JP2015516420A5 - - Google Patents
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- Publication number
- JP2015516420A5 JP2015516420A5 JP2015511546A JP2015511546A JP2015516420A5 JP 2015516420 A5 JP2015516420 A5 JP 2015516420A5 JP 2015511546 A JP2015511546 A JP 2015511546A JP 2015511546 A JP2015511546 A JP 2015511546A JP 2015516420 A5 JP2015516420 A5 JP 2015516420A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally substituted
- fluoro
- pharmaceutically acceptable
- acceptable salt
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CN2012/075185 WO2013166654A1 (en) | 2012-05-08 | 2012-05-08 | Permeable glycosidase inhibitors and uses thereof |
| CNPCT/CN2012/075185 | 2012-05-08 | ||
| US201261655641P | 2012-06-05 | 2012-06-05 | |
| US61/655,641 | 2012-06-05 | ||
| PCT/US2013/039377 WO2013169576A1 (en) | 2012-05-08 | 2013-05-03 | Permeable glycosidase inhibitors and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015516420A JP2015516420A (ja) | 2015-06-11 |
| JP2015516420A5 true JP2015516420A5 (enExample) | 2016-06-23 |
| JP6178843B2 JP6178843B2 (ja) | 2017-08-09 |
Family
ID=49551168
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015511546A Expired - Fee Related JP6178843B2 (ja) | 2012-05-08 | 2013-05-03 | 透過性グリコシダーゼインヒビターおよびその用途 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9611275B2 (enExample) |
| EP (1) | EP2847199B1 (enExample) |
| JP (1) | JP6178843B2 (enExample) |
| KR (1) | KR102108586B1 (enExample) |
| CN (1) | CN104395323B (enExample) |
| AU (1) | AU2013259892B2 (enExample) |
| BR (1) | BR112014027724B1 (enExample) |
| CA (1) | CA2871920C (enExample) |
| RU (1) | RU2707292C2 (enExample) |
| WO (1) | WO2013169576A1 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2732336A1 (en) | 2008-08-01 | 2010-02-04 | Simon Fraser University | Selective glycosidase inhibitors and uses thereof |
| US9120781B2 (en) | 2010-05-11 | 2015-09-01 | Simon Fraser University | Selective glycosidase inhibitors and uses thereof |
| WO2012061927A1 (en) | 2010-11-08 | 2012-05-18 | Alectos Therapeutics, Inc. | Selective glycosidase inhibitors and uses thereof |
| TWI572609B (zh) | 2010-12-23 | 2017-03-01 | 默沙東藥廠 | 選擇性醣苷酶抑制劑及其用途 |
| WO2012126091A1 (en) | 2011-03-24 | 2012-09-27 | Alectos Therapeutics Inc. | Selective glycosidase inhibitors and uses thereof |
| EP2691407B1 (en) | 2011-03-31 | 2017-02-22 | Alectos Therapeutics Inc. | Selective glycosidase inhibitors and uses thereof |
| US9701693B2 (en) | 2011-06-27 | 2017-07-11 | Alectos Therapeutics Inc. | Selective glycosidase inhibitors and uses thereof |
| EP2723753B1 (en) | 2011-06-27 | 2017-08-02 | Alectos Therapeutics Inc. | Selective glycosidase inhibitors and uses thereof |
| US9199949B2 (en) | 2011-06-27 | 2015-12-01 | Alectos Therapeutics Inc. | Selective glycosidase inhibitors and uses thereof |
| EP2890675A4 (en) | 2012-08-31 | 2016-01-13 | Alectos Therapeutics Inc | GLYCOSIDASE INHIBITORS AND USES THEREOF |
| WO2014032185A1 (en) | 2012-08-31 | 2014-03-06 | Alectos Therapeutics Inc. | Glycosidase inhibitors and uses thereof |
| RU2672873C2 (ru) | 2012-10-31 | 2018-11-20 | Алектос Терапьютикс Инк. | Ингибиторы гликозидаз и их применения |
| WO2014100934A1 (en) | 2012-12-24 | 2014-07-03 | Merck Sharp & Dohme Corp. | Glycosidase inhibitors and uses thereof |
| KR102232650B1 (ko) | 2013-06-11 | 2021-03-29 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | SC-β 세포 및 조성물 그리고 그 생성 방법 |
| CN112553229A (zh) | 2014-11-05 | 2021-03-26 | 沃雅戈治疗公司 | 用于治疗帕金森病的aadc多核苷酸 |
| MX2017006217A (es) | 2014-11-14 | 2018-05-02 | Voyager Therapeutics Inc | Polinucleotidos moduladores. |
| AU2017267665C1 (en) | 2016-05-18 | 2023-10-05 | Voyager Therapeutics, Inc. | Modulatory polynucleotides |
| BR112018073472A2 (pt) | 2016-05-18 | 2019-08-27 | Voyager Therapeutics, Inc. | composições e métodos de tratamento da doença de huntington |
| CN111108198A (zh) | 2017-05-05 | 2020-05-05 | 沃雅戈治疗公司 | 治疗亨廷顿病的组合物和方法 |
| JOP20190269A1 (ar) | 2017-06-15 | 2019-11-20 | Voyager Therapeutics Inc | بولي نوكليوتيدات aadc لعلاج مرض باركنسون |
| AU2019268330A1 (en) | 2018-05-15 | 2020-11-26 | Voyager Therapeutics, Inc. | Compositions and methods for the treatment of Parkinson's disease |
| CN110407674A (zh) * | 2018-08-14 | 2019-11-05 | 重庆市化工研究院 | 4-烯丙氧基苯甲醇、合成方法及应用 |
| AU2021350590A1 (en) * | 2020-09-25 | 2023-04-27 | Consejo Superior De Investigaciones Cientificas (Csic) - Spanish National Research Council (Csic) | Glycosidase inhibitors and uses thereof |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU1441749A1 (ru) * | 1987-03-16 | 1996-01-10 | Институт Тонкой Органической Химии Им.А.Л.Мнджояна | 2-АМИНО-5,5-ДИМЕТИЛ-4,5-ДИГИДРО-7Н-ПИРАНО [4,3-d] ТИАЗОЛ, ОБЛАДАЮЩИЙ ТРАНКВИЛИЗИРУЮЩЕЙ АКТИВНОСТЬЮ |
| WO2006016904A2 (en) | 2004-04-14 | 2006-02-16 | Uab Research Foundation | Activators of hexosamine biosynthesis as inhibitors of injury induced by ischemia or hemorrhagic shock |
| CA2599843C (en) * | 2005-03-01 | 2013-08-27 | Simon Fraser University | Selective glycosidase inhibitors, methods of making inhibitors, and uses thereof |
| CN101595111A (zh) * | 2006-08-31 | 2009-12-02 | 西蒙·弗雷瑟大学 | 选择性糖苷酶抑制剂及其用途 |
| US8334310B2 (en) * | 2006-08-31 | 2012-12-18 | Simon Fraser University | Selective glycosidase inhibitors and uses thereof |
| US8541441B2 (en) | 2008-08-01 | 2013-09-24 | Simon Fraser University | Selective glycosidase inhibitors and uses thereof |
| CA2732336A1 (en) | 2008-08-01 | 2010-02-04 | Simon Fraser University | Selective glycosidase inhibitors and uses thereof |
| AU2009299073B2 (en) | 2008-09-16 | 2015-04-02 | Simon Fraser University | Selective glycosidase inhibitors and uses thereof |
| US9120781B2 (en) * | 2010-05-11 | 2015-09-01 | Simon Fraser University | Selective glycosidase inhibitors and uses thereof |
| WO2012061972A1 (en) * | 2010-11-08 | 2012-05-18 | Alectos Therapeutics Inc. | Selective glycosidase inhibitors and uses thereof |
| TW201249848A (en) * | 2010-11-08 | 2012-12-16 | Merck Sharp & Dohme | Selective glycosidase inhibitors and uses thereof |
| WO2012159262A1 (en) | 2011-05-24 | 2012-11-29 | Alectos Therapeutics Inc. | Selective glycosidase inhibitors and uses thereof |
| US9126957B2 (en) | 2011-08-18 | 2015-09-08 | Merck Sharp & Dohme Corp. | Selective glycosidase inhibitors and uses thereof |
-
2013
- 2013-05-03 JP JP2015511546A patent/JP6178843B2/ja not_active Expired - Fee Related
- 2013-05-03 KR KR1020147031131A patent/KR102108586B1/ko not_active Expired - Fee Related
- 2013-05-03 WO PCT/US2013/039377 patent/WO2013169576A1/en not_active Ceased
- 2013-05-03 BR BR112014027724-9A patent/BR112014027724B1/pt not_active IP Right Cessation
- 2013-05-03 AU AU2013259892A patent/AU2013259892B2/en not_active Ceased
- 2013-05-03 CN CN201380023214.4A patent/CN104395323B/zh not_active Expired - Fee Related
- 2013-05-03 US US14/399,146 patent/US9611275B2/en not_active Expired - Fee Related
- 2013-05-03 RU RU2014149183A patent/RU2707292C2/ru active
- 2013-05-03 EP EP13787989.6A patent/EP2847199B1/en active Active
- 2013-05-03 CA CA2871920A patent/CA2871920C/en active Active
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