KR20210095226A - Ｃａｒ 효소들 및 지방족 알코올들의 개선된 생산 - Google Patents

Ｃａｒ 효소들 및 지방족 알코올들의 개선된 생산 Download PDF

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KR20210095226A
KR20210095226A KR1020217023277A KR20217023277A KR20210095226A KR 20210095226 A KR20210095226 A KR 20210095226A KR 1020217023277 A KR1020217023277 A KR 1020217023277A KR 20217023277 A KR20217023277 A KR 20217023277A KR 20210095226 A KR20210095226 A KR 20210095226A
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val
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데렉 엘. 그린필드
엘리자베스 제이. 클라크
엘리 에스. 그로반
비크란트 알라가다
성원 이
쉐지 리
지하오 흐
바오롱 주
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게노마티카 인코포레이티드
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C12Y102/0105—Long-chain-fatty-acyl-CoA reductase (1.2.1.50)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/99—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with other acceptors (1.2.99)
    • C12Y102/99006—Carboxylate reductase (1.2.99.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01041—Beta-ketoacyl-acyl-carrier-protein synthase I (2.3.1.41)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/02—Thioester hydrolases (3.1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P2203/00—Fermentation products obtained from optionally pretreated or hydrolyzed cellulosic or lignocellulosic material as the carbon source
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
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  • Engineering & Computer Science (AREA)
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  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
KR1020217023277A 2012-04-02 2013-04-02 Ｃａｒ 효소들 및 지방족 알코올들의 개선된 생산 Ceased KR20210095226A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261619309P 2012-04-02 2012-04-02
US61/619,309 2012-04-02
KR1020207009760A KR102282677B1 (ko) 2012-04-02 2013-04-02 Ｃａｒ 효소들 및 지방족 알코올들의 개선된 생산
PCT/US2013/035040 WO2013152052A2 (en) 2012-04-02 2013-04-02 Novel car enzymes and improved production of fatty alcohols

Related Parent Applications (1)

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KR1020207009760A Division KR102282677B1 (ko) 2012-04-02 2013-04-02 Ｃａｒ 효소들 및 지방족 알코올들의 개선된 생산

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KR20210095226A true KR20210095226A (ko) 2021-07-30

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KR1020217023277A Ceased KR20210095226A (ko) 2012-04-02 2013-04-02 Ｃａｒ 효소들 및 지방족 알코올들의 개선된 생산
KR1020147030704A Active KR101831331B1 (ko) 2012-04-02 2013-04-02 Ｃａｒ 효소들 및 지방족 알코올들의 개선된 생산
KR1020177026945A Ceased KR20170113710A (ko) 2012-04-02 2013-04-02 Ｃａｒ 효소들 및 지방족 알코올들의 개선된 생산
KR1020207009760A Expired - Fee Related KR102282677B1 (ko) 2012-04-02 2013-04-02 Ｃａｒ 효소들 및 지방족 알코올들의 개선된 생산
KR1020197017717A Expired - Fee Related KR102185762B1 (ko) 2012-04-02 2013-04-02 Ｃａｒ 효소들 및 지방족 알코올들의 개선된 생산
KR1020197005741A Expired - Fee Related KR102114841B1 (ko) 2012-04-02 2013-04-02 Ｃａｒ 효소들 및 지방족 알코올들의 개선된 생산

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KR1020147030704A Active KR101831331B1 (ko) 2012-04-02 2013-04-02 Ｃａｒ 효소들 및 지방족 알코올들의 개선된 생산
KR1020177026945A Ceased KR20170113710A (ko) 2012-04-02 2013-04-02 Ｃａｒ 효소들 및 지방족 알코올들의 개선된 생산
KR1020207009760A Expired - Fee Related KR102282677B1 (ko) 2012-04-02 2013-04-02 Ｃａｒ 효소들 및 지방족 알코올들의 개선된 생산
KR1020197017717A Expired - Fee Related KR102185762B1 (ko) 2012-04-02 2013-04-02 Ｃａｒ 효소들 및 지방족 알코올들의 개선된 생산
KR1020197005741A Expired - Fee Related KR102114841B1 (ko) 2012-04-02 2013-04-02 Ｃａｒ 효소들 및 지방족 알코올들의 개선된 생산

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US (4) US9340801B2 (https=)
EP (6) EP3153579B1 (https=)
JP (1) JP6230594B2 (https=)
KR (6) KR20210095226A (https=)
CN (1) CN104704113B (https=)
AU (2) AU2013243602B2 (https=)
BR (2) BR122019026987B1 (https=)
CA (1) CA2883064A1 (https=)
CO (1) CO7170148A2 (https=)
ES (3) ES2613553T3 (https=)
MX (2) MX358177B (https=)
MY (1) MY170889A (https=)
SI (1) SI3385374T1 (https=)
WO (1) WO2013152052A2 (https=)

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US10301603B2 (en) 2019-05-28
MY170889A (en) 2019-09-12
KR20170113710A (ko) 2017-10-12
US11034937B2 (en) 2021-06-15
MX2014011903A (es) 2015-05-12
EP3153579B1 (en) 2018-03-14
KR20150032660A (ko) 2015-03-27
ES2613553T3 (es) 2017-05-24
EP2834350B1 (en) 2016-11-16
MX358177B (es) 2018-08-08
EP3385374A1 (en) 2018-10-10
KR102185762B1 (ko) 2020-12-02
US9340801B2 (en) 2016-05-17
US20180135028A1 (en) 2018-05-17
US20200109374A1 (en) 2020-04-09
WO2013152052A2 (en) 2013-10-10
CO7170148A2 (es) 2015-01-28
CN104704113B (zh) 2018-01-23
KR20200038559A (ko) 2020-04-13
AU2013243602B2 (en) 2016-11-24
US20160326499A1 (en) 2016-11-10
ES2786633T3 (es) 2020-10-13
CA2883064A1 (en) 2013-10-10
EP3385374B1 (en) 2020-01-08
SI3385374T1 (sl) 2020-09-30
AU2016231497A1 (en) 2016-10-06
AU2016231497B2 (en) 2017-08-31
US20150064757A1 (en) 2015-03-05
BR122019026987B1 (pt) 2022-01-18
KR102114841B1 (ko) 2020-05-26
JP6230594B2 (ja) 2017-11-15
EP4186974A1 (en) 2023-05-31
EP3985108A1 (en) 2022-04-20
AU2013243602A1 (en) 2014-11-13
MX343296B (es) 2016-11-01
KR102282677B1 (ko) 2021-07-28
JP2015512645A (ja) 2015-04-30
BR112014024674B1 (pt) 2022-06-07
WO2013152052A3 (en) 2014-03-13
KR20190076059A (ko) 2019-07-01
EP3674399B1 (en) 2021-09-22
ES2666157T3 (es) 2018-05-03
CN104704113A (zh) 2015-06-10
EP3153579A1 (en) 2017-04-12
KR101831331B1 (ko) 2018-02-23
KR20190022935A (ko) 2019-03-06
EP3674399A1 (en) 2020-07-01
US9758769B2 (en) 2017-09-12
BR112014024674A2 (pt) 2018-11-21
EP2834350A2 (en) 2015-02-11

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