JP2015227351A5 - - Google Patents

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Publication number
JP2015227351A5
JP2015227351A5 JP2015140309A JP2015140309A JP2015227351A5 JP 2015227351 A5 JP2015227351 A5 JP 2015227351A5 JP 2015140309 A JP2015140309 A JP 2015140309A JP 2015140309 A JP2015140309 A JP 2015140309A JP 2015227351 A5 JP2015227351 A5 JP 2015227351A5
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Japan
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pharmaceutical composition
composition according
antimetabolite
cancer
drug
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JP2015140309A
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English (en)
Japanese (ja)
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JP2015227351A (ja
JP6352863B2 (ja
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Publication of JP2015227351A publication Critical patent/JP2015227351A/ja
Publication of JP2015227351A5 publication Critical patent/JP2015227351A5/ja
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Publication of JP6352863B2 publication Critical patent/JP6352863B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2015140309A 2004-03-15 2015-07-14 Sns−595、及びその使用方法 Expired - Fee Related JP6352863B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55357804P 2004-03-15 2004-03-15
US60/553,578 2004-03-15

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2014091125A Division JP5856644B2 (ja) 2004-03-15 2014-04-25 Sns−595、及びその使用方法

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016248041A Division JP2017095471A (ja) 2004-03-15 2016-12-21 Sns−595、及びその使用方法

Publications (3)

Publication Number Publication Date
JP2015227351A JP2015227351A (ja) 2015-12-17
JP2015227351A5 true JP2015227351A5 (enrdf_load_stackoverflow) 2016-02-04
JP6352863B2 JP6352863B2 (ja) 2018-07-04

Family

ID=34993432

Family Applications (9)

Application Number Title Priority Date Filing Date
JP2007503972A Expired - Fee Related JP5096913B2 (ja) 2004-03-15 2005-03-14 Sns−595、及びその使用方法
JP2007503987A Expired - Fee Related JP5317472B2 (ja) 2004-03-15 2005-03-14 Sns−595、及びその使用方法
JP2011135675A Pending JP2011225590A (ja) 2004-03-15 2011-06-17 Sns−595、及びその使用方法
JP2012036919A Pending JP2012140442A (ja) 2004-03-15 2012-02-23 Sns−595、及びその使用方法
JP2014091125A Expired - Fee Related JP5856644B2 (ja) 2004-03-15 2014-04-25 Sns−595、及びその使用方法
JP2014180862A Expired - Fee Related JP6261477B2 (ja) 2004-03-15 2014-09-05 Sns−595、及びその使用方法
JP2015140309A Expired - Fee Related JP6352863B2 (ja) 2004-03-15 2015-07-14 Sns−595、及びその使用方法
JP2016248041A Pending JP2017095471A (ja) 2004-03-15 2016-12-21 Sns−595、及びその使用方法
JP2018038834A Pending JP2018119977A (ja) 2004-03-15 2018-03-05 Sns−595、及びその使用方法

Family Applications Before (6)

Application Number Title Priority Date Filing Date
JP2007503972A Expired - Fee Related JP5096913B2 (ja) 2004-03-15 2005-03-14 Sns−595、及びその使用方法
JP2007503987A Expired - Fee Related JP5317472B2 (ja) 2004-03-15 2005-03-14 Sns−595、及びその使用方法
JP2011135675A Pending JP2011225590A (ja) 2004-03-15 2011-06-17 Sns−595、及びその使用方法
JP2012036919A Pending JP2012140442A (ja) 2004-03-15 2012-02-23 Sns−595、及びその使用方法
JP2014091125A Expired - Fee Related JP5856644B2 (ja) 2004-03-15 2014-04-25 Sns−595、及びその使用方法
JP2014180862A Expired - Fee Related JP6261477B2 (ja) 2004-03-15 2014-09-05 Sns−595、及びその使用方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2016248041A Pending JP2017095471A (ja) 2004-03-15 2016-12-21 Sns−595、及びその使用方法
JP2018038834A Pending JP2018119977A (ja) 2004-03-15 2018-03-05 Sns−595、及びその使用方法

Country Status (23)

Country Link
US (12) US7989468B2 (enrdf_load_stackoverflow)
EP (4) EP1725233B1 (enrdf_load_stackoverflow)
JP (9) JP5096913B2 (enrdf_load_stackoverflow)
KR (1) KR101169825B1 (enrdf_load_stackoverflow)
CN (5) CN103083316B (enrdf_load_stackoverflow)
AT (2) ATE451924T1 (enrdf_load_stackoverflow)
AU (3) AU2005222622B2 (enrdf_load_stackoverflow)
BR (1) BRPI0508700A (enrdf_load_stackoverflow)
CA (3) CA2954578A1 (enrdf_load_stackoverflow)
CY (2) CY1109741T1 (enrdf_load_stackoverflow)
DE (2) DE602005018333D1 (enrdf_load_stackoverflow)
DK (3) DK1729770T3 (enrdf_load_stackoverflow)
ES (3) ES2566973T3 (enrdf_load_stackoverflow)
HU (1) HUE027266T2 (enrdf_load_stackoverflow)
IL (2) IL177946A (enrdf_load_stackoverflow)
MX (2) MX349188B (enrdf_load_stackoverflow)
NO (3) NO338058B1 (enrdf_load_stackoverflow)
NZ (2) NZ549557A (enrdf_load_stackoverflow)
PL (3) PL1725233T3 (enrdf_load_stackoverflow)
PT (2) PT1729770E (enrdf_load_stackoverflow)
SI (2) SI1725233T1 (enrdf_load_stackoverflow)
WO (2) WO2005089757A1 (enrdf_load_stackoverflow)
ZA (1) ZA200607248B (enrdf_load_stackoverflow)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE027266T2 (en) 2004-03-15 2016-10-28 Sunesis Pharmaceuticals Inc Use of SNS-595 for treating leukemia
NZ553746A (en) 2004-09-17 2010-06-25 Cylene Pharmaceuticals Inc Quinolone analogs as cell proliferation inhibitors
US7652134B2 (en) 2004-09-17 2010-01-26 Cylene Pharmaceuticals, Inc. Methods for converting quinolone esters into quinolone amides
EP1926372A2 (en) * 2005-08-19 2008-06-04 Cylene Pharmaceuticals, Inc. HUMAN RIBOSOMAL DNA(rDNA) AND RIBOSOMAL RNA (rRNA) NUCLEIC ACIDS AND USES THEREOF
US8580814B2 (en) * 2006-04-03 2013-11-12 Sunesis Pharmaceuticals, Inc. Methods of using (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4- oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer
KR20140057409A (ko) * 2005-09-02 2014-05-12 선에시스 파마슈티컬스 인코포레이티드 암 치료를 위한 (+)-1,4-디히드로-7-[(3s,4s)-3-메톡시-4-(메틸아미노)-1-피롤리디닐]-4-옥소-1-(2-티아졸릴)-1,8-나프티리딘-3-카르복실산의 사용 방법
KR20080041298A (ko) * 2005-09-02 2008-05-09 선에시스 파마슈티컬스 인코포레이티드 암 치료를 위한(+)-1,4-디히드로-7-[(3s,4s)-3-메톡시-4-(메틸아미노)-1-피롤리디닐]-4-옥소-1-(2-티아졸릴)-1,8-나프티리딘-3-카르복실산의 사용 방법
CN101505753B (zh) 2006-06-12 2014-05-21 逊尼希思制药公司 治疗癌症的化合物和组合物
WO2008016678A2 (en) * 2006-08-01 2008-02-07 Sunesis Pharmaceuticals, Inc. Pharmaceutical dosage forms for (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid
ES2556677T3 (es) * 2006-08-02 2016-01-19 Sunesis Pharmaceuticals, Inc. Utilización combinada de ácido (+)-1,4-dihidro-7-[(3S,4S)-3-metoxi-4-(metilamino)-1-pirrolidinil]-4-oxo-1-(2-tiazolil)-1,8-naftiridin-3-carboxílico y citarabina (Ara-C) para el tratamiento de la leucemia
US20090093513A1 (en) * 2007-10-09 2009-04-09 Hamann Mark T Method to Use Compositions Having Antidepressant Anxiolytic and Other Neurological Activity and Compositions of Matter
AU2014277779B2 (en) * 2007-10-22 2016-05-19 Sunesis Pharmaceuticals, Inc. METHODS OF USING (+)-1,4-DIHYDRO-7-[(3s,4s)-3-METHOXY-4-(METHYLAMINO)-1-PYRROLIDINYL]-4-OXO-1-(2-THIAZOLYL)-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACID IN COMBINATION THERAPY
JP6029808B2 (ja) * 2007-10-22 2016-11-24 サネシス ファーマシューティカルズ, インコーポレイテッド 併用療法における(+)−1,4−ジヒドロ−7−[(3s,4s)−3−メトキシ−4−(メチルアミノ)−1−ピロリジニル]−4−オキソ−1−(2−チアゾリル)−1,8−ナフチリジン−3−カルボン酸の使用方法
WO2009075841A2 (en) 2007-12-10 2009-06-18 Sunesis Pharmaceuticals, Inc. Methods of using (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of antecedent hematologic disorders
SG10201504789RA (en) * 2008-12-31 2015-07-30 Sunesis Pharmaceuticals Inc Method Of Preparing (+)-1,4-Dihydro-7-[(3s,4s)-3methoxy-4-(Methylamino)-1-Pyrrolidinyl]-4-Oxo-1-(2-Thiazolyl)-1,8-Naphthyridine-3-Carboxylic Acid
SG10201400258SA (en) * 2009-02-27 2014-05-29 Sunesis Pharmaceuticals Inc Methods Of Using SNS-595 For Treatment Of Cancer Subjects With Reduced BRCA2 Activity
UA110465C2 (en) 2009-09-04 2016-01-12 Sunesis Pharmaceutecals Inc Stable sns-595 composition
US8470817B2 (en) * 2009-10-26 2013-06-25 Sunesis Pharmaceuticals, Inc. Compounds and methods for treatment of cancer
MX354638B (es) 2012-02-27 2018-03-14 Agq Tech Corporate S A Monitoreo y control de las condiciones del suelo.
HRP20181862T1 (hr) 2012-04-24 2019-01-11 Vertex Pharmaceuticals Incorporated Inhibitori dna-pk
PT3527563T (pt) 2013-03-12 2021-12-09 Vertex Pharma Inibidores de adn-pk
WO2014169067A1 (en) * 2013-04-09 2014-10-16 Merrimack Pharmaceuticals, Inc. Compositions for improving outcomes of liposomal chemotherapy
US20160136173A1 (en) * 2013-07-02 2016-05-19 Eustralis Pharmaceuticals Limited (Trading As Pressura Neuro) Method for Preventing and/or Treating Chronic Traumatic Encephalopathy - III
EP3057953B1 (en) 2013-10-17 2018-08-15 Vertex Pharmaceuticals Incorporated Co-crystals of (s)-n-methyl-8-(1-((2'-methyl-[4,5'-bipyrimidin]-6-yl)amino)propan-2-yl)quinoline-4-carboxamide and deuterated derivatives thereof as dna-pk inhibitors
KR101775356B1 (ko) * 2015-07-06 2017-09-06 재단법인 아산사회복지재단 Parp 및 탄키라제 동시 저해제에 대한 감수성 결정 방법
MX394860B (es) 2016-09-27 2025-03-24 Vertex Pharma Metodo para tratar cancer usando una combinacion de agentes que dañan adn e inhibidores de proteina cinasa dependiente de adn (adn-pk).
WO2025033367A1 (ja) * 2023-08-04 2025-02-13 湧永製薬株式会社 抗腫瘍剤併用療法

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3021A (en) * 1843-03-30 Stove with elevated ovejst
US216316A (en) * 1879-06-10 Improvement in latches
US4261989A (en) 1979-02-19 1981-04-14 Kaken Chemical Co. Ltd. Geldanamycin derivatives and antitumor drug
US5078996A (en) * 1985-08-16 1992-01-07 Immunex Corporation Activation of macrophage tumoricidal activity by granulocyte-macrophage colony stimulating factor
PT787726E (pt) 1994-06-14 2002-04-29 Dainippon Pharmaceutical Co Novo composto, processo para a sua producao e agente tumoral
JP4323574B2 (ja) * 1995-12-13 2009-09-02 大日本住友製薬株式会社 抗腫瘍剤
US6753158B1 (en) * 1997-01-13 2004-06-22 Kudos Pharmaceuticals Limited Assays, agents, therapy and diagnosis relating to modulation of cellular DNA repair activity
US20020032216A1 (en) * 1997-03-21 2002-03-14 Lg Chemical Ltd. Salt of naphthyridine carboxylic acid derivative
US6291643B1 (en) 1997-06-05 2001-09-18 Board Of Reports, The University Of Texas System Apaf-1 an activator of caspase-3
US6171857B1 (en) 1997-10-17 2001-01-09 Brown University Research Foundatiion Leucine zipper protein, KARP-1 and methods of regulating DNA dependent protein kinase activity
US5968921A (en) * 1997-10-24 1999-10-19 Orgegon Health Sciences University Compositions and methods for promoting nerve regeneration
IL124015A0 (en) * 1998-04-08 1999-01-26 Yeda Res & Dev Pharmaceutical compositions comprising a protein
JP4294121B2 (ja) 1998-06-05 2009-07-08 大日本住友製薬株式会社 ピリドンカルボン酸誘導体の製造方法およびその中間体
WO2000000644A1 (en) * 1998-06-30 2000-01-06 Sloan-Kettering Institute For Cancer Research Uses of dna-pk
EP1161444A4 (en) 1999-02-26 2005-11-02 Univ Johns Hopkins A novel inhibitor of programmed cell death
US6670144B1 (en) 1999-02-26 2003-12-30 Cyclacel, Ltd. Compositions and methods for monitoring the phosphorylation of natural binding partners
US7163801B2 (en) 1999-09-01 2007-01-16 The Burnham Institute Methods for determining the prognosis for cancer patients using tucan
US6479541B1 (en) * 2000-03-30 2002-11-12 Baxter International Amiodarone-containing parenteral administration
WO2001090404A1 (en) * 2000-05-20 2001-11-29 Cancer Research Technology Limited Drug screening systems and assays
WO2002020500A2 (en) * 2000-09-01 2002-03-14 Icos Corporation Materials and methods to potentiate cancer treatment
AU2001296558A1 (en) * 2000-10-03 2002-04-15 Oncopharmaceutical, Inc. Inhibitors of angiogenesis and tumor growth for local and systemic administration
AU2002228772B2 (en) 2000-11-02 2005-12-08 Sloan Kettering Institute For Cancer Research Methods for enhancing the efficacy of cytotoxic agents through the use of HSP90 inhibitors
US20050158724A1 (en) * 2002-04-05 2005-07-21 Fishel Richard A. Methods, of identifying compounds that modulate a dna repair pathway and/or retroviral infectivity, the compounds, and uses thereof
JP2006523681A (ja) 2003-03-24 2006-10-19 ルイトポルド・ファーマシューティカルズ・インコーポレーテッド Dna−pk阻害剤としてのキサントン、チオキサントンおよびアクリジノン
HUE027266T2 (en) * 2004-03-15 2016-10-28 Sunesis Pharmaceuticals Inc Use of SNS-595 for treating leukemia
US8580814B2 (en) 2006-04-03 2013-11-12 Sunesis Pharmaceuticals, Inc. Methods of using (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4- oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer
KR20080041298A (ko) 2005-09-02 2008-05-09 선에시스 파마슈티컬스 인코포레이티드 암 치료를 위한(+)-1,4-디히드로-7-[(3s,4s)-3-메톡시-4-(메틸아미노)-1-피롤리디닐]-4-옥소-1-(2-티아졸릴)-1,8-나프티리딘-3-카르복실산의 사용 방법
CN101505753B (zh) 2006-06-12 2014-05-21 逊尼希思制药公司 治疗癌症的化合物和组合物
WO2008016678A2 (en) 2006-08-01 2008-02-07 Sunesis Pharmaceuticals, Inc. Pharmaceutical dosage forms for (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid
ES2556677T3 (es) 2006-08-02 2016-01-19 Sunesis Pharmaceuticals, Inc. Utilización combinada de ácido (+)-1,4-dihidro-7-[(3S,4S)-3-metoxi-4-(metilamino)-1-pirrolidinil]-4-oxo-1-(2-tiazolil)-1,8-naftiridin-3-carboxílico y citarabina (Ara-C) para el tratamiento de la leucemia
JP6029808B2 (ja) 2007-10-22 2016-11-24 サネシス ファーマシューティカルズ, インコーポレイテッド 併用療法における(+)−1,4−ジヒドロ−7−[(3s,4s)−3−メトキシ−4−(メチルアミノ)−1−ピロリジニル]−4−オキソ−1−(2−チアゾリル)−1,8−ナフチリジン−3−カルボン酸の使用方法
WO2009075841A2 (en) 2007-12-10 2009-06-18 Sunesis Pharmaceuticals, Inc. Methods of using (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of antecedent hematologic disorders
SG10201504789RA (en) 2008-12-31 2015-07-30 Sunesis Pharmaceuticals Inc Method Of Preparing (+)-1,4-Dihydro-7-[(3s,4s)-3methoxy-4-(Methylamino)-1-Pyrrolidinyl]-4-Oxo-1-(2-Thiazolyl)-1,8-Naphthyridine-3-Carboxylic Acid
SG10201400258SA (en) 2009-02-27 2014-05-29 Sunesis Pharmaceuticals Inc Methods Of Using SNS-595 For Treatment Of Cancer Subjects With Reduced BRCA2 Activity
CN101631081B (zh) 2009-08-12 2011-06-08 华为技术有限公司 一种多级交换网
UA110465C2 (en) * 2009-09-04 2016-01-12 Sunesis Pharmaceutecals Inc Stable sns-595 composition
US8470817B2 (en) 2009-10-26 2013-06-25 Sunesis Pharmaceuticals, Inc. Compounds and methods for treatment of cancer

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