AR072531A1 - SENAL DE POLIADENILACIoN - Google Patents

SENAL DE POLIADENILACIoN

Info

Publication number
AR072531A1
AR072531A1 ARP090102796A ARP090102796A AR072531A1 AR 072531 A1 AR072531 A1 AR 072531A1 AR P090102796 A ARP090102796 A AR P090102796A AR P090102796 A ARP090102796 A AR P090102796A AR 072531 A1 AR072531 A1 AR 072531A1
Authority
AR
Argentina
Prior art keywords
regulatory elements
polyadenilation
sign
addition
polypeptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
ARP090102796A
Other languages
English (en)
Inventor
Barbara Enenkel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH Co KG
Original Assignee
Boehringer Ingelheim Pharma GmbH Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma GmbH Co KG filed Critical Boehringer Ingelheim Pharma GmbH Co KG
Publication of AR072531A1 publication Critical patent/AR072531A1/es
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Elementos reguladores así como a vectores y células relacionadas. Además, métodos de mejora de la expresion de polipéptidos a partir de ácidos nucleicos tales como genes clonados y a la produccion de diversos polipéptidos en células hospedadoras usando dichos elementos reguladores. Además, usos de dichos elementos reguladores como aislantes, en terapia génica o para líneas celulares hospedadoras. Kit.
ARP090102796A 2008-07-23 2009-07-22 SENAL DE POLIADENILACIoN Pending AR072531A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP08161029 2008-07-23

Publications (1)

Publication Number Publication Date
AR072531A1 true AR072531A1 (es) 2010-09-01

Family

ID=40085605

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP090102796A Pending AR072531A1 (es) 2008-07-23 2009-07-22 SENAL DE POLIADENILACIoN

Country Status (25)

Country Link
US (2) US8466271B2 (es)
EP (1) EP2310501B1 (es)
JP (1) JP5481478B2 (es)
KR (1) KR101837925B1 (es)
CN (1) CN102165060B (es)
AR (1) AR072531A1 (es)
AU (1) AU2009273239B2 (es)
BR (1) BRPI0915989A2 (es)
CA (1) CA2724908C (es)
CY (1) CY1114483T1 (es)
DK (1) DK2310501T3 (es)
EA (1) EA201100225A1 (es)
ES (1) ES2421152T3 (es)
HK (1) HK1156663A1 (es)
HR (1) HRP20130888T1 (es)
IL (1) IL208700A (es)
MX (1) MX2011000535A (es)
MY (1) MY156855A (es)
NZ (1) NZ589268A (es)
PL (1) PL2310501T3 (es)
PT (1) PT2310501E (es)
SG (2) SG188882A1 (es)
SI (1) SI2310501T1 (es)
TW (1) TW201011104A (es)
WO (1) WO2010010107A1 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2310501T3 (da) 2008-07-23 2013-08-26 Boehringer Ingelheim Pharma Nye regulatoriske elementer
KR100882240B1 (ko) * 2008-09-11 2009-02-25 (주)플러스텍 질화물 반도체 발광소자 및 제조방법
WO2014102101A1 (en) 2012-12-31 2014-07-03 Boehringer Ingelheim International Gmbh Novel intron sequences
EP2938726B1 (en) 2012-12-31 2017-09-27 Boehringer Ingelheim International GmbH Heterologous intron within a signal peptide
CN104293737B (zh) * 2014-09-16 2017-06-13 太原博奥特生物技术有限公司 一种包含表达功能性重组人凝血因子ⅶ载体的宿主细胞及其高水平表达方法
CN109790550B (zh) 2016-09-20 2024-02-09 勃林格殷格翰动物保健有限公司 新颖的启动子
AU2017329669A1 (en) 2016-09-20 2019-03-21 Boehringer Ingelheim Vetmedica Gmbh New EHV insertion site ORF70
WO2018054822A1 (en) 2016-09-20 2018-03-29 Boehringer Ingelheim Vetmedica Gmbh New swine influenza vaccine
UY37405A (es) 2016-09-20 2018-03-23 Boehringer Ingelheim Vetmedica Gmbh Vectores de adenovirus canino
BR112019021595A2 (pt) * 2017-04-18 2020-05-12 Glaxosmithkline Intellectual Property Development Limited Célula produtora de vírus adeno-associado, vetor de ácido nucleico, métodos para produzir uma linhagem de células de empacotamento estável de vírus adeno-associado e uma partícula de vetor de vírus adeno-associado com defeito de replicação, célula de empacotamento de vírus adeno-associado, e, partícula de vetor de vírus adeno-associado com defeito de replicação.
GB201706121D0 (en) * 2017-04-18 2017-05-31 Glaxosmithkline Ip Dev Ltd Stable cell lines for retroviral production
EP3675903A1 (en) 2017-09-23 2020-07-08 Boehringer Ingelheim Vetmedica GmbH Paramyxoviridae expression system
CN111712575B (zh) 2018-02-23 2024-07-19 勃林格殷格翰动物保健有限公司 表达外源猫副粘病毒基因的重组病毒载体系统及由其制备的疫苗
JP7245260B2 (ja) 2018-03-19 2023-03-23 ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハー Ｅｈｖ挿入部位ｕｌ４３
EA202092164A1 (ru) 2018-03-19 2021-02-10 Бёрингер Ингельхайм Ветмедика Гмбх Новый ehv с инактивированным ul18 и/или ul8
US10905758B2 (en) 2018-09-20 2021-02-02 Boehringer Ingelheim Vetmedica Gmbh Intranasal vector vaccine against porcine epidemic diarrhea
CN109486859A (zh) * 2018-11-21 2019-03-19 新乡医学院 人工合成的polyA、哺乳动物细胞重组表达载体、哺乳动物宿主细胞、表达方法及应用
CN116096904A (zh) * 2019-12-31 2023-05-09 天鹅生物疗法有限公司 改进的aav-abcd1构建体和用于治疗或预防肾上腺脑白质营养不良(ald)和/或肾上腺脊髓神经病(amn)的用途
EP4243866A1 (en) 2020-11-13 2023-09-20 Boehringer Ingelheim Vetmedica GmbH New feline herpes virus vaccine

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3584341D1 (de) * 1984-08-24 1991-11-14 Upjohn Co Rekombinante dna-verbindungen und expression von polypeptiden wie tpa.
FR2629098B1 (fr) * 1988-03-23 1990-08-10 Rhone Poulenc Agrochimie Gene chimerique de resistance herbicide
US7351813B2 (en) * 2000-06-20 2008-04-01 The Board Of Trustees Of The Leland Stanford Junior University Liver-specific gene expression cassettes, and methods of use
UY26317A1 (es) * 2000-08-30 2000-10-31 Alfonso Cayota Carlos Pritsch Sistema de produccion de trombopoyetina humana por celulas de mamiferos en cultivo
AU2004279991B2 (en) 2003-10-10 2010-11-25 Powderject Vaccines, Inc. Nucleic acid constructs
WO2005073384A2 (en) * 2004-01-28 2005-08-11 Research Development Foundation Human soluble neuropilin-1 primary polyadenylation signal and uses thereof
US20060281703A1 (en) 2005-05-19 2006-12-14 Schering Aktiengesellschaft Treatment of disease using an improved regulated expression system
DK2310501T3 (da) 2008-07-23 2013-08-26 Boehringer Ingelheim Pharma Nye regulatoriske elementer

Also Published As

Publication number Publication date
AU2009273239B2 (en) 2015-07-23
AU2009273239A1 (en) 2010-01-28
DK2310501T3 (da) 2013-08-26
SG192541A1 (en) 2013-08-30
TW201011104A (en) 2010-03-16
EP2310501A1 (en) 2011-04-20
CN102165060A (zh) 2011-08-24
CN102165060B (zh) 2013-07-17
HK1156663A1 (en) 2012-06-15
CA2724908C (en) 2017-03-14
CA2724908A1 (en) 2010-01-28
JP2011526795A (ja) 2011-10-20
MY156855A (en) 2016-04-15
KR101837925B1 (ko) 2018-03-13
SG188882A1 (en) 2013-04-30
US8975391B2 (en) 2015-03-10
US8466271B2 (en) 2013-06-18
EA201100225A1 (ru) 2011-08-30
WO2010010107A1 (en) 2010-01-28
US20110312029A1 (en) 2011-12-22
US20130177943A1 (en) 2013-07-11
CY1114483T1 (el) 2016-10-05
PL2310501T3 (pl) 2013-12-31
MX2011000535A (es) 2011-02-22
IL208700A0 (en) 2010-12-30
JP5481478B2 (ja) 2014-04-23
PT2310501E (pt) 2013-07-18
HRP20130888T1 (hr) 2013-10-25
ES2421152T3 (es) 2013-08-29
SI2310501T1 (sl) 2013-10-30
BRPI0915989A2 (pt) 2019-03-26
KR20110031912A (ko) 2011-03-29
EP2310501B1 (en) 2013-07-03
IL208700A (en) 2013-12-31
NZ589268A (en) 2012-06-29

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