CA2851510A1 - Single nucleotide polymorphisms useful to predict clinical response for glatiramer acetate - Google Patents
Single nucleotide polymorphisms useful to predict clinical response for glatiramer acetate Download PDFInfo
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- CA2851510A1 CA2851510A1 CA2851510A CA2851510A CA2851510A1 CA 2851510 A1 CA2851510 A1 CA 2851510A1 CA 2851510 A CA2851510 A CA 2851510A CA 2851510 A CA2851510 A CA 2851510A CA 2851510 A1 CA2851510 A1 CA 2851510A1
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Classifications
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
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- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| US201161545282P | 2011-10-10 | 2011-10-10 | |
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| US201261636560P | 2012-04-20 | 2012-04-20 | |
| US61/636,560 | 2012-04-20 | ||
| PCT/US2012/059352 WO2013055683A1 (en) | 2011-10-10 | 2012-10-09 | Single nucleotide polymorphisms useful to predict clinical response for glatiramer acetate |
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| CA2851510A1 true CA2851510A1 (en) | 2013-04-18 |
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| WO (1) | WO2013055683A1 (https=) |
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| NZ598661A (en) | 2009-08-20 | 2013-02-22 | Yeda Res & Dev | Low frequency glatiramer acetate therapy |
| USRE49251E1 (en) | 2010-01-04 | 2022-10-18 | Mapi Pharma Ltd. | Depot systems comprising glatiramer or pharmacologically acceptable salt thereof |
| CA2814500A1 (en) | 2010-10-11 | 2012-04-19 | Teva Pharmaceutical Industries Ltd | Cytokine biomarkers as predictive biomarkers of clinical response for glatiramer acetate |
| HK1200274A1 (en) | 2011-10-10 | 2015-08-07 | Teva Pharmaceutical Industries Ltd. | Single nucleotide polymorphisms useful to predict clinical response for glatiramer acetate |
| HK1213830A1 (zh) * | 2012-10-10 | 2016-07-15 | Teva Pharmaceutical Industries Ltd. | 用於预测醋酸格拉替雷临床反应的生物标志物 |
| UY35790A (es) * | 2013-10-21 | 2015-05-29 | Teva Pharma | Marcadores genéticos que predicen la respuesta al acetato de glatiramer |
| JP6432974B2 (ja) * | 2014-06-20 | 2018-12-05 | 国立大学法人東北大学 | ＴａｇＳＮＰの選択方法、選択用コンピュータシステム、及び、選択用ソフトウエア |
| US9155775B1 (en) | 2015-01-28 | 2015-10-13 | Teva Pharmaceutical Industries, Ltd. | Process for manufacturing glatiramer acetate product |
| WO2016172124A1 (en) * | 2015-04-21 | 2016-10-27 | Teva Pharmaceutical Industries Ltd. | Select single nucleotide polymorphisms predictive of response to glatiramer acetate |
| US12097292B2 (en) | 2016-08-28 | 2024-09-24 | Mapi Pharma Ltd. | Process for preparing microparticles containing glatiramer acetate |
| CN109982712A (zh) | 2016-08-31 | 2019-07-05 | Mapi医药公司 | 包含醋酸格拉替雷的储库系统 |
| CN110382052A (zh) | 2017-03-26 | 2019-10-25 | Mapi医药公司 | 用于治疗进展型形式的多发性硬化症的格拉替雷储库系统 |
| US11396825B2 (en) * | 2017-08-14 | 2022-07-26 | General Electric Company | Turbine diagnostic feature selection system |
| WO2020092753A1 (en) * | 2018-11-01 | 2020-05-07 | I2Dx, Inc. | Intelligent system and methods for therapeutic target identification |
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| IL113812A (en) | 1994-05-24 | 2000-06-29 | Yeda Res & Dev | Copolymer-1 pharmaceutical compositions containing it and its use |
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| IL119989A0 (en) | 1997-01-10 | 1997-04-15 | Yeda Res & Dev | Pharmaceutical compositions for oral treatment of multiple sclerosis |
| ES2527760T3 (es) | 1998-07-23 | 2015-01-29 | Yeda Research And Development Co., Ltd. | Tratamiento de enfermedad de Crohn con copolímero 1 y polipéptidos |
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| WO2000005249A2 (en) | 1998-07-23 | 2000-02-03 | The President And Fellows Of Harvard College | Synthetic peptides and methods of use for autoimmune disease therapies |
| US6514938B1 (en) | 1998-09-25 | 2003-02-04 | Yeda Research And Development Co. Ltd. At The Weizmann Institute Of Science | Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use |
| DK2239269T3 (da) | 1998-09-25 | 2013-04-29 | Yeda Res & Dev | Anvendelse af peptider afledt af copolymer-1 som molekylvægtsmarkører |
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| WO2000020010A1 (en) | 1998-10-02 | 2000-04-13 | Yeda Research And Development Co., Ltd. | Alternate day administration of copolymer 1 for treating autoimmune diseases |
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| HK1200274A1 (en) | 2011-10-10 | 2015-08-07 | Teva Pharmaceutical Industries Ltd. | Single nucleotide polymorphisms useful to predict clinical response for glatiramer acetate |
| HK1213830A1 (zh) | 2012-10-10 | 2016-07-15 | Teva Pharmaceutical Industries Ltd. | 用於预测醋酸格拉替雷临床反应的生物标志物 |
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2012
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- 2012-10-09 JP JP2014535787A patent/JP2014530819A/ja not_active Withdrawn
- 2012-10-09 KR KR1020147012550A patent/KR20140101730A/ko not_active Withdrawn
- 2012-10-09 AU AU2012323345A patent/AU2012323345A1/en not_active Abandoned
- 2012-10-09 CA CA2851510A patent/CA2851510A1/en not_active Abandoned
- 2012-10-09 CN CN201280058097.0A patent/CN103957705A/zh active Pending
- 2012-10-09 MX MX2014004309A patent/MX2014004309A/es unknown
- 2012-10-09 WO PCT/US2012/059352 patent/WO2013055683A1/en not_active Ceased
- 2012-10-09 TW TW101137349A patent/TW201326399A/zh unknown
- 2012-10-09 EA EA201490749A patent/EA201490749A1/ru unknown
- 2012-10-09 US US13/648,135 patent/US8815511B2/en not_active Expired - Fee Related
- 2012-10-09 EP EP12840243.5A patent/EP2765857A4/en not_active Withdrawn
- 2012-10-09 BR BR112014008752A patent/BR112014008752A2/pt not_active IP Right Cessation
- 2012-10-10 UY UY0001034380A patent/UY34380A/es not_active Application Discontinuation
- 2012-10-10 AR ARP120103778A patent/AR088294A1/es unknown
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2014
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- 2014-04-25 ZA ZA2014/03049A patent/ZA201403049B/en unknown
- 2014-08-25 US US14/467,954 patent/US9499868B2/en not_active Expired - Fee Related
Also Published As
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| JP2014530819A (ja) | 2014-11-20 |
| US9499868B2 (en) | 2016-11-22 |
| CN103957705A (zh) | 2014-07-30 |
| IL231723A0 (en) | 2014-05-28 |
| WO2013055683A1 (en) | 2013-04-18 |
| MX2014004309A (es) | 2015-07-06 |
| EA201490749A1 (ru) | 2014-09-30 |
| TW201326399A (zh) | 2013-07-01 |
| KR20140101730A (ko) | 2014-08-20 |
| AU2012323345A1 (en) | 2014-05-22 |
| HK1200274A1 (en) | 2015-08-07 |
| US20150045306A1 (en) | 2015-02-12 |
| ZA201403049B (en) | 2015-09-30 |
| UY34380A (es) | 2013-05-31 |
| EP2765857A1 (en) | 2014-08-20 |
| EP2765857A4 (en) | 2015-12-09 |
| US20130123189A1 (en) | 2013-05-16 |
| AR088294A1 (es) | 2014-05-21 |
| NZ624258A (en) | 2016-09-30 |
| BR112014008752A2 (pt) | 2017-04-25 |
| US8815511B2 (en) | 2014-08-26 |
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