JP2015509366A5 - - Google Patents

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JP2015509366A5
JP2015509366A5 JP2014558252A JP2014558252A JP2015509366A5 JP 2015509366 A5 JP2015509366 A5 JP 2015509366A5 JP 2014558252 A JP2014558252 A JP 2014558252A JP 2014558252 A JP2014558252 A JP 2014558252A JP 2015509366 A5 JP2015509366 A5 JP 2015509366A5
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mirna
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JP2014558252A
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Priority claimed from PCT/IB2013/051429 external-priority patent/WO2013124816A2/en
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JP2014558252A 2012-02-22 2013-02-21 神経幹細胞および運動ニューロンの生成 Pending JP2015509366A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261601596P 2012-02-22 2012-02-22
US61/601,596 2012-02-22
PCT/IB2013/051429 WO2013124816A2 (en) 2012-02-22 2013-02-21 Generation of neural stem cells and motor neurons

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JP2017232724A Division JP6526164B2 (ja) 2012-02-22 2017-12-04 神経幹細胞および運動ニューロンの生成

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JP2015509366A JP2015509366A (ja) 2015-03-30
JP2015509366A5 true JP2015509366A5 (enExample) 2016-04-14

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JP2014558252A Pending JP2015509366A (ja) 2012-02-22 2013-02-21 神経幹細胞および運動ニューロンの生成
JP2017232724A Expired - Fee Related JP6526164B2 (ja) 2012-02-22 2017-12-04 神経幹細胞および運動ニューロンの生成

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US (3) US9803175B2 (enExample)
EP (2) EP2844745A2 (enExample)
JP (2) JP2015509366A (enExample)
WO (1) WO2013124816A2 (enExample)

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KR102113646B1 (ko) 2017-03-30 2020-05-22 울산대학교 산학협력단 신경줄기세포 사멸 억제 효과를 가지는 miR-383-5p 억제제를 유효성분으로 포함하는 퇴행성 신경질환 예방 또는 치료용 조성물
KR101964748B1 (ko) 2017-06-01 2019-04-03 울산대학교 산학협력단 신경줄기세포 사멸 억제 효과를 가지는 miR-141-5p 억제제를 유효성분으로 포함하는 퇴행성 신경질환 예방 또는 치료용 조성물
CN107982537A (zh) * 2017-11-17 2018-05-04 厦门大学 针对microRNA-155的治疗性药物及其应用
KR20190105334A (ko) 2018-03-05 2019-09-17 울산대학교 산학협력단 신경줄기세포 사멸 억제 효과를 가지는 miR-125a-5p 억제제를 유효성분으로 포함하는 퇴행성 신경질환 치료용 조성물
EP3587575A1 (en) * 2018-06-26 2020-01-01 Institut National de la Santé et de la Recherche Medicale Mirna mir-218 and use thereof for stimulating mesenchymal stem cells
WO2020037254A1 (en) * 2018-08-17 2020-02-20 City Of Hope Compounds of chemically modified oligonucleotides and methods of use thereof
CN109609554B (zh) * 2018-11-29 2022-03-15 南方医科大学 一种mir338基因沉默的脐带间充质干细胞及其制备方法和应用
WO2021051154A1 (en) * 2019-09-16 2021-03-25 Genieus Genomics Pty Ltd "biomarkers for neurodegenerative diseases"
WO2021072163A1 (en) * 2019-10-09 2021-04-15 The Regents Of The University Of California Compositions and methods for reprogramming age-restricted non-neuronal cells
TW202134437A (zh) * 2019-11-29 2021-09-16 比利時商諾瓦迪生物科學公司 用於預防及治療組織疾病之基於miRNA之醫藥組成物及其用途
CN111850047B (zh) * 2020-07-28 2022-08-12 枣庄学院 一种miR-16与miR-30c联合表达载体及其构建方法与应用
RU2742449C1 (ru) * 2020-09-30 2021-02-05 федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр онкологии" Министерства здравоохранения Российской Федерации Способ ортотопической трансплантации фрагмента глиобластомы головного мозга человека в область cortex parietalis головного мозга иммунодефицитных мышей
US20230372403A1 (en) * 2020-10-09 2023-11-23 The Regents Of The University Of California Immunoengineering biomaterials for treatment of graft rejection
KR102791586B1 (ko) 2021-11-23 2025-04-08 재단법인 아산사회복지재단 miR-92b-5p 억제제를 유효성분으로 포함하는 퇴행성 뇌신경질환 예방 또는 치료용 조성물
CN116333994A (zh) * 2021-12-07 2023-06-27 上海鲸奇生物科技有限公司 非编码rna介导的神经性疾病治疗
WO2023238948A1 (ja) * 2022-06-09 2023-12-14 国立大学法人九州大学 miRNAを含む新規脳神経新生促進剤

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JP2015509366A (ja) 2012-02-22 2015-03-30 ブレインステム バイオテック リミテッド 神経幹細胞および運動ニューロンの生成
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JP2015510401A (ja) 2012-02-22 2015-04-09 ブレインステム バイオテック リミテッド ヒト疾患のインビトロモデル化および細胞に基づく治療のための間葉系幹細胞ならびにそのバンク

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