BR112014015202A8 - processo para a melhor separação de uma solução orgânica hidrófoba de um meio de cultura aquoso - Google Patents

processo para a melhor separação de uma solução orgânica hidrófoba de um meio de cultura aquoso

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Publication number
BR112014015202A8
BR112014015202A8 BR112014015202A BR112014015202A BR112014015202A8 BR 112014015202 A8 BR112014015202 A8 BR 112014015202A8 BR 112014015202 A BR112014015202 A BR 112014015202A BR 112014015202 A BR112014015202 A BR 112014015202A BR 112014015202 A8 BR112014015202 A8 BR 112014015202A8
Authority
BR
Brazil
Prior art keywords
culture medium
organic solution
aqueous culture
hydrophobic organic
cell
Prior art date
Application number
BR112014015202A
Other languages
English (en)
Other versions
BR112014015202B1 (pt
BR112014015202A2 (pt
Inventor
Erhardt Frank
Hennemann Hans-Georg
Corthals Jasmin
Berse Katharina
Schiebelhut Marion
Pötter Markus
Wessel Mirja
Hafkemeyer Sabine
Schaffer Steffen
Haas Thomas
Original Assignee
Evonik Industries Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evonik Industries Ag filed Critical Evonik Industries Ag
Publication of BR112014015202A8 publication Critical patent/BR112014015202A8/pt
Publication of BR112014015202A2 publication Critical patent/BR112014015202A2/pt
Publication of BR112014015202B1 publication Critical patent/BR112014015202B1/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y103/00—Oxidoreductases acting on the CH-CH group of donors (1.3)
    • C12Y103/99—Oxidoreductases acting on the CH-CH group of donors (1.3) with other acceptors (1.3.99)
    • C12Y103/99003—Acyl-CoA dehydrogenase (1.3.99.3)

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

resumo patente de invenção: "processo para a melhor separação de uma solução orgânica hidrófoba de um meio de cultura aquoso". a presente invenção refere-se a um processo para a melhor separação de uma solução orgânica hidrófoba de um meio de cultura aquosa, compreendendo as etapas, preparação de um meio de cultura aquoso compreendendo uma célula metabolicamente ativa, o contato do meio de cultura aquoso com uma solução orgânica hidrófoba, separação da solução orgânica hidrófoba do meio de cultura aquoso, em que a célula apresenta uma atividade reduzida de pelo menos uma enzima comparada com o tipo selvagem da célula, que catalisa uma das reações da ß-oxidação de ácidos graxos. além disso, a invenção se refere ao uso de uma célula metabolicamente ativa, que apresenta uma atividade reduzida de uma enzima comparada com o tipo selvagem da célula, que catalisa uma das reações da ß-oxidação de ácidos graxos, preferivelmente de uma enzima selecionada do grupo compreendendo fada, fadb, fadd, fadl e fade, bem como variantes dos mesmos, mais preferivelmente fade ou uma variante do mesmo, para a melhor separação de uma solução orgânica hidrófoba de um meio de cultura aquoso compreendendo a célula metabolicamente ativa.
BR112014015202-0A 2011-12-22 2012-12-18 Processo para a melhor separação de uma solução orgânica hidrófoba de um meio de cultura aquoso BR112014015202B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11195221.4 2011-12-22
EP11195221.4A EP2607490A1 (de) 2011-12-22 2011-12-22 Verfahren zur verbesserten Abtrennung einer hydrophoben organischen Lösung von einem wässrigen Kulturmedium
PCT/EP2012/075889 WO2013092547A1 (de) 2011-12-22 2012-12-18 Verfahren zur verbesserten abtrennung einer hydrophoben organischen lösung von einem wässrigen kulturmedium

Publications (3)

Publication Number Publication Date
BR112014015202A8 true BR112014015202A8 (pt) 2017-06-13
BR112014015202A2 BR112014015202A2 (pt) 2017-06-13
BR112014015202B1 BR112014015202B1 (pt) 2021-11-03

Family

ID=47351527

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014015202-0A BR112014015202B1 (pt) 2011-12-22 2012-12-18 Processo para a melhor separação de uma solução orgânica hidrófoba de um meio de cultura aquoso

Country Status (11)

Country Link
US (1) US9249435B2 (pt)
EP (3) EP2607490A1 (pt)
JP (1) JP6312117B2 (pt)
KR (1) KR102000317B1 (pt)
CN (2) CN103254089A (pt)
BR (1) BR112014015202B1 (pt)
CA (1) CA2799883C (pt)
ES (1) ES2688295T3 (pt)
MX (1) MX339910B (pt)
SG (1) SG11201403495QA (pt)
WO (1) WO2013092547A1 (pt)

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Also Published As

Publication number Publication date
US20130164797A1 (en) 2013-06-27
WO2013092547A1 (de) 2013-06-27
EP2794898B1 (de) 2018-08-01
KR102000317B1 (ko) 2019-07-15
EP2607490A1 (de) 2013-06-26
SG11201403495QA (en) 2014-09-26
CN103254089A (zh) 2013-08-21
JP6312117B2 (ja) 2018-04-18
EP2607491A1 (de) 2013-06-26
BR112014015202B1 (pt) 2021-11-03
JP2013132295A (ja) 2013-07-08
US9249435B2 (en) 2016-02-02
BR112014015202A2 (pt) 2017-06-13
MX2012015064A (es) 2013-10-16
EP2794898A1 (de) 2014-10-29
CN108358800A (zh) 2018-08-03
ES2688295T3 (es) 2018-10-31
KR20140111653A (ko) 2014-09-19
CN108358800B (zh) 2023-02-17
MX339910B (es) 2016-06-15
CA2799883C (en) 2020-09-22
CA2799883A1 (en) 2013-06-22

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Legal Events

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B25A Requested transfer of rights approved

Owner name: EVONIK DEGUSSA GMBH (DE)

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 18/12/2012, OBSERVADAS AS CONDICOES LEGAIS.

B25D Requested change of name of applicant approved

Owner name: EVONIK OPERATIONS GMBH (DE)