JP2019516665A5 - - Google Patents
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- Publication number
- JP2019516665A5 JP2019516665A5 JP2018546587A JP2018546587A JP2019516665A5 JP 2019516665 A5 JP2019516665 A5 JP 2019516665A5 JP 2018546587 A JP2018546587 A JP 2018546587A JP 2018546587 A JP2018546587 A JP 2018546587A JP 2019516665 A5 JP2019516665 A5 JP 2019516665A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- terminal
- mhc
- multimeric
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662302654P | 2016-03-02 | 2016-03-02 | |
| US62/302,654 | 2016-03-02 | ||
| PCT/US2017/020276 WO2017151818A2 (en) | 2016-03-02 | 2017-03-01 | T-cell modulatory multimeric polypeptides and methods of use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019516665A JP2019516665A (ja) | 2019-06-20 |
| JP2019516665A5 true JP2019516665A5 (https=) | 2020-04-09 |
Family
ID=59743228
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018546587A Pending JP2019516665A (ja) | 2016-03-02 | 2017-03-01 | Ｔ細胞調節多量体ポリペプチド及びその使用方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20190062400A1 (https=) |
| EP (1) | EP3423108A4 (https=) |
| JP (1) | JP2019516665A (https=) |
| KR (1) | KR20180132663A (https=) |
| CN (1) | CN109311945A (https=) |
| AU (1) | AU2017226269B2 (https=) |
| CA (1) | CA3014458A1 (https=) |
| IL (1) | IL261401A (https=) |
| WO (1) | WO2017151818A2 (https=) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2894511C (en) | 2012-12-11 | 2021-12-07 | Albert Einstein College Of Medicine Of Yeshiva University | Methods for high throughput receptor:ligand identification |
| CN121159719A (zh) | 2015-04-17 | 2025-12-19 | 高山免疫科学股份有限公司 | 具有可调的亲和力的免疫调节蛋白 |
| US10273281B2 (en) | 2015-11-02 | 2019-04-30 | Five Prime Therapeutics, Inc. | CD80 extracellular domain polypeptides and their use in cancer treatment |
| WO2017181152A2 (en) | 2016-04-15 | 2017-10-19 | Alpine Immune Sciences, Inc. | Cd80 variant immunomodulatory proteins and uses thereof |
| CN109689096A (zh) | 2016-05-18 | 2019-04-26 | 阿尔伯特爱因斯坦医学院公司 | 变体pd-l1多肽、t细胞调节性多聚体多肽及其使用方法 |
| WO2017201210A1 (en) | 2016-05-18 | 2017-11-23 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
| ES2973548T3 (es) | 2016-12-22 | 2024-06-20 | Cue Biopharma Inc | Polipéptidos multiméricos moduladores de linfocitos T y métodos para su uso |
| EP3565829A4 (en) | 2017-01-09 | 2021-01-27 | Cue Biopharma, Inc. | T-CELL-MODULATING MULTIMERIC POLYPEPTIDES AND METHOD OF USING THEREOF |
| US20200010528A1 (en) | 2017-03-15 | 2020-01-09 | Cue Biopharma, Inc. | Methods for modulating an immune response |
| SG11201907769XA (en) | 2017-03-16 | 2019-09-27 | Alpine Immune Sciences Inc | Cd80 variant immunomodulatory proteins and uses thereof |
| KR20190139216A (ko) | 2017-04-28 | 2019-12-17 | 파이브 프라임 테라퓨틱스, 인크. | Cd80 세포외 도메인 폴리펩티드를 이용한 치료 방법 |
| JP2020534352A (ja) * | 2017-09-07 | 2020-11-26 | キュー バイオファーマ，インコーポレーテッド | コンジュゲーション部位を有するｔ細胞調節多量体ポリペプチド及びその使用方法 |
| EP3678677A4 (en) * | 2017-09-07 | 2021-06-16 | Cue Biopharma, Inc. | Antigen-presenting polypeptides and methods of use thereof |
| CN111886241A (zh) | 2018-01-09 | 2020-11-03 | 库尔生物制药有限公司 | 多聚体t细胞调节多肽及其使用方法 |
| EP3897690A4 (en) * | 2018-12-19 | 2022-09-28 | Cue Biopharma, Inc. | T LYMPHOCYTE MODULATOR MULTIMERIC POLYPEPTIDES HAVING CONJUGATION SITES AND METHODS OF USE THEREOF |
| US12589132B2 (en) | 2019-02-22 | 2026-03-31 | Five Prime Therapeutics, Inc. | CD80 extracellular domain Fc fusion proteins for treating PD-L1 negative tumors |
| WO2020181272A1 (en) * | 2019-03-06 | 2020-09-10 | Cue Biopharma, Inc. | Antigen-presenting polypeptides with chemical conjugation sites and methods of use thereof |
| KR20220015382A (ko) * | 2019-05-29 | 2022-02-08 | 큐 바이오파마, 인크. | 다량체 t-세포 조절 폴리펩타이드 및 이의 사용 방법 |
| CA3146591A1 (en) * | 2019-09-20 | 2021-03-25 | Ronald D. Seidel Iii | T-cell modulatory polypeptides and methods of use thereof |
| DK4034170T3 (da) | 2019-10-23 | 2026-03-30 | Cue Biopharma Inc | Tgf-beta-polypeptider |
| US20230126784A1 (en) * | 2020-03-06 | 2023-04-27 | Albert Einstein College Of Medicine | A method to generate chimeric antigen receptor (car) t-cells (car-t cells) from pathogen-specific cytotoxic lymphocytes to enable the subsequent in vivo modulation of their functional activity |
| EP4118105A2 (en) * | 2020-03-09 | 2023-01-18 | Pfizer Inc. | Cd80-fc fusion protein and uses thereof |
| WO2021231376A2 (en) | 2020-05-12 | 2021-11-18 | Cue Biopharma, Inc. | Multimeric t-cell modulatory polypeptides and methods of use thereof |
| US20230218731A1 (en) * | 2020-05-26 | 2023-07-13 | Cue Biopharma, Inc. | Antigen Presenting Polypeptide Complexes and Methods of Use Thereof |
| WO2021242935A1 (en) * | 2020-05-26 | 2021-12-02 | Cue Biopharma, Inc. | Antigen presenting polypeptide complexes and methods of use thereof |
| IL299834A (en) * | 2020-07-14 | 2023-03-01 | Cue Biopharma Inc | with binding sites and methods for using them T - cellular modulatory polypeptides |
| WO2022056014A1 (en) | 2020-09-09 | 2022-03-17 | Cue Biopharma, Inc. | Mhc class ii t-cell modulatory multimeric polypeptides for treating type 1 diabetes mellitus (t1d) and methods of use thereof |
| CA3216273A1 (en) * | 2021-04-21 | 2022-10-27 | Ronald D. SEIDEL III | Antigen presenting polypeptide complexes bearing tgf-beta and methods of use thereof |
| WO2022251552A2 (en) * | 2021-05-26 | 2022-12-01 | Cue Biopharma, Inc. | Antigen presenting polypeptide complexes and methods of use thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL202844B1 (pl) * | 1998-04-07 | 2009-07-31 | Corixa Corp | Immunogeniczny polipeptyd, polinukleotyd, polipeptyd, kompozycja farmaceutyczna, wektor ekspresji, kompozycja szczepionki, polipeptyd do stosowania w leczeniu lub zapobieganiu infekcjom Mycobacterium tuberculosis, polinukleotyd do stosowania w leczeniu lub zapobieganiu infekcjom Mycobacterium tuberculosis i sposób wytwarzania polipeptydu |
| CN103796681B (zh) * | 2011-06-30 | 2018-07-20 | 建新公司 | T细胞活化的抑制剂 |
| CN102898504B (zh) * | 2012-10-23 | 2014-08-06 | 中国农业大学 | 抗氧化活性合成肽及其用途 |
| WO2015195531A2 (en) * | 2014-06-18 | 2015-12-23 | Albert Einstein College Of Medicine, Inc. | Syntac polypeptides and uses thereof |
-
2017
- 2017-03-01 WO PCT/US2017/020276 patent/WO2017151818A2/en not_active Ceased
- 2017-03-01 CA CA3014458A patent/CA3014458A1/en not_active Abandoned
- 2017-03-01 AU AU2017226269A patent/AU2017226269B2/en not_active Expired - Fee Related
- 2017-03-01 KR KR1020187028428A patent/KR20180132663A/ko not_active Ceased
- 2017-03-01 JP JP2018546587A patent/JP2019516665A/ja active Pending
- 2017-03-01 CN CN201780027232.8A patent/CN109311945A/zh active Pending
- 2017-03-01 US US16/077,420 patent/US20190062400A1/en not_active Abandoned
- 2017-03-01 EP EP17760749.6A patent/EP3423108A4/en not_active Withdrawn
-
2018
- 2018-08-27 IL IL261401A patent/IL261401A/en unknown
-
2022
- 2022-08-12 US US17/887,199 patent/US20230227530A1/en active Pending
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