JP2015512645A5 - - Google Patents
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- Publication number
- JP2015512645A5 JP2015512645A5 JP2015504688A JP2015504688A JP2015512645A5 JP 2015512645 A5 JP2015512645 A5 JP 2015512645A5 JP 2015504688 A JP2015504688 A JP 2015504688A JP 2015504688 A JP2015504688 A JP 2015504688A JP 2015512645 A5 JP2015512645 A5 JP 2015512645A5
- Authority
- JP
- Japan
- Prior art keywords
- mutant
- polypeptide
- car
- fatty alcohol
- host cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261619309P | 2012-04-02 | 2012-04-02 | |
| US61/619,309 | 2012-04-02 | ||
| PCT/US2013/035040 WO2013152052A2 (en) | 2012-04-02 | 2013-04-02 | Novel car enzymes and improved production of fatty alcohols |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015512645A JP2015512645A (ja) | 2015-04-30 |
| JP2015512645A5 true JP2015512645A5 (https=) | 2016-09-29 |
| JP6230594B2 JP6230594B2 (ja) | 2017-11-15 |
Family
ID=49237582
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015504688A Active JP6230594B2 (ja) | 2012-04-02 | 2013-04-02 | Ｃａｒ酵素、および改良された脂肪アルコール産生方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (4) | US9340801B2 (https=) |
| EP (6) | EP3153579B1 (https=) |
| JP (1) | JP6230594B2 (https=) |
| KR (6) | KR20210095226A (https=) |
| CN (1) | CN104704113B (https=) |
| AU (2) | AU2013243602B2 (https=) |
| BR (2) | BR122019026987B1 (https=) |
| CA (1) | CA2883064A1 (https=) |
| CO (1) | CO7170148A2 (https=) |
| ES (3) | ES2613553T3 (https=) |
| MX (2) | MX358177B (https=) |
| MY (1) | MY170889A (https=) |
| SI (1) | SI3385374T1 (https=) |
| WO (1) | WO2013152052A2 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101636403B1 (ko) * | 2008-10-28 | 2016-07-05 | 알이지 라이프 사이언시스, 엘엘씨 | 지방족 알코올들을 생산하기 위한 방법들과 조성물들 |
| EP2834352B1 (en) * | 2012-04-02 | 2020-01-08 | Genomatica, Inc. | Improved production of fatty acid derivatives |
| BR122019026987B1 (pt) * | 2012-04-02 | 2022-01-18 | Genomatica, Inc | Polipeptídeo variante da ácido carboxílico redutase (car), célula hospedeira recombinante, cultura de células e método de produzir uma composição de álcool graxo com alto título, rendimento ou produtividade |
| MX2015001780A (es) | 2012-08-10 | 2015-09-28 | Opx Biotechnologies Inc | Microorganismos y métodos para la producción de ácidos grasos y productos derivados de ácidos grasos. |
| US20150119601A1 (en) | 2013-03-15 | 2015-04-30 | Opx Biotechnologies, Inc. | Monofunctional mcr + 3-hp dehydrogenase |
| WO2014145344A2 (en) * | 2013-03-15 | 2014-09-18 | Opx Biotechnologies, Inc. | Control of growth-induction-production phases |
| US11408013B2 (en) | 2013-07-19 | 2022-08-09 | Cargill, Incorporated | Microorganisms and methods for the production of fatty acids and fatty acid derived products |
| EP3022310B1 (en) | 2013-07-19 | 2019-10-16 | Cargill, Incorporated | Microorganisms and methods for the production of fatty acids and fatty acid derived products |
| EP4089176A1 (en) * | 2014-07-18 | 2022-11-16 | Genomatica, Inc. | Microbial production of 1,3 diols |
| EP2993228B1 (en) | 2014-09-02 | 2019-10-09 | Cargill, Incorporated | Production of fatty acid esters |
| CN105985987B (zh) * | 2015-03-02 | 2020-01-31 | 苏州安捷生物科技有限公司 | 一种生物法制备脂肪醇的方法 |
| US10538746B2 (en) | 2016-03-17 | 2020-01-21 | INVISTA North America S.à r.l. | Polypeptides and variants having improved activity, materials and processes relating thereto |
| US11345938B2 (en) | 2017-02-02 | 2022-05-31 | Cargill, Incorporated | Genetically modified cells that produce C6-C10 fatty acid derivatives |
| MY205555A (en) | 2017-04-03 | 2024-10-25 | Genomatica Inc | Thioesterase variants having improved activity for the production of medium-chain fatty acid derivatives |
| EP3844179A4 (en) | 2018-08-31 | 2022-08-31 | Genomatica, Inc. | XYLR MUTANT FOR IMPROVED XYLOSE UTILIZATION OR IMPROVED CO-UTILIZATION OF GLUCOSE AND XYLOSE |
| US12221644B2 (en) | 2018-08-31 | 2025-02-11 | Genomatica, Inc. | Production of non-native monounsaturated fatty acids in bacteria |
| JPWO2022209763A1 (https=) | 2021-03-30 | 2022-10-06 | ||
| EP4493683A1 (en) | 2022-03-16 | 2025-01-22 | Genomatica, Inc. | Acyl-acp thioesterase variants and uses thereof |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5028539A (en) | 1988-08-31 | 1991-07-02 | The University Of Florida | Ethanol production using engineered mutant E. coli |
| US5000000A (en) | 1988-08-31 | 1991-03-19 | University Of Florida | Ethanol production by Escherichia coli strains co-expressing Zymomonas PDC and ADH genes |
| US5482846A (en) | 1988-08-31 | 1996-01-09 | University Of Florida | Ethanol production in Gram-positive microbes |
| US5424202A (en) | 1988-08-31 | 1995-06-13 | The University Of Florida | Ethanol production by recombinant hosts |
| WO1991016427A1 (en) | 1990-04-24 | 1991-10-31 | Stratagene | Methods for phenotype creation from multiple gene populations |
| US5602030A (en) | 1994-03-28 | 1997-02-11 | University Of Florida Research Foundation | Recombinant glucose uptake system |
| US6428767B1 (en) | 1995-05-12 | 2002-08-06 | E. I. Du Pont De Nemours And Company | Method for identifying the source of carbon in 1,3-propanediol |
| US5939250A (en) | 1995-12-07 | 1999-08-17 | Diversa Corporation | Production of enzymes having desired activities by mutagenesis |
| US5965408A (en) | 1996-07-09 | 1999-10-12 | Diversa Corporation | Method of DNA reassembly by interrupting synthesis |
| US7056714B2 (en) * | 2003-03-11 | 2006-06-06 | University Of Iowa Research Foundation, Inc. | Carboxylic acid reductase polypeptide, nucleotide sequence encoding same and methods of use |
| DE102004052115A1 (de) | 2004-10-26 | 2006-04-27 | Westfälische Wilhelms-Universität Münster | Mikroorganismen zur Herstellung von Fettsäureestern, Verfahren zu deren Herstellung und deren Verwendung |
| CA2650773C (en) | 2006-05-19 | 2014-12-02 | Jay D. Keasling | Microorganisms transformed with acetyl-coa carboxylase and wax synthase for production of fatty acid derivatives |
| CN101680009B (zh) | 2007-03-28 | 2017-02-22 | Reg生命科学有限责任公司 | 提高脂肪酸衍生物的产量 |
| BRPI0813359A2 (pt) | 2007-05-22 | 2014-10-14 | Ls9 Inc | Ácidos nucleicos isolados, vetor, células, métodos para produzir um hidrocarboneto, para produzir uma cetona alifática, para produzir um polipeptídeo purificado, para produzir um hidrocarboneto, para produzir biocombustíveis, hidrocarboneto, biocombustível, polipeptídeo isolado, ácido nucleico isolado, organismos geneticamente engenheirados, método para identificar uma enzima útil para a produção de hidrocarbonetos |
| TWI351779B (en) | 2007-12-03 | 2011-11-01 | Advance Smart Ind Ltd | Apparatus and method for correcting residual capac |
| WO2009085278A1 (en) | 2007-12-21 | 2009-07-09 | Ls9, Inc. | Methods and compositions for producing olefins |
| KR101717569B1 (ko) | 2008-10-07 | 2017-03-17 | 알이지 라이프 사이언시스, 엘엘씨 | 지방족 알데히드를 생산하기 위한 방법과 조성물들 |
| KR101636403B1 (ko) * | 2008-10-28 | 2016-07-05 | 알이지 라이프 사이언시스, 엘엘씨 | 지방족 알코올들을 생산하기 위한 방법들과 조성물들 |
| CA3055144C (en) | 2008-12-23 | 2022-07-19 | REG Life Sciences, LLC | Methods and compositions related to thioesterase enzymes |
| US20120115195A1 (en) | 2009-05-01 | 2012-05-10 | The Regents Of The University Of California | Product of fatty acid esters from biomass polymers |
| BRPI1010920B1 (pt) * | 2009-05-22 | 2020-04-28 | Codexis Inc | processo para a produção biológica de álcoois graxos |
| KR20120083908A (ko) * | 2009-10-13 | 2012-07-26 | 게노마티카 인코포레이티드 | 1,4-부탄다이올, 4-하이드록시부탄알, 4-하이드록시부티릴-ｃｏａ, 푸트레신 및 관련 화합물의 제조를 위한 미생물 및 관련 방법 |
| WO2011100667A1 (en) | 2010-02-14 | 2011-08-18 | Ls9, Inc. | Surfactant and cleaning compositions comprising microbially produced branched fatty alcohols |
| US20110250663A1 (en) | 2010-04-08 | 2011-10-13 | Ls9, Inc. | Methods and compositions related to fatty alcohol biosynthetic enzymes |
| BR112013025226A2 (pt) * | 2011-04-01 | 2018-09-11 | Genomatica Inc | micro-organismos para produzir ácido metacrílico e ésteres de metacrilato e métodos relacionados a eles |
| WO2012154329A1 (en) * | 2011-04-01 | 2012-11-15 | Ls9, Inc. | Methods and compositions for improved production of fatty acids and derivatives thereof |
| US8617862B2 (en) * | 2011-06-22 | 2013-12-31 | Genomatica, Inc. | Microorganisms for producing propylene and methods related thereto |
| BR122019026987B1 (pt) * | 2012-04-02 | 2022-01-18 | Genomatica, Inc | Polipeptídeo variante da ácido carboxílico redutase (car), célula hospedeira recombinante, cultura de células e método de produzir uma composição de álcool graxo com alto título, rendimento ou produtividade |
-
2013
- 2013-04-02 BR BR122019026987-4A patent/BR122019026987B1/pt active IP Right Grant
- 2013-04-02 KR KR1020217023277A patent/KR20210095226A/ko not_active Ceased
- 2013-04-02 WO PCT/US2013/035040 patent/WO2013152052A2/en not_active Ceased
- 2013-04-02 ES ES13766728.3T patent/ES2613553T3/es active Active
- 2013-04-02 CN CN201380026546.8A patent/CN104704113B/zh not_active Expired - Fee Related
- 2013-04-02 KR KR1020147030704A patent/KR101831331B1/ko active Active
- 2013-04-02 EP EP16198810.0A patent/EP3153579B1/en not_active Not-in-force
- 2013-04-02 BR BR112014024674-2A patent/BR112014024674B1/pt not_active IP Right Cessation
- 2013-04-02 EP EP18160746.6A patent/EP3385374B1/en active Active
- 2013-04-02 EP EP22202380.6A patent/EP4186974A1/en active Pending
- 2013-04-02 SI SI201331706T patent/SI3385374T1/sl unknown
- 2013-04-02 KR KR1020177026945A patent/KR20170113710A/ko not_active Ceased
- 2013-04-02 KR KR1020207009760A patent/KR102282677B1/ko not_active Expired - Fee Related
- 2013-04-02 KR KR1020197017717A patent/KR102185762B1/ko not_active Expired - Fee Related
- 2013-04-02 JP JP2015504688A patent/JP6230594B2/ja active Active
- 2013-04-02 CA CA2883064A patent/CA2883064A1/en active Pending
- 2013-04-02 KR KR1020197005741A patent/KR102114841B1/ko not_active Expired - Fee Related
- 2013-04-02 MY MYPI2014002838A patent/MY170889A/en unknown
- 2013-04-02 EP EP21191034.4A patent/EP3985108A1/en not_active Withdrawn
- 2013-04-02 ES ES18160746T patent/ES2786633T3/es active Active
- 2013-04-02 US US14/390,350 patent/US9340801B2/en active Active
- 2013-04-02 EP EP13766728.3A patent/EP2834350B1/en active Active
- 2013-04-02 AU AU2013243602A patent/AU2013243602B2/en not_active Ceased
- 2013-04-02 MX MX2016013852A patent/MX358177B/es unknown
- 2013-04-02 ES ES16198810.0T patent/ES2666157T3/es active Active
- 2013-04-02 EP EP19212944.3A patent/EP3674399B1/en active Active
- 2013-04-02 MX MX2014011903A patent/MX343296B/es active IP Right Grant
-
2014
- 2014-10-29 CO CO14240039A patent/CO7170148A2/es unknown
-
2016
- 2016-05-13 US US15/154,636 patent/US9758769B2/en active Active
- 2016-09-20 AU AU2016231497A patent/AU2016231497B2/en not_active Ceased
-
2017
- 2017-09-05 US US15/695,205 patent/US10301603B2/en active Active
-
2019
- 2019-05-16 US US16/414,550 patent/US11034937B2/en active Active
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