JP2016128474A5 - - Google Patents
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- JP2016128474A5 JP2016128474A5 JP2016013547A JP2016013547A JP2016128474A5 JP 2016128474 A5 JP2016128474 A5 JP 2016128474A5 JP 2016013547 A JP2016013547 A JP 2016013547A JP 2016013547 A JP2016013547 A JP 2016013547A JP 2016128474 A5 JP2016128474 A5 JP 2016128474A5
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- 239000008194 pharmaceutical composition Substances 0.000 claims 18
- 239000012634 fragment Substances 0.000 claims 10
- 125000003275 alpha amino acid group Chemical group 0.000 claims 7
- 239000000427 antigen Substances 0.000 claims 6
- 102000036639 antigens Human genes 0.000 claims 6
- 108091007433 antigens Proteins 0.000 claims 6
- 238000011275 oncology therapy Methods 0.000 claims 4
- 238000011282 treatment Methods 0.000 claims 4
- 241001465754 Metazoa Species 0.000 claims 3
- 208000023275 Autoimmune disease Diseases 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 229920001184 polypeptide Polymers 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 206010009944 Colon cancer Diseases 0.000 claims 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 1
- 102100034384 Plexin-B1 Human genes 0.000 claims 1
- 101710100559 Plexin-B1 Proteins 0.000 claims 1
- 206010060862 Prostate cancer Diseases 0.000 claims 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 1
- 230000001093 anti-cancer Effects 0.000 claims 1
- 238000009175 antibody therapy Methods 0.000 claims 1
- 206010003246 arthritis Diseases 0.000 claims 1
- 230000001363 autoimmune Effects 0.000 claims 1
- 208000037979 autoimmune inflammatory disease Diseases 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 238000009566 cancer vaccine Methods 0.000 claims 1
- 238000002512 chemotherapy Methods 0.000 claims 1
- 208000029742 colonic neoplasm Diseases 0.000 claims 1
- 238000010494 dissociation reaction Methods 0.000 claims 1
- 230000005593 dissociations Effects 0.000 claims 1
- 201000010536 head and neck cancer Diseases 0.000 claims 1
- 208000014829 head and neck neoplasm Diseases 0.000 claims 1
- 238000009169 immunotherapy Methods 0.000 claims 1
- 210000004969 inflammatory cell Anatomy 0.000 claims 1
- 208000027866 inflammatory disease Diseases 0.000 claims 1
- 201000005202 lung cancer Diseases 0.000 claims 1
- 208000020816 lung neoplasm Diseases 0.000 claims 1
- 208000037819 metastatic cancer Diseases 0.000 claims 1
- 208000011575 metastatic malignant neoplasm Diseases 0.000 claims 1
- 201000006417 multiple sclerosis Diseases 0.000 claims 1
- 238000001959 radiotherapy Methods 0.000 claims 1
- 150000003384 small molecules Chemical class 0.000 claims 1
- 210000004881 tumor cell Anatomy 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17682609P | 2009-05-08 | 2009-05-08 | |
| US61/176,826 | 2009-05-08 | ||
| US32521310P | 2010-04-16 | 2010-04-16 | |
| US61/325,213 | 2010-04-16 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012510026A Division JP6059013B2 (ja) | 2009-05-08 | 2010-05-07 | 抗ｃｄ１００抗体およびこれを使用するための方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017026605A Division JP2017113017A (ja) | 2009-05-08 | 2017-02-16 | 抗ｃｄ１００抗体およびこれを使用するための方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016128474A JP2016128474A (ja) | 2016-07-14 |
| JP2016128474A5 true JP2016128474A5 (enExample) | 2016-12-01 |
| JP6096946B2 JP6096946B2 (ja) | 2017-03-15 |
Family
ID=43050912
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012510026A Active JP6059013B2 (ja) | 2009-05-08 | 2010-05-07 | 抗ｃｄ１００抗体およびこれを使用するための方法 |
| JP2016013547A Active JP6096946B2 (ja) | 2009-05-08 | 2016-01-27 | 抗ｃｄ１００抗体およびこれを使用するための方法 |
| JP2017026605A Pending JP2017113017A (ja) | 2009-05-08 | 2017-02-16 | 抗ｃｄ１００抗体およびこれを使用するための方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012510026A Active JP6059013B2 (ja) | 2009-05-08 | 2010-05-07 | 抗ｃｄ１００抗体およびこれを使用するための方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017026605A Pending JP2017113017A (ja) | 2009-05-08 | 2017-02-16 | 抗ｃｄ１００抗体およびこれを使用するための方法 |
Country Status (19)
| Country | Link |
|---|---|
| US (6) | US8496938B2 (enExample) |
| EP (2) | EP3320920A1 (enExample) |
| JP (3) | JP6059013B2 (enExample) |
| KR (2) | KR20170080705A (enExample) |
| CN (2) | CN102458468B (enExample) |
| AU (2) | AU2010245668B2 (enExample) |
| CA (1) | CA2760890C (enExample) |
| DK (1) | DK2427212T3 (enExample) |
| EA (1) | EA025245B1 (enExample) |
| ES (1) | ES2647823T3 (enExample) |
| IL (3) | IL216002A (enExample) |
| MX (2) | MX2011011718A (enExample) |
| NO (1) | NO2427212T3 (enExample) |
| NZ (2) | NZ596136A (enExample) |
| PL (1) | PL2427212T3 (enExample) |
| PT (1) | PT2427212T (enExample) |
| SG (1) | SG175417A1 (enExample) |
| WO (1) | WO2010129917A2 (enExample) |
| ZA (1) | ZA201108162B (enExample) |
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| US10494440B2 (en) * | 2012-05-11 | 2019-12-03 | Vaccinex, Inc. | Use of semaphorin-4D binding molecules to promote neurogenesis following stroke |
| US10626163B2 (en) | 2013-01-25 | 2020-04-21 | Brandeis University | Methods of modulating GABAergic inhibitory synapse formation and function |
| KR20160006168A (ko) * | 2013-03-18 | 2016-01-18 | 바이오서오엑스 프로덕스 비.브이. | 인간화 항-cd134(ox40) 항체 및 이의 용도 |
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| BR112018071686A2 (pt) | 2016-04-22 | 2019-02-19 | Vaccinex, Inc. | exibição de proteínas integrais de membrana em vírions extracelulares envelopados de poxvírus |
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| AU2019243154A1 (en) | 2018-03-28 | 2020-10-01 | Cero Therapeutics, Inc. | Cellular immunotherapy compositions and uses thereof |
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| CN110713537B (zh) * | 2018-07-13 | 2023-04-21 | 江苏怀瑜药业有限公司 | 一种sema4d抗体及其制备方法和应用 |
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| CA3142777A1 (en) | 2019-06-21 | 2020-12-24 | Vaccinex, Inc. | Combination therapy with semaphorin-4d blockade (sema4d) and dc1 therapy |
| WO2021013061A1 (zh) * | 2019-07-19 | 2021-01-28 | 神州细胞工程有限公司 | 一种人源化抗vegfr2抗体及其应用 |
| US20210032322A1 (en) * | 2019-08-01 | 2021-02-04 | Vaccinex, Inc. | Combined inhibition of semaphorin-4d and tgf-beta and compositions therefor |
| CN117597360A (zh) | 2020-06-25 | 2024-02-23 | 瓦西尼斯公司 | 脑信号蛋白-4d结合分子在rett综合征治疗中的应用 |
| CN113583122B (zh) * | 2021-07-29 | 2023-08-29 | 武汉华美生物工程有限公司 | 抗人sema4d抗体及其制备方法和应用 |
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| EP4426745A2 (en) * | 2021-11-03 | 2024-09-11 | Rutgers, the State University of New Jersey | Antibody-drug conjugates against the receptor tyrosine kinase epha5 |
| US20230331863A1 (en) | 2022-02-13 | 2023-10-19 | Vaccinex, Inc. | Combination therapy with semaphorin-4d blockade and htt-lowering agent for treatment of huntington's disease |
| CN117866091A (zh) * | 2022-10-12 | 2024-04-12 | 三优生物医药(上海)有限公司 | 抗cd100抗体及其用途 |
| CN118108841A (zh) * | 2022-11-30 | 2024-05-31 | 三优生物医药(上海)有限公司 | 抗cd100抗体及其用途 |
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