JP2014530819A5 - - Google Patents

Download PDF

Info

Publication number
JP2014530819A5
JP2014530819A5 JP2014535787A JP2014535787A JP2014530819A5 JP 2014530819 A5 JP2014530819 A5 JP 2014530819A5 JP 2014535787 A JP2014535787 A JP 2014535787A JP 2014535787 A JP2014535787 A JP 2014535787A JP 2014530819 A5 JP2014530819 A5 JP 2014530819A5
Authority
JP
Japan
Prior art keywords
genotype
snp
snps
glatiramer acetate
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2014535787A
Other languages
English (en)
Japanese (ja)
Other versions
JP2014530819A (ja
Filing date
Publication date
Application filed filed Critical
Publication of JP2014530819A publication Critical patent/JP2014530819A/ja
Publication of JP2014530819A5 publication Critical patent/JP2014530819A5/ja
Withdrawn legal-status Critical Current

Links

JP2014535787A 2011-10-10 2012-10-09 酢酸グラチラマーに対する臨床的応答性を予測するために有用な一塩基多形 Withdrawn JP2014530819A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201161545282P 2011-10-10 2011-10-10
US61/545,282 2011-10-10
US201261636560P 2012-04-20 2012-04-20
US61/636,560 2012-04-20

Publications (2)

Publication Number Publication Date
JP2014530819A JP2014530819A (ja) 2014-11-20
JP2014530819A5 true JP2014530819A5 (cg-RX-API-DMAC7.html) 2015-11-26

Family

ID=48082342

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014535787A Withdrawn JP2014530819A (ja) 2011-10-10 2012-10-09 酢酸グラチラマーに対する臨床的応答性を予測するために有用な一塩基多形

Country Status (17)

Country Link
US (2) US8815511B2 (cg-RX-API-DMAC7.html)
EP (1) EP2765857A4 (cg-RX-API-DMAC7.html)
JP (1) JP2014530819A (cg-RX-API-DMAC7.html)
KR (1) KR20140101730A (cg-RX-API-DMAC7.html)
CN (1) CN103957705A (cg-RX-API-DMAC7.html)
AR (1) AR088294A1 (cg-RX-API-DMAC7.html)
AU (1) AU2012323345A1 (cg-RX-API-DMAC7.html)
BR (1) BR112014008752A2 (cg-RX-API-DMAC7.html)
CA (1) CA2851510A1 (cg-RX-API-DMAC7.html)
EA (1) EA201490749A1 (cg-RX-API-DMAC7.html)
HK (1) HK1200274A1 (cg-RX-API-DMAC7.html)
IL (1) IL231723A0 (cg-RX-API-DMAC7.html)
MX (1) MX2014004309A (cg-RX-API-DMAC7.html)
TW (1) TW201326399A (cg-RX-API-DMAC7.html)
UY (1) UY34380A (cg-RX-API-DMAC7.html)
WO (1) WO2013055683A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201403049B (cg-RX-API-DMAC7.html)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE031282T2 (hu) 2009-08-20 2017-06-28 Yeda Res & Dev Alacsony gyakoriságú glatiramer acetát terápia
USRE49251E1 (en) 2010-01-04 2022-10-18 Mapi Pharma Ltd. Depot systems comprising glatiramer or pharmacologically acceptable salt thereof
NZ703122A (en) 2010-10-11 2016-06-24 Teva Pharma Cytokine biomarkers as predictive biomarkers of clinical response for glatiramer acetate
KR20140101730A (ko) 2011-10-10 2014-08-20 테바 파마슈티컬 인더스트리즈 리미티드 글라티라머 아세테이트에 대한 임상 반응을 예측하는 데 유용한 단일 뉴클레오티드 다형성
HK1213830A1 (zh) 2012-10-10 2016-07-15 Teva Pharmaceutical Industries Ltd. 用於预测醋酸格拉替雷临床反应的生物标志物
UY35790A (es) 2013-10-21 2015-05-29 Teva Pharma Marcadores genéticos que predicen la respuesta al acetato de glatiramer
JP6432974B2 (ja) * 2014-06-20 2018-12-05 国立大学法人東北大学 ＴａｇＳＮＰの選択方法、選択用コンピュータシステム、及び、選択用ソフトウエア
US9155775B1 (en) 2015-01-28 2015-10-13 Teva Pharmaceutical Industries, Ltd. Process for manufacturing glatiramer acetate product
US20160312284A1 (en) * 2015-04-21 2016-10-27 Teva Pharmaceutical Industries, Ltd. Select single nucleotide polymorphisms predictive of response to glatiramer acetate
US12097292B2 (en) 2016-08-28 2024-09-24 Mapi Pharma Ltd. Process for preparing microparticles containing glatiramer acetate
DK3506921T3 (da) 2016-08-31 2023-07-31 Mapi Pharma Ltd Depotsystemer, der omfatter glatirameracetat
US11167003B2 (en) 2017-03-26 2021-11-09 Mapi Pharma Ltd. Methods for suppressing or alleviating primary or secondary progressive multiple sclerosis (PPMS or SPMS) using sustained release glatiramer depot systems
US11396825B2 (en) * 2017-08-14 2022-07-26 General Electric Company Turbine diagnostic feature selection system
US20220005548A1 (en) * 2018-11-01 2022-01-06 I2Dx, Inc. Intelligent system and methods for therapeutic target identification
US20220172811A1 (en) * 2019-05-30 2022-06-02 The University Of Newcastle A method of treatment or prophylaxis

Family Cites Families (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL36670A (en) 1971-04-21 1974-09-10 Sela M Therapeutic basic copolymers of amino acids
IL113812A (en) 1994-05-24 2000-06-29 Yeda Res & Dev Copolymer-1 pharmaceutical compositions containing it and its use
IL119989A0 (en) 1997-01-10 1997-04-15 Yeda Res & Dev Pharmaceutical compositions for oral treatment of multiple sclerosis
US6214791B1 (en) 1997-01-10 2001-04-10 Yeda Research And Development Co. Ltd. Treatment of multiple sclerosis through ingestion or inhalation of copolymer-1
IL140592A0 (en) 1998-07-23 2002-02-10 Harvard College Synthetic peptides and methods of use for autoimmune disease therapies
WO2000005250A1 (en) 1998-07-23 2000-02-03 Yeda Research And Development Co., Ltd Treatment of autoimmune conditions with copolymer 1 and related copolymers and peptides
ES2527760T3 (es) 1998-07-23 2015-01-29 Yeda Research And Development Co., Ltd. Tratamiento de enfermedad de Crohn con copolímero 1 y polipéptidos
US6800287B2 (en) 1998-09-25 2004-10-05 Yeda Research And Development Co., Ltd. Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use
EP2090583B1 (en) 1998-09-25 2011-07-13 Yeda Research And Development Co., Ltd. Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use
US6514938B1 (en) 1998-09-25 2003-02-04 Yeda Research And Development Co. Ltd. At The Weizmann Institute Of Science Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use
WO2000020010A1 (en) 1998-10-02 2000-04-13 Yeda Research And Development Co., Ltd. Alternate day administration of copolymer 1 for treating autoimmune diseases
EP1128839A4 (en) 1998-11-12 2002-10-09 Yeda Res & Dev PHARMACEUTICAL COMPOSITIONS CONTAINING COPOLYMERS OF SYNTHETIC PEPTIDES AND METHODS FOR PREVENTING AND TREATING GVHD AND HVGD
HK1054507B (zh) 2000-01-20 2008-10-31 耶达研究及发展有限公司 共聚物1和相关肽和多肽及其处理过的t细胞在神经保护性治疗中的用途
ATE329608T1 (de) 2000-02-18 2006-07-15 Yeda Res & Dev Formulierungen von copolymer 1 (glatirameracetat) zur oralen, nasalen und pulmonalen verabreichung
ZA200206457B (en) 2000-02-18 2003-08-13 Yeda Res & Dev Oral, nasal and pulmonary dosage formulations of copolymer 1.
JP2003535118A (ja) 2000-06-05 2003-11-25 テバ ファーマシューティカル インダストリーズ リミティド 中枢神経系障害の治療におけるグラチラマーアセテート（共重合体１）の使用
US20020077278A1 (en) 2000-06-05 2002-06-20 Yong V. Wee Use of glatiramer acetate (copolymer 1) in the treatment of central nervous system disorders
EP1294390B1 (en) 2000-06-07 2006-01-04 YEDA RESEARCH AND DEVELOPMENT CO., Ltd. The use of copolymer 1 and related peptides and polypeptides and t cells treated therewith for neuroprotection from glutamate toxicity
WO2002076503A1 (en) 2000-06-20 2002-10-03 Mayo Foundation For Medical Education And Research Treatment of central nervous system diseases by antibodies against glatiramer acetate
MXPA04005433A (es) 2001-12-04 2004-10-11 Teva Pharma Proceso para la medicion de la potencia de acetato de glatiramero.
CN102151330B (zh) 2001-12-06 2017-04-12 耶达研究及发展有限公司 治疗运动神经元疾病的疫苗和方法
US20080293750A1 (en) 2002-10-17 2008-11-27 Anna Helgadottir Susceptibility Gene for Myocardial Infarction, Stroke, Paod and Methods of Treatment
US20060019269A1 (en) 2002-10-17 2006-01-26 Decode Genetics, Inc. Susceptibility gene for myocardial infarction, stroke, and PAOD, methods of treatment
US7507531B2 (en) 2002-10-17 2009-03-24 Decode Genetics Chf. Use of 5-lipoxygenase activating protein (FLAP) gene to assess susceptibility for myocardial infarction
US7851486B2 (en) 2002-10-17 2010-12-14 Decode Genetics Ehf. Susceptibility gene for myocardial infarction, stroke, and PAOD; methods of treatment
AU2003283152A1 (en) 2002-11-13 2004-06-03 Apotex Pharmachem Inc. Process for the preparation of glatiramer acetate by polymerisation of n-carboxy anhydrides of l-alanine, l-tyrosine, benzyl l-glutamate and benzyloxycarbonyl l-lysine
EP1583506B1 (en) 2003-01-07 2012-03-07 Yeda Research And Development Co., Ltd. Eye-drop vaccine containing copolymer 1 for therapeutic immunization
PT1592384E (pt) 2003-01-21 2013-01-28 Yeda Res & Dev Cop-1 para o tratamento de doenças inflamatórias do intestino
CA2518079A1 (en) 2003-03-04 2004-10-28 Teva Pharmaceutical Industries, Ltd. Combination therapy with glatiramer acetate and alphacalcidol for the treatment of multiple sclerosis
HRP20140524T1 (hr) 2003-05-14 2014-12-19 Teva Pharmaceutical Industries Ltd. Kombinacijska terapija glatiramer acetatom i mitoksantronom za lijeäśenje multiple skleroze
US20050064483A1 (en) 2003-08-28 2005-03-24 Baylor College Of Medicine Gene expression profiling technology for treatment evaluation of multiple sclerosis
AU2004276646B2 (en) 2003-09-29 2012-07-12 Chugai Seiyaku Kabushiki Kaisha Protein expressed in NK cell
EA200600877A1 (ru) 2003-10-31 2006-12-29 Тева Фармасьютикал Индастриз, Лтд. Наночастицы для доставки лекарств
CA2546077C (en) 2003-11-12 2016-07-05 Yeda Research And Development Co. Ltd. Vaccine and method for treatment of neurodegenerative diseases
CA2553928A1 (en) 2004-01-30 2005-08-18 Decode Genetics Ehf. Susceptibility gene for myocardial infarction, stroke, and paod; methods of treatment
US20100216863A1 (en) 2004-01-30 2010-08-26 Decode Genetics Ehf. Susceptibility Gene for Myocardial Infarction, Stroke, and PAOD; Methods of Treatment
WO2005082110A2 (en) * 2004-02-26 2005-09-09 Illumina Inc. Haplotype markers for diagnosing susceptibility to immunological conditions
CA2558380A1 (en) 2004-03-03 2005-09-15 Teva Pharmaceutical Industries, Ltd. Combination therapy with glatiramer acetate and riluzole
US20050266410A1 (en) 2004-05-19 2005-12-01 Emily Walsh Methods of Human Leukocyte Antigen typing by neighboring single nucleotide polymorphism haplotypes
WO2006004749A2 (en) 2004-06-25 2006-01-12 Id Biomedical Corporation Of Quebec Compositions and methods for treating neurological disorders
CA2579038A1 (en) 2004-09-02 2006-03-16 Teva Pharmaceutical Industries, Ltd. Combination therapy with glatiramer acetate and n-acetylcysteine for the treatment of multiple sclerosis
KR101317131B1 (ko) 2004-09-09 2013-10-10 테바 파마슈티컬 인더스트리즈 리미티드 정제된 브롬화 수소산을 이용한 폴리펩타이드류의 혼합물의제조방법
HRP20160455T1 (hr) 2004-09-09 2016-07-15 Yeda Research And Development Co., Ltd. Smjese polipeptida, sastavi koji ih sadrže i postupci za njihovu pripremu, te njihove primjene
WO2006050122A1 (en) 2004-10-29 2006-05-11 Sandoz Ag Processes for preparing glatiramer
WO2006083608A1 (en) 2005-02-02 2006-08-10 Teva Pharmaceutical Industries, Ltd. Process for producing polypeptide mixtures using hydrogenolysis
US20080261894A1 (en) 2005-02-17 2008-10-23 Rivka Kreitman Combination Therapy with Glatiramer Acetate and Rasagiline for the Treatment of Multiple Sclerosis
US20100167983A1 (en) 2007-10-22 2010-07-01 Teva Pharmaceutical Industries, Ltd. Combination therapy with glatiramer acetate and rasagiline for the treatment of multiple sclerosis
CA2606194A1 (en) 2005-04-25 2006-11-02 Yeda Research And Development Company Markers associated with the therapeutic efficacy of glatiramer acetate
WO2007030573A2 (en) 2005-09-09 2007-03-15 Yeda Research And Development Co. Ltd. Polypeptides useful for molecular weight determinations
WO2007081975A2 (en) 2006-01-11 2007-07-19 Teva Pharmaceutical Industries, Ltd. Method of treating multiple sclerosis
US20080118553A1 (en) 2006-06-12 2008-05-22 Anton Frenkel Tannate salt form of polypeptide mixtures, their preparation and use
ATE452140T1 (de) 2006-07-05 2010-01-15 Momenta Pharmaceuticals Inc Verbessertes verfahren zur herstellung von copolymer-1
US20080131887A1 (en) * 2006-11-30 2008-06-05 Stephan Dietrich A Genetic Analysis Systems and Methods
US7795033B2 (en) 2007-03-19 2010-09-14 The United States Of America As Represented By The Department Of Health And Human Services Methods to predict the outcome of treatment with antidepressant medication
US20090149541A1 (en) 2007-11-28 2009-06-11 Yafit Stark Method of delaying the onset of clinically definite multiple sclerosis
US20090177487A1 (en) 2008-01-07 2009-07-09 Tera Eerkes Methods for Assessing Genetic Compatibility
US20100136540A1 (en) 2008-06-13 2010-06-03 Pavel Hamet Methods and compositions for characterizing patients for clinical outcome trials
EP2310533A4 (en) 2008-07-04 2012-03-14 Axial Biotech Inc GENETIC MARKERS ASSOCIATED WITH DEGENERATIVE DISC DISEASE AND USES THEREOF
EP2406396A2 (en) * 2009-03-12 2012-01-18 Brainco Biopharma, S.L. A genotyping tool for improving the prognostic and clinical management of ms patients
WO2010118210A1 (en) 2009-04-08 2010-10-14 Cedars-Sinai Medical Center Methods of predicting complication and surgery in crohn's disease
US8920373B2 (en) 2009-07-15 2014-12-30 Teva Pharmaceutical Industries, Ltd. Reduced volume formulation of glatiramer acetate and methods of administration
CA2697570C (en) 2009-07-15 2011-11-01 Teva Pharmaceutical Industries, Ltd. Reduced volume formulation of glatiramer acetate and methods of administration
HUE031282T2 (hu) 2009-08-20 2017-06-28 Yeda Res & Dev Alacsony gyakoriságú glatiramer acetát terápia
US8853378B2 (en) 2009-10-09 2014-10-07 Georgetown University Polynucleotides that home to atherosclerotic plaque
US8759302B2 (en) 2010-03-16 2014-06-24 Teva Pharmaceutical Industries, Ltd. Methods of treating a subject afflicted with an autoimmune disease using predictive biomarkers of clinical response to glatiramer acetate therapy in multiple sclerosis
NZ703122A (en) 2010-10-11 2016-06-24 Teva Pharma Cytokine biomarkers as predictive biomarkers of clinical response for glatiramer acetate
KR20140101730A (ko) 2011-10-10 2014-08-20 테바 파마슈티컬 인더스트리즈 리미티드 글라티라머 아세테이트에 대한 임상 반응을 예측하는 데 유용한 단일 뉴클레오티드 다형성
HK1213830A1 (zh) 2012-10-10 2016-07-15 Teva Pharmaceutical Industries Ltd. 用於预测醋酸格拉替雷临床反应的生物标志物
KR20150111919A (ko) 2012-12-21 2015-10-06 테바 파마슈티컬 인더스트리즈 리미티드 글라티라머 아세테이트의 경구 경점막 전달
JP2016503803A (ja) 2012-12-21 2016-02-08 テバ ファーマシューティカル インダストリーズ リミティド 酢酸グラチラマーの経粘膜送達
EA201591251A1 (ru) 2013-01-04 2016-05-31 Тева Фармасьютикал Индастриз Лтд. Характеризация лекарственного продукта, родственного ацетату глатирамера
EA201591687A1 (ru) 2013-03-12 2016-07-29 Тева Фармасьютикал Индастриз Лтд. Индукционная терапия ритуксимабом с последующим лечением с использованием глатирамера ацетата
UY35790A (es) 2013-10-21 2015-05-29 Teva Pharma Marcadores genéticos que predicen la respuesta al acetato de glatiramer
US9155775B1 (en) 2015-01-28 2015-10-13 Teva Pharmaceutical Industries, Ltd. Process for manufacturing glatiramer acetate product

Similar Documents

Publication Publication Date Title
JP2014530819A5 (cg-RX-API-DMAC7.html)
CN102177436B (zh) 鉴定疾病风险因子的方法
JP2022033877A (ja) スタチンの応答および心血管疾患に関連する遺伝子多型、その検出方法ならびに使用
KR101540647B1 (ko) 개인맞춤약물 적용을 위한 한국인 약물유전형 동시다중분석 및 분석 결과를 활용한 약물반응 예측 방법
JP2017512069A5 (cg-RX-API-DMAC7.html)
JP2012507297A (ja) Ｅｒｂｂ４遺伝子の多型に基づく精神病及び統合失調症の治療法
JP2014530819A (ja) 酢酸グラチラマーに対する臨床的応答性を予測するために有用な一塩基多形
JP2016540729A5 (cg-RX-API-DMAC7.html)
CN103865997B (zh) 高血压易感基因组的鉴定
Tang et al. Role of gene polymorphisms/haplotypes and serum levels of interleukin-17A in susceptibility to viral myocarditis
US20210180129A1 (en) Methods of predicting the development of amd based on chromosome 1 and chromosome10
WO2005040416A1 (en) Use of genetic polymorphisms that associate with efficacy of treatment of inflammatory disease
US20130274133A1 (en) Genetic variations in the interleukin-6 receptor gene as predictors of the response of patients to treatment with interleukin-6 receptor inhibitors
JP5899527B2 (ja) 第６染色体短腕２１．３３領域の一塩基多型に基づく抗てんかん薬による薬疹リスクの検査方法
CN102808030B (zh) 单核苷多态性rs3888188在检测结核病易感性中的应用
TW202144585A (zh) 治療慢性b型肝炎感染之生物標記及其用途
KR20140096073A (ko) 혈관신생 억제제에 대한 반응성
Ghallab et al. MDR1 gene polymorphism and outcome in Egyptian chronic myeloid leukaemia patients
KR20140064923A (ko) 혈관신생 억제제에 대한 반응성
CN104946738B (zh) 内脏脂肪蓄积易感性的判定方法
MX2007011697A (es) Biomarcadores para eficacia de aliskiren como agente hipertensivo.
EP2186907A1 (en) X-chromosomal variation as a diagnostic and therapeutic marker for the progression to AIDS
CN106609302B (zh) 一种辅助诊断线粒体糖尿病的试剂盒
US20140314713A1 (en) Methods for determining treatment response in patients infected with hcv genotype 4
Lee ChangMin et al. Polymorphism in the serotonin transporter protein gene in Maltese dogs with degenerative mitral valve disease.