JP2016047845A5 - - Google Patents
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- JP2016047845A5 JP2016047845A5 JP2015247222A JP2015247222A JP2016047845A5 JP 2016047845 A5 JP2016047845 A5 JP 2016047845A5 JP 2015247222 A JP2015247222 A JP 2015247222A JP 2015247222 A JP2015247222 A JP 2015247222A JP 2016047845 A5 JP2016047845 A5 JP 2016047845A5
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- Prior art keywords
- nucleic acid
- sequence
- cells
- seq
- acid sequence
- Prior art date
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Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26020209P | 2009-11-11 | 2009-11-11 | |
| EP09014136.7 | 2009-11-11 | ||
| EP09014136A EP2322555A1 (en) | 2009-11-11 | 2009-11-11 | Antibodies specific for claudin 6 (CLDN6) |
| US61/260,202 | 2009-11-11 | ||
| US36161810P | 2010-07-06 | 2010-07-06 | |
| EP10006956 | 2010-07-06 | ||
| EP10006956.6 | 2010-07-06 | ||
| US61/361,618 | 2010-07-06 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012538239A Division JP5889196B2 (ja) | 2009-11-11 | 2010-11-11 | クローディン６（ｃｌｄｎ６）に特異的な抗体 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017075017A Division JP6502992B2 (ja) | 2009-11-11 | 2017-04-05 | クローディン６（ｃｌｄｎ６）に特異的な抗体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016047845A JP2016047845A (ja) | 2016-04-07 |
| JP2016047845A5 true JP2016047845A5 (enExample) | 2016-06-23 |
| JP6125604B2 JP6125604B2 (ja) | 2017-05-10 |
Family
ID=43480734
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012538239A Active JP5889196B2 (ja) | 2009-11-11 | 2010-11-11 | クローディン６（ｃｌｄｎ６）に特異的な抗体 |
| JP2015247222A Active JP6125604B2 (ja) | 2009-11-11 | 2015-12-18 | クローディン６（ｃｌｄｎ６）に特異的な抗体 |
| JP2017075017A Active JP6502992B2 (ja) | 2009-11-11 | 2017-04-05 | クローディン６（ｃｌｄｎ６）に特異的な抗体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012538239A Active JP5889196B2 (ja) | 2009-11-11 | 2010-11-11 | クローディン６（ｃｌｄｎ６）に特異的な抗体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017075017A Active JP6502992B2 (ja) | 2009-11-11 | 2017-04-05 | クローディン６（ｃｌｄｎ６）に特異的な抗体 |
Country Status (29)
| Country | Link |
|---|---|
| US (5) | US9487584B2 (enExample) |
| EP (4) | EP3689911B1 (enExample) |
| JP (3) | JP5889196B2 (enExample) |
| KR (4) | KR102126964B1 (enExample) |
| CN (4) | CN106432500B (enExample) |
| AU (3) | AU2010318316B2 (enExample) |
| BR (1) | BR112012011143B1 (enExample) |
| CA (2) | CA3050655C (enExample) |
| CY (2) | CY1120300T1 (enExample) |
| DK (2) | DK2499161T3 (enExample) |
| ES (3) | ES2784483T3 (enExample) |
| HR (2) | HRP20171749T1 (enExample) |
| HU (2) | HUE049404T2 (enExample) |
| IL (2) | IL218628B (enExample) |
| LT (2) | LT2499161T (enExample) |
| ME (1) | ME02943B (enExample) |
| MX (3) | MX385874B (enExample) |
| NO (1) | NO2499161T3 (enExample) |
| NZ (2) | NZ716587A (enExample) |
| PL (3) | PL3689911T3 (enExample) |
| PT (2) | PT3305813T (enExample) |
| RS (2) | RS60168B1 (enExample) |
| RU (1) | RU2675997C2 (enExample) |
| SG (2) | SG10201500975YA (enExample) |
| SI (2) | SI3305813T1 (enExample) |
| SM (1) | SMT201700566T1 (enExample) |
| UA (2) | UA128302C2 (enExample) |
| WO (1) | WO2011057788A1 (enExample) |
| ZA (1) | ZA201202418B (enExample) |
Families Citing this family (48)
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| JPS6358588A (ja) * | 1986-08-29 | 1988-03-14 | Toshiba Corp | バ−コ−ド読取装置 |
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| US12492253B1 (en) * | 2008-02-25 | 2025-12-09 | Xencor, Inc. | Anti-human C5 antibodies |
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| EP3689911B1 (en) | 2009-11-11 | 2024-08-21 | Astellas Pharma Inc. | Antibodies specific for claudin 6 (cldn6) |
| EP2404936A1 (en) | 2010-07-06 | 2012-01-11 | Ganymed Pharmaceuticals AG | Cancer therapy using CLDN6 target-directed antibodies in vivo |
| TWI736437B (zh) | 2010-11-30 | 2021-08-11 | 日商中外製藥股份有限公司 | 細胞傷害誘導治療劑 |
| EP3026064B1 (en) * | 2011-05-13 | 2018-10-17 | Ganymed Pharmaceuticals GmbH | Antibodies for treatment of cancer expressing claudin 6 |
| TR201821021T4 (tr) * | 2011-05-13 | 2019-01-21 | Ganymed Pharmaceuticals Gmbh | Kanser tedavi̇si̇ne yöneli̇k claudin 6 ekspresyonlu anti̇korlar. |
| CN103320381B (zh) * | 2012-03-23 | 2015-04-15 | 上海市儿童医院 | 一种多能干细胞表面标志物及其用途 |
| PL3489261T3 (pl) | 2012-08-24 | 2021-08-16 | The Regents Of The University Of California | Przeciwciała i szczepionki do stosowania w leczeniu nowotworów z ekspresją ROR1 i w hamowaniu przerzutu |
| EP2920209B1 (en) * | 2012-11-13 | 2020-08-05 | BioNTech SE | Agents for treatment of claudin expressing cancer diseases |
| IL282953B2 (en) * | 2012-11-13 | 2026-02-01 | Tron Translationale Onkologie An Der Johannes Gutenberg Univ Mainz Gemeinnutzige Gmbh | Agents for the treatment of claudin-expressing cancers |
| EP3027208B1 (en) * | 2013-07-31 | 2020-06-24 | Biontech AG | Diagnosis and therapy of cancer involving cancer stem cells |
| WO2015014376A1 (en) * | 2013-07-31 | 2015-02-05 | Biontech Ag | Diagnosis and therapy of cancer involving cancer stem cells |
| AU2014346792A1 (en) * | 2013-11-06 | 2016-06-02 | Abbvie Stemcentrx Llc | Novel anti-claudin antibodies and methods of use |
| CA2929044A1 (en) | 2013-11-11 | 2015-05-14 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule containing modified antibody variable region |
| CN106459165B (zh) * | 2014-04-01 | 2021-04-20 | 拜恩科技细胞&基因治疗有限公司 | 密封蛋白-6特异性免疫受体和t细胞表位 |
| MA40921A (fr) * | 2014-11-05 | 2017-09-12 | Abbvie Stemcentrx Llc | Récepteurs antigéniques chimériques anti-cldn et procédés d'utilisation |
| US11154615B2 (en) | 2014-11-11 | 2021-10-26 | Chugai Seiyaku Kabushiki Kaisha | Library of antigen-binding molecules including modified antibody variable region |
| KR20230047507A (ko) | 2016-06-27 | 2023-04-07 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | 암 치료 조합 |
| JP6900051B2 (ja) * | 2016-12-07 | 2021-07-07 | 国立大学法人大阪大学 | Ｃｌａｕｄｉｎ ５抗体、及びその抗体を含有する医薬 |
| KR102667026B1 (ko) * | 2017-05-08 | 2024-05-20 | 고꾸리쯔 다이가꾸 호우징 오사까 다이가꾸 | 항 cldn-5 항체, 및 그 항체를 함유하는 의약 |
| WO2019048040A1 (en) * | 2017-09-06 | 2019-03-14 | Ganymed Pharmaceuticals Gmbh | ANTIBODIES USEFUL IN THE DIAGNOSIS OF CANCER |
| CA3177215C (en) | 2017-09-29 | 2026-06-09 | Daiichi Sankyo Company, Limited | Antibody-pyrrolobenzodiazepine derivative conjugate |
| JP7357616B2 (ja) | 2017-12-05 | 2023-10-06 | 中外製薬株式会社 | Ｃｄ３およびｃｄ１３７に結合する改変された抗体可変領域を含む抗原結合分子 |
| JP2021510064A (ja) * | 2018-01-05 | 2021-04-15 | 中外製薬株式会社 | 細胞傷害誘導治療剤 |
| WO2020075325A1 (ja) * | 2018-10-09 | 2020-04-16 | 公立大学法人福島県立医科大学 | 子宮体癌患者の予後予測バイオマーカー |
| CN119708241A (zh) | 2019-02-15 | 2025-03-28 | 因特格尔莫来库乐有限公司 | 密封蛋白6抗体及其用途 |
| DK3941946T3 (da) | 2019-03-20 | 2025-03-24 | Univ California | Claudin-6-antistoffer og lægemiddelkonjugater |
| EP3950061A4 (en) | 2019-03-25 | 2022-11-16 | Daiichi Sankyo Company, Limited | ANTIBODY PYRROLOBENZODIAZEPINE DERIVATIVE CONJUGATE |
| JP7359864B2 (ja) * | 2019-07-10 | 2023-10-11 | 中外製薬株式会社 | クローディン６結合分子およびその使用 |
| CN111087465B (zh) * | 2019-12-24 | 2020-12-08 | 广州医科大学 | 一种针对密蛋白6的抗体偶联药物及应用 |
| PH12022552323A1 (en) | 2020-03-31 | 2023-12-04 | Chugai Pharmaceutical Co Ltd | Claudin-6 targeting multispecific antigen-binding molecules and uses thereof |
| US20240150455A1 (en) * | 2021-03-05 | 2024-05-09 | Shanghai GenBase Biotechnology Co., Ltd. | Anti-cldn6 antibody and use thereof |
| EP4305067A1 (en) | 2021-03-09 | 2024-01-17 | Xencor, Inc. | Heterodimeric antibodies that bind cd3 and cldn6 |
| JPWO2023053282A1 (enExample) | 2021-09-29 | 2023-04-06 | ||
| EP4562046A1 (en) * | 2022-07-29 | 2025-06-04 | Legend Biotech Ireland Limited | Claudin-6 binding moieties and uses thereof |
| AU2023373601A1 (en) | 2022-10-31 | 2025-04-03 | Astellas Pharma Inc. | Antibody-drug conjugate containing a toll-like receptor 7/8 dual agonist compound |
| CN120282987A (zh) | 2022-11-30 | 2025-07-08 | 因特格尔莫来库乐有限公司 | 包括双特异性型式的针对紧密连接蛋白6的抗体 |
| CN116064622B (zh) * | 2023-02-13 | 2023-10-13 | 优睿赛思(武汉)生物科技有限公司 | Claudin6-mCherry报告基因CHO-K1稳转细胞株制备及应用 |
| CN121219323A (zh) * | 2023-05-12 | 2025-12-26 | 智泽童康(广州)生物科技有限公司 | 抗cldn6抗体及其用途 |
| KR20260015262A (ko) | 2023-05-25 | 2026-02-02 | 더 리전트 오브 더 유니버시티 오브 캘리포니아 | 암 치료를 위한 클라우딘-6 접합체의 투여량 |
| WO2025149667A1 (en) | 2024-01-12 | 2025-07-17 | Pheon Therapeutics Ltd | Antibody drug conjugates and uses thereof |
| CN119371534B (zh) * | 2024-08-21 | 2025-05-27 | 百吉生物医药(广州)股份有限公司 | 一种紧密连接蛋白抗体e02及其应用 |
| CN119320451B (zh) * | 2024-08-21 | 2025-05-16 | 百吉生物医药(广州)股份有限公司 | 一种紧密连接蛋白抗体d03及其应用 |
| CN118754987B (zh) * | 2024-08-21 | 2025-02-11 | 广州百吉生物制药有限公司 | 一种紧密连接蛋白抗体h04及其应用 |
| WO2026084392A1 (ko) * | 2024-10-14 | 2026-04-23 | 에이비엘바이오 주식회사 | 항-클라우딘6 항체 및 이의 용도 |
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| US20150166630A1 (en) | 2012-07-19 | 2015-06-18 | Amgen Inc. | Btnl3 proteins, nucleic acids, and antibodies and uses thereof |
| IL282953B2 (en) * | 2012-11-13 | 2026-02-01 | Tron Translationale Onkologie An Der Johannes Gutenberg Univ Mainz Gemeinnutzige Gmbh | Agents for the treatment of claudin-expressing cancers |
| CN106459165B (zh) * | 2014-04-01 | 2021-04-20 | 拜恩科技细胞&基因治疗有限公司 | 密封蛋白-6特异性免疫受体和t细胞表位 |
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