
Immunotherapeutic composition for the treatment of prostate cancer
|
|
US7387779B2
(en)
|
1998-06-17 |
2008-06-17 |
Beth Israel Deaconess Medical Center |
Anti-angiogenic proteins and fragments and methods of use thereof
|
|
US6528269B1
(en)
|
1998-06-22 |
2003-03-04 |
Case Western Reserve University |
Immunological agents specific for prion protein (PRP)
|
|
US7387772B1
(en)
|
1999-06-22 |
2008-06-17 |
Immunimedics, Inc. |
Chimeric, human and humanized anti-CSAP monoclonal antibodies
|
|
US7405320B2
(en)
|
1998-06-22 |
2008-07-29 |
Immunomedics, Inc. |
Therapeutic and diagnostic conjugates for use with multispecific antibodies
|
|
US7138103B2
(en)
|
1998-06-22 |
2006-11-21 |
Immunomedics, Inc. |
Use of bi-specific antibodies for pre-targeting diagnosis and therapy
|
|
US6962702B2
(en)
|
1998-06-22 |
2005-11-08 |
Immunomedics Inc. |
Production and use of novel peptide-based agents for use with bi-specific antibodies
|
|
US6312689B1
(en)
|
1998-07-23 |
2001-11-06 |
Millennium Pharmaceuticals, Inc. |
Anti-CCR2 antibodies and methods of use therefor
|
|
AUPP525198A0
(en)
|
1998-08-13 |
1998-09-03 |
Medvet Science Pty. Ltd. |
Monoclonal antibody inhibitor of GM-CSF, IL-3 and IL-5 and other cytokines and uses thereof
|
|
US6572856B1
(en)
|
1998-09-10 |
2003-06-03 |
The University Of Virginia Patent Foundation |
Methods for the prevention and treatment of cancer using anti-C3b(i) antibodies
|
|
US6818749B1
(en)
|
1998-10-31 |
2004-11-16 |
The United States Of America As Represented By The Department Of Health And Human Services |
Variants of humanized anti carcinoma monoclonal antibody cc49
|
|
JP2002528140A
(ja)
|
1998-11-05 |
2002-09-03 |
ザ ボード オブ トラスティーズ オブ リーランド スタンフォード ジュニア ユニバーシティ |
ヒトｐａｎ−ｈｃｖヒトモノクローナル抗体
|
|
JP2002530081A
(ja)
|
1998-11-18 |
2002-09-17 |
ジェネンテック・インコーポレーテッド |
親抗体より高度な結合親和性を持つ抗体変異体
|
|
US6201104B1
(en)
|
1998-12-04 |
2001-03-13 |
Entremed, Inc. |
Angiogenesis—inhibiting protein binding peptides and proteins and methods of use
|
|
KR20010081089A
(ko)
|
1998-12-21 |
2001-08-25 |
에드워드 에이. 맥더모 2세, 로이드 제이. 오울드 |
절단된 ｖｅｇｆ-ｄ에 대한 항체 및 그것의 이용
|
|
EE05627B1
(et)
|
1998-12-23 |
2013-02-15 |
Pfizer Inc. |
CTLA-4 vastased inimese monoklonaalsed antikehad
|
|
EP1141376A4
(en)
|
1998-12-23 |
2002-03-13 |
Human Genome Sciences |
PEPTIDOGLYCANE RECOGNITION PROTEINS
|
|
US6488930B1
(en)
|
1999-01-15 |
2002-12-03 |
Millennium Pharmaceuticals, Inc. |
Anti-CCR4 antibodies and methods of use therefor
|
|
US6379698B1
(en)
|
1999-04-06 |
2002-04-30 |
Isis Pharmaceuticals, Inc. |
Fusogenic lipids and vesicles
|
|
MXPA01010891A
(es)
|
1999-04-28 |
2002-11-07 |
Univ Texas |
Composiciones y metodos para el tratamiento contra el cancer mediante la inhibicion selectiva del factor de crecimiento endotelial vascular (vegf).
|
|
IL146005A0
(en)
|
1999-05-07 |
2002-07-25 |
Genentech Inc |
Treatment of autoimmune diseases with antagonists which bind to b cell surface markers
|
|
US7534866B2
(en)
|
2005-10-19 |
2009-05-19 |
Ibc Pharmaceuticals, Inc. |
Methods and compositions for generating bioactive assemblies of increased complexity and uses
|
|
US8119101B2
(en)
|
1999-05-10 |
2012-02-21 |
The Ohio State University |
Anti-CD74 immunoconjugates and methods of use
|
|
US7550143B2
(en)
|
2005-04-06 |
2009-06-23 |
Ibc Pharmaceuticals, Inc. |
Methods for generating stably linked complexes composed of homodimers, homotetramers or dimers of dimers and uses
|
|
US7527787B2
(en)
|
2005-10-19 |
2009-05-05 |
Ibc Pharmaceuticals, Inc. |
Multivalent immunoglobulin-based bioactive assemblies
|
|
US7666400B2
(en)
|
2005-04-06 |
2010-02-23 |
Ibc Pharmaceuticals, Inc. |
PEGylation by the dock and lock (DNL) technique
|
|
US7829064B2
(en)
|
1999-05-10 |
2010-11-09 |
Immunomedics, Inc. |
Anti-CD74 immunoconjugates and methods
|
|
US6946129B1
(en)
|
1999-06-08 |
2005-09-20 |
Seattle Genetics, Inc. |
Recombinant anti-CD40 antibody and uses thereof
|
|
DE19926154A1
(de)
|
1999-06-09 |
2000-12-14 |
Ktb Tumorforschungs Gmbh |
Verfahren zur Herstellung einer injizierbaren Arzneimittelzubereitung
|
|
KR20020020730A
(ko)
|
1999-06-09 |
2002-03-15 |
오트리브 데이비스 더블유 |
Ｂ-세포를 표적하는 항체를 이용한 자가면역질환의 면역치료
|
|
US20020002270A1
(en)
|
1999-06-16 |
2002-01-03 |
Raymond P. Zinkowski |
Purified antigen for alzheimer's disease, and methods of obtaining and using same
|
|
US6355481B1
(en)
|
1999-06-18 |
2002-03-12 |
Emory University |
Hybridoma cell line and monoclonal antibody for huntingtin protein
|
|
US6964854B1
(en)
|
1999-07-13 |
2005-11-15 |
Science & Technology Corporation |
Compositions and methods useful for the diagnosis and treatment of heparin induced thrombocytopenia/thrombosis
|
|
US6693176B1
(en)
|
1999-07-23 |
2004-02-17 |
University Of Massachusetts |
Antitumor antibodies, proteins, and uses thereof
|
|
US6376654B1
(en)
|
1999-08-13 |
2002-04-23 |
Molecular Discoveries, Llc |
Myeloma cell and ovarian cancer cell surface glycoproteins, antibodies thereto, and uses thereof
|
|
US6716966B1
(en)
|
1999-08-18 |
2004-04-06 |
Altarex Corp. |
Therapeutic binding agents against MUC-1 antigen and methods for their use
|
|
US6630144B1
(en)
|
1999-08-30 |
2003-10-07 |
The United States Of America As Represented By The Secretary Of The Army |
Monoclonal antibodies to Ebola glycoprotein
|
|
WO2001024763A2
(en)
|
1999-10-01 |
2001-04-12 |
Immunogen, Inc. |
Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
|
|
US6824780B1
(en)
|
1999-10-29 |
2004-11-30 |
Genentech, Inc. |
Anti-tumor antibody compositions and methods of use
|
|
US20030031670A1
(en)
|
1999-11-08 |
2003-02-13 |
Jack R. Wands |
Diagnosis and treatment of malignant neoplasms
|
|
US6835370B2
(en)
|
1999-11-08 |
2004-12-28 |
Rhode Island Hospital |
Diagnosis and treatment of malignant neoplasms
|
|
US6994852B1
(en)
|
1999-11-12 |
2006-02-07 |
Temple University-Of The Commonwealth System Of Higher Education |
Inhibition of angiogenesis by antibodies against high molecular weight kininogen domain 5
|
|
US6994976B1
(en)
|
1999-11-19 |
2006-02-07 |
Tittle Thomas V |
Tr3-specific binding agents and methods for their use
|
|
US6319675B1
(en)
|
1999-11-24 |
2001-11-20 |
Millennium Pharmaceuticals, Inc. |
Methods for detecting and/or identifying agents which bind and/or modulate function of “bonzo” chemokine receptor
|
|
US6530944B2
(en)
|
2000-02-08 |
2003-03-11 |
Rice University |
Optically-active nanoparticles for use in therapeutic and diagnostic methods
|
|
US6835549B2
(en)
|
2000-02-24 |
2004-12-28 |
University Of Medicine & Dentistry Of New Jersey |
Immunoassay method for the diagnosis of gastric intestinal metaplasia associated with gastric carcinoma
|
|
PT1265929E
(pt)
|
2000-03-23 |
2009-10-15 |
Genentech Inc |
Inibidores anti-c2/c2a de activação complementar
|
|
WO2001085203A2
(en)
|
2000-05-11 |
2001-11-15 |
Altarex Corp. |
Therapeutic method and composition utilizing antigen-antibody complexation and presentation by dendritic cells
|
|
MXPA02012106A
(es)
|
2000-06-06 |
2003-06-06 |
Bristol Myers Squibb Co |
Polipeptidos y acidos nucleicos relacionados con b7 empleados para inmunomodulacion.
|
|
AU2001278129A1
(en)
|
2000-07-31 |
2002-02-13 |
The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services |
Specific binding agents for kshv vil-6 that neutralize a biological activity
|
|
US7060802B1
(en)
|
2000-09-18 |
2006-06-13 |
The Trustees Of Columbia University In The City Of New York |
Tumor-associated marker
|
|
US6989241B2
(en)
|
2000-10-02 |
2006-01-24 |
Oklahoma Medical Research Foundation |
Assay for rapid detection of human activated protein C and highly specific monoclonal antibody therefor
|
|
WO2002030985A2
(en)
|
2000-10-10 |
2002-04-18 |
Tanox, Inc. |
Inhibition of complement c5 activation for the treatment and prevention of delayed xenograft or acute vascular rejection
|
|
US20030133972A1
(en)
|
2000-10-11 |
2003-07-17 |
Targesome, Inc. |
Targeted multivalent macromolecules
|
|
US7138496B2
(en)
|
2002-02-08 |
2006-11-21 |
Genetastix Corporation |
Human monoclonal antibodies against human CXCR4
|
|
GB0028361D0
(en)
|
2000-11-21 |
2001-01-03 |
Glaxo Group Ltd |
Method of separating extra chromosomal dna from other cellular components
|
|
MA26040A1
(fr)
|
2001-01-05 |
2004-04-01 |
Pfizer |
Des anticorps pour recepteur i de facteur de croissance insulinique
|
|
US6743898B2
(en)
|
2001-03-15 |
2004-06-01 |
Ochsner Clinic Foundation |
Monoclonal antibodies that suppress B cell growth and/or differentiation
|
|
EP1372741B1
(en)
|
2001-03-30 |
2006-08-09 |
University of Massachusetts |
Morpholino imaging and therapy
|
|
US6824778B2
(en)
|
2001-04-23 |
2004-11-30 |
The United States Of America As Represented By The Secretary Of The Army |
Prophylactic and therapeutic monoclonal antibodies
|
|
US20040175756A1
(en)
|
2001-04-26 |
2004-09-09 |
Avidia Research Institute |
Methods for using combinatorial libraries of monomer domains
|
|
DK1390535T3
(da)
|
2001-04-26 |
2010-12-06 |
Amgen Mountain View Inc |
Kombinatoriske biblioteker af monomer-domæner
|
|
US20050053973A1
(en)
|
2001-04-26 |
2005-03-10 |
Avidia Research Institute |
Novel proteins with targeted binding
|
|
US20050048512A1
(en)
|
2001-04-26 |
2005-03-03 |
Avidia Research Institute |
Combinatorial libraries of monomer domains
|
|
US20050089932A1
(en)
|
2001-04-26 |
2005-04-28 |
Avidia Research Institute |
Novel proteins with targeted binding
|
|
US6962813B2
(en)
|
2001-05-21 |
2005-11-08 |
The Brigham And Women's Hospital, Inc. |
P. aeruginosa mucoid exopolysaccharide specific binding peptides
|
|
NZ513418A
(en)
|
2001-08-07 |
2004-04-30 |
Univ Massey |
Vaccine comprising proteins from mycobacterium paratuberculosis
|
|
US7049060B2
(en)
|
2001-11-05 |
2006-05-23 |
Ortho-Clinical Diagnostics, Inc. |
HCV anti-core monoclonal antibodies
|
|
US6716821B2
(en)
|
2001-12-21 |
2004-04-06 |
Immunogen Inc. |
Cytotoxic agents bearing a reactive polyethylene glycol moiety, cytotoxic conjugates comprising polyethylene glycol linking groups, and methods of making and using the same
|
|
SE0104462D0
(sv)
|
2001-12-29 |
2001-12-29 |
Carlbiotech Ltd As |
Peptide purifcation (Peptidrening)
|
|
KR101033196B1
(ko)
|
2002-02-14 |
2011-05-09 |
이뮤노메딕스, 인코오포레이티드 |
항-ｃｄ20 항체 및 그 융합 단백질 및 이들의 이용방법
|
|
US8287864B2
(en)
|
2002-02-14 |
2012-10-16 |
Immunomedics, Inc. |
Structural variants of antibodies for improved therapeutic characteristics
|
|
US8877901B2
(en)
*
|
2002-12-13 |
2014-11-04 |
Immunomedics, Inc. |
Camptothecin-binding moiety conjugates
|
|
US7591994B2
(en)
|
2002-12-13 |
2009-09-22 |
Immunomedics, Inc. |
Camptothecin-binding moiety conjugates
|
|
US8435529B2
(en)
*
|
2002-06-14 |
2013-05-07 |
Immunomedics, Inc. |
Combining radioimmunotherapy and antibody-drug conjugates for improved cancer therapy
|
|
EP1483295B1
(en)
*
|
2002-03-01 |
2008-12-10 |
Immunomedics, Inc. |
Rs7 antibodies
|
|
ATE477276T1
(de)
|
2002-03-01 |
2010-08-15 |
Immunomedics Inc |
Internalisierung von anti cd74 monoklonalen antikörpern und deren verwendungen
|
|
FR2840532B1
(fr)
|
2002-06-11 |
2005-05-06 |
Ethypharm Sa |
Nanocapsules lipidiques furtives, procede de preparation et utilisation comme vecteur de principes(s) actif(s)
|
|
JP5110768B2
(ja)
|
2002-06-14 |
2012-12-26 |
イミューノメディクス、インコーポレイテッド |
モノクローナル抗体ｐａｍ４ならびに膵臓癌の診断および治療のためのその使用
|
|
US7906118B2
(en)
|
2005-04-06 |
2011-03-15 |
Ibc Pharmaceuticals, Inc. |
Modular method to prepare tetrameric cytokines with improved pharmacokinetics by the dock-and-lock (DNL) technology
|
|
CN1675245B
(zh)
|
2002-06-14 |
2011-01-12 |
免疫医疗公司 |
人源化单克隆抗体hPAM4
|
|
CA2494310A1
(en)
|
2002-08-01 |
2004-02-12 |
Immunomedics, Inc. |
Alpha-fetoprotein immu31 antibodies and fusion proteins and methods of use thereof
|
|
US7541440B2
(en)
|
2002-09-30 |
2009-06-02 |
Immunomedics, Inc. |
Chimeric, human and humanized anti-granulocyte antibodies and methods of use
|
|
WO2004032857A2
(en)
*
|
2002-10-08 |
2004-04-22 |
Immunomedics, Inc. |
Antibody therapy
|
|
US7217797B2
(en)
|
2002-10-15 |
2007-05-15 |
Pdl Biopharma, Inc. |
Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
|
|
US8420086B2
(en)
*
|
2002-12-13 |
2013-04-16 |
Immunomedics, Inc. |
Camptothecin conjugates of anti-CD22 antibodies for treatment of B cell diseases
|
|
JP4959136B2
(ja)
|
2002-12-13 |
2012-06-20 |
イミューノメディクス、インコーポレイテッド |
細胞内で開裂可能な結合を有する免疫接合体
|
|
US7534427B2
(en)
|
2002-12-31 |
2009-05-19 |
Immunomedics, Inc. |
Immunotherapy of B cell malignancies and autoimmune diseases using unconjugated antibodies and conjugated antibodies and antibody combinations and fusion proteins
|
|
US20040202666A1
(en)
|
2003-01-24 |
2004-10-14 |
Immunomedics, Inc. |
Anti-cancer anthracycline drug-antibody conjugates
|
|
CN1745104A
(zh)
|
2003-01-28 |
2006-03-08 |
先灵公司 |
特异于类浆细胞树突状细胞的抗体
|
|
US7172751B2
(en)
|
2003-06-13 |
2007-02-06 |
Immunomedics, Inc. |
D-amino acid peptides
|
|
EP2216342B1
(en)
|
2003-07-31 |
2015-04-22 |
Immunomedics, Inc. |
Anti-CD19 antibodies
|
|
US7902338B2
(en)
|
2003-07-31 |
2011-03-08 |
Immunomedics, Inc. |
Anti-CD19 antibodies
|
|
WO2005014618A2
(en)
|
2003-08-08 |
2005-02-17 |
Immunomedics, Inc. |
Bispecific antibodies for inducing apoptosis of tumor and diseased cells
|
|
US8551480B2
(en)
|
2004-02-13 |
2013-10-08 |
Immunomedics, Inc. |
Compositions and methods of use of immunotoxins comprising ranpirnase (Rap) show potent cytotoxic activity
|
|
US8034352B2
(en)
|
2005-04-06 |
2011-10-11 |
Ibc Pharmaceuticals, Inc. |
Tetrameric cytokines with improved biological activity
|
|
WO2005080586A1
(en)
|
2004-02-13 |
2005-09-01 |
Immunomedics, Inc. |
Fusion proteins containing recombinant cytotoxic rnases
|
|
US8003111B2
(en)
|
2005-04-06 |
2011-08-23 |
Ibc Pharmaceuticals, Inc. |
Dimeric alpha interferon pegylated site-specifically shows enhanced and prolonged efficacy in vivo
|
|
EP3088004B1
(en)
|
2004-09-23 |
2018-03-28 |
Genentech, Inc. |
Cysteine engineered antibodies and conjugates
|
|
EP1807436B1
(en)
|
2004-10-25 |
2014-06-18 |
Intezyne Technologies Inc. |
Heterobifunctional poly(ethylene glycol) and uses thereof
|
|
US7251164B2
(en)
|
2004-11-10 |
2007-07-31 |
Innovative Silicon S.A. |
Circuitry for and method of improving statistical distribution of integrated circuits
|
|
CA2599734C
(en)
|
2005-03-03 |
2014-01-28 |
Immunomedics, Inc. |
Humanized l243 antibodies
|
|
CN101484182B
(zh)
|
2005-04-06 |
2014-06-11 |
Ibc药品公司 |
由同二聚体、同四聚体或二聚体的二聚体组成的稳定连接复合体的生产方法及用途
|
|
US8349332B2
(en)
|
2005-04-06 |
2013-01-08 |
Ibc Pharmaceuticals, Inc. |
Multiple signaling pathways induced by hexavalent, monospecific and bispecific antibodies for enhanced toxicity to B-cell lymphomas and other diseases
|
|
CN101534865A
(zh)
|
2005-10-19 |
2009-09-16 |
Ibc药品公司 |
生物活性装配体的制备方法及其用途
|
|
MX2008013105A
(es)
|
2006-04-19 |
2008-10-27 |
Bionumerik Pharmaceuticals Inc |
Analogo de camptotecina con anillo e "basculante", estable en lactona, novedoso, y metodo para su fabricacion y uso.
|
|
EP2016173A4
(en)
|
2006-05-15 |
2010-06-09 |
Immunomedics Inc |
METHOD AND COMPOSITIONS FOR TREATING HUMAN IMMUNODEFECT VIRUS INFECTIONS WITH CONJUGATED ANTIBODIES OR ANTIBODY FRAGMENTS
|
|
US8267865B2
(en)
|
2007-02-16 |
2012-09-18 |
University Of Rochester |
Sonoelastographic shear velocity imaging using crawling wave excitation
|
|
ITTO20080313A1
(it)
|
2008-04-22 |
2009-10-23 |
Marco Colombatti |
Anticorpo monoclonale isolato o suo frammento legante l'antigene specifico di membrana della prostata, suoi coniugati e suoi usi
|
|
EP2331134A4
(en)
*
|
2008-08-08 |
2014-10-15 |
Immunomedics Inc |
ANTI-PANCREAS CANCER ANTIBODY
|
|
AU2009282830B2
(en)
|
2008-08-20 |
2013-11-28 |
Ibc Pharmaceuticals, Inc. |
Dock-and-lock (DNL) vaccines for cancer therapy
|
|
EP2393512B1
(en)
|
2009-02-05 |
2016-10-26 |
ONCOXX Biotech s.r.l. |
Anti-trop-2 monoclonal antibodies and uses thereof in the treatment and diagnosis of tumors
|
|
EP3903829B1
(en)
|
2009-02-13 |
2023-05-03 |
Immunomedics, Inc. |
Immunoconjugates with an intracellularly-cleavable linkage
|
|
CA2774015A1
(en)
*
|
2009-09-15 |
2011-03-24 |
Cerulean Pharma Inc. |
A cdp-camptothecin conjugate, particle or composition and uses thereof
|
|
WO2011123428A1
(en)
*
|
2010-04-01 |
2011-10-06 |
Immunomedics, Inc. |
Antibody-based depletion of antigen-presenting cells and dendritic cells
|
|
SG185583A1
(en)
*
|
2010-05-17 |
2012-12-28 |
Livtech Inc |
Anti-human trop-2 antibody having antitumor activity in vivo
|
|
WO2011155579A1
(ja)
*
|
2010-06-10 |
2011-12-15 |
北海道公立大学法人札幌医科大学 |
抗Ｔｒｏｐ－２抗体
|
|
ES2596194T3
(es)
|
2011-04-01 |
2017-01-05 |
Wyeth Llc |
Conjugados de anticuerpo-fármaco
|
|
CA2831572C
(en)
|
2011-05-02 |
2019-11-26 |
Immunomedics, Inc. |
Ultrafiltration concentration of allotype selected antibodies for small-volume administration
|
|
CN104053672A
(zh)
|
2011-11-11 |
2014-09-17 |
瑞纳神经科学公司 |
Trop-2特异性抗体及其用途
|
|
US9382329B2
(en)
|
2012-08-14 |
2016-07-05 |
Ibc Pharmaceuticals, Inc. |
Disease therapy by inducing immune response to Trop-2 expressing cells
|
|
US10413539B2
(en)
*
|
2012-12-13 |
2019-09-17 |
Immunomedics, Inc. |
Therapy for metastatic urothelial cancer with the antibody-drug conjugate, sacituzumab govitecan (IMMU-132)
|
|
US10137196B2
(en)
*
|
2012-12-13 |
2018-11-27 |
Immunomedics, Inc. |
Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity
|
|
US9492566B2
(en)
*
|
2012-12-13 |
2016-11-15 |
Immunomedics, Inc. |
Antibody-drug conjugates and uses thereof
|
|
DK2900277T3
(da)
*
|
2012-12-13 |
2022-04-04 |
Immunomedics Inc |
Doser af immunokonjugater af antistoffer og sn-38 til forbedret effektivitet og reduceret toksicitet
|
|
US10195175B2
(en)
*
|
2015-06-25 |
2019-02-05 |
Immunomedics, Inc. |
Synergistic effect of anti-Trop-2 antibody-drug conjugate in combination therapy for triple-negative breast cancer when used with microtubule inhibitors or PARP inhibitors
|
|
US10669338B2
(en)
*
|
2016-06-17 |
2020-06-02 |
Immunomedics, Inc. |
Anti-PD-1 checkpoint inhibitor antibodies that block binding of PD-L1 to PD-1
|