JP2015516420A5 - - Google Patents

Download PDF

Info

Publication number
JP2015516420A5
JP2015516420A5 JP2015511546A JP2015511546A JP2015516420A5 JP 2015516420 A5 JP2015516420 A5 JP 2015516420A5 JP 2015511546 A JP2015511546 A JP 2015511546A JP 2015511546 A JP2015511546 A JP 2015511546A JP 2015516420 A5 JP2015516420 A5 JP 2015516420A5
Authority
JP
Japan
Prior art keywords
optionally substituted
fluoro
pharmaceutically acceptable
acceptable salt
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2015511546A
Other languages
English (en)
Japanese (ja)
Other versions
JP2015516420A (ja
JP6178843B2 (ja
Filing date
Publication date
Priority claimed from PCT/CN2012/075185 external-priority patent/WO2013166654A1/en
Application filed filed Critical
Priority claimed from PCT/US2013/039377 external-priority patent/WO2013169576A1/en
Publication of JP2015516420A publication Critical patent/JP2015516420A/ja
Publication of JP2015516420A5 publication Critical patent/JP2015516420A5/ja
Application granted granted Critical
Publication of JP6178843B2 publication Critical patent/JP6178843B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2015511546A 2012-05-08 2013-05-03 透過性グリコシダーゼインヒビターおよびその用途 Expired - Fee Related JP6178843B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CNPCT/CN2012/075185 2012-05-08
PCT/CN2012/075185 WO2013166654A1 (en) 2012-05-08 2012-05-08 Permeable glycosidase inhibitors and uses thereof
US201261655641P 2012-06-05 2012-06-05
US61/655,641 2012-06-05
PCT/US2013/039377 WO2013169576A1 (en) 2012-05-08 2013-05-03 Permeable glycosidase inhibitors and uses thereof

Publications (3)

Publication Number Publication Date
JP2015516420A JP2015516420A (ja) 2015-06-11
JP2015516420A5 true JP2015516420A5 (enExample) 2016-06-23
JP6178843B2 JP6178843B2 (ja) 2017-08-09

Family

ID=49551168

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015511546A Expired - Fee Related JP6178843B2 (ja) 2012-05-08 2013-05-03 透過性グリコシダーゼインヒビターおよびその用途

Country Status (10)

Country Link
US (1) US9611275B2 (enExample)
EP (1) EP2847199B1 (enExample)
JP (1) JP6178843B2 (enExample)
KR (1) KR102108586B1 (enExample)
CN (1) CN104395323B (enExample)
AU (1) AU2013259892B2 (enExample)
BR (1) BR112014027724B1 (enExample)
CA (1) CA2871920C (enExample)
RU (1) RU2707292C2 (enExample)
WO (1) WO2013169576A1 (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9079868B2 (en) 2008-08-01 2015-07-14 Simon Fraser University Selective glycosidase inhibitors and uses thereof
US9120781B2 (en) 2010-05-11 2015-09-01 Simon Fraser University Selective glycosidase inhibitors and uses thereof
EP2638052B1 (en) 2010-11-08 2017-03-22 Alectos Therapeutics, Inc. Selective glycosidase inhibitors and uses thereof
PL2655388T3 (pl) 2010-12-23 2016-12-30 Selektywne inhibitory glikozydazy i ich zastosowania
WO2012126091A1 (en) 2011-03-24 2012-09-27 Alectos Therapeutics Inc. Selective glycosidase inhibitors and uses thereof
US9718854B2 (en) 2011-03-31 2017-08-01 Alectos Therapeutics Inc. Selective glycosidase inhibitors and uses thereof
EP2726492B1 (en) 2011-06-27 2017-11-01 Alectos Therapeutics Inc. Selective glycosidase inhibitors and uses thereof
US9199949B2 (en) 2011-06-27 2015-12-01 Alectos Therapeutics Inc. Selective glycosidase inhibitors and uses thereof
US9409924B2 (en) 2011-06-27 2016-08-09 Alectos Therapeutics Inc. Selective glycosidase inhibitors and uses thereof
WO2014032185A1 (en) 2012-08-31 2014-03-06 Alectos Therapeutics Inc. Glycosidase inhibitors and uses thereof
WO2014032188A1 (en) 2012-08-31 2014-03-06 Alectos Therapeutics Inc. Glycosidase inhibitors and uses thereof
RU2672873C2 (ru) 2012-10-31 2018-11-20 Алектос Терапьютикс Инк. Ингибиторы гликозидаз и их применения
WO2014100934A1 (en) 2012-12-24 2014-07-03 Merck Sharp & Dohme Corp. Glycosidase inhibitors and uses thereof
DK3008168T3 (da) 2013-06-11 2020-05-04 Harvard College Sc-celler og sammensætninger og fremgangsmåde til dannelse deraf
CA2966620A1 (en) 2014-11-05 2016-05-12 Voyager Therapeutics, Inc. Aadc polynucleotides for the treatment of parkinson's disease
CA2975583A1 (en) 2014-11-14 2016-05-19 Voyager Therapeutics, Inc. Modulatory polynucleotides
KR20220108216A (ko) 2016-05-18 2022-08-02 보이저 테라퓨틱스, 인크. 헌팅톤 질환을 치료하기 위한 조성물 및 방법
KR20240056729A (ko) 2016-05-18 2024-04-30 보이저 테라퓨틱스, 인크. 조절성 폴리뉴클레오티드
SG11201909868YA (en) 2017-05-05 2019-11-28 Voyager Therapeutics Inc Compositions and methods of treating huntington's disease
JOP20190269A1 (ar) 2017-06-15 2019-11-20 Voyager Therapeutics Inc بولي نوكليوتيدات aadc لعلاج مرض باركنسون
MX2020012077A (es) 2018-05-15 2021-03-09 Voyager Therapeutics Inc Composiciones y metodos para el tratamiento de la enfermedad de parkinson.
CN110407674A (zh) * 2018-08-14 2019-11-05 重庆市化工研究院 4-烯丙氧基苯甲醇、合成方法及应用
CN116916916A (zh) * 2020-09-25 2023-10-20 塞维利亚大学 糖苷酶抑制剂及其用途

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1441749A1 (ru) * 1987-03-16 1996-01-10 Институт Тонкой Органической Химии Им.А.Л.Мнджояна 2-АМИНО-5,5-ДИМЕТИЛ-4,5-ДИГИДРО-7Н-ПИРАНО [4,3-d] ТИАЗОЛ, ОБЛАДАЮЩИЙ ТРАНКВИЛИЗИРУЮЩЕЙ АКТИВНОСТЬЮ
EP1734821A4 (en) 2004-04-14 2011-07-06 Uab Research Foundation ACTIVATORS OF HEXOSAMIN BINOSYNTHESIS AS AN INHIBITORS FOR INDUCED DAMAGE CAUSED BY ISCHEMIC SHOCK OR HEMORRHAGIC SHOCK
AU2006220187B2 (en) * 2005-03-01 2012-11-08 Simon Fraser University Selective glycosidase inhibitors, methods of making inhibitors, and uses thereof
EP2057171A4 (en) * 2006-08-31 2010-04-21 Univ Fraser Simon SELECTIVE GLYCOSIDASE INHIBITORS AND APPLICATIONS THEREOF
CN107253970A (zh) * 2006-08-31 2017-10-17 西蒙·弗雷瑟大学 选择性糖苷酶抑制剂及其用途
US9079868B2 (en) 2008-08-01 2015-07-14 Simon Fraser University Selective glycosidase inhibitors and uses thereof
WO2010012106A1 (en) 2008-08-01 2010-02-04 Simon Fraser University Selective glycosidase inhibitors and uses thereof
US20110301217A1 (en) 2008-09-16 2011-12-08 David Jaro Vocadlo Selective Glycosidase Inhibitors and Uses Thereof
US9120781B2 (en) * 2010-05-11 2015-09-01 Simon Fraser University Selective glycosidase inhibitors and uses thereof
WO2012061972A1 (en) * 2010-11-08 2012-05-18 Alectos Therapeutics Inc. Selective glycosidase inhibitors and uses thereof
TW201249848A (en) * 2010-11-08 2012-12-16 Merck Sharp & Dohme Selective glycosidase inhibitors and uses thereof
WO2012159262A1 (en) * 2011-05-24 2012-11-29 Alectos Therapeutics Inc. Selective glycosidase inhibitors and uses thereof
WO2013025452A1 (en) * 2011-08-18 2013-02-21 Merck Sharp & Dohme Corp. Selective glycosidase inhibitors and uses thereof

Similar Documents

Publication Publication Date Title
JP2015516420A5 (enExample)
RU2014149183A (ru) Проницаемые ингибиторы гликозидазы и их применения
JP2013533253A5 (enExample)
JP2019518766A5 (enExample)
JP2012510502A5 (enExample)
PE20230834A1 (es) Antagonistas del receptor de lpa y usos de los mismos
EP4328223A3 (en) Substituted diaminocarboxamide and diaminocarbonitrile pyrimidines, compositions thereof, and methods of treatment therewith
JP2013525458A5 (enExample)
JP2014508811A5 (enExample)
JP2015537020A5 (enExample)
EA201590345A1 (ru) Способы лечения рака с использованием 3-(4-((4-(морфолинометил)бензил)окси)-1-оксоизоиндолин-2-ил)пиперидин-2,6-диона
JP2011517453A5 (enExample)
NZ631477A (en) Substituted pyrrolidine-2-carboxamides
JP2013523733A5 (enExample)
JP2020527175A5 (enExample)
PH12014500775A1 (en) Ethynyl derivatives as mglur5 allosteric modulators
JP2013536188A5 (enExample)
RU2013140169A (ru) Противоопухолевое терапевтическое средство
JP2012518634A5 (enExample)
MX2013009709A (es) Derivados de heteroarilo como moduladores de nachr alfa 7.
PH12013501895A1 (en) Ethynyl derivatives as positive allosteric modulators of the mglur5
JP2014505017A5 (enExample)
JP2013542267A5 (enExample)
MX2016008536A (es) Derivados de fluoro-naftilo.
BR112013021848A2 (pt) 5-(fenil/piridinil-etinil)-2-piridina/2-pirimidina-carboxamidas como moduladores de mglur5