BRPI0814781A8 - ''proteína, sequência de ácido nucleico, método para a produção de ácido itacônico, vetor, célula hospedeira, e, uso de um ácido cis-aconítico descarboxilase'' - Google Patents

''proteína, sequência de ácido nucleico, método para a produção de ácido itacônico, vetor, célula hospedeira, e, uso de um ácido cis-aconítico descarboxilase''

Info

Publication number
BRPI0814781A8
BRPI0814781A8 BRPI0814781A BRPI0814781A BRPI0814781A8 BR PI0814781 A8 BRPI0814781 A8 BR PI0814781A8 BR PI0814781 A BRPI0814781 A BR PI0814781A BR PI0814781 A BRPI0814781 A BR PI0814781A BR PI0814781 A8 BRPI0814781 A8 BR PI0814781A8
Authority
BR
Brazil
Prior art keywords
cis
production
host cell
vector
protein
Prior art date
Application number
BRPI0814781A
Other languages
English (en)
Inventor
Johanna Van Der Werf Maria
Petrus Maria Caspers Martinus
Van Luijk Nicole
Jan Punt Peter
Original Assignee
Tno
Dutch Dna Biotech B V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tno, Dutch Dna Biotech B V filed Critical Tno
Publication of BRPI0814781A2 publication Critical patent/BRPI0814781A2/pt
Publication of BRPI0814781A8 publication Critical patent/BRPI0814781A8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • C12P7/46—Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

PROTEÍNA, SEQUÊNCIA DE ÁCIDO NUCLEICO, MÉTODO PARA A PRODUÇÃO DE ÁCIDO ITACÔNICO, VETOR, CÉLULA HOSPEDEIRA, E, USO DE UM ÁCIDO CIS-ACONÍTICO DESCARBOXILASE. A invenção refere-se à produção de ácido itacônico em microorganismos por introdução em uma célula hospedeira apropriada de um gene codificando para a enzima ácido cis-aconítico descarboxilase, preferivelmente derivada de A. terreus. Outra parte da invenção são as células hospedeiras, preferivelmente de A. niger, providas com os genes acima mencionados.
BRPI0814781A 2007-07-20 2008-07-21 ''proteína, sequência de ácido nucleico, método para a produção de ácido itacônico, vetor, célula hospedeira, e, uso de um ácido cis-aconítico descarboxilase'' BRPI0814781A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07112895A EP2017344A1 (en) 2007-07-20 2007-07-20 Production of itaconic acid
PCT/NL2008/050499 WO2009014437A1 (en) 2007-07-20 2008-07-21 Production of itaconic acid

Publications (2)

Publication Number Publication Date
BRPI0814781A2 BRPI0814781A2 (pt) 2014-10-21
BRPI0814781A8 true BRPI0814781A8 (pt) 2017-01-31

Family

ID=38787782

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0814781A BRPI0814781A8 (pt) 2007-07-20 2008-07-21 ''proteína, sequência de ácido nucleico, método para a produção de ácido itacônico, vetor, célula hospedeira, e, uso de um ácido cis-aconítico descarboxilase''

Country Status (4)

Country Link
US (1) US8440436B2 (pt)
EP (2) EP2017344A1 (pt)
BR (1) BRPI0814781A8 (pt)
WO (1) WO2009014437A1 (pt)

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EP2425006A4 (en) 2009-04-30 2013-01-23 Genomatica Inc ORGANISMS FOR THE MANUFACTURE OF ISOPROPANOL, N-BUTANOL AND ISOBUTANOL
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KR20120036851A (ko) 2009-05-15 2012-04-18 게노마티카 인코포레이티드 사이클로헥사논의 제조를 위한 유기체
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BR112012028049A2 (pt) 2010-05-05 2015-11-24 Genomatica Inc organismo microbiano de ocorrência não natural e método para produzir butadieno, meio de cultura, butadieno biossintetizado, composição, produto químico orgânico, polímero e uso de butadieno biossintetizado
EP2607340B1 (en) 2010-07-26 2017-09-06 Genomatica, Inc. Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene
KR102043381B1 (ko) 2011-08-19 2019-11-11 게노마티카 인코포레이티드 2,4-펜타디에노에이트, 부타디엔, 프로필렌, 1,3-부탄디올 및 관련 알코올을 생합성하기 위한 미생물과 방법
CN103834582B (zh) * 2012-11-22 2016-04-27 中国科学院青岛生物能源与过程研究所 一种提高衣康酸发酵产量的菌株及其构建和利用菌株生产衣康酸的方法
CN104822832A (zh) * 2012-11-23 2015-08-05 帝斯曼知识产权资产管理有限公司 衣康酸和衣康酸甲酯生产
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CN111944706B (zh) * 2020-08-06 2022-06-03 中国科学院青岛生物能源与过程研究所 一种产衣康酸的重组土曲霉菌株及其构建方法与应用
CN112011469B (zh) * 2020-08-26 2022-07-05 中国科学院青岛生物能源与过程研究所 一种产反式乌头酸的重组土曲霉菌株及其构建方法与应用
CN112011468B (zh) * 2020-08-26 2022-07-05 中国科学院青岛生物能源与过程研究所 一种产反式乌头酸的重组土曲霉及其制备方法与应用
CN112029671B (zh) * 2020-08-26 2022-07-05 中国科学院青岛生物能源与过程研究所 一种产反式乌头酸的重组土曲霉菌株及其制备方法与应用
CN112011470B (zh) * 2020-08-26 2022-07-05 中国科学院青岛生物能源与过程研究所 一种产反式乌头酸的基因工程菌及其构建方法与应用
KR102682476B1 (ko) * 2021-07-19 2024-07-04 포항공과대학교 산학협력단 이타콘산을 생산하는 신규 대사 경로 및 이를 이용한 이타콘산의 생산 방법
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Also Published As

Publication number Publication date
US8440436B2 (en) 2013-05-14
EP2183367A1 (en) 2010-05-12
EP2017344A8 (en) 2009-05-13
EP2017344A1 (en) 2009-01-21
US20100311132A1 (en) 2010-12-09
BRPI0814781A2 (pt) 2014-10-21
WO2009014437A1 (en) 2009-01-29
EP2183367B1 (en) 2019-05-22

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Owner name: DUTCH DNA BIOTECH B.V. (NL)

B25A Requested transfer of rights approved

Owner name: DUTCH DNA BIOTECH B.V. (NL)

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]