JP2012510502A5 - - Google Patents
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- Publication number
- JP2012510502A5 JP2012510502A5 JP2011538999A JP2011538999A JP2012510502A5 JP 2012510502 A5 JP2012510502 A5 JP 2012510502A5 JP 2011538999 A JP2011538999 A JP 2011538999A JP 2011538999 A JP2011538999 A JP 2011538999A JP 2012510502 A5 JP2012510502 A5 JP 2012510502A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- pyrrolidine
- compound represented
- ethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08170435.5 | 2008-12-02 | ||
| EP08170435A EP2194048A1 (en) | 2008-12-02 | 2008-12-02 | Nitrate esters for the treatment of vascular and metabolic diseases |
| PCT/EP2009/066159 WO2010063724A1 (en) | 2008-12-02 | 2009-12-01 | Nitrate derivatives of cilostazol for the treatment of vascular and metabolic diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012510502A JP2012510502A (ja) | 2012-05-10 |
| JP2012510502A5 true JP2012510502A5 (enExample) | 2013-01-24 |
Family
ID=40456966
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011538999A Ceased JP2012510502A (ja) | 2008-12-02 | 2009-12-01 | 血管性及び代謝性疾患の処置のためのシロスタゾールの硝酸エステル誘導体 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8426597B2 (enExample) |
| EP (2) | EP2194048A1 (enExample) |
| JP (1) | JP2012510502A (enExample) |
| KR (1) | KR20110088598A (enExample) |
| CN (1) | CN102245583A (enExample) |
| AU (1) | AU2009324123A1 (enExample) |
| BR (1) | BRPI0923300A2 (enExample) |
| CA (1) | CA2745252A1 (enExample) |
| IL (1) | IL213214A0 (enExample) |
| MX (1) | MX2011005744A (enExample) |
| RU (1) | RU2011126607A (enExample) |
| SG (1) | SG171423A1 (enExample) |
| WO (1) | WO2010063724A1 (enExample) |
| ZA (1) | ZA201104011B (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20130075740A (ko) | 2010-04-19 | 2013-07-05 | 카르디올린크스 아게 | 혈관 질환 및 대사성 질환을 치료하기 위한 산화질소 공여체를 갖는 발사르탄 유도체 |
| TW201204355A (en) | 2010-06-02 | 2012-02-01 | Cardiolynx Ag | Nitrate derivatives of pioglitazone |
| CA2882489A1 (en) | 2012-08-21 | 2014-02-27 | Ortho-Clinical Diagnostics, Inc. | Antibodies to paliperidone haptens and use thereof |
| CN104755093B (zh) | 2012-08-21 | 2018-11-16 | 詹森药业有限公司 | 奥氮平半抗原的抗体及其用途 |
| WO2014031668A2 (en) | 2012-08-21 | 2014-02-27 | Ortho-Clinical Diagnostics, Inc | Antibodies to quetiapine and use thereof |
| TR201816416T4 (tr) | 2012-08-21 | 2018-11-21 | Janssen Pharmaceutica Nv | Risperidona yönelik antikorlar ve bunların kullanımı. |
| JP6374387B2 (ja) | 2012-08-21 | 2018-08-15 | ヤンセン ファーマシューティカ エヌ．ベー． | リスペリドンハプテンへの抗体及びその使用 |
| EP3492473B1 (en) | 2012-08-21 | 2025-07-30 | Janssen Pharmaceutica NV | Haptens of olanzapine |
| ES2762105T3 (es) | 2012-08-21 | 2020-05-22 | Janssen Pharmaceutica Nv | Anticuerpos para aripiprazol y uso de los mismos |
| AU2013305965B2 (en) | 2012-08-21 | 2017-08-24 | Saladax Biomedical Inc. | Antibodies to paliperidone and use thereof |
| PT3663317T (pt) | 2012-08-21 | 2023-01-23 | Janssen Pharmaceutica Nv | Anticorpos para haptenos de quetiapina e sua utilização |
| TR201809424T4 (tr) | 2012-08-21 | 2018-07-23 | Janssen Pharmaceutica Nv | Risperidon ve paliperidon haptenleri. |
| EP3556759B1 (en) | 2012-08-21 | 2023-11-29 | Janssen Pharmaceutica NV | Haptens of paliperidone |
| CA2882557C (en) | 2012-08-21 | 2020-10-27 | Ortho-Clinical Diagnostics, Inc. | Haptens of quetiapine for use in immunoassays |
| ES2978909T3 (es) | 2012-08-21 | 2024-09-23 | Janssen Pharmaceutica Nv | Anticuerpos contra haptenos de aripiprazol y uso de los mismos |
| CN104755928B (zh) | 2012-08-21 | 2017-05-10 | 詹森药业有限公司 | 奥氮平的抗体及其用途 |
| ES2822914T3 (es) | 2012-08-21 | 2021-05-05 | Janssen Pharmaceutica Nv | Haptenos de aripiprazol y su uso en inmunoensayos |
| AU2016370853A1 (en) | 2015-12-17 | 2018-06-07 | Saladax Biomedical Inc. | Antibodies to quetiapine and use thereof |
| CN108431040B (zh) | 2015-12-17 | 2022-07-26 | 詹森药业有限公司 | 利培酮的抗体及其用途 |
| CN114044766B (zh) * | 2021-10-09 | 2022-12-27 | 张北北九食品检验技术有限公司 | 放射性同位素碳-14标记的呋虫胺和中间体及其制备方法和应用 |
| CN120441542B (zh) * | 2025-05-08 | 2025-09-30 | 安徽益普克医药科技发展有限公司 | 一种西洛他唑衍生物及其制备方法与用途 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5535019A (en) | 1978-09-01 | 1980-03-11 | Otsuka Pharmaceut Co Ltd | Carbostyryl derivative |
| ATE134624T1 (de) | 1990-02-19 | 1996-03-15 | Ciba Geigy Ag | Acylverbindungen |
| US6148496A (en) | 1999-04-09 | 2000-11-21 | The Procter & Gamble Company | Method for making a seamless apertured metal belt |
| IT1311924B1 (it) * | 1999-04-13 | 2002-03-20 | Nicox Sa | Composti farmaceutici. |
| DK1653950T3 (da) | 2003-07-31 | 2008-05-26 | Nicox Sa | Nitrooxyderivater af Losartan, Valsatan, Candesartan, Telmisartan, Eprosartan og Olmesartan som angiotensin II-receptorblokkere til behandling af cardiovaskulære sygdomme |
| WO2006079610A1 (en) * | 2005-01-31 | 2006-08-03 | Nicox S.A. | Nitrooxy sartan derivatives as angiotensin ii receptor blockers for the treatment of cardiovascular and inflammatory diseases |
| WO2007019448A2 (en) * | 2005-08-08 | 2007-02-15 | Nitromed, Inc. | Nitric oxide enhancing angiotensin ii antagonist compounds, compositions and methods of use |
-
2008
- 2008-12-02 EP EP08170435A patent/EP2194048A1/en not_active Withdrawn
-
2009
- 2009-12-01 SG SG2011038213A patent/SG171423A1/en unknown
- 2009-12-01 KR KR1020117015258A patent/KR20110088598A/ko not_active Withdrawn
- 2009-12-01 EP EP09793498A patent/EP2367803A1/en not_active Withdrawn
- 2009-12-01 MX MX2011005744A patent/MX2011005744A/es not_active Application Discontinuation
- 2009-12-01 AU AU2009324123A patent/AU2009324123A1/en not_active Abandoned
- 2009-12-01 CN CN200980149072XA patent/CN102245583A/zh active Pending
- 2009-12-01 WO PCT/EP2009/066159 patent/WO2010063724A1/en not_active Ceased
- 2009-12-01 CA CA2745252A patent/CA2745252A1/en not_active Abandoned
- 2009-12-01 US US13/131,722 patent/US8426597B2/en not_active Expired - Fee Related
- 2009-12-01 RU RU2011126607/04A patent/RU2011126607A/ru unknown
- 2009-12-01 BR BRPI0923300A patent/BRPI0923300A2/pt not_active Application Discontinuation
- 2009-12-01 JP JP2011538999A patent/JP2012510502A/ja not_active Ceased
-
2011
- 2011-05-30 IL IL213214A patent/IL213214A0/en unknown
- 2011-05-31 ZA ZA2011/04011A patent/ZA201104011B/en unknown
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