AR079821A1 - Cepas y metodo para la produccion de metionina - Google Patents

Cepas y metodo para la produccion de metionina

Info

Publication number
AR079821A1
AR079821A1 ARP100105026A ARP100105026A AR079821A1 AR 079821 A1 AR079821 A1 AR 079821A1 AR P100105026 A ARP100105026 A AR P100105026A AR P100105026 A ARP100105026 A AR P100105026A AR 079821 A1 AR079821 A1 AR 079821A1
Authority
AR
Argentina
Prior art keywords
production
metionin
cepas
transformation
threonine
Prior art date
Application number
ARP100105026A
Other languages
English (en)
Original Assignee
Metabolic Explorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metabolic Explorer Sa filed Critical Metabolic Explorer Sa
Publication of AR079821A1 publication Critical patent/AR079821A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
    • C12N9/1014—Hydroxymethyl-, formyl-transferases (2.1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/02—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/12—Methionine; Cysteine; Cystine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y201/00—Transferases transferring one-carbon groups (2.1)
    • C12Y201/02—Hydroxymethyl-, formyl- and related transferases (2.1.2)
    • C12Y201/02001—Glycine hydroxymethyltransferase (2.1.2.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y403/00—Carbon-nitrogen lyases (4.3)
    • C12Y403/01—Ammonia-lyases (4.3.1)
    • C12Y403/01019—Threonine ammonia-lyase (4.3.1.19)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

La presente se refiere a un método para la produccion de metionina utilizando cepas modificadas con transformacion atenuada de treonina. Esto se puede lograr mediante la reduccion de la transformacion de treonina en glicina, y/o reduciendo su transformacion en alfa-cetobutirato. La solicitud se refiere también a las cepas modificadas con la transformacion atenuada de treonina.
ARP100105026A 2009-12-30 2010-12-30 Cepas y metodo para la produccion de metionina AR079821A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP09306349 2009-12-30

Publications (1)

Publication Number Publication Date
AR079821A1 true AR079821A1 (es) 2012-02-22

Family

ID=42562397

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP100105026A AR079821A1 (es) 2009-12-30 2010-12-30 Cepas y metodo para la produccion de metionina

Country Status (11)

Country Link
US (1) US9382561B2 (es)
EP (1) EP2519637A2 (es)
JP (1) JP5922036B2 (es)
KR (1) KR101915819B1 (es)
CN (1) CN102782137B (es)
AR (1) AR079821A1 (es)
BR (1) BR112012016908B1 (es)
IN (1) IN2012DN06442A (es)
MX (1) MX2012007717A (es)
MY (1) MY172018A (es)
WO (1) WO2011080301A2 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101915819B1 (ko) * 2009-12-30 2018-11-06 에보니크 데구사 게엠베하 메티오닌 생산을 위한 균주 및 방법
CN103981206B (zh) * 2014-06-06 2016-03-02 中国科学院天津工业生物技术研究所 一种筛选高产苏氨酸菌株的方法
MY194223A (en) 2014-09-01 2022-11-22 Evonik Operations Gmbh Method and microorganism for methionine production by fermentation with improved methionine efflux
CN104372035B (zh) * 2014-10-17 2017-10-31 湖南宝利士生物技术有限公司 合成高纯2‑酮酸盐的方法
CN104313071B (zh) * 2014-10-17 2018-04-13 湖南宝利士生物技术有限公司 高纯L‑α‑氨基酸的生物合成方法
CA2975011C (en) * 2015-01-27 2023-11-07 Danmarks Tekniske Universitet Genetically modified microorganisms having improved tolerance towards l-serine
CN108026516A (zh) 2015-08-07 2018-05-11 赢创德固赛有限公司 通过发酵的蛋白硫代羧化物依赖性l-甲硫氨酸生产
ES2748226T3 (es) 2015-11-27 2020-03-16 Evonik Operations Gmbh Procedimiento de producción de L-metionina
EP3296404A1 (en) 2016-09-15 2018-03-21 Evonik Degussa GmbH Modified microorganism for production of methionine
KR20200010285A (ko) * 2017-05-19 2020-01-30 지머젠 인코포레이티드 증가된 nadph를 유도하는 생합성 경로의 게놈 공학
CN109402098B (zh) * 2018-11-06 2021-09-17 王喆明 苏氨酸醛缩酶、突变体及其在制备取代苯丝氨酸衍生物中的应用
US20200393381A1 (en) * 2019-06-12 2020-12-17 Henkel IP & Holding GmbH Method And System For Determining The Presence Of An Odorous Material On A Fabric
CN112779200B (zh) * 2021-01-12 2022-07-08 浙江工业大学 高产l-甲硫氨酸的基因工程菌及其构建与应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000157267A (ja) 1998-11-24 2000-06-13 Ajinomoto Co Inc 変異型ｍｅｔＪ遺伝子及びＬ−メチオニンの製造法
JPWO2002097086A1 (ja) 2001-05-29 2005-04-07 協和醗酵工業株式会社 工業的生産に有用な微生物
DE10305774A1 (de) * 2003-02-06 2004-08-26 Consortium für elektrochemische Industrie GmbH Verfahren zur fermentativen Herstellung von L-Methionin
JP2006517796A (ja) 2003-02-18 2006-08-03 メタボリック エクスプローラー 代謝経路の生成または改変を可能とする進化した微生物の生産方法
DE10311399A1 (de) * 2003-03-13 2004-09-23 Forschungszentrum Jülich GmbH Nukleotidsequenzen coryneformer Bakterien codierend für am L-Serinstoffwechsel beteiligte Proteine sowie Verfahren zur mikrobiellen Herstellung von L-Serin
WO2005111202A1 (en) 2004-05-12 2005-11-24 Metabolic Explorer Recombinant enzyme with altered feedback sensitivity
NO331033B1 (no) * 2005-07-07 2011-09-19 I P Huse As Anordning for transport av kjetting.
WO2007020295A2 (en) 2005-08-18 2007-02-22 Basf Ag Microorganisms with increased efficiency for methionine synthesis
JP5172697B2 (ja) * 2006-01-04 2013-03-27 メタボリック エクスプローラー 硫酸透過酵素の発現が増強された微生物を用いてメチオニンおよびその前駆体ホモセリンまたはスクシニルホモセリンを製造するための方法
KR100905381B1 (ko) * 2006-07-28 2009-06-30 씨제이제일제당 (주) Ｌ-메치오닌 전구체 생산 균주 및 상기 ｌ-메치오닌전구체로부터의 ｌ-메치오닌 및 유기산의 생산방법
BRPI0807760A2 (pt) * 2007-02-19 2014-06-17 Evonik Degussa Gmbh Bactérias corineformes com atividade de formato-thf-sintetase e/ou atividade de clivagem de glicina
KR100858913B1 (ko) * 2007-03-09 2008-09-17 한국과학기술원 부위특이적 변이에 의해 제조된 고수율의 ｌ－쓰레오닌생산균주 및 이를 이용한 ｌ－쓰레오닌의 제조방법
WO2009043372A1 (en) 2007-10-02 2009-04-09 Metabolic Explorer Increasing methionine yield
WO2010020290A1 (en) * 2008-08-22 2010-02-25 Metabolic Explorer Producing methionine without n-acetyl methionine
KR101915819B1 (ko) * 2009-12-30 2018-11-06 에보니크 데구사 게엠베하 메티오닌 생산을 위한 균주 및 방법

Also Published As

Publication number Publication date
US20120288904A1 (en) 2012-11-15
CN102782137A (zh) 2012-11-14
EP2519637A2 (en) 2012-11-07
KR101915819B1 (ko) 2018-11-06
JP2013516162A (ja) 2013-05-13
BR112012016908B1 (pt) 2020-03-31
WO2011080301A2 (en) 2011-07-07
CN102782137B (zh) 2016-01-06
US9382561B2 (en) 2016-07-05
KR20120114325A (ko) 2012-10-16
JP5922036B2 (ja) 2016-05-24
WO2011080301A3 (en) 2012-04-12
MY172018A (en) 2019-11-12
IN2012DN06442A (es) 2015-10-09
BR112012016908A2 (pt) 2015-09-15
MX2012007717A (es) 2012-07-25

Similar Documents

Publication Publication Date Title
AR079821A1 (es) Cepas y metodo para la produccion de metionina
EP3027758A4 (en) Process for the enzymatic conversion of lignocellulosic biomass
BRPI1012204A2 (pt) método de pré-tratamento de biomassa para preparar bioetanol
BR112013033711A2 (pt) processo para fermentar singás e para iniciar fermentador principal para fermentação de singás
CL2013003792A1 (es) Metodo para detener el crecimiento celular en un cultivo celular de mamíferos que expresan una proteina recombinante.
CL2012000590A1 (es) Proceso para preparar w-transaminasa (r)-selectiva.
MX353579B (es) Organoide hepatico, sus usos y metodo de cultivo para obtenerlos.
CR20120011A (es) Inhibidores de bace
CR20120184A (es) Anticuerpos monoclonales frente a progastrina y su usos
CL2013002068A1 (es) Linea celular de ratón con genes inactivados nav1.7 global viable; metodo para generar ratón con dichos genes inactivados; hibridoma.
UY34577A (es) Método para estabilizar fibra de lignina y su posterior conversión en fibra de carbono
UY35517A (es) Un procedimiento para aumentar la formación de ácido piroglutamico de una proteína
BRPI1012736A2 (pt) segmento de fuselagem e processo para produzir o segmento de fuselagem
BRPI0919388A2 (pt) ácido succínico e método para produzir o mesmo.
CL2014001746A1 (es) Procedimiento de remojo previo mejorado para la conversion de biomasa lignocelulosica
BRPI0924019A2 (pt) método de fermentação e aparelhos adaptados para o método
CR10905A (es) Proceso para producir biomasa y proteinas por microalgas
CL2012003491A1 (es) Compuesto derivado de dihidropirrol sustituidos; proceso para preparar dichos derivados en forma estereoselectiva.
BR112018010387A8 (pt) levedura geneticamente modificada e processo para fabricar etanol
MX2011008275A (es) Plantas que tienen mejores rasgos relacionados con el rendimiento y un metodo para producirlas.
IN2014DN03464A (es)
BRPI1009574A2 (pt) Método para reduzir a produção de co2 em um processo de fermentação para produzir um álcool, e, microorganismo modificado.
BR112013002752A2 (pt) processo para a conversão de biomassa de origem vegetal, e um processo de combustão
MX2011012623A (es) Construcciones de casb7439.
BR112013019285A2 (pt) aparelho de fermentação que usa biomassa como matéria-prima.

Legal Events

Date Code Title Description
FB Suspension of granting procedure