JP2016108346A5 - - Google Patents

Download PDF

Info

Publication number
JP2016108346A5
JP2016108346A5 JP2016054145A JP2016054145A JP2016108346A5 JP 2016108346 A5 JP2016108346 A5 JP 2016108346A5 JP 2016054145 A JP2016054145 A JP 2016054145A JP 2016054145 A JP2016054145 A JP 2016054145A JP 2016108346 A5 JP2016108346 A5 JP 2016108346A5
Authority
JP
Japan
Prior art keywords
composition according
pimobendan
pharmaceutical composition
carrier matrix
weight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2016054145A
Other languages
English (en)
Japanese (ja)
Other versions
JP6506711B2 (ja
JP2016108346A (ja
Filing date
Publication date
Application filed filed Critical
Publication of JP2016108346A publication Critical patent/JP2016108346A/ja
Publication of JP2016108346A5 publication Critical patent/JP2016108346A5/ja
Application granted granted Critical
Publication of JP6506711B2 publication Critical patent/JP6506711B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2016054145A 2013-12-04 2016-03-17 ピモベンダンの改善された医薬組成物 Active JP6506711B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HUP1300702 2013-12-04
HUP1300702 2013-12-04

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2015554220A Division JP5905999B2 (ja) 2013-12-04 2014-12-01 ピモベンダンの改善された医薬組成物

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019066575A Division JP2019123737A (ja) 2013-12-04 2019-03-29 ピモベンダンの改善された医薬組成物

Publications (3)

Publication Number Publication Date
JP2016108346A JP2016108346A (ja) 2016-06-20
JP2016108346A5 true JP2016108346A5 (cg-RX-API-DMAC7.html) 2018-01-18
JP6506711B2 JP6506711B2 (ja) 2019-04-24

Family

ID=89708176

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2015554220A Active JP5905999B2 (ja) 2013-12-04 2014-12-01 ピモベンダンの改善された医薬組成物
JP2016054145A Active JP6506711B2 (ja) 2013-12-04 2016-03-17 ピモベンダンの改善された医薬組成物
JP2019066575A Pending JP2019123737A (ja) 2013-12-04 2019-03-29 ピモベンダンの改善された医薬組成物

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2015554220A Active JP5905999B2 (ja) 2013-12-04 2014-12-01 ピモベンダンの改善された医薬組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2019066575A Pending JP2019123737A (ja) 2013-12-04 2019-03-29 ピモベンダンの改善された医薬組成物

Country Status (16)

Country Link
US (5) US10172804B2 (cg-RX-API-DMAC7.html)
EP (2) EP2925305B1 (cg-RX-API-DMAC7.html)
JP (3) JP5905999B2 (cg-RX-API-DMAC7.html)
KR (1) KR102308973B1 (cg-RX-API-DMAC7.html)
CN (2) CN110721164B (cg-RX-API-DMAC7.html)
AU (2) AU2014359427B2 (cg-RX-API-DMAC7.html)
BR (2) BR112016011111B1 (cg-RX-API-DMAC7.html)
CA (2) CA2930033C (cg-RX-API-DMAC7.html)
DK (2) DK3106150T3 (cg-RX-API-DMAC7.html)
EA (2) EA034054B1 (cg-RX-API-DMAC7.html)
ES (2) ES2593210T3 (cg-RX-API-DMAC7.html)
HU (2) HUE032347T2 (cg-RX-API-DMAC7.html)
MX (1) MX375936B (cg-RX-API-DMAC7.html)
PL (2) PL2925305T3 (cg-RX-API-DMAC7.html)
WO (1) WO2015082389A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201602447B (cg-RX-API-DMAC7.html)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8980894B2 (en) 2004-03-25 2015-03-17 Boehringer Ingelheim Vetmedica Gmbh Use of PDE III inhibitors for the treatment of asymptomatic (occult) heart failure
EP1579862A1 (en) 2004-03-25 2005-09-28 Boehringer Ingelheim Vetmedica Gmbh Use of PDE III inhibitors for the reduction of heart size in mammals suffering from heart failure
EP1920785A1 (en) 2006-11-07 2008-05-14 Boehringer Ingelheim Vetmedica Gmbh Liquid preparation comprising a complex of pimobendan and cyclodextrin
EP2825159B1 (en) * 2012-03-15 2022-06-22 Boehringer Ingelheim Vetmedica GmbH Pharmaceutical tablet formulation for the veterinary medical sector, method of production and use thereof
PL3021832T3 (pl) 2013-07-19 2021-08-23 Boehringer Ingelheim Vetmedica Gmbh Konserwowana ciekła wodna kompozycja farmaceutyczna zawierająca eteryfikowane pochodne cyklodekstryny
AU2014359427B2 (en) 2013-12-04 2017-04-20 Boehringer Ingelheim Vetmedica Gmbh Improved pharmaceutical compositions of pimobendan
US10537570B2 (en) 2016-04-06 2020-01-21 Boehringer Ingelheim Vetmedica Gmbh Use of pimobendan for the reduction of heart size and/or the delay of onset of clinical symptoms in patients with asymptomatic heart failure due to mitral valve disease
EP3257574A1 (en) * 2016-06-15 2017-12-20 Clariant International Ltd Method for producing a particle-shaped material
BR112021016480A2 (pt) 2019-02-20 2021-10-13 Zoetis Services Llc Formulações palatáveis
JP2022554144A (ja) * 2019-10-23 2022-12-28 ピードモント アニマル ヘルス インコーポレイテッド ピモベンダン製剤およびその使用方法
RU2762989C1 (ru) * 2020-09-28 2021-12-24 федеральное государственное автономное образовательное учреждение высшего образования "Российский университет дружбы народов" (РУДН) Способ лечения собак, больных дилатационной кардиомиопатией, осложненной застойной сердечной недостаточностью
WO2022073954A1 (en) 2020-10-08 2022-04-14 Boehringer Ingelheim Vetmedica Gmbh Use of pimobendan in the anaesthesia of non-human mammals
CN113804793B (zh) * 2021-09-24 2023-10-31 青岛欧博方医药科技有限公司 匹莫苯丹软咀嚼剂型的杂质检测方法
AR131339A1 (es) 2022-12-15 2025-03-12 Boehringer Ingelheim Vetmedica Gmbh Dispersiones sólidas que comprenden pimobendan amorfo y uno o más polímeros estabilizantes
WO2024240632A1 (en) 2023-05-24 2024-11-28 Boehringer Ingelheim Vetmedica Gmbh Combination treatment and/or prevention of cardiac diseases in non-human mammals comprising one or more sglt-2 inhibitors and pimobendan and/or telmisartan

Family Cites Families (151)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1045031A (en) 1963-04-30 1966-10-05 Iwao Kawakami Dentifrice
US3574859A (en) 1968-07-05 1971-04-13 Carl M Kosti Process for the treatment of hypertrophied gums
US3822349A (en) 1969-06-02 1974-07-02 C Kosti Vasoconstrictor-antihistamine composition for the treatment of hypertrophied oral tissue
CA950833A (en) 1971-02-02 1974-07-09 Carl M. Kosti Composition for the treatment of hypertrophied oral tissue
GB1338169A (en) 1971-03-09 1973-11-21 Smith Kline French Lab Ureas thioureas and guanidines
US3832460A (en) 1971-03-19 1974-08-27 C Kosti Anesthetic-vasoconstrictor-antihistamine composition for the treatment of hypertrophied oral tissue
US3839522A (en) 1971-08-02 1974-10-01 Batley Janss Enterprises Process for the manufacture of dog bedding
CH630808A5 (en) 1976-05-08 1982-07-15 Uscio Heinz D Process for aromatising pharmaceutical preparations for veterinary medicine
GB1565966A (en) 1976-08-04 1980-04-23 Allen & Hanburys Ltd Aminoalkyl furan derivatives
ES8101067A1 (es) 1978-08-25 1980-12-01 Thomae Gmbh Dr K Procedimiento para la preparacion de nuevos bencimidazoles sustituidos en posicion 5 o 6 con un anillo de piridazinona
DE2841668A1 (de) 1978-09-25 1980-04-10 Bayer Ag Medikiertes tierfutter auf basis lebermehl
US4256743A (en) 1979-02-22 1981-03-17 President And Fellows Of Harvard College Inhibition of bone resorption with H1 -blocking antihistamines
JPS6056143B2 (ja) 1979-08-02 1985-12-09 山之内製薬株式会社 アミジン誘導体ならびにその製造法
US4293557A (en) 1979-07-03 1981-10-06 Teikoku Hormone Mfg. Co., Ltd. Antiulcer phenoxypropylamine derivatives
US4375547A (en) 1980-10-02 1983-03-01 Eli Lilly And Company N-Methyl-N'-2-([(2-dimethylaminomethyl)-4-thiazolyl]methylthio)ethyl 2-nitro-1,1-ethenediamine
IT1209431B (it) 1980-11-28 1989-07-16 Angeli Inst Spa Imidazolilfenil amidine, processi per la loro preparazione e loro impiego farmaceutico, ed intermedi di preparazione.
DE3124090A1 (de) 1981-06-19 1983-01-05 Dr. Karl Thomae Gmbh, 7950 Biberach Neue orale dipyridamolformen
US4704284A (en) 1982-08-12 1987-11-03 Pfizer Inc. Long-acting matrix tablet formulations
DE3237575A1 (de) 1982-10-09 1984-04-12 Dr. Karl Thomae Gmbh, 7950 Biberach Neue orale mopidamolformen
GB8313217D0 (en) 1983-05-13 1983-06-22 Glaxo Group Ltd Pharmaceutical compositions
JPS59222406A (ja) 1983-06-01 1984-12-14 Teijin Ltd 歯周疾患治療用製剤及びその製造法
US4732915A (en) 1983-11-02 1988-03-22 Alza Corporation Process for increasing solubility of drug
DE3346123A1 (de) 1983-12-21 1985-06-27 Janssen Pharmaceutica, N.V., Beerse Pharmazeutische praeparate von in wasser schwerloeslichen oder instabilen arzneistoffen und verfahren zu ihrer herstellung
GB8400863D0 (en) 1984-01-13 1984-02-15 Smith Kline French Lab Chemical compounds
US6407079B1 (en) 1985-07-03 2002-06-18 Janssen Pharmaceutica N.V. Pharmaceutical compositions containing drugs which are instable or sparingly soluble in water and methods for their preparation
PT83530B (pt) 1985-10-17 1989-05-31 Smith Kline French Lab Processo de preparacao de derivados da piridona, em especial derivados fenilicos
IE63321B1 (en) 1986-02-03 1995-04-05 Elan Corp Plc Drug delivery system
JPS62223112A (ja) 1986-03-25 1987-10-01 Rooto Seiyaku Kk 歯周病治療剤
JPH0759496B2 (ja) 1986-03-25 1995-06-28 ロ−ト製薬株式会社 歯周病治療剤
IT1204901B (it) 1986-06-25 1989-03-10 Iscofar Sas Composizioni contenenti acido usnico o suoi derivati atte all'impiego nel trattamento della carie dentaria
US4868182A (en) 1986-11-05 1989-09-19 Merrell Dow Pharmaceuticals Inc. Enhancement of prazosin
ZA878182B (en) 1986-11-05 1988-05-02 Merrell Dow Pharmaceuticals Inc. Enhancement of prazosin
NL193682C (nl) 1987-05-14 2000-07-04 Glaxo Group Ltd Beklede cefuroximaxetilsamenstelling.
DE3728244A1 (de) 1987-08-25 1989-03-09 Thomae Gmbh Dr K Neue (-)-benzimidazole, deren herstellung und diese verbindungen enthaltende arzneimittel
EP0306846A3 (de) 1987-09-11 1990-05-02 Dr. Karl Thomae GmbH Neue synergistische Kombination bestehend aus einem Phosphodiesterase-Hemmer und einem Thromboxan-A2-Antagonisten und deren Verwendung bzw. Herstellung
SE8704436D0 (sv) 1987-11-13 1987-11-13 Pm Konsult Handelsbolag Anvendning av antisekretoriska substanser for nya indikationer
US4851226A (en) 1987-11-16 1989-07-25 Mcneil Consumer Products Company Chewable medicament tablet containing means for taste masking
US5002935A (en) 1987-12-30 1991-03-26 University Of Florida Improvements in redox systems for brain-targeted drug delivery
DE3804490A1 (de) 1988-02-12 1989-08-24 Heumann Pharma Gmbh & Co Substituierte 6-phenyldihydro-3(2h)-pyridazinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3805635A1 (de) 1988-02-24 1989-09-07 Thomae Gmbh Dr K Verwendung von benzimidazolen zur herstellung eines arzneimittels mit antiischaemischen wirkungen am herzen und dessen kombinationen mit ss-blockern oder bradycardica
DE68906942T3 (de) 1988-03-29 1999-05-12 University Of Florida, Gainesville, Fla. Pharmazeutische Zusammensetzungen für die parenterale Anwendung.
IE62095B1 (en) 1988-03-29 1994-12-14 Univ Florida Pharmaceutical formulations for parenteral use
EP0349657A1 (en) 1988-06-06 1990-01-10 Carl Richard Thornfeldt Manufacture of a medicament for the treatment of teething and colic
GB8824458D0 (en) 1988-10-19 1988-11-23 Orion Yhtymae Oy Substituted pyridazinones
GB8903130D0 (en) 1989-02-11 1989-03-30 Orion Yhtymae Oy Substituted pyridazinones
JP2916689B2 (ja) 1989-11-16 1999-07-05 株式会社資生堂 化粧料
US5364646A (en) 1990-01-10 1994-11-15 Dr. Karl Thomae Gmbh Oral pharmaceutical forms of pimobendan
DE4001622A1 (de) * 1990-01-20 1991-07-25 Thomae Gmbh Dr K Orale arzneimittelformen von pimobendan
DE4001623A1 (de) 1990-01-20 1991-07-25 Thomae Gmbh Dr K Verwendung von benzimidazolen zur herstellung eines zur behandlung von akuten und chronischen obstruktiven atemwegserkrankungen geeigneten arzneimittels
US5188836A (en) 1990-07-27 1993-02-23 Warner-Lambert Company Sustained release formulations
JPH0489428A (ja) 1990-07-30 1992-03-23 Kao Corp 多形核白血球活性化剤
GB2251615B (en) 1991-01-03 1995-02-08 Orion Yhtymae Oy (-)-[[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]hydrazono]pro panedinitrile
JPH0570612A (ja) 1991-09-12 1993-03-23 Toyobo Co Ltd 二軸配向ポリエステルフイルム
US5571533A (en) 1992-02-07 1996-11-05 Recordati, S.A., Chemical And Pharmaceutical Company Controlled-release mucoadhesive pharmaceutical composition for the oral administration of furosemide
US5472954A (en) 1992-07-14 1995-12-05 Cyclops H.F. Cyclodextrin complexation
JPH10501211A (ja) 1994-05-20 1998-02-03 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 飼育動物用のチュワブル・フルベンダゾール錠剤
GB9711643D0 (en) 1997-06-05 1997-07-30 Janssen Pharmaceutica Nv Glass thermoplastic systems
US20030059471A1 (en) * 1997-12-15 2003-03-27 Compton Bruce Jon Oral delivery formulation
JPH11228302A (ja) 1998-02-18 1999-08-24 Taisho Technos Co Ltd 抗菌防黴組成物
US6476078B2 (en) 1999-08-11 2002-11-05 Sepracor, Inc. Methods of using sibutramine metabolites in combination with a phosphodiesterase inhibitor to treat sexual dysfunction
US20020127205A1 (en) 1998-08-31 2002-09-12 Albert Edge Cells expressing immunoregulatory molecules and uses therefor
US20040152664A1 (en) 1998-09-02 2004-08-05 Allergan, Inc. Prednisolone compositions
AU757896B2 (en) 1998-09-02 2003-03-13 Allergan, Inc. Preserved cyclodextrin-containing compositions
DE69823240T2 (de) 1998-10-23 2005-04-28 Toray Industries, Inc. Immunmodulierende arzneimittelzusammenstellung
FR2790668B1 (fr) 1999-03-12 2002-07-26 D B F Granules contenant une substance vegetale et leur procede de preparation
ATE318585T1 (de) 1999-05-17 2006-03-15 D B F Pflanzenmaterial enthaltendes granulat und verfahren zur herstellung
FR2793688B1 (fr) * 1999-05-21 2003-06-13 Ethypharm Lab Prod Ethiques Microgranules gastroproteges, procede d'obtention et preparations pharmaceutiques
US6369087B1 (en) 1999-08-26 2002-04-09 Robert R. Whittle Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
GB2356346A (en) 1999-11-19 2001-05-23 Mars Uk Ltd Food product for oral delivery of a pharmaceutical agent to a non-human animal comprising encapsulated particles of said agent distributed within the product
CN1416341B (zh) 2000-02-04 2010-05-05 武田药品工业株式会社 稳定的乳液组合物
PT1260215E (pt) 2000-03-01 2009-09-03 Eisai R&D Man Co Ltd Comprimido de desintegração rápida que contém poli(álcool vinílico)
JP5026630B2 (ja) 2000-03-31 2012-09-12 小林製薬株式会社 造粒粉体及びその製造方法及び圧縮成形固形物
AU2001271435A1 (en) 2000-06-21 2002-01-02 Bristol-Myers Squibb Pharma Company Vitronectin receptor antagonist pharmaceuticals
PT1913939T (pt) 2000-06-27 2017-07-19 Vectura Ltd Formulações para utilização em dispositivos inalatórios
US6620439B1 (en) 2000-10-03 2003-09-16 Atul M. Mehta Chrono delivery formulations and method of use thereof
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
AU2001225816B2 (en) 2000-12-18 2005-10-13 Novartis Ag Therapeutic combination of amlodipine and benazepril
EP1247456A3 (en) 2001-02-28 2003-12-10 Pfizer Products Inc. Palatable pharmaceutical compositions for companion animals
CA2438272A1 (en) 2001-03-02 2002-10-10 John Macor Compounds useful as modulators of melanocortin receptors and pharmaceutical compositions comprising same
US20040214797A1 (en) 2001-05-07 2004-10-28 Allergan, Inc. Preserved pharmaceutical compositions comprising cyclodextrins
JP2004536614A (ja) 2001-08-01 2004-12-09 ユニバーシティ オブ ユタ Ｐｄｅ３環状ヌクレオチド・ホスホジエステラーゼのアイソフォーム選択的な阻害剤および活性化剤
US6669955B2 (en) 2001-08-28 2003-12-30 Longwood Pharmaceutical Research, Inc. Combination dosage form containing individual dosage units of a cholesterol-lowering agent, an inhibitor of the renin-angiotensin system, and aspirin
WO2003033025A2 (en) 2001-10-18 2003-04-24 Decode Genetics Ehf Cyclodextrin complexes
TW200303749A (en) 2002-02-22 2003-09-16 Pharmacia Corp Ophthalmic antibiotic drug formulations containing a cyclodextrin compound and cetyl pyridinium chloride
US20030190343A1 (en) 2002-03-05 2003-10-09 Pfizer Inc. Palatable pharmaceutical compositions for companion animals
DE10209982A1 (de) 2002-03-07 2003-09-25 Boehringer Ingelheim Pharma Oral zu applizierende Darreichungsform für schwerlösliche basische Wirkstoffe
CO5400144A1 (es) 2002-03-11 2004-05-31 Novartis Ag Compuestos organicos
TW200306799A (en) 2002-05-17 2003-12-01 Novartis Ag Combination of organic compounds
PL374198A1 (en) 2002-05-23 2005-10-03 Pfizer Inc. Novel combination
SI21223A (sl) 2002-06-19 2003-12-31 Krka, Tovarna Zdravil, D.D., Novo Mesto Farmacevtska formulacija s stabiliziranim amorfnim donepezilijevim kloridom
DE10228049A1 (de) 2002-06-24 2004-01-15 Merck Patent Gmbh Flüssige Zubereitung enthaltend Oligopeptide
US20040037869A1 (en) 2002-08-16 2004-02-26 Douglas Cleverly Non-animal product containing veterinary formulations
PL376405A1 (en) 2002-10-07 2005-12-27 Artesian Therapeutics, Inc. Dihydropyridine compounds having simultaneous ability to block l-type calcium channels and to inhibit phosphodiesterase type 3 activity
US7544674B2 (en) 2002-10-25 2009-06-09 Galderma S.A. Topical skin care composition
WO2004050657A2 (en) 2002-11-27 2004-06-17 Artesian Therapeutics, Inc. COMPOUNDS WITH MIXED PDE-INHIBITORY AND β-ADRENERGIC ANTAGONIST OR PARTIAL AGONIST ACTIVITY FOR TREATMENT OF HEART FAILURE
JP2006513238A (ja) * 2002-12-19 2006-04-20 ファルマシア・コーポレーション 吸湿性薬物を含む非‐吸湿性製剤
EP1575923A2 (en) 2002-12-23 2005-09-21 Artesian Therapeutics, Inc. CARDIOTONIC COMPOUNDS WITH INHIBITORY ACTIVITY AGAINST &bgr;-ADRENERGIC RECEPTORS AND PHOSPHODIESTERASE
US20050085446A1 (en) 2003-04-14 2005-04-21 Babu M.K. M. Fluoroquinolone formulations and methods of making and using the same
WO2005035505A2 (en) 2003-09-30 2005-04-21 Artesian Therapeutics, Inc. Compounds with phosphodiesterase inhibiting and calcium channel blocking activities
LT1713504T (lt) 2004-01-30 2017-09-11 Zoetis Services Llc Antimikrobinis konservantas, skirtas multi-dozinėms kompozicijoms, panaudojant beta-ciklodekstrinus, skirtas skystoms vaisto formoms
DE102004011512B4 (de) 2004-03-08 2022-01-13 Boehringer Ingelheim Vetmedica Gmbh Pharmazeutische Zubereitung enthaltend Pimobendan
EP1579862A1 (en) 2004-03-25 2005-09-28 Boehringer Ingelheim Vetmedica Gmbh Use of PDE III inhibitors for the reduction of heart size in mammals suffering from heart failure
US8980894B2 (en) 2004-03-25 2015-03-17 Boehringer Ingelheim Vetmedica Gmbh Use of PDE III inhibitors for the treatment of asymptomatic (occult) heart failure
JP2005281283A (ja) 2004-03-31 2005-10-13 Akira Matsumori ベンズイミダゾール系薬剤の併用医薬
AU2005249372A1 (en) 2004-05-06 2005-12-15 Cydex Pharmaceuticals, Inc. Taste-masked formulations containing sertraline and sulfoalkyl ether cyclodextrin
FI20040675A0 (fi) 2004-05-12 2004-05-12 Orion Corp Menetelmä sydämen hypertrofian hoitoon ja estoon
US20090181083A1 (en) 2004-06-28 2009-07-16 Lifebycle Pharmas A/S Porous tablets as carriers for liquid formulations
NZ534939A (en) 2004-08-26 2007-04-27 Bomac Research Ltd Injectable formulation comprising an anthelmintic compound with complexing compound for improved solubility
EP1830852A2 (en) 2004-11-30 2007-09-12 Artesian Therapeutics, Inc. Compounds with mixed pde-inhibitory and beta-adrenergic antagonist or partial agonist activity for treatment of heart failure
WO2006060122A2 (en) 2004-11-30 2006-06-08 Artesian Therapeutics, Inc. Cardiotonic compounds with inhibitory activity against beta-adrenergic receptors and phosphodiesterase
CN1702243A (zh) 2005-05-31 2005-11-30 刘坚雄 无壁板框架结构装配组合式房屋建筑及其建造方法
US20090036406A1 (en) 2005-06-13 2009-02-05 Takeda Pharmaceutical Company Limited Injection
WO2007038796A1 (en) * 2005-09-29 2007-04-05 Repros Therapeutics Inc. Formulations with improved bioavailability, comprising a steroid derivative and a polyglycolysed glyceride
FR2891459B1 (fr) 2005-09-30 2007-12-28 Flamel Technologies Sa Microparticules a liberation modifiee d'au moins un principe actif et forme galenique orale en comprenant
PL1951227T3 (pl) 2005-11-14 2017-09-29 Boehringer Ingelheim Vetmedica Gmbh Zastosowania pimobendanu do leczenia bezobjawowej(utajonej) niewydolności serca
ES2276627B1 (es) 2005-12-02 2008-04-16 Bsh Electrodomesticos España, S.A. Tambor de lavadora.
JP4572300B2 (ja) * 2006-01-19 2010-11-04 トーアエイヨー株式会社 ピモベンダン経口投与製剤
JP2008534681A (ja) 2006-02-09 2008-08-28 テバ ファーマシューティカル インダストリーズ リミティド ジピリダモール持続放出製剤及びそれを調製のための方法
CA2647533A1 (en) 2006-03-28 2007-10-04 Javelin Pharmaceuticals, Inc. Formulations of low dose non-steroidal anti-inflammatory drugs and beta-cyclodextrin
PE20080697A1 (es) 2006-05-03 2008-08-05 Boehringer Ingelheim Int Derivados de benzonitrilo sustituidos con glucopiranosilo, composiciones farmaceuticas que contienen compuestos de este tipo, su uso y procedimiento para su fabricacion
EP1920785A1 (en) * 2006-11-07 2008-05-14 Boehringer Ingelheim Vetmedica Gmbh Liquid preparation comprising a complex of pimobendan and cyclodextrin
FR2917975B1 (fr) 2007-06-26 2009-10-16 Ceva Sante Animale Sa Compositions et traitement de l'insuffisance cardiaque chez les animaux mammiferes non humains
JP5227569B2 (ja) 2007-11-09 2013-07-03 東京インキ株式会社 微粒子乾式コーティング製剤
EP2057982A1 (en) 2007-11-09 2009-05-13 Archimedes Development Limited Intranasal compositions
EP2106786A1 (de) 2008-04-04 2009-10-07 Roewer, Norbert, Univ.-Prof. Dr. med. Pharmazeutische Zubereitung mit permethyliertem Cyclodextrin
FR2934156B1 (fr) 2008-07-23 2010-09-24 Virbac Medicament appetissant a administration orale sous forme solide
WO2010055119A2 (en) 2008-11-17 2010-05-20 Novartis Ag Pharmaceutical composition comprising pimobendan
CA2744505A1 (en) 2008-11-25 2010-06-03 Boehringer Ingelheim Vetmedica Gmbh Phosphodiesterase type iii (pde iii) inhibitors or ca2+-sensitizing agents for the treatment of hypertrophic cardiomyopathy
WO2010078429A1 (en) 2008-12-30 2010-07-08 Impax Laboratories, Inc. Pharmaceutical dosage forms and methods of manufacturing same
GB0912646D0 (en) * 2009-07-21 2009-08-26 Jagotec Ag Improvements in or relating to organic compounds
US8586092B2 (en) 2009-08-31 2013-11-19 Xi'an Libang Pharmaceutical Technology Co., Ltd. Fulvestrant nanosphere/microsphere and preparative method and use thereof
CN102647978A (zh) 2009-10-07 2012-08-22 力奇制药公司 包含溶解性差的活性成分和高支化聚合物的药物组合物
NL1037569C2 (en) 2009-12-18 2011-06-21 Eurovet Animal Health B V Crystalline pimobendan, process for the preparation thereof, pharmaceutical composition and use.
EP2338480A1 (en) 2009-12-22 2011-06-29 LEK Pharmaceuticals d.d. Coating of particles comprising a pharmaceutically active ingredient with a carbonate salt or phosphate salt
EP2380604A1 (en) 2010-04-19 2011-10-26 InnoRa Gmbh Improved coating formulations for scoring or cutting balloon catheters
JP5813391B2 (ja) * 2011-06-24 2015-11-17 日東電工株式会社 粒子製剤の製造方法
CN102805733B (zh) 2011-06-01 2016-03-09 日东电工株式会社 颗粒制剂及其制造方法
EP2741736B1 (en) 2011-08-12 2017-11-22 Boehringer Ingelheim Vetmedica GmbH Taste masked pharmaceutical composition
AU2012101682B4 (en) 2011-11-20 2013-10-24 Betrola Investments Pty Limited Formulation
HRP20151347T1 (hr) * 2011-12-21 2016-01-01 Novartis Tiergesundheit Ag Nova kombinacija
EP2825159B1 (en) 2012-03-15 2022-06-22 Boehringer Ingelheim Vetmedica GmbH Pharmaceutical tablet formulation for the veterinary medical sector, method of production and use thereof
GB201207886D0 (en) 2012-05-04 2012-06-20 Jagotec Ag Improvements in or relating to organic compounds
SG11201407200TA (en) 2012-05-18 2014-12-30 Luoda Pharma Pty Ltd Liquid formulation
CN103655502A (zh) 2012-08-31 2014-03-26 瑞普（天津）生物药业有限公司 一种宠物用匹莫苯丹缓释片及其制备方法
FR3002736B1 (fr) 2013-03-04 2015-06-26 Virbac Composition orale nutritionnelle et medicamenteuse a usage veterinaire
PL3021832T3 (pl) 2013-07-19 2021-08-23 Boehringer Ingelheim Vetmedica Gmbh Konserwowana ciekła wodna kompozycja farmaceutyczna zawierająca eteryfikowane pochodne cyklodekstryny
AU2014359427B2 (en) 2013-12-04 2017-04-20 Boehringer Ingelheim Vetmedica Gmbh Improved pharmaceutical compositions of pimobendan
EP3389638B1 (en) 2015-12-17 2023-08-02 Ceva Santé Animale Pharmaceutical composition comprising pimobendan
US10537570B2 (en) 2016-04-06 2020-01-21 Boehringer Ingelheim Vetmedica Gmbh Use of pimobendan for the reduction of heart size and/or the delay of onset of clinical symptoms in patients with asymptomatic heart failure due to mitral valve disease
JP2022554144A (ja) 2019-10-23 2022-12-28 ピードモント アニマル ヘルス インコーポレイテッド ピモベンダン製剤およびその使用方法
CN112618505B (zh) 2020-12-30 2022-11-15 南京朗博特动物药业有限公司 一种宠物用含有贝那普利和匹莫苯丹的复方药物组合物及其制备方法

Similar Documents

Publication Publication Date Title
JP2016108346A5 (cg-RX-API-DMAC7.html)
JP5905999B2 (ja) ピモベンダンの改善された医薬組成物
AU2018253545A1 (en) Microcrystalline diketopiperazine compositions and methods
JP2014516080A5 (cg-RX-API-DMAC7.html)
WO2005079755A3 (en) Interleukin-13 antagonist powders, spray-dried particles, and methods
HRP20211606T1 (hr) Oralni farmaceutski pripravci dabigatran-eteksilata
HRP20241719T1 (hr) Antitumorske smjese
HRP20170014T1 (hr) Farmaceutski pripravak za inhalaciju
RU2014140539A (ru) Агрегированные частицы
TW200640502A (en) Tablets with improved drug substance dispersibility
MX2017004476A (es) Composicion que comprende al menos un polvo seco obtenido por secado por atomizacion para aumentar la estabilidad de la formulacion.
JP2012509922A5 (cg-RX-API-DMAC7.html)
US8821942B1 (en) Highly compressible, low density ground calcium carbonate granulation and a related method of preparation
JP5619970B2 (ja) 生理活性物質含有粒子の製造方法
WO2009120619A3 (en) Nuclease compositions, methods of making and using such compositions, and systems for pulmonary delivery of such compositions
CN106692093A (zh) 一种琥珀酸美托洛尔缓释片及其制备方法
GB2575935A8 (en) Method for coating particles
JP2012087147A5 (cg-RX-API-DMAC7.html)
CN109864980A (zh) 阿利吉仑胶囊及其制备方法
TH128465A (th) ผลิตภัณฑ์ดูแลช่องปาก และวิธีการใช้ และวิธีการผลิตผลิตภัณฑ์นี้