JP2014530819A5 - - Google Patents

Download PDF

Info

Publication number
JP2014530819A5
JP2014530819A5 JP2014535787A JP2014535787A JP2014530819A5 JP 2014530819 A5 JP2014530819 A5 JP 2014530819A5 JP 2014535787 A JP2014535787 A JP 2014535787A JP 2014535787 A JP2014535787 A JP 2014535787A JP 2014530819 A5 JP2014530819 A5 JP 2014530819A5
Authority
JP
Japan
Prior art keywords
genotype
snp
snps
glatiramer acetate
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2014535787A
Other languages
English (en)
Japanese (ja)
Other versions
JP2014530819A (ja
Filing date
Publication date
Application filed filed Critical
Publication of JP2014530819A publication Critical patent/JP2014530819A/ja
Publication of JP2014530819A5 publication Critical patent/JP2014530819A5/ja
Withdrawn legal-status Critical Current

Links

JP2014535787A 2011-10-10 2012-10-09 酢酸グラチラマーに対する臨床的応答性を予測するために有用な一塩基多形 Withdrawn JP2014530819A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201161545282P 2011-10-10 2011-10-10
US61/545,282 2011-10-10
US201261636560P 2012-04-20 2012-04-20
US61/636,560 2012-04-20

Publications (2)

Publication Number Publication Date
JP2014530819A JP2014530819A (ja) 2014-11-20
JP2014530819A5 true JP2014530819A5 (https=) 2015-11-26

Family

ID=48082342

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014535787A Withdrawn JP2014530819A (ja) 2011-10-10 2012-10-09 酢酸グラチラマーに対する臨床的応答性を予測するために有用な一塩基多形

Country Status (17)

Country Link
US (2) US8815511B2 (https=)
EP (1) EP2765857A4 (https=)
JP (1) JP2014530819A (https=)
KR (1) KR20140101730A (https=)
CN (1) CN103957705A (https=)
AR (1) AR088294A1 (https=)
AU (1) AU2012323345A1 (https=)
BR (1) BR112014008752A2 (https=)
CA (1) CA2851510A1 (https=)
EA (1) EA201490749A1 (https=)
HK (1) HK1200274A1 (https=)
IL (1) IL231723A0 (https=)
MX (1) MX2014004309A (https=)
TW (1) TW201326399A (https=)
UY (1) UY34380A (https=)
WO (1) WO2013055683A1 (https=)
ZA (1) ZA201403049B (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2612001T4 (es) 2009-08-20 2018-02-07 Yeda Research & Development Company, Ltd. Terapia de baja frecuencia con acetato de glatirámero
USRE49251E1 (en) 2010-01-04 2022-10-18 Mapi Pharma Ltd. Depot systems comprising glatiramer or pharmacologically acceptable salt thereof
NZ703122A (en) 2010-10-11 2016-06-24 Teva Pharma Cytokine biomarkers as predictive biomarkers of clinical response for glatiramer acetate
KR20140101730A (ko) 2011-10-10 2014-08-20 테바 파마슈티컬 인더스트리즈 리미티드 글라티라머 아세테이트에 대한 임상 반응을 예측하는 데 유용한 단일 뉴클레오티드 다형성
MX2015004563A (es) 2012-10-10 2015-07-14 Teva Pharma Biomarcadores predictivos para respuesta clinica para acetato de glatiramero.
UY35790A (es) * 2013-10-21 2015-05-29 Teva Pharma Marcadores genéticos que predicen la respuesta al acetato de glatiramer
JP6432974B2 (ja) * 2014-06-20 2018-12-05 国立大学法人東北大学 TagSNPの選択方法、選択用コンピュータシステム、及び、選択用ソフトウエア
US9155775B1 (en) 2015-01-28 2015-10-13 Teva Pharmaceutical Industries, Ltd. Process for manufacturing glatiramer acetate product
US20160312284A1 (en) * 2015-04-21 2016-10-27 Teva Pharmaceutical Industries, Ltd. Select single nucleotide polymorphisms predictive of response to glatiramer acetate
US12097292B2 (en) 2016-08-28 2024-09-24 Mapi Pharma Ltd. Process for preparing microparticles containing glatiramer acetate
HUE071047T2 (hu) 2016-08-31 2025-07-28 Mapi Pharma Ltd Glatiramer-acetátot tartalmazó depórendszerek
CN110382052A (zh) 2017-03-26 2019-10-25 Mapi医药公司 用于治疗进展型形式的多发性硬化症的格拉替雷储库系统
US11396825B2 (en) * 2017-08-14 2022-07-26 General Electric Company Turbine diagnostic feature selection system
EP3874455A4 (en) * 2018-11-01 2022-08-03 I2Dx, Inc. INTELLIGENT SYSTEM AND METHOD FOR THERAPY TARGET RECOGNITION
AU2020285475A1 (en) * 2019-05-30 2021-12-23 PolygenRx Pty Ltd A method of treatment or prophylaxis

Family Cites Families (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL36670A (en) 1971-04-21 1974-09-10 Sela M Therapeutic basic copolymers of amino acids
IL113812A (en) 1994-05-24 2000-06-29 Yeda Res & Dev Copolymer-1 pharmaceutical compositions containing it and its use
US6214791B1 (en) 1997-01-10 2001-04-10 Yeda Research And Development Co. Ltd. Treatment of multiple sclerosis through ingestion or inhalation of copolymer-1
IL119989A0 (en) 1997-01-10 1997-04-15 Yeda Res & Dev Pharmaceutical compositions for oral treatment of multiple sclerosis
ES2527760T3 (es) 1998-07-23 2015-01-29 Yeda Research And Development Co., Ltd. Tratamiento de enfermedad de Crohn con copolímero 1 y polipéptidos
JP2003521448A (ja) 1998-07-23 2003-07-15 ザ・プレジデント・アンド・フェローズ・オブ・ハーバード・カレッジ 合成ペプチドおよび自己免疫疾患治療のための使用方法
WO2000005250A1 (en) 1998-07-23 2000-02-03 Yeda Research And Development Co., Ltd Treatment of autoimmune conditions with copolymer 1 and related copolymers and peptides
US6514938B1 (en) 1998-09-25 2003-02-04 Yeda Research And Development Co. Ltd. At The Weizmann Institute Of Science Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use
US6800287B2 (en) 1998-09-25 2004-10-05 Yeda Research And Development Co., Ltd. Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use
SI1115743T1 (sl) 1998-09-25 2010-01-29 Yeda Res And Dev Co Ltd The We Polipeptidi, sorodni kopolimeru 1, za uporabo kot markerji molekulske mase in za terapevtsko uporabo
AU6281599A (en) 1998-10-02 2000-04-26 Yeda Research And Development Co. Ltd. Alternate day administration of copolymer 1 for treating autoimmune diseases
CA2355400A1 (en) 1998-11-12 2000-05-18 Yeda Research And Development Co., Ltd. Pharmaceutical compositions comprising synthetic peptide copolymers and methods for preventing and treating gvhd and hvgd
PT1248643E (pt) 2000-01-20 2005-10-31 Yeda Res & Dev Utilizacao de copolimero 1 e peptidos e polipeptidos congeneres e de celulas t tratadas co estes compostos para terapia neuroprotectora
WO2001060392A1 (en) 2000-02-18 2001-08-23 Yeda Research And Development Co., Ltd. At The Weizmann Institute Of Science Oral, nasal and pulmonary dosage formualtions of copolymer 1
US7022663B2 (en) 2000-02-18 2006-04-04 Yeda Research And Development Co., Ltd. Oral, nasal and pulmonary dosage formulations of copolymer 1
US20020077278A1 (en) 2000-06-05 2002-06-20 Yong V. Wee Use of glatiramer acetate (copolymer 1) in the treatment of central nervous system disorders
CA2411536A1 (en) 2000-06-05 2001-12-13 V. Wee Yong The use of glatiramer acetate (copolymer 1) in the treatment of central nervous system disorders
DK1294390T3 (da) 2000-06-07 2006-04-03 Yeda Res & Dev Anvendelse af copolymer 1 og beslægtede peptider og polypeptider og T-celelr behandlet dermed til neurobeskyttelse mod glutamattoksicitet
WO2002076503A1 (en) 2000-06-20 2002-10-03 Mayo Foundation For Medical Education And Research Treatment of central nervous system diseases by antibodies against glatiramer acetate
SI1459065T1 (sl) 2001-12-04 2010-11-30 Teva Pharma Postopki za merjenje potentnosti glatiramer acetata
IL160105A0 (en) 2001-12-06 2004-06-20 Yeda Res & Dev Vaccine for treatment of motor neurone diseases
US7507531B2 (en) 2002-10-17 2009-03-24 Decode Genetics Chf. Use of 5-lipoxygenase activating protein (FLAP) gene to assess susceptibility for myocardial infarction
US20060019269A1 (en) 2002-10-17 2006-01-26 Decode Genetics, Inc. Susceptibility gene for myocardial infarction, stroke, and PAOD, methods of treatment
US20080293750A1 (en) 2002-10-17 2008-11-27 Anna Helgadottir Susceptibility Gene for Myocardial Infarction, Stroke, Paod and Methods of Treatment
US7851486B2 (en) 2002-10-17 2010-12-14 Decode Genetics Ehf. Susceptibility gene for myocardial infarction, stroke, and PAOD; methods of treatment
WO2004043995A2 (en) 2002-11-13 2004-05-27 Apotex Pharmachem Inc. Process for the preparation of glatiramer acetate by polymerisation of n-carboxy anhydrides of l-alanine, l-tyrosine, benzyl l-glutamate and benzyloxycarbonyl l-lysine
CN102580069B (zh) 2003-01-07 2015-09-30 耶达研究及发展有限公司 用于治疗性免疫接种的含共聚物1的滴眼用疫苗
NZ569331A (en) 2003-01-21 2010-08-27 Yeda Res & Dev COP 1 for treatment of inflammatory bowel diseases
EP1603530A1 (en) 2003-03-04 2005-12-14 Teva Pharmaceutical Industries Limited Combination therapy with glatiramer acetate and alphacalcidol for the treatment of multiple sclerosis
PT1638589E (pt) 2003-05-14 2014-06-12 Teva Pharma Terapia combinada com acetato de glatirâmero e mitoxantrona para o tratamento da esclerose múltipla
US20050064483A1 (en) * 2003-08-28 2005-03-24 Baylor College Of Medicine Gene expression profiling technology for treatment evaluation of multiple sclerosis
CA2540701A1 (en) 2003-09-29 2005-04-07 Chugai Seiyaku Kabushiki Kaisha Proteins expressed in nk cells
US20050170004A1 (en) 2003-10-31 2005-08-04 Vered Rosenberger Nanoparticles for drug delivery
CA2546077C (en) 2003-11-12 2016-07-05 Yeda Research And Development Co. Ltd. Vaccine and method for treatment of neurodegenerative diseases
JP2007538003A (ja) 2004-01-30 2007-12-27 デコード ジェネティクス イーエッチエフ. 心筋梗塞、脳卒中および末梢動脈閉塞疾患に対する感受性遺伝子、治療の方法
US20100216863A1 (en) 2004-01-30 2010-08-26 Decode Genetics Ehf. Susceptibility Gene for Myocardial Infarction, Stroke, and PAOD; Methods of Treatment
WO2005082110A2 (en) * 2004-02-26 2005-09-09 Illumina Inc. Haplotype markers for diagnosing susceptibility to immunological conditions
AU2005218625A1 (en) 2004-03-03 2005-09-15 Teva Pharmaceutical Industries, Ltd. Combination therapy with glatiramer acetate and riluzole
US20050266410A1 (en) 2004-05-19 2005-12-01 Emily Walsh Methods of Human Leukocyte Antigen typing by neighboring single nucleotide polymorphism haplotypes
CA2571035A1 (en) * 2004-06-25 2006-01-12 Id Biomedical Corporation Of Quebec Compositions and methods for treating neurological disorders
US20090048181A1 (en) 2004-09-02 2009-02-19 Schipper Hyman M Combination therapy with glatiramer acetate and n-acetylcysteine for the treatment of multiple sclerosis
US7495072B2 (en) 2004-09-09 2009-02-24 Teva Pharmaceutical Industries, Ltd. Process for preparation of mixtures of polypeptides using purified hydrobromic acid
WO2006029411A2 (en) 2004-09-09 2006-03-16 Yeda Research And Development Co. Ltd. Mixtures of polypeptides, compositions containing and processes for preparing same, and uses thereof
AU2005302500B2 (en) 2004-10-29 2008-11-27 Sandoz Ag Processes for preparing glatiramer
KR20070108388A (ko) 2005-02-02 2007-11-09 테바 파마슈티컬 인더스트리즈 리미티드 가수소분해를 이용한 폴리펩타이드의 혼합물의 제조방법
US20100167983A1 (en) 2007-10-22 2010-07-01 Teva Pharmaceutical Industries, Ltd. Combination therapy with glatiramer acetate and rasagiline for the treatment of multiple sclerosis
PL1848415T3 (pl) 2005-02-17 2013-10-31 Teva Pharma Terapia kombinowana obejmująca octan glatirameru oraz rasagilinę do leczenia stwardnienia rozsianego
WO2006116602A2 (en) 2005-04-25 2006-11-02 Yeda Research And Development Company Markers associated with the therapeutic efficacy of glatiramer acetate
WO2007030573A2 (en) 2005-09-09 2007-03-15 Yeda Research And Development Co. Ltd. Polypeptides useful for molecular weight determinations
WO2007081975A2 (en) 2006-01-11 2007-07-19 Teva Pharmaceutical Industries, Ltd. Method of treating multiple sclerosis
US20080118553A1 (en) 2006-06-12 2008-05-22 Anton Frenkel Tannate salt form of polypeptide mixtures, their preparation and use
WO2008006026A1 (en) 2006-07-05 2008-01-10 Momenta Pharmaceuticals, Inc. Improved process for the preparation of copolymer-1
US20080131887A1 (en) * 2006-11-30 2008-06-05 Stephan Dietrich A Genetic Analysis Systems and Methods
US7795033B2 (en) 2007-03-19 2010-09-14 The United States Of America As Represented By The Department Of Health And Human Services Methods to predict the outcome of treatment with antidepressant medication
US20090149541A1 (en) 2007-11-28 2009-06-11 Yafit Stark Method of delaying the onset of clinically definite multiple sclerosis
US20090177487A1 (en) 2008-01-07 2009-07-09 Tera Eerkes Methods for Assessing Genetic Compatibility
US20110158979A1 (en) 2008-06-13 2011-06-30 Prognomix, Inc. Genetic component of complications in type 2 diabetes
US20100003691A1 (en) 2008-07-04 2010-01-07 Axial Biotech, Inc. Genetic Markers Associated with Degenerative Disc Disease and Uses Thereof
EP2406396A2 (en) * 2009-03-12 2012-01-18 Brainco Biopharma, S.L. A genotyping tool for improving the prognostic and clinical management of ms patients
US20120073585A1 (en) 2009-04-08 2012-03-29 Cedars-Sinai Medical Center Methods of predicting complication and surgery in crohn's disease
RS52367B (sr) 2009-07-15 2012-12-31 Teva Pharmaceutical Industries Ltd. Formulacije glatiramer acetata smanjene zapremine i postupci primene
US8920373B2 (en) 2009-07-15 2014-12-30 Teva Pharmaceutical Industries, Ltd. Reduced volume formulation of glatiramer acetate and methods of administration
ES2612001T4 (es) 2009-08-20 2018-02-07 Yeda Research & Development Company, Ltd. Terapia de baja frecuencia con acetato de glatirámero
US8853378B2 (en) 2009-10-09 2014-10-07 Georgetown University Polynucleotides that home to atherosclerotic plaque
US8759302B2 (en) * 2010-03-16 2014-06-24 Teva Pharmaceutical Industries, Ltd. Methods of treating a subject afflicted with an autoimmune disease using predictive biomarkers of clinical response to glatiramer acetate therapy in multiple sclerosis
NZ703122A (en) 2010-10-11 2016-06-24 Teva Pharma Cytokine biomarkers as predictive biomarkers of clinical response for glatiramer acetate
KR20140101730A (ko) 2011-10-10 2014-08-20 테바 파마슈티컬 인더스트리즈 리미티드 글라티라머 아세테이트에 대한 임상 반응을 예측하는 데 유용한 단일 뉴클레오티드 다형성
MX2015004563A (es) 2012-10-10 2015-07-14 Teva Pharma Biomarcadores predictivos para respuesta clinica para acetato de glatiramero.
JP2016503803A (ja) 2012-12-21 2016-02-08 テバ ファーマシューティカル インダストリーズ リミティド 酢酸グラチラマーの経粘膜送達
CA2895457A1 (en) 2012-12-21 2014-06-26 Teva Pharmaceutical Industries Ltd. Oral transmucosal delivery of glatiramer acetate
JP2016504039A (ja) 2013-01-04 2016-02-12 テバ ファーマシューティカル インダストリーズ リミティド グラチラマーアセテート関連医薬品の特性決定
MX2015012156A (es) 2013-03-12 2015-11-30 Teva Pharma Terapia de induccion de rituximab seguida por terapia de acetato de glatiramer.
UY35790A (es) 2013-10-21 2015-05-29 Teva Pharma Marcadores genéticos que predicen la respuesta al acetato de glatiramer
US9155775B1 (en) 2015-01-28 2015-10-13 Teva Pharmaceutical Industries, Ltd. Process for manufacturing glatiramer acetate product

Similar Documents

Publication Publication Date Title
JP2014530819A5 (https=)
CN102177436B (zh) 鉴定疾病风险因子的方法
JP2022033877A (ja) スタチンの応答および心血管疾患に関連する遺伝子多型、その検出方法ならびに使用
KR101540647B1 (ko) 개인맞춤약물 적용을 위한 한국인 약물유전형 동시다중분석 및 분석 결과를 활용한 약물반응 예측 방법
JP2017512069A5 (https=)
JP2012507297A (ja) Erbb4遺伝子の多型に基づく精神病及び統合失調症の治療法
JP2014530819A (ja) 酢酸グラチラマーに対する臨床的応答性を予測するために有用な一塩基多形
JP2016540729A5 (https=)
CN103789408B (zh) 高血压易感基因组的鉴定
Tang et al. Role of gene polymorphisms/haplotypes and serum levels of interleukin-17A in susceptibility to viral myocarditis
WO2005040416A1 (en) Use of genetic polymorphisms that associate with efficacy of treatment of inflammatory disease
US20130274133A1 (en) Genetic variations in the interleukin-6 receptor gene as predictors of the response of patients to treatment with interleukin-6 receptor inhibitors
JP5899527B2 (ja) 第6染色体短腕21.33領域の一塩基多型に基づく抗てんかん薬による薬疹リスクの検査方法
US20150211065A1 (en) Methods of predicting the development of amd based on chromosome 1 and chromosome 10
CN102808030A (zh) 单核苷多态性rs3888188在检测结核病易感性中的应用
TW202144585A (zh) 治療慢性b型肝炎感染之生物標記及其用途
KR20140096073A (ko) 혈관신생 억제제에 대한 반응성
Ghallab et al. MDR1 gene polymorphism and outcome in Egyptian chronic myeloid leukaemia patients
KR20140064923A (ko) 혈관신생 억제제에 대한 반응성
AU2009273277A1 (en) Use of genetic markers for identifying the response to interferon treatment in Multiple Sclerosis patients
CN104946738B (zh) 内脏脂肪蓄积易感性的判定方法
MX2007011697A (es) Biomarcadores para eficacia de aliskiren como agente hipertensivo.
CN106609302B (zh) 一种辅助诊断线粒体糖尿病的试剂盒
WO2010054806A1 (en) X-chromosomal variation as a diagnostic and therapeutic marker for the progression to aids
US20140314713A1 (en) Methods for determining treatment response in patients infected with hcv genotype 4