JP2015520752A - Ｎａｍｐｔ阻害薬としてのピリダジンおよびピリジン誘導体 - Google Patents

Ｎａｍｐｔ阻害薬としてのピリダジンおよびピリジン誘導体 Download PDF

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JP2015520752A
JP2015520752A JP2015511730A JP2015511730A JP2015520752A JP 2015520752 A JP2015520752 A JP 2015520752A JP 2015511730 A JP2015511730 A JP 2015511730A JP 2015511730 A JP2015511730 A JP 2015511730A JP 2015520752 A JP2015520752 A JP 2015520752A
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carboxamide
phenyl
pyridazin
azetidine
piperidin
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JP2015520752A5 (cg-RX-API-DMAC7.html
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ハンセン，トッド・エム
ロングネッカー，ケントン
ヘイマン，ハワード・アール
カーティン，マイケル・エル
クラーク，リチャード・エフ
ソーレンセン，ブライアン
ジー，ジーチン
ドハーティ，ジョージ
フレイ，ロビン
ウォーラー，ケビン
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アッヴィ・インコーポレイテッド
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
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  • Virology (AREA)
  • Biomedical Technology (AREA)
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  • AIDS & HIV (AREA)
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JP2015511730A 2012-05-11 2013-05-10 Ｎａｍｐｔ阻害薬としてのピリダジンおよびピリジン誘導体 Pending JP2015520752A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201261645692P 2012-05-11 2012-05-11
US61/645,692 2012-05-11
US201261719013P 2012-10-26 2012-10-26
US61/719,013 2012-10-26
US201361779756P 2013-03-13 2013-03-13
US61/779,756 2013-03-13
PCT/US2013/040481 WO2013170115A1 (en) 2012-05-11 2013-05-10 Pyridazine and pyridine derivatives as nampt inhibitors

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JP2015520752A true JP2015520752A (ja) 2015-07-23
JP2015520752A5 JP2015520752A5 (cg-RX-API-DMAC7.html) 2016-06-30

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US (4) US8975398B2 (cg-RX-API-DMAC7.html)
EP (1) EP2847181A1 (cg-RX-API-DMAC7.html)
JP (1) JP2015520752A (cg-RX-API-DMAC7.html)
CN (1) CN104583194A (cg-RX-API-DMAC7.html)
AR (1) AR091023A1 (cg-RX-API-DMAC7.html)
CA (1) CA2873097A1 (cg-RX-API-DMAC7.html)
HK (1) HK1209739A1 (cg-RX-API-DMAC7.html)
MX (1) MX2014013751A (cg-RX-API-DMAC7.html)
TW (1) TW201350478A (cg-RX-API-DMAC7.html)
UY (1) UY34804A (cg-RX-API-DMAC7.html)
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