JP2016106149A5 - - Google Patents
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- Publication number
- JP2016106149A5 JP2016106149A5 JP2016051146A JP2016051146A JP2016106149A5 JP 2016106149 A5 JP2016106149 A5 JP 2016106149A5 JP 2016051146 A JP2016051146 A JP 2016051146A JP 2016051146 A JP2016051146 A JP 2016051146A JP 2016106149 A5 JP2016106149 A5 JP 2016106149A5
- Authority
- JP
- Japan
- Prior art keywords
- formula
- pharmaceutically acceptable
- acceptable salt
- hepatitis
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000003839 salts Chemical class 0.000 claims 4
- 208000005176 Hepatitis C Diseases 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 2
- 230000000069 prophylactic effect Effects 0.000 claims 2
- 230000001225 therapeutic effect Effects 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41481810P | 2010-11-17 | 2010-11-17 | |
| US61/414,818 | 2010-11-17 | ||
| US201161504924P | 2011-07-06 | 2011-07-06 | |
| US61/504,924 | 2011-07-06 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013539970A Division JP5905020B2 (ja) | 2010-11-17 | 2011-11-16 | 抗ウイルス化合物 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017240524A Division JP2018039851A (ja) | 2010-11-17 | 2017-12-15 | 抗ウイルス化合物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016106149A JP2016106149A (ja) | 2016-06-16 |
| JP2016106149A5 true JP2016106149A5 (enExample) | 2016-10-20 |
Family
ID=45099196
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013539970A Active JP5905020B2 (ja) | 2010-11-17 | 2011-11-16 | 抗ウイルス化合物 |
| JP2016051146A Pending JP2016106149A (ja) | 2010-11-17 | 2016-03-15 | 抗ウイルス化合物 |
| JP2017240524A Withdrawn JP2018039851A (ja) | 2010-11-17 | 2017-12-15 | 抗ウイルス化合物 |
| JP2019206819A Withdrawn JP2020037584A (ja) | 2010-11-17 | 2019-11-15 | 抗ウイルス化合物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013539970A Active JP5905020B2 (ja) | 2010-11-17 | 2011-11-16 | 抗ウイルス化合物 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017240524A Withdrawn JP2018039851A (ja) | 2010-11-17 | 2017-12-15 | 抗ウイルス化合物 |
| JP2019206819A Withdrawn JP2020037584A (ja) | 2010-11-17 | 2019-11-15 | 抗ウイルス化合物 |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US9156823B2 (enExample) |
| EP (3) | EP2640719B1 (enExample) |
| JP (4) | JP5905020B2 (enExample) |
| KR (5) | KR20200140924A (enExample) |
| AR (1) | AR083711A1 (enExample) |
| AU (3) | AU2011328980B2 (enExample) |
| CA (3) | CA2817840A1 (enExample) |
| ES (1) | ES2634095T3 (enExample) |
| HK (1) | HK1250162A1 (enExample) |
| IL (1) | IL226346A (enExample) |
| NZ (2) | NZ726475A (enExample) |
| PL (1) | PL2640719T3 (enExample) |
| PT (1) | PT2640719T (enExample) |
| SG (2) | SG190785A1 (enExample) |
| SI (1) | SI2640719T1 (enExample) |
| TW (3) | TWI640526B (enExample) |
| UY (1) | UY33735A (enExample) |
| WO (1) | WO2012068234A2 (enExample) |
Families Citing this family (69)
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| HUE029877T2 (en) | 2003-05-30 | 2017-04-28 | Gilead Pharmasset Llc | Modified fluorinated nucleoside analogues |
| EA027493B1 (ru) | 2009-05-13 | 2017-07-31 | Джилид Фармассет Ллс | Промежуточные соединения для получения противовирусного соединения |
| US8937150B2 (en) | 2009-06-11 | 2015-01-20 | Abbvie Inc. | Anti-viral compounds |
| ES2414934T3 (es) | 2009-06-11 | 2013-07-23 | Abbvie Bahamas Limited | Inhibidores del virus de la Hepatitis C |
| CA2800530A1 (en) * | 2010-05-28 | 2011-12-01 | Presidio Pharmaceuticals, Inc. | Inhibitors of hcv ns5a |
| NZ605440A (en) | 2010-06-10 | 2014-05-30 | Abbvie Bahamas Ltd | Solid compositions comprising an hcv inhibitor |
| WO2012068234A2 (en) | 2010-11-17 | 2012-05-24 | Gilead Sciences, Inc. | Antiviral compounds |
| US8552047B2 (en) | 2011-02-07 | 2013-10-08 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US9546160B2 (en) | 2011-05-12 | 2017-01-17 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US10201584B1 (en) | 2011-05-17 | 2019-02-12 | Abbvie Inc. | Compositions and methods for treating HCV |
| PH12014500557A1 (en) | 2011-09-16 | 2014-05-26 | Gilead Pharmasset Llc | Methods for treating hcv |
| PL2907816T3 (pl) | 2011-11-16 | 2019-03-29 | Gilead Pharmasset Llc | Skondensowane imidazolyloimidazole jako związki przeciwwirusowe |
| AU2015252077A1 (en) * | 2011-11-16 | 2015-11-19 | Gilead Pharmasset Llc | Antiviral compounds |
| US9034832B2 (en) | 2011-12-29 | 2015-05-19 | Abbvie Inc. | Solid compositions |
| US9326973B2 (en) | 2012-01-13 | 2016-05-03 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| NZ628515A (en) | 2012-02-10 | 2016-06-24 | Lupin Ltd | Antiviral compounds with a dibenzooxaheterocycle moiety |
| US20130309196A1 (en) * | 2012-05-16 | 2013-11-21 | Gilead Sciences, Inc. | Antiviral compounds |
| US9079887B2 (en) | 2012-05-16 | 2015-07-14 | Gilead Sciences, Inc. | Antiviral compounds |
| US9233974B2 (en) * | 2012-12-21 | 2016-01-12 | Gilead Sciences, Inc. | Antiviral compounds |
| SG11201506021XA (en) | 2013-01-31 | 2015-08-28 | Gilead Pharmasset Llc | Combination formulation of two antiviral compounds |
| JP5614568B1 (ja) * | 2013-02-07 | 2014-10-29 | 保土谷化学工業株式会社 | ジアザトリフェニレン環構造を有する化合物および有機エレクトロルミネッセンス素子 |
| US11484534B2 (en) | 2013-03-14 | 2022-11-01 | Abbvie Inc. | Methods for treating HCV |
| WO2014185995A1 (en) * | 2013-05-16 | 2014-11-20 | Gilead Pharmasset Llc | Hepatitis c treatments with sofosbuvir |
| CN104211677B (zh) * | 2013-05-30 | 2018-02-23 | 浙江九洲药业股份有限公司 | 一种抗丙型肝炎药物中间体的制备方法 |
| CN104211565A (zh) * | 2013-05-31 | 2014-12-17 | 浙江九洲药业股份有限公司 | 一种抗丙型肝炎药物中间体的制备方法 |
| WO2014206257A1 (zh) | 2013-06-26 | 2014-12-31 | 浙江九洲药业股份有限公司 | 一种2-羧酸吡咯烷衍生物的制备方法 |
| US9717712B2 (en) | 2013-07-02 | 2017-08-01 | Bristol-Myers Squibb Company | Combinations comprising tricyclohexadecahexaene derivatives for use in the treatment of hepatitis C virus |
| US20150023913A1 (en) | 2013-07-02 | 2015-01-22 | Bristol-Myers Squibb Company | Hepatitis C Virus Inhibitors |
| US9775831B2 (en) | 2013-07-17 | 2017-10-03 | Bristol-Myers Squibb Company | Combinations comprising biphenyl derivatives for use in the treatment of HCV |
| WO2015030854A1 (en) * | 2013-08-27 | 2015-03-05 | Gilead Pharmasset Llc | Solid dispersion formulation of an antiviral compound |
| EP3038601B1 (en) * | 2013-08-27 | 2020-04-08 | Gilead Pharmasset LLC | Combination formulation of two antiviral compounds |
| CN104418784B (zh) * | 2013-09-04 | 2019-02-19 | 浙江九洲药业股份有限公司 | 一种抗病毒药物中间体的拆分方法 |
| WO2015089810A1 (en) * | 2013-12-20 | 2015-06-25 | Merck Sharp & Dohme Corp. | Fused tetracyclic heterocyclic compounds and methods of use thereof for the treatment of viral diseases |
| US9512108B2 (en) | 2013-12-31 | 2016-12-06 | Nanjing Sanhome Pharmaceutical Co., Ltd. | 9,9,10,10-Tetrafluoro-9,10-dihydrophenanthrene hepatitis C virus inhibitor and application thereof |
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| WO2015184644A1 (zh) * | 2014-06-06 | 2015-12-10 | 爱博新药研发(上海)有限公司 | 抑制丙肝病毒的化合物、药物组合物及其应用 |
| TWI721947B (zh) | 2014-06-11 | 2021-03-21 | 美商基利法瑪席特有限責任公司 | 抗病毒化合物的固態形式 |
| TWI679203B (zh) | 2014-06-11 | 2019-12-11 | 美商基利法瑪席特有限責任公司 | 製備抗病毒化合物之方法 |
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| SMT202100592T1 (it) | 2014-12-26 | 2021-11-12 | Univ Emory | Derivati antivirali della n4-idrossicitidina |
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| TWI703141B (zh) * | 2015-03-12 | 2020-09-01 | 大陸商廣東東陽光藥業有限公司 | 作為丙型肝炎抑制劑的化合物及其在藥物中的應用 |
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| WO2017181383A1 (en) | 2016-04-21 | 2017-10-26 | Merck Sharp & Dohme Corp. | Hepatitis c virus inhibitors |
| EP3454862B1 (en) | 2016-05-10 | 2024-09-11 | C4 Therapeutics, Inc. | Spirocyclic degronimers for target protein degradation |
| WO2017197051A1 (en) | 2016-05-10 | 2017-11-16 | C4 Therapeutics, Inc. | Amine-linked c3-glutarimide degronimers for target protein degradation |
| WO2017197046A1 (en) | 2016-05-10 | 2017-11-16 | C4 Therapeutics, Inc. | C3-carbon linked glutarimide degronimers for target protein degradation |
| EP4491236A3 (en) | 2016-05-10 | 2025-04-02 | C4 Therapeutics, Inc. | Heterocyclic degronimers for target protein degradation |
| CN118178652A (zh) | 2016-05-27 | 2024-06-14 | 吉利德科学公司 | 使用ns5a、ns5b或ns3抑制剂治疗乙型肝炎病毒感染的方法 |
| CN106432197B (zh) * | 2016-09-07 | 2019-12-10 | 上海众强药业有限公司 | 一种雷迪帕韦中间体单对甲苯磺酸盐、其晶型及其制备方法 |
| CN107759577B (zh) * | 2016-11-30 | 2020-03-27 | 上海博志研新药物技术有限公司 | Gs5816中间体、制备方法及应用 |
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| CN118440096A (zh) | 2017-06-20 | 2024-08-06 | C4医药公司 | 用于蛋白降解的n/o-连接的降解决定子和降解决定子体 |
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-
2011
- 2011-11-16 WO PCT/US2011/060966 patent/WO2012068234A2/en not_active Ceased
- 2011-11-16 JP JP2013539970A patent/JP5905020B2/ja active Active
- 2011-11-16 PL PL11791700T patent/PL2640719T3/pl unknown
- 2011-11-16 KR KR1020207034568A patent/KR20200140924A/ko not_active Ceased
- 2011-11-16 US US13/884,578 patent/US9156823B2/en active Active
- 2011-11-16 SG SG2013036223A patent/SG190785A1/en unknown
- 2011-11-16 CA CA2817840A patent/CA2817840A1/en not_active Abandoned
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