CA2851510A1 - Single nucleotide polymorphisms useful to predict clinical response for glatiramer acetate - Google Patents

Single nucleotide polymorphisms useful to predict clinical response for glatiramer acetate Download PDF

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Publication number
CA2851510A1
CA2851510A1 CA2851510A CA2851510A CA2851510A1 CA 2851510 A1 CA2851510 A1 CA 2851510A1 CA 2851510 A CA2851510 A CA 2851510A CA 2851510 A CA2851510 A CA 2851510A CA 2851510 A1 CA2851510 A1 CA 2851510A1
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CA
Canada
Prior art keywords
snps
genotype
kit
glatiramer acetate
broad
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2851510A
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English (en)
French (fr)
Inventor
Amir TCHELET
Fabio Macciardi
Joseph Levy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teva Pharmaceutical Industries Ltd
Original Assignee
Teva Pharmaceutical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharmaceutical Industries Ltd filed Critical Teva Pharmaceutical Industries Ltd
Publication of CA2851510A1 publication Critical patent/CA2851510A1/en
Abandoned legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/02Peptides of undefined number of amino acids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CA2851510A 2011-10-10 2012-10-09 Single nucleotide polymorphisms useful to predict clinical response for glatiramer acetate Abandoned CA2851510A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161545282P 2011-10-10 2011-10-10
US61/545,282 2011-10-10
US201261636560P 2012-04-20 2012-04-20
US61/636,560 2012-04-20
PCT/US2012/059352 WO2013055683A1 (en) 2011-10-10 2012-10-09 Single nucleotide polymorphisms useful to predict clinical response for glatiramer acetate

Publications (1)

Publication Number Publication Date
CA2851510A1 true CA2851510A1 (en) 2013-04-18

Family

ID=48082342

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2851510A Abandoned CA2851510A1 (en) 2011-10-10 2012-10-09 Single nucleotide polymorphisms useful to predict clinical response for glatiramer acetate

Country Status (17)

Country Link
US (2) US8815511B2 (https=)
EP (1) EP2765857A4 (https=)
JP (1) JP2014530819A (https=)
KR (1) KR20140101730A (https=)
CN (1) CN103957705A (https=)
AR (1) AR088294A1 (https=)
AU (1) AU2012323345A1 (https=)
BR (1) BR112014008752A2 (https=)
CA (1) CA2851510A1 (https=)
EA (1) EA201490749A1 (https=)
HK (1) HK1200274A1 (https=)
IL (1) IL231723A0 (https=)
MX (1) MX2014004309A (https=)
TW (1) TW201326399A (https=)
UY (1) UY34380A (https=)
WO (1) WO2013055683A1 (https=)
ZA (1) ZA201403049B (https=)

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US12097292B2 (en) 2016-08-28 2024-09-24 Mapi Pharma Ltd. Process for preparing microparticles containing glatiramer acetate
HUE071047T2 (hu) 2016-08-31 2025-07-28 Mapi Pharma Ltd Glatiramer-acetátot tartalmazó depórendszerek
CN110382052A (zh) 2017-03-26 2019-10-25 Mapi医药公司 用于治疗进展型形式的多发性硬化症的格拉替雷储库系统
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Also Published As

Publication number Publication date
NZ624258A (en) 2016-09-30
JP2014530819A (ja) 2014-11-20
WO2013055683A1 (en) 2013-04-18
UY34380A (es) 2013-05-31
US20150045306A1 (en) 2015-02-12
AR088294A1 (es) 2014-05-21
EA201490749A1 (ru) 2014-09-30
BR112014008752A2 (pt) 2017-04-25
CN103957705A (zh) 2014-07-30
IL231723A0 (en) 2014-05-28
MX2014004309A (es) 2015-07-06
US9499868B2 (en) 2016-11-22
EP2765857A1 (en) 2014-08-20
AU2012323345A1 (en) 2014-05-22
HK1200274A1 (en) 2015-08-07
US8815511B2 (en) 2014-08-26
ZA201403049B (en) 2015-09-30
EP2765857A4 (en) 2015-12-09
KR20140101730A (ko) 2014-08-20
US20130123189A1 (en) 2013-05-16
TW201326399A (zh) 2013-07-01

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Legal Events

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EEER Examination request

Effective date: 20170912

FZDE Discontinued

Effective date: 20191009