BRPI1010920B1 - processo para a produção biológica de álcoois graxos - Google Patents
processo para a produção biológica de álcoois graxos Download PDFInfo
- Publication number
- BRPI1010920B1 BRPI1010920B1 BRPI1010920A BRPI1010920A BRPI1010920B1 BR PI1010920 B1 BRPI1010920 B1 BR PI1010920B1 BR PI1010920 A BRPI1010920 A BR PI1010920A BR PI1010920 A BRPI1010920 A BR PI1010920A BR PI1010920 B1 BRPI1010920 B1 BR PI1010920B1
- Authority
- BR
- Brazil
- Prior art keywords
- fatty alcohols
- production
- organic production
- long chain
- fatty
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1288—Transferases for other substituted phosphate groups (2.7.8)
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
processo para a produção biológica de álcoois graxos a presente invenção trata de processos para a produção de alcoóis graxos de cadeia longa por células hospedeiras recombinantes que expressam um ou mais enzimas ácido carboxílico redutase heteróloga eficientes na conversão de ácidos graxos e seus derivados em alcoóis graxos de cadeia longa.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18053409P | 2009-05-22 | 2009-05-22 | |
PCT/US2010/035737 WO2010135624A2 (en) | 2009-05-22 | 2010-05-21 | Engineered biosynthesis of fatty alcohols |
Publications (2)
Publication Number | Publication Date |
---|---|
BRPI1010920A2 BRPI1010920A2 (pt) | 2017-07-11 |
BRPI1010920B1 true BRPI1010920B1 (pt) | 2020-04-28 |
Family
ID=43124998
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI1010920A BRPI1010920B1 (pt) | 2009-05-22 | 2010-05-21 | processo para a produção biológica de álcoois graxos |
Country Status (4)
Country | Link |
---|---|
US (1) | US20100298612A1 (pt) |
EP (1) | EP2432890B1 (pt) |
BR (1) | BRPI1010920B1 (pt) |
WO (1) | WO2010135624A2 (pt) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
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US20110151526A1 (en) | 2009-12-22 | 2011-06-23 | Charles Winston Saunders | Branched-Chain Fatty Acids And Biological Production Thereof |
US8933131B2 (en) | 2010-01-12 | 2015-01-13 | The Procter & Gamble Company | Intermediates and surfactants useful in household cleaning and personal care compositions, and methods of making the same |
US8372610B2 (en) * | 2010-09-15 | 2013-02-12 | Ls9, Inc. | Production of odd chain fatty acid derivatives in recombinant microbial cells |
US20130035513A1 (en) * | 2011-01-26 | 2013-02-07 | Ls9, Inc. | Methods and compositions for enhanced production of fatty aldehydes and fatty alcohols |
WO2012174451A1 (en) | 2011-06-17 | 2012-12-20 | Invista Technologies S.A.R.L. | Use of hydrolases to increase monomer content in waste stream |
US20130034884A1 (en) | 2011-06-22 | 2013-02-07 | Genomatica, Inc. | Microorganisms for producing 1,4-butanediol and methods related thereto |
EP2726627A2 (en) | 2011-06-30 | 2014-05-07 | Invista Technologies S.à.r.l. | Bioconversion process for producing nylon-7, nylon-7,7 and polyesters |
DE102011110945A1 (de) | 2011-08-15 | 2013-02-21 | Evonik Degussa Gmbh | Biotechnologisches Syntheseverfahren von organischen Verbindungen mit alkIL-Genprodukt |
DE102011110946A1 (de) | 2011-08-15 | 2016-01-21 | Evonik Degussa Gmbh | Biotechnologisches Syntheseverfahren von omegafunktionalisierten Carbonsäuren und Carbonsäure-Estern aus einfachen Kohlenstoffquellen |
EP2753701B1 (en) | 2011-09-27 | 2018-05-02 | ExxonMobil Research and Engineering Company | Acyl-acp wax ester synthases |
US9102958B2 (en) | 2011-12-16 | 2015-08-11 | Invista North America S.á.r.l. | Methods of producing 6-carbon chemicals via CoA-dependent carbon chain elongation associated with carbon storage |
US9102960B2 (en) | 2011-12-16 | 2015-08-11 | Invista North America S.á.r.l. | Methods of producing 6-carbon chemicals via CoA-dependent carbon chain elongation associated with carbon storage |
EP2814972B1 (en) | 2012-02-24 | 2020-04-22 | ExxonMobil Research and Engineering Company | Enhanced production of fatty acids and fatty acid derivatives by recombinant microorganisms |
US9096834B2 (en) | 2012-02-24 | 2015-08-04 | Exxonmobil Research And Engineering Company | Recombinant microorganisms comprising thioesterase and lysophosphatidic acid acyltransferase genes for fatty acid production |
US8962299B2 (en) | 2012-02-29 | 2015-02-24 | Exxonmobil Research And Engineering Company | Four-gene pathway for wax ester synthesis |
EP3674399B1 (en) * | 2012-04-02 | 2021-09-22 | Genomatica, Inc. | Car enzymes and improved production of fatty alcohols |
US9181568B2 (en) | 2012-04-23 | 2015-11-10 | Exxonmobil Research And Engineering Company | Cell systems and methods for improving fatty acid synthesis by expression of dehydrogenases |
KR20150069015A (ko) | 2012-10-15 | 2015-06-22 | 게노마티카 인코포레이티드 | 특정 길이의 지방 알콜 및 관련 화합물의 생산을 위한 미생물 및 방법 |
RU2015109898A (ru) | 2012-11-09 | 2017-01-10 | Калиста, Инк. | Композиции и способы биологического получения производных жирных кислот |
BR112015013413A2 (pt) | 2012-12-14 | 2017-11-14 | Invista Tech Sarl | método para biosintetizar um produto e hospedeiro recombinante |
EP2746400A1 (de) * | 2012-12-21 | 2014-06-25 | Evonik Industries AG | Herstellung von Aminen und Diaminen aus einer Carbonsäure oder Dicarbonsäure oder eines Monoesters davon |
EP2746397A1 (de) * | 2012-12-21 | 2014-06-25 | Evonik Industries AG | Herstellung von Omega-Aminofettsäuren |
EP2938733A2 (en) | 2012-12-31 | 2015-11-04 | Invista North America S.a.r.l. | Methods of producing 7-carbon chemicals via methyl-ester shielded carbon chain elongation |
CN105073214A (zh) | 2012-12-31 | 2015-11-18 | 英威达技术有限责任公司 | 通过甲酯保护的碳链延伸生产6碳化学物的方法 |
EP2938736A2 (en) | 2012-12-31 | 2015-11-04 | Invista Technologies S.A R.L. | Methods of producing 7-carbon chemicals via c1 carbon chain elongation associated with coenzyme b synthesis |
EP2938732A1 (en) | 2012-12-31 | 2015-11-04 | Invista Technologies S.à.r.l. | Methods of producing 7-carbon chemicals from long chain fatty acids via oxidative cleavage |
WO2014105788A2 (en) | 2012-12-31 | 2014-07-03 | Invista North America S.A.R.L. | Methods of producing 7-carbon chemicals via carbon chain elongation associated with cyclohexane carboxylate synthesis |
CN105026569A (zh) | 2012-12-31 | 2015-11-04 | 英威达技术有限责任公司 | 通过丙酮酸和琥珀酸半醛羟醛缩合生产7-碳化学物的方法 |
EP2938734A2 (en) | 2012-12-31 | 2015-11-04 | Invista Technologies S.A R.L. | Methods of producing 7-carbon chemicals via aromatic compounds |
KR102082247B1 (ko) * | 2013-01-16 | 2020-02-28 | 알이지 라이프 사이언시스, 엘엘씨 | 개선된 특성들을 갖는 아실-acp 레덕타아제 |
AR095504A1 (es) | 2013-03-15 | 2015-10-21 | Consejo Nac De Investig Científicas Y Técnicas (Conicet) | Organismos obtenidos mediante ingeniería para la producción de lípidos |
US9850512B2 (en) | 2013-03-15 | 2017-12-26 | The Research Foundation For The State University Of New York | Hydrolysis of cellulosic fines in primary clarified sludge of paper mills and the addition of a surfactant to increase the yield |
CN113493759A (zh) | 2013-09-13 | 2021-10-12 | 基因组股份公司 | 改进的乙酰-coa羧化酶变体 |
US20160376600A1 (en) | 2013-11-25 | 2016-12-29 | Genomatica, Inc. | Methods for enhancing microbial production of specific length fatty alcohols in the presence of methanol |
US9951363B2 (en) | 2014-03-14 | 2018-04-24 | The Research Foundation for the State University of New York College of Environmental Science and Forestry | Enzymatic hydrolysis of old corrugated cardboard (OCC) fines from recycled linerboard mill waste rejects |
US20170152531A1 (en) | 2014-06-16 | 2017-06-01 | North America S.A.R.L. | Process for producing glutarate and glutaric acid methyl ester |
BR112016029399A2 (pt) | 2014-06-16 | 2017-10-17 | Invista Tech Sarl | métodos, reagentes e células para biossintetizar composto |
BR112016029375A2 (pt) | 2014-06-16 | 2017-10-17 | Invista Tech Sarl | métodos, reagentes e células para biossintetizar compostos |
EP3155106A2 (en) | 2014-06-16 | 2017-04-19 | Invista Technologies S.à.r.l. | Methods, reagents and cells for biosynthesizing compound |
AU2015289430B2 (en) * | 2014-07-18 | 2020-03-05 | Genomatica, Inc. | Microbial production of fatty diols |
WO2019023524A2 (en) * | 2017-07-27 | 2019-01-31 | University Of Florida Research Foundation, Incorporated | CYANOBACTERIAL HOSTS AND METHODS FOR PRODUCING CHEMICALS |
US20240229086A1 (en) * | 2021-03-29 | 2024-07-11 | Genomatica, Inc. | Production Of Non-Native Monounsaturated Fatty Acids In Bacteria |
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IN163393B (pt) | 1983-10-06 | 1988-09-17 | Pfizer | |
US5071764A (en) | 1983-10-06 | 1991-12-10 | Pfizer Inc. | Process for integrative transformation of yarrowia lipolytica |
US4889741A (en) | 1987-04-13 | 1989-12-26 | Cornell Research Foundation, Inc. | Processed egg product |
CN1192108C (zh) | 1994-06-03 | 2005-03-09 | 诺沃奇梅兹生物技术有限公司 | 纯化的毁丝霉属漆酶及编码该酶的核酸 |
ATE294871T1 (de) | 1994-06-30 | 2005-05-15 | Novozymes Biotech Inc | Nicht-toxisches, nicht-toxigenes, nicht- pathogenes fusarium expressionssystem und darin zu verwendende promotoren und terminatoren |
US6579695B1 (en) | 1995-10-13 | 2003-06-17 | President And Fellows Of Harvard College | Phosphopantetheinyl transferases and uses thereof |
US5795759A (en) * | 1997-03-10 | 1998-08-18 | The University Of Iowa Research Foundation | Carboxylic acid reductase, and methods of using same |
US7074559B2 (en) * | 2002-03-06 | 2006-07-11 | Refents of the University of Minnesota | Mycobacterial diagnostics |
US7056714B2 (en) * | 2003-03-11 | 2006-06-06 | University Of Iowa Research Foundation, Inc. | Carboxylic acid reductase polypeptide, nucleotide sequence encoding same and methods of use |
US7629157B2 (en) | 2003-08-11 | 2009-12-08 | Codexis, Inc. | Ketoreductase polypeptides and related polynucleotides |
WO2007142784A1 (en) * | 2006-05-31 | 2007-12-13 | Archer-Daniels-Midland Company | Enzymatic method of making aldehydes from fatty acids |
US7879585B2 (en) | 2006-10-02 | 2011-02-01 | Codexis, Inc. | Ketoreductase enzymes and uses thereof |
US7820421B2 (en) | 2007-02-08 | 2010-10-26 | Codexis, Inc. | Ketoreductases and uses thereof |
JP2012504963A (ja) * | 2008-10-07 | 2012-03-01 | エルエス9・インコーポレイテッド | 脂肪アルデヒドを生産するための方法および組成物 |
CA3041892C (en) | 2008-10-28 | 2022-03-15 | REG Life Sciences, LLC | Methods for producing a fatty alcohol in a host cell |
-
2010
- 2010-05-21 US US12/784,770 patent/US20100298612A1/en not_active Abandoned
- 2010-05-21 EP EP10778451.4A patent/EP2432890B1/en active Active
- 2010-05-21 WO PCT/US2010/035737 patent/WO2010135624A2/en active Application Filing
- 2010-05-21 BR BRPI1010920A patent/BRPI1010920B1/pt active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
WO2010135624A2 (en) | 2010-11-25 |
EP2432890B1 (en) | 2015-09-02 |
BRPI1010920A2 (pt) | 2017-07-11 |
EP2432890A2 (en) | 2012-03-28 |
US20100298612A1 (en) | 2010-11-25 |
WO2010135624A3 (en) | 2011-01-13 |
EP2432890A4 (en) | 2012-11-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25A | Requested transfer of rights approved |
Owner name: SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (N Owner name: SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) |
|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B06T | Formal requirements before examination [chapter 6.20 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 21/05/2010, OBSERVADAS AS CONDICOES LEGAIS. |