JP2015502138A5 - - Google Patents
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- JP2015502138A5 JP2015502138A5 JP2014535228A JP2014535228A JP2015502138A5 JP 2015502138 A5 JP2015502138 A5 JP 2015502138A5 JP 2014535228 A JP2014535228 A JP 2014535228A JP 2014535228 A JP2014535228 A JP 2014535228A JP 2015502138 A5 JP2015502138 A5 JP 2015502138A5
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- Prior art keywords
- sequence
- seq
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- monoclonal antibody
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- 108010045030 monoclonal antibodies Proteins 0.000 claims 30
- 102000005614 monoclonal antibodies Human genes 0.000 claims 29
- 102000004965 antibodies Human genes 0.000 claims 13
- 108090001123 antibodies Proteins 0.000 claims 13
- 201000010099 disease Diseases 0.000 claims 10
- 101710043957 CEACAM1 Proteins 0.000 claims 5
- 102100011828 CEACAM1 Human genes 0.000 claims 5
- 239000000203 mixture Substances 0.000 claims 5
- 102100002977 CDR1 Human genes 0.000 claims 4
- 230000000118 anti-eoplastic Effects 0.000 claims 3
- 229920000023 polynucleotide Polymers 0.000 claims 3
- 239000002157 polynucleotide Substances 0.000 claims 3
- 230000033115 angiogenesis Effects 0.000 claims 2
- 229960000070 antineoplastic Monoclonal antibodies Drugs 0.000 claims 2
- 210000004027 cells Anatomy 0.000 claims 2
- 229960000060 monoclonal antibodies Drugs 0.000 claims 2
- 230000002062 proliferating Effects 0.000 claims 2
- 230000004083 survival Effects 0.000 claims 2
- 210000004881 tumor cells Anatomy 0.000 claims 2
- 101710043954 CEACAM3 Proteins 0.000 claims 1
- 102100011836 CEACAM3 Human genes 0.000 claims 1
- 101710043956 CEACAM5 Proteins 0.000 claims 1
- 102100011842 CEACAM5 Human genes 0.000 claims 1
- 210000004698 Lymphocytes Anatomy 0.000 claims 1
- 229920001850 Nucleic acid sequence Polymers 0.000 claims 1
- 206010047461 Viral infection Diseases 0.000 claims 1
- 208000001756 Virus Disease Diseases 0.000 claims 1
- 230000004913 activation Effects 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 102000038129 antigens Human genes 0.000 claims 1
- 108091007172 antigens Proteins 0.000 claims 1
- 239000002246 antineoplastic agent Substances 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 239000000969 carrier Substances 0.000 claims 1
- 108091006028 chimera Proteins 0.000 claims 1
- 230000001472 cytotoxic Effects 0.000 claims 1
- 231100000433 cytotoxic Toxicity 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 230000005012 migration Effects 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 230000017613 viral reproduction Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IL2011/000808 WO2013054320A1 (en) | 2011-10-11 | 2011-10-11 | Antibodies to carcinoembryonic antigen-related cell adhesion molecule (ceacam) |
| ILPCT/IL2011/000808 | 2011-10-11 | ||
| PCT/IL2012/050402 WO2013054331A1 (en) | 2011-10-11 | 2012-10-10 | Antibodies to carcinoembryonic antigen-related cell adhesion molecule (ceacam) |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015502138A JP2015502138A (ja) | 2015-01-22 |
| JP2015502138A5 true JP2015502138A5 (ko) | 2015-12-03 |
| JP6170926B2 JP6170926B2 (ja) | 2017-07-26 |
Family
ID=48081453
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014535228A Active JP6170926B2 (ja) | 2011-10-11 | 2012-10-10 | 癌胎児抗原関連細胞接着分子（ｃｅａｃａｍ）に対する抗体 |
Country Status (16)
| Country | Link |
|---|---|
| US (3) | US9771431B2 (ko) |
| EP (2) | EP3360899B1 (ko) |
| JP (1) | JP6170926B2 (ko) |
| KR (1) | KR102189409B1 (ko) |
| CN (1) | CN103987729B (ko) |
| AU (1) | AU2012322272C1 (ko) |
| BR (1) | BR112014008893B1 (ko) |
| CA (1) | CA2851762C (ko) |
| ES (2) | ES2661488T3 (ko) |
| HK (1) | HK1199646A1 (ko) |
| IL (1) | IL231931B (ko) |
| IN (1) | IN2014MN00873A (ko) |
| LT (1) | LT2744829T (ko) |
| PL (2) | PL3360899T3 (ko) |
| RU (1) | RU2650869C2 (ko) |
| WO (2) | WO2013054320A1 (ko) |
Families Citing this family (111)
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| JP6919118B2 (ja) | 2014-08-14 | 2021-08-18 | ノバルティス アーゲー | ＧＦＲα−４キメラ抗原受容体を用いる癌の治療 |
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| PL3194443T3 (pl) | 2014-09-17 | 2022-01-31 | Novartis Ag | Nakierowywanie komórek cytotoksycznych za pośrednictwem receptorów chimerycznych do immunoterapii adoptywnej |
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| EP3344996A2 (en) | 2015-09-03 | 2018-07-11 | The Trustees Of The University Of Pennsylvania | Biomarkers predictive of cytokine release syndrome |
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| US11365252B2 (en) | 2016-07-20 | 2022-06-21 | University Of Utah Research Foundation | CD229 CAR T cells and methods of use thereof |
| WO2018019380A1 (de) * | 2016-07-28 | 2018-02-01 | Universität Duisburg-Essen | Immunstimulatorische anti-ceacam1-antikörper |
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2011
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- 2012-10-10 PL PL17200104.2T patent/PL3360899T3/pl unknown
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