|
US3773919A
(en)
|
1969-10-23 |
1973-11-20 |
Du Pont |
Polylactide-drug mixtures
|
|
US4002531A
(en)
|
1976-01-22 |
1977-01-11 |
Pierce Chemical Company |
Modifying enzymes with polyethylene glycol and product produced thereby
|
|
USRE30985E
(en)
|
1978-01-01 |
1982-06-29 |
|
Serum-free cell culture media
|
|
US4560655A
(en)
|
1982-12-16 |
1985-12-24 |
Immunex Corporation |
Serum-free cell culture medium and process for making same
|
|
US4657866A
(en)
|
1982-12-21 |
1987-04-14 |
Sudhir Kumar |
Serum-free, synthetic, completely chemically defined tissue culture media
|
|
WO2001007657A1
(en)
|
1999-07-27 |
2001-02-01 |
Phylos, Inc. |
Peptide acceptor ligation methods
|
|
US4767704A
(en)
|
1983-10-07 |
1988-08-30 |
Columbia University In The City Of New York |
Protein-free culture medium
|
|
GB8516415D0
(en)
|
1985-06-28 |
1985-07-31 |
Celltech Ltd |
Culture of animal cells
|
|
US4927762A
(en)
|
1986-04-01 |
1990-05-22 |
Cell Enterprises, Inc. |
Cell culture medium with antioxidant
|
|
US5514581A
(en)
|
1986-11-04 |
1996-05-07 |
Protein Polymer Technologies, Inc. |
Functional recombinantly prepared synthetic protein polymer
|
|
US5770697A
(en)
|
1986-11-04 |
1998-06-23 |
Protein Polymer Technologies, Inc. |
Peptides comprising repetitive units of amino acids and DNA sequences encoding the same
|
|
US5641648A
(en)
|
1986-11-04 |
1997-06-24 |
Protein Polymer Technologies, Inc. |
Methods for preparing synthetic repetitive DNA
|
|
US6018030A
(en)
|
1986-11-04 |
2000-01-25 |
Protein Polymer Technologies, Inc. |
Peptides comprising repetitive units of amino acids and DNA sequences encoding the same
|
|
US4863457A
(en)
|
1986-11-24 |
1989-09-05 |
Lee David A |
Drug delivery device
|
|
US4997652A
(en)
|
1987-12-22 |
1991-03-05 |
Visionex |
Biodegradable ocular implants
|
|
AU632065B2
(en)
|
1988-09-23 |
1992-12-17 |
Novartis Vaccines And Diagnostics, Inc. |
Cell culture medium for enhanced cell growth, culture longevity and product expression
|
|
EP0470128B2
(en)
|
1989-04-19 |
2003-08-13 |
Enzon, Inc. |
Active carbonates of polyalkylene oxides for modification of polypeptides
|
|
FR2646437B1
(fr)
|
1989-04-28 |
1991-08-30 |
Transgene Sa |
Nouvelles sequences d'adn, leur application en tant que sequence codant pour un peptide signal pour la secretion de proteines matures par des levures recombinantes, cassettes d'expression, levures transformees et procede de preparation de proteines correspondant
|
|
US5164188A
(en)
|
1989-11-22 |
1992-11-17 |
Visionex, Inc. |
Biodegradable ocular implants
|
|
AU8498091A
(en)
|
1990-08-02 |
1992-03-02 |
Regents Of The University Of Colorado, The |
Systematic polypeptide evolution by reverse translation
|
|
JP3051145B2
(ja)
|
1990-08-28 |
2000-06-12 |
住友製薬株式会社 |
新規なポリエチレングリコール誘導体修飾ペプチド
|
|
US5122469A
(en)
|
1990-10-03 |
1992-06-16 |
Genentech, Inc. |
Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins
|
|
KR0185215B1
(ko)
|
1990-11-30 |
1999-05-01 |
요시다 쇼오지 |
서방성 안구삽입용 약제
|
|
US5773574A
(en)
|
1990-12-03 |
1998-06-30 |
The Scripps Research Institute |
Polypeptides for promoting cell attachment
|
|
US5235041A
(en)
|
1990-12-28 |
1993-08-10 |
Protein Polymer Technologies, Inc. |
Purification of structurally ordered recombinant protein polymers
|
|
US5792742A
(en)
|
1991-06-14 |
1998-08-11 |
New York University |
Fibrin-binding peptide fragments of fibronectin
|
|
AU2313392A
(en)
|
1991-08-01 |
1993-03-02 |
University Research Corporation |
Systematic polypeptide evolution by reverse translation
|
|
AU673190B2
(en)
|
1992-07-13 |
1996-10-31 |
Bionebraska, Inc. |
Method for modification of recombinant polypeptides
|
|
MD1367C2
(ro)
|
1992-11-13 |
2000-11-30 |
Idec Pharmaceuticals Corporation |
Metode de tratament al limfomului celulelor B, anticorpi anti-CD20, hibridom.
|
|
WO1994017097A1
(en)
|
1993-01-19 |
1994-08-04 |
Regents Of The University Of Minnesota |
Synthetic fibronectin fragments as inhibitors of retroviral infections
|
|
PT654256E
(pt)
|
1993-02-26 |
2000-12-29 |
Santen Pharmaceutical Co Ltd |
Rolha de esclerotica biodegradavel
|
|
US5643575A
(en)
|
1993-10-27 |
1997-07-01 |
Enzon, Inc. |
Non-antigenic branched polymer conjugates
|
|
AU8124694A
(en)
|
1993-10-29 |
1995-05-22 |
Affymax Technologies N.V. |
In vitro peptide and antibody display libraries
|
|
US5443505A
(en)
|
1993-11-15 |
1995-08-22 |
Oculex Pharmaceuticals, Inc. |
Biocompatible ocular implants
|
|
US5516522A
(en)
|
1994-03-14 |
1996-05-14 |
Board Of Supervisors Of Louisiana State University |
Biodegradable porous device for long-term drug delivery with constant rate release and method of making the same
|
|
US5824784A
(en)
|
1994-10-12 |
1998-10-20 |
Amgen Inc. |
N-terminally chemically modified protein compositions and methods
|
|
US5932462A
(en)
|
1995-01-10 |
1999-08-03 |
Shearwater Polymers, Inc. |
Multiarmed, monofunctional, polymer for coupling to molecules and surfaces
|
|
US5559000A
(en)
|
1995-01-18 |
1996-09-24 |
The Scripps Research Institute |
Encoded reaction cassette
|
|
US6369116B1
(en)
|
1995-06-02 |
2002-04-09 |
Oculex Pharmaceuticals, Inc. |
Composition and method for treating glaucoma
|
|
US5869079A
(en)
|
1995-06-02 |
1999-02-09 |
Oculex Pharmaceuticals, Inc. |
Formulation for controlled release of drugs by combining hydrophilic and hydrophobic agents
|
|
DE19646372C1
(de)
|
1995-11-11 |
1997-06-19 |
Evotec Biosystems Gmbh |
Genotyp und Phänotyp koppelnde Verbindung
|
|
GB9618960D0
(en)
|
1996-09-11 |
1996-10-23 |
Medical Science Sys Inc |
Proteases
|
|
US5922676A
(en)
|
1996-09-20 |
1999-07-13 |
The Burnham Institute |
Methods of inhibiting cancer by using superfibronectin
|
|
DE69730157T2
(de)
|
1996-10-17 |
2005-07-28 |
Mitsubishi Chemical Corp. |
Molekül, welches genotyp und phänotyp zusammenführt und dessen anwendungen
|
|
JP3837748B2
(ja)
|
1997-01-17 |
2006-10-25 |
東亞合成株式会社 |
Ｖｅｇｆ結合性ポリペプチド
|
|
DK1712623T3
(da)
|
1997-01-21 |
2012-02-06 |
Gen Hospital Corp |
Udvælgelse af proteiner ved anvendelse af RNA-proteinfusioner
|
|
US6261804B1
(en)
|
1997-01-21 |
2001-07-17 |
The General Hospital Corporation |
Selection of proteins using RNA-protein fusions
|
|
EP0981548A4
(en)
*
|
1997-04-30 |
2005-11-23 |
Enzon Inc |
GLYCOSYLATABLE SINGLE CHAIN ANTIGEN-BINDING PROTEINS, MANUFACTURE AND USE THEREOF
|
|
EP1958962A3
(en)
|
1997-06-12 |
2013-05-01 |
Novartis International Pharmaceutical Ltd. |
Artificial antibody polypeptides
|
|
US6159722A
(en)
|
1997-12-03 |
2000-12-12 |
Boehringer Mannheim Gmbh |
Chimeric serine proteases
|
|
AU3463699A
(en)
|
1998-04-03 |
1999-10-25 |
Phylos, Inc. |
Addressable protein arrays
|
|
US20030045681A1
(en)
|
1998-05-11 |
2003-03-06 |
Anthony J. Zelano |
Specific binding molecules for scintigraphy, conjugates containing them and therapeutic method for treatment of angiogenesis
|
|
JP4108827B2
(ja)
|
1998-05-28 |
2008-06-25 |
大日本印刷株式会社 |
無機質系化粧板
|
|
WO2000034317A2
(en)
|
1998-12-08 |
2000-06-15 |
Biovation Limited |
Method for reducing immunogenicity of proteins
|
|
DE69941267D1
(de)
|
1998-12-10 |
2009-09-24 |
Bristol Myers Squibb Co |
Proteingerüste für antikörper-nachahmer und andere bindende proteine
|
|
GB9827228D0
(en)
|
1998-12-10 |
1999-02-03 |
Univ Nottingham |
Cancer detection method and reagents
|
|
US7115396B2
(en)
*
|
1998-12-10 |
2006-10-03 |
Compound Therapeutics, Inc. |
Protein scaffolds for antibody mimics and other binding proteins
|
|
US6818418B1
(en)
*
|
1998-12-10 |
2004-11-16 |
Compound Therapeutics, Inc. |
Protein scaffolds for antibody mimics and other binding proteins
|
|
EP1179541B1
(en)
|
1999-04-28 |
2004-06-16 |
Board Of Regents, The University Of Texas System |
Compositions and methods for cancer treatment by selectively inhibiting VEGF
|
|
US6399857B1
(en)
|
1999-09-22 |
2002-06-04 |
Paradigm Genetics, Inc. |
Modified nucleotide sequence encoding a LexA DNA binding domain optimized for arabidopsis species
|
|
JP2003528632A
(ja)
|
2000-03-31 |
2003-09-30 |
インスティティ・パスツール |
血管内皮成長因子（ｖｅｇｆ）−媒介性脈管形成を阻害するペプチド、該ペプチドをエンコードするポリヌクレオチド及びその使用方法
|
|
AU2001268481A1
(en)
|
2000-06-15 |
2001-12-24 |
Board Of Regents, The University Of Texas System |
Regulatable, catalytically active nucleic acids
|
|
CA2416219C
(en)
|
2000-07-11 |
2016-10-11 |
Research Corporation Technologies, Inc. |
Artificial antibody polypeptides
|
|
US7052686B2
(en)
|
2000-09-29 |
2006-05-30 |
Schering Corporation |
Pegylated interleukin-10
|
|
CA2418835A1
(en)
|
2000-10-16 |
2002-04-25 |
Phylos, Inc. |
Protein scaffolds for antibody mimics and other binding proteins
|
|
US7598352B2
(en)
|
2000-11-17 |
2009-10-06 |
University Of Rochester |
Method of identifying polypeptide monobodies which bind to target proteins and use thereof
|
|
AU2002236495B2
(en)
|
2000-11-29 |
2006-05-11 |
Allergan, Inc. |
Intraocular implants for preventing transplant rejection in the eye
|
|
US6509027B2
(en)
|
2001-02-12 |
2003-01-21 |
Supergen, Inc. |
Injectable pharmaceutical composition comprising coated particles of camptothecin
|
|
CA2443332A1
(en)
|
2001-04-04 |
2002-10-17 |
University Of Rochester |
.alpha..nu..beta.3 integrin-binding polypeptide monobodies and their use
|
|
DK1390535T3
(da)
|
2001-04-26 |
2010-12-06 |
Amgen Mountain View Inc |
Kombinatoriske biblioteker af monomer-domæner
|
|
US20030004561A1
(en)
|
2001-06-28 |
2003-01-02 |
Steve Bigus |
Peeling sheath for self-expanding stent
|
|
AU2002342672A1
(en)
|
2001-09-11 |
2003-03-24 |
Nascacell Gmbh |
Method for screening for inhibitors of protein/protein interaction and corresponding ribozymes
|
|
US20080193445A1
(en)
*
|
2002-01-18 |
2008-08-14 |
Liliane Goetsch |
Novel anti-IGF-IR antibodies and uses thereof
|
|
CA2662899A1
(en)
|
2002-02-22 |
2003-09-04 |
Schering Corporation |
Pharmaceutical formulations of antineoplastic agents, in particular temozolomide, processes of making and using the same
|
|
SI1916001T1
(sl)
|
2002-03-04 |
2011-10-28 |
Imclone Llc |
Äśloveĺ ka protitelesa specifiäśna za kdr in njihova uporaba
|
|
WO2003104418A2
(en)
|
2002-06-06 |
2003-12-18 |
Research Corporation Technologies, Inc. |
Reconstituted polypeptides
|
|
ES2655912T3
(es)
|
2002-11-08 |
2018-02-22 |
Ablynx N.V. |
Anticuerpos de dominio simple dirigidos contra factor de necrosis tumoral-alfa y usos para los mismos
|
|
US7053701B2
(en)
|
2003-11-04 |
2006-05-30 |
Vice Michael W |
Power amplifier output stage with multiple power states and improved efficiency
|
|
WO2005047714A1
(en)
|
2003-11-17 |
2005-05-26 |
Telezygology Inc |
Fasteners and other assemblies
|
|
CN1946417A
(zh)
*
|
2003-12-05 |
2007-04-11 |
阿德内克休斯治疗公司 |
2型血管内皮生长因子受体的抑制剂
|
|
US20080220049A1
(en)
|
2003-12-05 |
2008-09-11 |
Adnexus, A Bristol-Myers Squibb R&D Company |
Compositions and methods for intraocular delivery of fibronectin scaffold domain proteins
|
|
US20070059336A1
(en)
|
2004-04-30 |
2007-03-15 |
Allergan, Inc. |
Anti-angiogenic sustained release intraocular implants and related methods
|
|
US20050244469A1
(en)
|
2004-04-30 |
2005-11-03 |
Allergan, Inc. |
Extended therapeutic effect ocular implant treatments
|
|
WO2005110374A1
(en)
|
2004-04-30 |
2005-11-24 |
Allergan, Inc. |
Intraocular drug delivery systems containing a therapeutic component, a cyclodextrin, and a polymeric component
|
|
US20060182783A1
(en)
|
2004-04-30 |
2006-08-17 |
Allergan, Inc. |
Sustained release intraocular drug delivery systems
|
|
JP2008512352A
(ja)
|
2004-07-17 |
2008-04-24 |
イムクローン システムズ インコーポレイティド |
新規な四価の二重特異性抗体
|
|
US7597884B2
(en)
*
|
2004-08-09 |
2009-10-06 |
Alios Biopharma, Inc. |
Hyperglycosylated polypeptide variants and methods of use
|
|
BRPI0516308A2
(pt)
|
2004-10-04 |
2010-06-15 |
Qlt Usa Inc |
composição fluida, métodos de tratamento de uma doença ou disfunção, métodos de liberação local ou sistêmica de um agente biológico, implantes, método de formação de um implante, kit de agente biológico e usos de uma composição fluida
|
|
US20060122162A1
(en)
|
2004-12-02 |
2006-06-08 |
Schering Corporation |
Methods of using temozolomide formulation intrathecally in the treatment of cancers
|
|
CA2599606A1
(en)
|
2005-02-23 |
2006-08-31 |
Merrimack Pharmaceuticals, Inc. |
Bispecific binding agents for modulating biological activity
|
|
FR2888850B1
(fr)
|
2005-07-22 |
2013-01-11 |
Pf Medicament |
Nouveaux anticorps anti-igf-ir et leurs applications
|
|
US7612181B2
(en)
*
|
2005-08-19 |
2009-11-03 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
|
US7887273B2
(en)
|
2005-09-15 |
2011-02-15 |
Newfrey Llc |
Blind rivet and method
|
|
US20070072933A1
(en)
|
2005-09-26 |
2007-03-29 |
Peyman Gholam A |
Delivery of an ocular agent
|
|
WO2007044688A1
(en)
*
|
2005-10-07 |
2007-04-19 |
The Regents Of The University Of California |
Nucleic acids encoding modified cytochrome p450 enzymes and methods of use thereof
|
|
KR101430760B1
(ko)
|
2005-10-18 |
2014-08-19 |
알러간, 인코포레이티드 |
후안부 조직으로 선택적으로 침투하는 글루코코르티코이드유도체를 사용한 안과 요법
|
|
US20070099879A1
(en)
|
2005-10-31 |
2007-05-03 |
Wisconsin Alumni Research Foundation (Warf) |
Method of using calcitriol for treating intraocular diseases associated with angiogenesis
|
|
DE502005009389D1
(de)
|
2005-11-09 |
2010-05-20 |
Morphosys Ag |
Identifizierung und charakterisierung von funktionsblockierenden anti-ed-b-fibronektin antikörpern
|
|
KR20190006086A
(ko)
*
|
2005-11-23 |
2019-01-16 |
악셀레론 파마 인코포레이티드 |
액티빈-ａｃｔｒⅱａ 길항제 및 골 성장을 촉진하기 위한 이들의 용도
|
|
EP2397148A3
(en)
|
2006-02-02 |
2012-04-25 |
Allergan, Inc. |
Compositions and methods for the treatment of ophthalmic disease
|
|
EA014531B1
(ru)
*
|
2006-02-24 |
2010-12-30 |
КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. |
Антиамилоидные иммуногенные композиции, способы и применения
|
|
AU2007241405A1
(en)
*
|
2006-04-21 |
2007-11-01 |
Transgene S.A. |
HPV-18-based papillomavirus vaccine
|
|
US20070269422A1
(en)
|
2006-05-17 |
2007-11-22 |
Ablynx N.V. |
Serum albumin binding proteins with long half-lives
|
|
EP2054444B1
(en)
|
2006-08-04 |
2016-11-02 |
MedImmune Limited |
Antibodies to erbb2
|
|
WO2008031098A1
(en)
|
2006-09-09 |
2008-03-13 |
The University Of Chicago |
Binary amino acid libraries for fibronectin type iii polypeptide monobodies
|
|
US20110143953A1
(en)
*
|
2006-10-16 |
2011-06-16 |
Arizona Board Of Regents, A Body Corporate Of The State Of Arizona |
Synthetic Antibodies
|
|
CA2670471A1
(en)
|
2006-11-22 |
2008-06-05 |
Adnexus, A Bristol-Myers Squibb R&D Company (A Delaware Corporation) |
Targeted therapeutics based on engineered proteins for tyrosine kinases receptors, including igf-ir
|
|
US8476243B2
(en)
*
|
2006-12-29 |
2013-07-02 |
Transderm, Inc. |
Methods and compositions for treating keratin hyperproliferative disorders
|
|
US20100144599A1
(en)
*
|
2007-02-02 |
2010-06-10 |
Bristol-Myers Squibb Company |
Vegf pathway blockade
|
|
US20100166747A1
(en)
|
2007-03-02 |
2010-07-01 |
Beltran Pedro J |
Methods and compositions for treating tumor diseases
|
|
US11078262B2
(en)
|
2007-04-30 |
2021-08-03 |
Allergan, Inc. |
High viscosity macromolecular compositions for treating ocular conditions
|
|
EP2162540A2
(en)
|
2007-05-22 |
2010-03-17 |
Amgen Inc. |
Compositions and methods for producing bioactive fusion proteins
|
|
US8470966B2
(en)
|
2007-08-10 |
2013-06-25 |
Protelica, Inc. |
Universal fibronectin type III binding-domain libraries
|
|
US20090176654A1
(en)
|
2007-08-10 |
2009-07-09 |
Protelix, Inc. |
Universal fibronectin type III binding-domain libraries
|
|
US8680019B2
(en)
|
2007-08-10 |
2014-03-25 |
Protelica, Inc. |
Universal fibronectin Type III binding-domain libraries
|
|
US20100285000A1
(en)
*
|
2007-08-20 |
2010-11-11 |
Bristol-Myers Squibb Company |
Use of vegfr-2 inhibitors for treating metastatic cancer
|
|
KR101662622B1
(ko)
|
2007-10-04 |
2016-10-05 |
지모제넥틱스, 인코포레이티드 |
Ｂ7 패밀리 구성원 ｚＢ7Ｈ6 및 관련된 조성물 및 방법
|
|
EP2215246B1
(en)
|
2007-10-31 |
2015-01-07 |
MedImmune, LLC |
Protein scaffolds
|
|
EP2217274A1
(en)
|
2007-11-28 |
2010-08-18 |
Bristol-Myers Squibb Company |
Combination vegfr2 therapy with mtor inhibitors
|
|
WO2009086116A2
(en)
|
2007-12-19 |
2009-07-09 |
Centocor, Inc. |
Alternative scaffold protein fusions phage display via fusion to plx of m13 phage
|
|
JP2011507543A
(ja)
|
2007-12-27 |
2011-03-10 |
ノバルティス アーゲー |
改善されたフィブロネクチンベースの結合分子およびそれらの使用
|
|
CN102007145A
(zh)
|
2008-02-14 |
2011-04-06 |
百时美施贵宝公司 |
基于结合egfr的工程化蛋白质的靶向治疗剂
|
|
PL2274331T3
(pl)
|
2008-05-02 |
2014-04-30 |
Novartis Ag |
Ulepszone cząsteczki wiążące oparte na fibronektynie i ich zastosowanie
|
|
PE20091931A1
(es)
|
2008-05-22 |
2009-12-31 |
Bristol Myers Squibb Co |
Proteinas de dominio de armazon basadas en fibronectina multivalentes
|
|
BRPI0919881B1
(pt)
|
2008-10-31 |
2021-09-08 |
Centocor Ortho Biotech Inc |
Proteína de arcabouço e seu método de geração, biblioteca e seu método de construção, molécula de ácido nucleico, vetor de ácido nucleico, célula hospedeira, composição, dispositivo médico e artigo de fabricação
|
|
US8415291B2
(en)
|
2008-10-31 |
2013-04-09 |
Centocor Ortho Biotech Inc. |
Anti-TNF alpha fibronectin type III domain based scaffold compositions, methods and uses
|
|
TWI496582B
(zh)
|
2008-11-24 |
2015-08-21 |
必治妥美雅史谷比公司 |
雙重專一性之ｅｇｆｒ／ｉｇｆｉｒ結合分子
|
|
US20110275535A1
(en)
|
2008-12-16 |
2011-11-10 |
Novartis Ag |
Yeast Display Systems
|
|
WO2010093771A1
(en)
|
2009-02-11 |
2010-08-19 |
Bristol-Myers Squibb Company |
Combination vegfr2 therapy with temozolomide
|
|
BRPI1008532B1
(pt)
|
2009-02-12 |
2021-12-14 |
Janssen Biotech, Inc |
Arcabouço de proteína isolada, método para construção de uma biblioteca de arcabouço de proteína isolada, molécula de ácido nucleico isolada, vetor de ácido nucleico isolado, célula hospedeira de bactéria ou fungo, composição, dispositivo médico e artigo de manufatura para uso farmacêutico ou de diagnóstico em seres humanos
|
|
US8067201B2
(en)
*
|
2009-04-17 |
2011-11-29 |
Bristol-Myers Squibb Company |
Methods for protein refolding
|
|
EP2464663A4
(en)
|
2009-08-13 |
2013-05-29 |
Massachusetts Inst Technology |
MANIPULATED PROTEINS WITH MUTANT FIBRONECTIN DOMAINS
|
|
EP2494046B1
(en)
|
2009-10-30 |
2018-09-12 |
Novartis AG |
Universal fibronectin type iii bottom-side binding domain libraries
|
|
WO2011051466A1
(en)
|
2009-11-02 |
2011-05-05 |
Novartis Ag |
Anti-idiotypic fibronectin-based binding molecules and uses thereof
|
|
US20110123545A1
(en)
|
2009-11-24 |
2011-05-26 |
Bristol-Myers Squibb Company |
Combination of vegfr2 and igf1r inhibitors for the treatment of proliferative diseases
|
|
WO2011092233A1
(en)
|
2010-01-29 |
2011-08-04 |
Novartis Ag |
Yeast mating to produce high-affinity combinations of fibronectin-based binders
|
|
WO2011100700A2
(en)
|
2010-02-12 |
2011-08-18 |
University Of Rochester |
Antigenic mimics of discontinuous epitopes of pathogen recognized by broadly neutralizing antibodies
|
|
KR20130010461A
(ko)
|
2010-02-18 |
2013-01-28 |
브리스톨-마이어스 스큅 컴퍼니 |
Ｉｌ―２３에 결합하는 피브로넥틴 기반 스캐폴드 도메인 단백질
|
|
CA2795325A1
(en)
|
2010-04-13 |
2011-10-20 |
Medimmune, Llc |
Fibronectin type iii domain-based multimeric scaffolds
|
|
EA022983B1
(ru)
|
2010-04-13 |
2016-04-29 |
Бристол-Майерс Сквибб Компани |
Белки на основе структурного домена фибронектина, связывающие pcsk9
|
|
EP3569256B1
(en)
|
2010-04-30 |
2022-06-15 |
Janssen Biotech, Inc. |
Stabilized fibronectin domain compositions, methods and uses
|
|
TW201138808A
(en)
|
2010-05-03 |
2011-11-16 |
Bristol Myers Squibb Co |
Serum albumin binding molecules
|
|
ES2573108T3
(es)
*
|
2010-05-26 |
2016-06-06 |
Bristol-Myers Squibb Company |
Proteínas de armazón a base de fibronectina que tienen estabilidad mejorada
|
|
CN107903321A
(zh)
|
2010-07-30 |
2018-04-13 |
诺华有限公司 |
纤连蛋白摇篮分子和其库
|
|
JP2014504587A
(ja)
|
2010-12-22 |
2014-02-24 |
ブリストル−マイヤーズ スクイブ カンパニー |
Ｉｌ−２３に結合するフィブロネクチンをベースとするスカフォールドドメインタンパク質
|
|
RS55609B1
(sr)
|
2011-04-13 |
2017-06-30 |
Bristol Myers Squibb Co |
Fc fuzioni proteini koji sadrže nove linkere ili aranžmane
|
|
EP2709669A1
(en)
|
2011-05-17 |
2014-03-26 |
Bristol-Myers Squibb Company |
Methods for maintaining pegylation of polypeptides
|
|
EP3318880B1
(en)
|
2011-05-17 |
2020-12-16 |
Bristol-Myers Squibb Company |
Improved methods for the selection of binding proteins
|
|
EP2761066B1
(en)
|
2011-09-27 |
2018-12-05 |
Janssen Biotech, Inc. |
Fibronectin type iii repeat based protein scaffolds with alternative binding surfaces
|