JP2015512645A5 - - Google Patents
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- Publication number
- JP2015512645A5 JP2015512645A5 JP2015504688A JP2015504688A JP2015512645A5 JP 2015512645 A5 JP2015512645 A5 JP 2015512645A5 JP 2015504688 A JP2015504688 A JP 2015504688A JP 2015504688 A JP2015504688 A JP 2015504688A JP 2015512645 A5 JP2015512645 A5 JP 2015512645A5
- Authority
- JP
- Japan
- Prior art keywords
- mutant
- polypeptide
- car
- fatty alcohol
- host cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261619309P | 2012-04-02 | 2012-04-02 | |
| US61/619,309 | 2012-04-02 | ||
| PCT/US2013/035040 WO2013152052A2 (en) | 2012-04-02 | 2013-04-02 | Novel car enzymes and improved production of fatty alcohols |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015512645A JP2015512645A (ja) | 2015-04-30 |
| JP2015512645A5 true JP2015512645A5 (https=) | 2016-09-29 |
| JP6230594B2 JP6230594B2 (ja) | 2017-11-15 |
Family
ID=49237582
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015504688A Active JP6230594B2 (ja) | 2012-04-02 | 2013-04-02 | Ｃａｒ酵素、および改良された脂肪アルコール産生方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (4) | US9340801B2 (https=) |
| EP (6) | EP4186974A1 (https=) |
| JP (1) | JP6230594B2 (https=) |
| KR (6) | KR101831331B1 (https=) |
| CN (1) | CN104704113B (https=) |
| AU (2) | AU2013243602B2 (https=) |
| BR (2) | BR112014024674B1 (https=) |
| CA (1) | CA2883064A1 (https=) |
| CO (1) | CO7170148A2 (https=) |
| ES (3) | ES2666157T3 (https=) |
| MX (2) | MX343296B (https=) |
| MY (1) | MY170889A (https=) |
| SI (1) | SI3385374T1 (https=) |
| WO (1) | WO2013152052A2 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101700296B1 (ko) * | 2008-10-28 | 2017-01-26 | 알이지 라이프 사이언시스, 엘엘씨 | 지방족 알코올들을 생산하기 위한 방법들과 조성물들 |
| CN104704113B (zh) * | 2012-04-02 | 2018-01-23 | Reg生命科学有限责任公司 | Car酶及脂肪醇的改良生产 |
| MX379251B (es) * | 2012-04-02 | 2025-03-11 | Genomatica Inc | Producción mejorada de derivados de ácidos grasos. |
| SG11201501013PA (en) | 2012-08-10 | 2015-04-29 | Opx Biotechnologies Inc | Microorganisms and methods for the production of fatty acids and fatty acid derived products |
| WO2014145332A1 (en) * | 2013-03-15 | 2014-09-18 | Opx Biotechnologies, Inc. | Monfunctional mcr + 3-hp dehydrogenase |
| WO2014146026A1 (en) | 2013-03-15 | 2014-09-18 | Opx Biotechnologies, Inc. | Bioproduction of chemicals |
| US11408013B2 (en) | 2013-07-19 | 2022-08-09 | Cargill, Incorporated | Microorganisms and methods for the production of fatty acids and fatty acid derived products |
| CN106795483A (zh) | 2013-07-19 | 2017-05-31 | 嘉吉公司 | 用于生产脂肪酸和脂肪酸衍生产物的微生物及方法 |
| KR20170029625A (ko) * | 2014-07-18 | 2017-03-15 | 알이지 라이프 사이언시스, 엘엘씨 | 지방 디올의 미생물 생산 |
| EP2993228B1 (en) | 2014-09-02 | 2019-10-09 | Cargill, Incorporated | Production of fatty acid esters |
| CN105985987B (zh) * | 2015-03-02 | 2020-01-31 | 苏州安捷生物科技有限公司 | 一种生物法制备脂肪醇的方法 |
| EP3430133A1 (en) | 2016-03-17 | 2019-01-23 | INVISTA Textiles (U.K.) Limited | Carboxylic acid reductase polypeptides and variants having improved activity, materials and processes relating thereto |
| EP3577227A4 (en) | 2017-02-02 | 2020-12-30 | Cargill Inc. | GENETICALLY MODIFIED CELLS PRODUCING C6-C10 FATTY ACID DERIVATIVES |
| CN111094558A (zh) | 2017-04-03 | 2020-05-01 | 基因组股份公司 | 对产生中链脂肪酸衍生物具有改善的活性的硫酯酶变体 |
| US12098168B2 (en) | 2018-08-31 | 2024-09-24 | Genomatica, Inc. | XylR mutant for improved xylose utilization or improved co-utilization of glucose and xylose preliminary |
| WO2020047088A1 (en) | 2018-08-31 | 2020-03-05 | Genomatica, Inc. | Production of non-native monounsaturated fatty acids in bacteria |
| KR20230160398A (ko) | 2021-03-30 | 2023-11-23 | 아사히 가세이 가부시키가이샤 | 카르복실산 환원 활성을 갖는 재조합 폴리펩티드 |
| WO2023178193A1 (en) | 2022-03-16 | 2023-09-21 | Genomatica, Inc. | Acyl-acp thioesterase variants and uses thereof |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5424202A (en) | 1988-08-31 | 1995-06-13 | The University Of Florida | Ethanol production by recombinant hosts |
| US5482846A (en) | 1988-08-31 | 1996-01-09 | University Of Florida | Ethanol production in Gram-positive microbes |
| US5028539A (en) | 1988-08-31 | 1991-07-02 | The University Of Florida | Ethanol production using engineered mutant E. coli |
| US5000000A (en) | 1988-08-31 | 1991-03-19 | University Of Florida | Ethanol production by Escherichia coli strains co-expressing Zymomonas PDC and ADH genes |
| WO1991016427A1 (en) | 1990-04-24 | 1991-10-31 | Stratagene | Methods for phenotype creation from multiple gene populations |
| US5602030A (en) | 1994-03-28 | 1997-02-11 | University Of Florida Research Foundation | Recombinant glucose uptake system |
| US6428767B1 (en) | 1995-05-12 | 2002-08-06 | E. I. Du Pont De Nemours And Company | Method for identifying the source of carbon in 1,3-propanediol |
| US5965408A (en) | 1996-07-09 | 1999-10-12 | Diversa Corporation | Method of DNA reassembly by interrupting synthesis |
| US5939250A (en) | 1995-12-07 | 1999-08-17 | Diversa Corporation | Production of enzymes having desired activities by mutagenesis |
| US7056714B2 (en) * | 2003-03-11 | 2006-06-06 | University Of Iowa Research Foundation, Inc. | Carboxylic acid reductase polypeptide, nucleotide sequence encoding same and methods of use |
| DE102004052115A1 (de) | 2004-10-26 | 2006-04-27 | Westfälische Wilhelms-Universität Münster | Mikroorganismen zur Herstellung von Fettsäureestern, Verfahren zu deren Herstellung und deren Verwendung |
| EP2024491B1 (en) | 2006-05-19 | 2014-11-19 | LS9, Inc. | Production of fatty acids and derivatives thereof |
| CA3178593A1 (en) | 2007-03-28 | 2008-10-02 | Genomatica, Inc. | Enhanced production of fatty acid derivatives |
| JP5912251B2 (ja) | 2007-05-22 | 2016-06-01 | アールイージー ライフ サイエンシズ リミテッド ライアビリティ カンパニー | 炭化水素産生遺伝子およびその使用方法 |
| TWI351779B (en) | 2007-12-03 | 2011-11-01 | Advance Smart Ind Ltd | Apparatus and method for correcting residual capac |
| US8183028B2 (en) | 2007-12-21 | 2012-05-22 | Ls9, Inc. | Methods and compositions for producing olefins |
| JP2012504963A (ja) | 2008-10-07 | 2012-03-01 | エルエス９・インコーポレイテッド | 脂肪アルデヒドを生産するための方法および組成物 |
| KR101700296B1 (ko) | 2008-10-28 | 2017-01-26 | 알이지 라이프 사이언시스, 엘엘씨 | 지방족 알코올들을 생산하기 위한 방법들과 조성물들 |
| EP3564345A1 (en) * | 2008-12-23 | 2019-11-06 | REG Life Sciences, LLC | Methods and compositions related to thioesterase enzymes |
| BRPI1009980A2 (pt) | 2009-05-01 | 2015-08-25 | Univ California | Produtos de ésteres de ácidos graxos a partir de polímeros de biomassa |
| EP2432890B1 (en) * | 2009-05-22 | 2015-09-02 | Codexis, Inc. | Engineered biosynthesis of fatty alcohols |
| US8377666B2 (en) * | 2009-10-13 | 2013-02-19 | Genomatica, Inc. | Microorganisms for the production of 1,4-butanediol, 4-hydroxybutanal, 4-hydroxybutyryl-coa, putrescine and related compounds, and methods related thereto |
| WO2011100667A1 (en) | 2010-02-14 | 2011-08-18 | Ls9, Inc. | Surfactant and cleaning compositions comprising microbially produced branched fatty alcohols |
| US20110250663A1 (en) | 2010-04-08 | 2011-10-13 | Ls9, Inc. | Methods and compositions related to fatty alcohol biosynthetic enzymes |
| EP3702363A1 (en) * | 2011-04-01 | 2020-09-02 | Genomatica, Inc. | Fadr overexpressing bacterial cells for improved production of fatty acids and derivatives thereof |
| JP2014518613A (ja) * | 2011-04-01 | 2014-08-07 | ジェノマティカ・インコーポレイテッド | メタクリル酸およびメタクリレートエステルの産生のための微生物ならびにそれに関連する方法 |
| US8617862B2 (en) * | 2011-06-22 | 2013-12-31 | Genomatica, Inc. | Microorganisms for producing propylene and methods related thereto |
| CN104704113B (zh) * | 2012-04-02 | 2018-01-23 | Reg生命科学有限责任公司 | Car酶及脂肪醇的改良生产 |
-
2013
- 2013-04-02 CN CN201380026546.8A patent/CN104704113B/zh not_active Expired - Fee Related
- 2013-04-02 JP JP2015504688A patent/JP6230594B2/ja active Active
- 2013-04-02 SI SI201331706T patent/SI3385374T1/sl unknown
- 2013-04-02 MY MYPI2014002838A patent/MY170889A/en unknown
- 2013-04-02 EP EP22202380.6A patent/EP4186974A1/en active Pending
- 2013-04-02 KR KR1020147030704A patent/KR101831331B1/ko active Active
- 2013-04-02 CA CA2883064A patent/CA2883064A1/en active Pending
- 2013-04-02 AU AU2013243602A patent/AU2013243602B2/en not_active Ceased
- 2013-04-02 EP EP21191034.4A patent/EP3985108A1/en not_active Withdrawn
- 2013-04-02 WO PCT/US2013/035040 patent/WO2013152052A2/en not_active Ceased
- 2013-04-02 EP EP16198810.0A patent/EP3153579B1/en not_active Not-in-force
- 2013-04-02 MX MX2014011903A patent/MX343296B/es active IP Right Grant
- 2013-04-02 US US14/390,350 patent/US9340801B2/en active Active
- 2013-04-02 KR KR1020207009760A patent/KR102282677B1/ko not_active Expired - Fee Related
- 2013-04-02 EP EP19212944.3A patent/EP3674399B1/en active Active
- 2013-04-02 KR KR1020217023277A patent/KR20210095226A/ko not_active Ceased
- 2013-04-02 ES ES16198810.0T patent/ES2666157T3/es active Active
- 2013-04-02 ES ES18160746T patent/ES2786633T3/es active Active
- 2013-04-02 ES ES13766728.3T patent/ES2613553T3/es active Active
- 2013-04-02 KR KR1020197017717A patent/KR102185762B1/ko not_active Expired - Fee Related
- 2013-04-02 BR BR112014024674-2A patent/BR112014024674B1/pt not_active IP Right Cessation
- 2013-04-02 KR KR1020177026945A patent/KR20170113710A/ko not_active Ceased
- 2013-04-02 MX MX2016013852A patent/MX358177B/es unknown
- 2013-04-02 EP EP18160746.6A patent/EP3385374B1/en active Active
- 2013-04-02 KR KR1020197005741A patent/KR102114841B1/ko not_active Expired - Fee Related
- 2013-04-02 EP EP13766728.3A patent/EP2834350B1/en active Active
- 2013-04-02 BR BR122019026987-4A patent/BR122019026987B1/pt active IP Right Grant
-
2014
- 2014-10-29 CO CO14240039A patent/CO7170148A2/es unknown
-
2016
- 2016-05-13 US US15/154,636 patent/US9758769B2/en active Active
- 2016-09-20 AU AU2016231497A patent/AU2016231497B2/en not_active Ceased
-
2017
- 2017-09-05 US US15/695,205 patent/US10301603B2/en active Active
-
2019
- 2019-05-16 US US16/414,550 patent/US11034937B2/en active Active
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