JP2017512069A5 - - Google Patents
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- JP2017512069A5 JP2017512069A5 JP2016570925A JP2016570925A JP2017512069A5 JP 2017512069 A5 JP2017512069 A5 JP 2017512069A5 JP 2016570925 A JP2016570925 A JP 2016570925A JP 2016570925 A JP2016570925 A JP 2016570925A JP 2017512069 A5 JP2017512069 A5 JP 2017512069A5
- Authority
- JP
- Japan
- Prior art keywords
- risk
- patient
- low
- abcc3
- genotype
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 238000000034 method Methods 0.000 claims 29
- 102100028162 ATP-binding cassette sub-family C member 3 Human genes 0.000 claims 21
- 101000986633 Homo sapiens ATP-binding cassette sub-family C member 3 Proteins 0.000 claims 21
- 208000031649 Postoperative Nausea and Vomiting Diseases 0.000 claims 16
- 230000035772 mutation Effects 0.000 claims 16
- 208000004756 Respiratory Insufficiency Diseases 0.000 claims 15
- 206010038678 Respiratory depression Diseases 0.000 claims 15
- 230000002411 adverse Effects 0.000 claims 14
- 230000007614 genetic variation Effects 0.000 claims 13
- 239000003795 chemical substances by application Substances 0.000 claims 10
- BQJCRHHNABKAKU-KBQPJGBKSA-N morphine Chemical compound O([C@H]1[C@H](C=C[C@H]23)O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O BQJCRHHNABKAKU-KBQPJGBKSA-N 0.000 claims 10
- 102100029111 Fatty-acid amide hydrolase 1 Human genes 0.000 claims 6
- 101000937693 Homo sapiens Fatty acid 2-hydroxylase Proteins 0.000 claims 6
- 101000918494 Homo sapiens Fatty-acid amide hydrolase 1 Proteins 0.000 claims 6
- 239000003814 drug Substances 0.000 claims 5
- 229960005181 morphine Drugs 0.000 claims 5
- 101710163270 Nuclease Proteins 0.000 claims 4
- 230000002035 prolonged effect Effects 0.000 claims 4
- 238000011084 recovery Methods 0.000 claims 4
- 108700028369 Alleles Proteins 0.000 claims 3
- 239000003298 DNA probe Substances 0.000 claims 3
- 102000016928 DNA-directed DNA polymerase Human genes 0.000 claims 3
- 108010014303 DNA-directed DNA polymerase Proteins 0.000 claims 3
- 230000000694 effects Effects 0.000 claims 3
- 230000002068 genetic effect Effects 0.000 claims 3
- 230000036592 analgesia Effects 0.000 claims 2
- 230000000202 analgesic effect Effects 0.000 claims 2
- 239000000730 antalgic agent Substances 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 238000003205 genotyping method Methods 0.000 claims 2
- 239000000523 sample Substances 0.000 claims 2
- 229940035676 analgesics Drugs 0.000 claims 1
- 238000003556 assay Methods 0.000 claims 1
- 238000004166 bioassay Methods 0.000 claims 1
- 239000012472 biological sample Substances 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 238000003745 diagnosis Methods 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
- 229940121367 non-opioid analgesics Drugs 0.000 claims 1
- 239000000014 opioid analgesic Substances 0.000 claims 1
- 229940005483 opioid analgesics Drugs 0.000 claims 1
- 229940124636 opioid drug Drugs 0.000 claims 1
- 238000003752 polymerase chain reaction Methods 0.000 claims 1
- 238000007670 refining Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461943944P | 2014-02-24 | 2014-02-24 | |
| US61/943,944 | 2014-02-24 | ||
| PCT/US2015/017134 WO2015127379A1 (en) | 2014-02-24 | 2015-02-23 | Methods and compositions for personalized pain management |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017512069A JP2017512069A (ja) | 2017-05-18 |
| JP2017512069A5 true JP2017512069A5 (cg-RX-API-DMAC7.html) | 2018-04-05 |
| JP6581117B2 JP6581117B2 (ja) | 2019-09-25 |
Family
ID=52597325
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016570925A Expired - Fee Related JP6581117B2 (ja) | 2014-02-24 | 2015-02-23 | 個別化疼痛管理のための方法及び組成物 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US10878939B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3110968B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6581117B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR20160123385A (cg-RX-API-DMAC7.html) |
| CN (1) | CN106460042A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2015218692A1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2940422A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL247389A0 (cg-RX-API-DMAC7.html) |
| SG (1) | SG11201607035YA (cg-RX-API-DMAC7.html) |
| WO (1) | WO2015127379A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008085857A2 (en) | 2007-01-04 | 2008-07-17 | Children's Hospital Medical Center | Processing text with domain-specific spreading activation methods |
| EP3483288B1 (en) | 2011-11-30 | 2022-03-16 | Children's Hospital Medical Center | Personalized pain management and anesthesia: preemptive risk identification |
| SG11201607035YA (en) | 2014-02-24 | 2016-09-29 | Childrens Hosp Medical Center | Methods and compositions for personalized pain management |
| WO2016023026A1 (en) | 2014-08-08 | 2016-02-11 | Children's Hospital Medical Center | Diagnostic method for distinguishing forms of esophageal eosinophilia |
| JP6702686B2 (ja) * | 2015-10-09 | 2020-06-03 | 株式会社エムティーアイ | 表現型推定システム及び表現型推定プログラム |
| EP3402572B1 (en) | 2016-01-13 | 2022-03-16 | Children's Hospital Medical Center | Compositions and methods for treating allergic inflammatory conditions |
| EP3544611A4 (en) * | 2016-11-23 | 2020-09-09 | Assurex Health, Inc. | METHODS FOR TREATMENT OF OPIOID DEPENDENCE |
| WO2018136728A1 (en) | 2017-01-20 | 2018-07-26 | Children's Hospital Medical Center | Methods and compositions relating to oprm1 dna methylation for personalized pain management |
| CN113570064A (zh) * | 2017-05-05 | 2021-10-29 | 第四范式（北京）技术有限公司 | 利用复合机器学习模型来执行预测的方法及系统 |
| US11859250B1 (en) | 2018-02-23 | 2024-01-02 | Children's Hospital Medical Center | Methods for treating eosinophilic esophagitis |
| US12360103B2 (en) | 2018-04-20 | 2025-07-15 | Children's Hospital Medical Center | Blood biomarker for eosinophilic gastrointestinal disorders |
| JP7078458B2 (ja) * | 2018-05-30 | 2022-05-31 | 株式会社Soken | 操舵角決定装置、および、自動運転車 |
| CN108929913A (zh) * | 2018-08-21 | 2018-12-04 | 潍坊德诺泰克生物科技有限公司 | 用于检测rs2032582的引物探针组及其应用 |
| WO2020089835A1 (en) * | 2018-10-31 | 2020-05-07 | Ancestry.Com Dna, Llc | Estimation of phenotypes using dna, pedigree, and historical data |
| CN109741826B (zh) * | 2018-12-13 | 2022-09-13 | 华中科技大学鄂州工业技术研究院 | 麻醉评估决策树构建方法及设备 |
| WO2020140076A1 (en) * | 2018-12-28 | 2020-07-02 | Liu Xing Liang | Methods and systems for providing a personalized cannabinoid treatment regimen |
| US12297501B2 (en) | 2019-02-25 | 2025-05-13 | Children's Hospital Medical Center | Methods for diagnosing and treating eosinophilic gastritis |
| WO2020180424A1 (en) | 2019-03-04 | 2020-09-10 | Iocurrents, Inc. | Data compression and communication using machine learning |
| CN111312387A (zh) * | 2020-01-16 | 2020-06-19 | 安徽医科大学第一附属医院 | 一种男性慢性前列腺炎/慢性盆腔痛综合征疼痛严重程度预测模型及其建立 |
| WO2021262871A1 (en) * | 2020-06-25 | 2021-12-30 | Greenway Dna Inc. | Methods and systems for providing a personalized treatment regimen using cannabinoid or psychedelic compounds |
| US12499266B2 (en) | 2022-09-30 | 2025-12-16 | Cilag Gmbh International | Patient data removal |
| US12243629B2 (en) * | 2022-09-30 | 2025-03-04 | Cilag Gmbh International | Capacity to adjust patient consent |
| CN115976190B (zh) * | 2022-11-15 | 2024-08-27 | 苏州吉赛基因测序科技有限公司 | 剖宫产患者术后镇痛用药相关基因分型检测的产品及用途 |
| CN119662844A (zh) * | 2024-12-16 | 2025-03-21 | 郑州大学第一附属医院 | 用于麻醉用药基因分型的复合扩增体系、检测方法及试剂盒 |
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| US4376110A (en) | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
| US5976081A (en) | 1983-08-11 | 1999-11-02 | Silverman; Stephen E. | Method for detecting suicidal predisposition |
| US4675904A (en) | 1983-08-11 | 1987-06-23 | Compusonics, Inc. | Method for detecting suicidal predisposition |
| US5148483A (en) | 1983-08-11 | 1992-09-15 | Silverman Stephen E | Method for detecting suicidal predisposition |
| GB8810400D0 (en) | 1988-05-03 | 1988-06-08 | Southern E | Analysing polynucleotide sequences |
| US6054270A (en) | 1988-05-03 | 2000-04-25 | Oxford Gene Technology Limited | Analying polynucleotide sequences |
| US5700637A (en) | 1988-05-03 | 1997-12-23 | Isis Innovation Limited | Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays |
| US5744101A (en) | 1989-06-07 | 1998-04-28 | Affymax Technologies N.V. | Photolabile nucleoside protecting groups |
| US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| US5288644A (en) | 1990-04-04 | 1994-02-22 | The Rockefeller University | Instrument and method for the sequencing of genome |
| DE69527585T2 (de) | 1994-06-08 | 2003-04-03 | Affymetrix, Inc. | Verfahren und Vorrichtung zum Verpacken von Chips |
| US6287850B1 (en) | 1995-06-07 | 2001-09-11 | Affymetrix, Inc. | Bioarray chip reaction apparatus and its manufacture |
| US6300063B1 (en) | 1995-11-29 | 2001-10-09 | Affymetrix, Inc. | Polymorphism detection |
| JP4468488B2 (ja) | 1996-05-29 | 2010-05-26 | コーネル・リサーチ・ファンデーション・インコーポレイテッド | 組み合せたリガーゼ検出およびポリメラーゼ連鎖反応を用いる核酸配列相違の検出 |
| US6429027B1 (en) | 1998-12-28 | 2002-08-06 | Illumina, Inc. | Composite arrays utilizing microspheres |
| US8301468B2 (en) | 2000-05-15 | 2012-10-30 | Optuminsight, Inc. | System and method of drug disease matching |
| DE60134591D1 (de) | 2000-07-11 | 2008-08-07 | Kirk Hogan | Verfahren und Zusammensetzungen zur perioperativen genomischen Profilerstellung |
| US7062443B2 (en) | 2000-08-22 | 2006-06-13 | Silverman Stephen E | Methods and apparatus for evaluating near-term suicidal risk using vocal parameters |
| US7139699B2 (en) | 2000-10-06 | 2006-11-21 | Silverman Stephen E | Method for analysis of vocal jitter for near-term suicidal risk assessment |
| US20030092019A1 (en) | 2001-01-09 | 2003-05-15 | Millennium Pharmaceuticals, Inc. | Methods and compositions for diagnosing and treating neuropsychiatric disorders such as schizophrenia |
| AU2002366713A1 (en) | 2001-12-20 | 2003-07-09 | Incyte Genomics, Inc. | Nucleotide polymorphisms associated with osteoarthritis |
| US7716207B2 (en) | 2002-02-26 | 2010-05-11 | Odom Paul S | Search engine methods and systems for displaying relevant topics |
| WO2005105093A2 (en) | 2003-08-26 | 2005-11-10 | Duke University | METHOD OF ARRESTING THE SIDE EFFECTS OF µ-OPIOID RECEPTOR AGONISTS DURING THEIR ADMINISTRATION |
| EP1731606A4 (en) * | 2004-03-31 | 2008-02-13 | Tokyo Metropolitan Org Med Res | METHOD OF EVALUATING SUB-SENSITIVITY BY MEANS OF ANALYSIS OF THE MU OPIOID RECEPTOR GENE |
| WO2006119343A1 (en) | 2005-05-03 | 2006-11-09 | Children's Hospital Medical Center | Determination of eosinophilic esophagitis |
| US20090253585A1 (en) * | 2005-11-30 | 2009-10-08 | Luda Diatchenko | Identification of Genetic Polymorphic Variants Associated With Somatosensory Disorders and Methods of Using the Same |
| US7754428B2 (en) | 2006-05-03 | 2010-07-13 | The Chinese University Of Hong Kong | Fetal methylation markers |
| JP5308644B2 (ja) | 2006-08-31 | 2013-10-09 | 公益財団法人東京都医学総合研究所 | Ｇｉｒｋチャネル遺伝子解析による薬物感受性の評価方法 |
| US7899764B2 (en) | 2007-02-16 | 2011-03-01 | Siemens Aktiengesellschaft | Medical ontologies for machine learning and decision support |
| ATE555197T1 (de) | 2007-04-25 | 2012-05-15 | Tokyo Metropolitan Inst Medical Science | Verfahren zur evaluierung der wirkstoffsensitivität mittels analyse des pomc- gens |
| WO2009067473A2 (en) | 2007-11-20 | 2009-05-28 | Wisconsin Alumni Research Foundation | Method of improving palliative care |
| US8249225B2 (en) | 2008-03-14 | 2012-08-21 | International Business Machines Corporation | Identifying caller preferences based on voice print analysis |
| ES2499397T3 (es) | 2008-11-26 | 2014-09-29 | Merck Serono S.A. | Composiciones y métodos para tratar deficiencia de hormona del crecimiento |
| US8497066B2 (en) | 2008-12-04 | 2013-07-30 | Rush University Medical Center | DNA methylation based test for monitoring efficacy of treatment |
| US10204707B2 (en) | 2009-04-27 | 2019-02-12 | Children's Hospital Medical Center | Computer implemented system and method for assessing a neuropsychiatric condition of a human subject |
| GB2483108A (en) | 2010-08-27 | 2012-02-29 | Walid Juffali | Monitoring neurological electrical signals to detect the onset of a neurological episode |
| JP6053267B2 (ja) | 2010-09-03 | 2016-12-27 | 公益財団法人東京都医学総合研究所 | アドレナリン受容体遺伝子解析による薬物感受性および疾患脆弱性の評価方法 |
| US8694335B2 (en) | 2011-02-18 | 2014-04-08 | Nuance Communications, Inc. | Methods and apparatus for applying user corrections to medical fact extraction |
| US9928344B2 (en) | 2011-06-21 | 2018-03-27 | Children's Hospital Medical Center | Diagnostic methods of eosinophilic esophagitis |
| EP3483288B1 (en) | 2011-11-30 | 2022-03-16 | Children's Hospital Medical Center | Personalized pain management and anesthesia: preemptive risk identification |
| AU2013222129B2 (en) | 2012-02-24 | 2018-02-15 | Children's Hospital Medical Center | Esophageal microRNA expression profiles in eosinophilic esophagitis |
| WO2013155010A1 (en) | 2012-04-09 | 2013-10-17 | Children's Hospital Medical Center | Non-invasive biomarkers for eosinophilic esophagitis |
| US8377657B1 (en) | 2012-05-15 | 2013-02-19 | Predictive Biosciences Corporation | Primers for analyzing methylated sequences and methods of use thereof |
| WO2014059178A1 (en) | 2012-10-10 | 2014-04-17 | Rhode Island Hospital | Differential expression of novel protein markers for the diagnosis and treatment of eosinophilic esophagitis |
| WO2014190269A1 (en) | 2013-05-24 | 2014-11-27 | Children's Hospital Medical Center | System and method for assessing suicide risk of a patient based upon non-verbal characteristics of voice data |
| EP3028190B1 (en) | 2013-08-01 | 2022-06-22 | Children's Hospital Medical Center | Identification of surgery candidates using natural language processing |
| SG11201607035YA (en) | 2014-02-24 | 2016-09-29 | Childrens Hosp Medical Center | Methods and compositions for personalized pain management |
| WO2016023026A1 (en) | 2014-08-08 | 2016-02-11 | Children's Hospital Medical Center | Diagnostic method for distinguishing forms of esophageal eosinophilia |
| WO2018136728A1 (en) | 2017-01-20 | 2018-07-26 | Children's Hospital Medical Center | Methods and compositions relating to oprm1 dna methylation for personalized pain management |
| WO2020006175A1 (en) | 2018-06-28 | 2020-01-02 | Children's Hospital Medical Center | Methods and compositions relating to personalized pain management |
-
2015
- 2015-02-23 SG SG11201607035YA patent/SG11201607035YA/en unknown
- 2015-02-23 JP JP2016570925A patent/JP6581117B2/ja not_active Expired - Fee Related
- 2015-02-23 CN CN201580021042.6A patent/CN106460042A/zh active Pending
- 2015-02-23 WO PCT/US2015/017134 patent/WO2015127379A1/en not_active Ceased
- 2015-02-23 EP EP15707526.8A patent/EP3110968B1/en active Active
- 2015-02-23 AU AU2015218692A patent/AU2015218692A1/en not_active Abandoned
- 2015-02-23 CA CA2940422A patent/CA2940422A1/en not_active Abandoned
- 2015-02-23 KR KR1020167026246A patent/KR20160123385A/ko not_active Withdrawn
- 2015-02-23 US US15/120,087 patent/US10878939B2/en active Active
-
2016
- 2016-08-21 IL IL247389A patent/IL247389A0/en unknown
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