|
US4186745A
(en)
|
1976-07-30 |
1980-02-05 |
Kauzlarich James J |
Porous catheters
|
|
US4500707A
(en)
|
1980-02-29 |
1985-02-19 |
University Patents, Inc. |
Nucleosides useful in the preparation of polynucleotides
|
|
US5132418A
(en)
|
1980-02-29 |
1992-07-21 |
University Patents, Inc. |
Process for preparing polynucleotides
|
|
US4458066A
(en)
|
1980-02-29 |
1984-07-03 |
University Patents, Inc. |
Process for preparing polynucleotides
|
|
US4973679A
(en)
|
1981-03-27 |
1990-11-27 |
University Patents, Inc. |
Process for oligonucleo tide synthesis using phosphormidite intermediates
|
|
US4668777A
(en)
|
1981-03-27 |
1987-05-26 |
University Patents, Inc. |
Phosphoramidite nucleoside compounds
|
|
US4373071A
(en)
|
1981-04-30 |
1983-02-08 |
City Of Hope Research Institute |
Solid-phase synthesis of polynucleotides
|
|
SE8205892D0
(sv)
|
1982-10-18 |
1982-10-18 |
Bror Morein |
Immunogent membranproteinkomplex, sett for framstellning och anvendning derav som immunstimulerande medel och sasom vaccin
|
|
IL73534A
(en)
|
1983-11-18 |
1990-12-23 |
Riker Laboratories Inc |
1h-imidazo(4,5-c)quinoline-4-amines,their preparation and pharmaceutical compositions containing certain such compounds
|
|
US5916588A
(en)
|
1984-04-12 |
1999-06-29 |
The Liposome Company, Inc. |
Peptide-containing liposomes, immunogenic liposomes and methods of preparation and use
|
|
US6090406A
(en)
|
1984-04-12 |
2000-07-18 |
The Liposome Company, Inc. |
Potentiation of immune responses with liposomal adjuvants
|
|
US4945050A
(en)
|
1984-11-13 |
1990-07-31 |
Cornell Research Foundation, Inc. |
Method for transporting substances into living cells and tissues and apparatus therefor
|
|
US5036006A
(en)
|
1984-11-13 |
1991-07-30 |
Cornell Research Foundation, Inc. |
Method for transporting substances into living cells and tissues and apparatus therefor
|
|
US5185444A
(en)
|
1985-03-15 |
1993-02-09 |
Anti-Gene Deveopment Group |
Uncharged morpolino-based polymers having phosphorous containing chiral intersubunit linkages
|
|
WO1986005519A1
(en)
|
1985-03-15 |
1986-09-25 |
James Summerton |
Polynucleotide assay reagent and method
|
|
US5153319A
(en)
|
1986-03-31 |
1992-10-06 |
University Patents, Inc. |
Process for preparing polynucleotides
|
|
US6048729A
(en)
|
1987-05-01 |
2000-04-11 |
Transkaryotic Therapies, Inc. |
In vivo protein production and delivery system for gene therapy
|
|
US5057540A
(en)
|
1987-05-29 |
1991-10-15 |
Cambridge Biotech Corporation |
Saponin adjuvant
|
|
US4853228A
(en)
|
1987-07-28 |
1989-08-01 |
Micro-Pak, Inc. |
Method of manufacturing unilamellar lipid vesicles
|
|
JPH0731857B2
(ja)
|
1988-02-19 |
1995-04-10 |
三洋電機株式会社 |
磁気記録再生装置におけるリール台駆動装置
|
|
AU631377B2
(en)
|
1988-08-25 |
1992-11-26 |
Liposome Company, Inc., The |
Affinity associated vaccine
|
|
US5238944A
(en)
|
1988-12-15 |
1993-08-24 |
Riker Laboratories, Inc. |
Topical formulations and transdermal delivery systems containing 1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine
|
|
US5047524A
(en)
|
1988-12-21 |
1991-09-10 |
Applied Biosystems, Inc. |
Automated system for polynucleotide synthesis and purification
|
|
US5262530A
(en)
|
1988-12-21 |
1993-11-16 |
Applied Biosystems, Inc. |
Automated system for polynucleotide synthesis and purification
|
|
US5703055A
(en)
|
1989-03-21 |
1997-12-30 |
Wisconsin Alumni Research Foundation |
Generation of antibodies through lipid mediated DNA delivery
|
|
US6867195B1
(en)
|
1989-03-21 |
2005-03-15 |
Vical Incorporated |
Lipid-mediated polynucleotide administration to reduce likelihood of subject's becoming infected
|
|
US4929624A
(en)
|
1989-03-23 |
1990-05-29 |
Minnesota Mining And Manufacturing Company |
Olefinic 1H-imidazo(4,5-c)quinolin-4-amines
|
|
FR2645020B1
(fr)
|
1989-03-28 |
1994-06-10 |
Vila Jorge |
Medicament pour le traitement des maladies infectieuses dues aux retrovirus ainsi que pour le traitement des tumeurs
|
|
CA2017507C
(en)
|
1989-05-25 |
1996-11-12 |
Gary Van Nest |
Adjuvant formulation comprising a submicron oil droplet emulsion
|
|
US5013556A
(en)
|
1989-10-20 |
1991-05-07 |
Liposome Technology, Inc. |
Liposomes with enhanced circulation time
|
|
US5674192A
(en)
|
1990-12-28 |
1997-10-07 |
Boston Scientific Corporation |
Drug delivery
|
|
US5279833A
(en)
|
1990-04-04 |
1994-01-18 |
Yale University |
Liposomal transfection of nucleic acids into animal cells
|
|
US5264618A
(en)
|
1990-04-19 |
1993-11-23 |
Vical, Inc. |
Cationic lipids for intracellular delivery of biologically active molecules
|
|
US5389640A
(en)
|
1991-03-01 |
1995-02-14 |
Minnesota Mining And Manufacturing Company |
1-substituted, 2-substituted 1H-imidazo[4,5-c]quinolin-4-amines
|
|
FR2676072B1
(fr)
|
1991-05-03 |
1994-11-18 |
Transgene Sa |
Vecteur de delivrance d'arn.
|
|
US5268376A
(en)
|
1991-09-04 |
1993-12-07 |
Minnesota Mining And Manufacturing Company |
1-substituted 1H-imidazo[4,5-c]quinolin-4-amines
|
|
PT101031B
(pt)
|
1991-11-05 |
2002-07-31 |
Transkaryotic Therapies Inc |
Processo para o fornecimento de proteinas por terapia genetica
|
|
US6054288A
(en)
|
1991-11-05 |
2000-04-25 |
Transkaryotic Therapies, Inc. |
In vivo protein production and delivery system for gene therapy
|
|
US5266575A
(en)
|
1991-11-06 |
1993-11-30 |
Minnesota Mining And Manufacturing Company |
2-ethyl 1H-imidazo[4,5-ciquinolin-4-amines
|
|
US5693535A
(en)
|
1992-05-14 |
1997-12-02 |
Ribozyme Pharmaceuticals, Inc. |
HIV targeted ribozymes
|
|
US5750390A
(en)
|
1992-08-26 |
1998-05-12 |
Ribozyme Pharmaceuticals, Inc. |
Method and reagent for treatment of diseases caused by expression of the bcl-2 gene
|
|
US5340740A
(en)
|
1992-05-15 |
1994-08-23 |
North Carolina State University |
Method of producing an avian embryonic stem cell culture and the avian embryonic stem cell culture produced by the process
|
|
EP0646178A1
(en)
|
1992-06-04 |
1995-04-05 |
The Regents Of The University Of California |
expression cassette with regularoty regions functional in the mammmlian host
|
|
EP0786522A2
(en)
|
1992-07-17 |
1997-07-30 |
Ribozyme Pharmaceuticals, Inc. |
Enzymatic RNA molecules for treatment of stenotic conditions
|
|
US5474914A
(en)
|
1992-07-29 |
1995-12-12 |
Chiron Corporation |
Method of producing secreted CMV glycoprotein H
|
|
US5395937A
(en)
|
1993-01-29 |
1995-03-07 |
Minnesota Mining And Manufacturing Company |
Process for preparing quinoline amines
|
|
US20020102273A1
(en)
|
1995-08-08 |
2002-08-01 |
Robert B. Grieve |
Use of alphavirus expression vectors to produce parasite anitgens
|
|
US5776468A
(en)
|
1993-03-23 |
1998-07-07 |
Smithkline Beecham Biologicals (S.A.) |
Vaccine compositions containing 3-0 deacylated monophosphoryl lipid A
|
|
EP1624068A1
(en)
|
1993-06-01 |
2006-02-08 |
Life Technologies Inc. |
Genetic immunization with cationic lipids
|
|
US5352784A
(en)
|
1993-07-15 |
1994-10-04 |
Minnesota Mining And Manufacturing Company |
Fused cycloalkylimidazopyridines
|
|
JPH09500128A
(ja)
|
1993-07-15 |
1997-01-07 |
ミネソタ マイニング アンド マニュファクチャリング カンパニー |
イミダゾ〔4,5−c〕ピリジン−4−アミン
|
|
US6015686A
(en)
|
1993-09-15 |
2000-01-18 |
Chiron Viagene, Inc. |
Eukaryotic layered vector initiation systems
|
|
US5397307A
(en)
|
1993-12-07 |
1995-03-14 |
Schneider (Usa) Inc. |
Drug delivery PTCA catheter and method for drug delivery
|
|
GB9326174D0
(en)
|
1993-12-22 |
1994-02-23 |
Biocine Sclavo |
Mucosal adjuvant
|
|
JP3403233B2
(ja)
|
1994-01-20 |
2003-05-06 |
テルモ株式会社 |
バルーンカテーテル
|
|
AU2215995A
(en)
|
1994-04-07 |
1995-10-30 |
Akzo Nobel N.V. |
Freeze-dried compositions comprising rna
|
|
US6207646B1
(en)
|
1994-07-15 |
2001-03-27 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
|
US6239116B1
(en)
|
1994-07-15 |
2001-05-29 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
|
US6429199B1
(en)
|
1994-07-15 |
2002-08-06 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules for activating dendritic cells
|
|
US5993850A
(en)
|
1994-09-13 |
1999-11-30 |
Skyepharma Inc. |
Preparation of multivesicular liposomes for controlled release of encapsulated biologically active substances
|
|
US5885613A
(en)
|
1994-09-30 |
1999-03-23 |
The University Of British Columbia |
Bilayer stabilizing components and their use in forming programmable fusogenic liposomes
|
|
AUPM873294A0
(en)
|
1994-10-12 |
1994-11-03 |
Csl Limited |
Saponin preparations and use thereof in iscoms
|
|
FR2726003B1
(fr)
|
1994-10-21 |
2002-10-18 |
Agronomique Inst Nat Rech |
Milieu de culture de cellules embryonnaires totipotentes aviaires, procede de culture de ces cellules, et cellules embryonnaires totipotentes aviaires
|
|
AU3876695A
(en)
|
1994-11-17 |
1996-06-17 |
Imperial College Of Science, Technology And Medicine |
Internalisation of dna, using conjugates of poly-l-lysine and an integrin receptor ligand
|
|
AU4594996A
(en)
|
1994-11-30 |
1996-06-19 |
Chiron Viagene, Inc. |
Recombinant alphavirus vectors
|
|
US6071890A
(en)
|
1994-12-09 |
2000-06-06 |
Genzyme Corporation |
Organ-specific targeting of cationic amphiphile/DNA complexes for gene therapy
|
|
US5965434A
(en)
|
1994-12-29 |
1999-10-12 |
Wolff; Jon A. |
Amphipathic PH sensitive compounds and delivery systems for delivering biologically active compounds
|
|
US5482936A
(en)
|
1995-01-12 |
1996-01-09 |
Minnesota Mining And Manufacturing Company |
Imidazo[4,5-C]quinoline amines
|
|
UA56132C2
(uk)
|
1995-04-25 |
2003-05-15 |
Смітклайн Бічем Байолоджікалс С.А. |
Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини
|
|
US5700642A
(en)
|
1995-05-22 |
1997-12-23 |
Sri International |
Oligonucleotide sizing using immobilized cleavable primers
|
|
US5792462A
(en)
|
1995-05-23 |
1998-08-11 |
University Of North Carolina At Chapel Hill |
Alphavirus RNA replicon systems
|
|
US7422902B1
(en)
|
1995-06-07 |
2008-09-09 |
The University Of British Columbia |
Lipid-nucleic acid particles prepared via a hydrophobic lipid-nucleic acid complex intermediate and use for gene transfer
|
|
US5981501A
(en)
|
1995-06-07 |
1999-11-09 |
Inex Pharmaceuticals Corp. |
Methods for encapsulating plasmids in lipid bilayers
|
|
US6264957B1
(en)
|
1995-09-27 |
2001-07-24 |
The United States Of America As Represented By The Department Of Health And Human Services |
Product of infectious respiratory syncytial virus from cloned nucleotide sequences
|
|
EP0880360B1
(en)
|
1996-02-12 |
2002-10-09 |
Cobra Therapeutics Limited |
Novel methods of vaccination and vaccines therefore comprising a nucleic acid encoding a first epitope and a peptide containing a second epitope
|
|
DE19605548A1
(de)
|
1996-02-15 |
1997-09-04 |
Boehringer Ingelheim Int |
Zusammensetzung für die Transfektion höherer eukaryotischer Zellen
|
|
US6451592B1
(en)
|
1996-04-05 |
2002-09-17 |
Chiron Corporation |
Recombinant alphavirus-based vectors with reduced inhibition of cellular macromolecular synthesis
|
|
CA2259179C
(en)
|
1996-07-03 |
2008-09-23 |
University Of Pittsburgh |
Emulsion formulations for hydrophilic active agents
|
|
WO1998001148A1
(en)
|
1996-07-09 |
1998-01-15 |
President And Fellows Of Harvard College |
Use of papillomavirus e2 protein in treating papillomavirus-infected cells and compositions containing the protein
|
|
CN1138533C
(zh)
|
1996-09-13 |
2004-02-18 |
利普森有限公司 |
脂质体
|
|
US7384923B2
(en)
|
1999-05-14 |
2008-06-10 |
Lipoxen Technologies Limited |
Liposomes
|
|
US6395302B1
(en)
|
1996-11-19 |
2002-05-28 |
Octoplus B.V. |
Method for the preparation of microspheres which contain colloidal systems
|
|
DK1005368T3
(da)
|
1997-03-10 |
2010-01-04 |
Ottawa Hospital Res Inst |
Anvendelse af nukleinsyrer, der indeholder ikke-metyleret CpG dinukleotid i kombination med alun som hjælpestoffer
|
|
US6818222B1
(en)
|
1997-03-21 |
2004-11-16 |
Chiron Corporation |
Detoxified mutants of bacterial ADP-ribosylating toxins as parenteral adjuvants
|
|
AU733310C
(en)
|
1997-05-14 |
2001-11-29 |
University Of British Columbia, The |
High efficiency encapsulation of charged therapeutic agents in lipid vesicles
|
|
US6048546A
(en)
|
1997-07-31 |
2000-04-11 |
Sandia Corporation |
Immobilized lipid-bilayer materials
|
|
US6060308A
(en)
|
1997-09-04 |
2000-05-09 |
Connaught Laboratories Limited |
RNA respiratory syncytial virus vaccines
|
|
US6090619A
(en)
|
1997-09-08 |
2000-07-18 |
University Of Florida |
Materials and methods for intracellular delivery of biologically active molecules
|
|
US6129705A
(en)
|
1997-10-01 |
2000-10-10 |
Medtronic Ave, Inc. |
Drug delivery and gene therapy delivery system
|
|
GB9725084D0
(en)
|
1997-11-28 |
1998-01-28 |
Medeva Europ Ltd |
Vaccine compositions
|
|
US6009406A
(en)
|
1997-12-05 |
1999-12-28 |
Square D Company |
Methodology and computer-based tools for re-engineering a custom-engineered product line
|
|
GB9726555D0
(en)
|
1997-12-16 |
1998-02-11 |
Smithkline Beecham Plc |
Vaccine
|
|
WO1999052549A1
(en)
|
1998-04-09 |
1999-10-21 |
Smithkline Beecham Biologicals S.A. |
Adjuvant compositions
|
|
US6432925B1
(en)
|
1998-04-16 |
2002-08-13 |
John Wayne Cancer Institute |
RNA cancer vaccine and methods for its use
|
|
US6562798B1
(en)
|
1998-06-05 |
2003-05-13 |
Dynavax Technologies Corp. |
Immunostimulatory oligonucleotides with modified bases and methods of use thereof
|
|
WO2000000616A2
(en)
|
1998-06-29 |
2000-01-06 |
U.S. Medical Research Institute Of Infectious Diseases |
Marburg virus vaccines
|
|
AU747597B2
(en)
|
1998-07-20 |
2002-05-16 |
Inex Pharmaceuticals Corporation |
Liposomal encapsulated nucleic acid-complexes
|
|
GB9817052D0
(en)
|
1998-08-05 |
1998-09-30 |
Smithkline Beecham Biolog |
Vaccine
|
|
KR100629028B1
(ko)
|
1998-10-16 |
2006-09-26 |
글락소스미스클라인 바이오로지칼즈 에스.에이. |
애쥬번트 시스템 및 백신
|
|
AU2221600A
(en)
|
1998-12-31 |
2000-07-31 |
Chiron Corporation |
Improved expression of hiv polypeptides and production of virus-like particles
|
|
ES2238799T3
(es)
|
1999-09-09 |
2005-09-01 |
Curevac Gmbh |
Transferencia de arn-m.
|
|
HUP0202885A3
(en)
|
1999-09-24 |
2004-07-28 |
Smithkline Beecham Biolog |
Vaccines
|
|
TR200200777T2
(tr)
|
1999-09-24 |
2002-09-23 |
Smithkline Beecham Biologicals S.A. |
Polioksietilen alkil eteri veya esteriyle en az bir iyonik olmayan yüzey aktif maddeli adjuvant.
|
|
EP1222289B1
(en)
|
1999-10-20 |
2008-04-16 |
The Johns Hopkins University School Of Medicine |
Chimeric immunogenic compositions and nucleic acids encoding them
|
|
US8541008B2
(en)
|
1999-11-19 |
2013-09-24 |
Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center |
Pharmaceutical compositions and methods to vaccinate against candidiasis
|
|
US20010044416A1
(en)
|
2000-01-20 |
2001-11-22 |
Mccluskie Michael J. |
Immunostimulatory nucleic acids for inducing a Th2 immune response
|
|
US20030212022A1
(en)
|
2001-03-23 |
2003-11-13 |
Jean-Marie Vogel |
Compositions and methods for gene therapy
|
|
EP1287015A1
(en)
|
2000-04-18 |
2003-03-05 |
Human Genome Sciences, Inc. |
Extracellular matrix polynucleotides, polypeptides, and antibodies
|
|
AU2001275423B2
(en)
|
2000-06-09 |
2007-01-11 |
Regulon, Inc. |
Encapsulation of polynucleotides and drugs into targeted liposomes
|
|
JP2004502415A
(ja)
|
2000-07-03 |
2004-01-29 |
カイロン エセ.ピー.アー. |
Chlamydiapneumoniaeに対する免疫化
|
|
AU2001290520A1
(en)
*
|
2000-08-01 |
2002-02-13 |
The Johns Hokpins University |
Intercellular transport protein linked to an antigen as a molecular vaccine
|
|
US20040142474A1
(en)
|
2000-09-14 |
2004-07-22 |
Expression Genetics, Inc. |
Novel cationic lipopolymer as a biocompatible gene delivery agent
|
|
AU2001294750C1
(en)
|
2000-09-26 |
2008-09-18 |
Idera Pharmaceuticals, Inc. |
Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes
|
|
ES2260291T3
(es)
|
2000-09-28 |
2006-11-01 |
Chiron Corporation |
Microparticulas para la administracion de acidos nucleicos heterologos.
|
|
CA2881568C
(en)
|
2000-10-27 |
2019-09-24 |
Novartis Vaccines And Diagnostics, Inc. |
Nucleic acids and proteins from streptococcus groups a & b
|
|
US7731975B2
(en)
|
2001-01-31 |
2010-06-08 |
The United States Of America As Represented By The Secretary Of The Army |
Chimeric filovirus glycoprotein
|
|
WO2002061113A2
(en)
|
2001-02-01 |
2002-08-08 |
The Johns Hopkins University |
Nucleic acid derived vaccine that encodes an antigen linked to a polypeptide that promotes antigen presentation
|
|
US20030040498A1
(en)
|
2001-03-14 |
2003-02-27 |
Ansardi David Calvert |
Oncolytic RNA replicons
|
|
JP2004535388A
(ja)
|
2001-04-30 |
2004-11-25 |
ターゲティッド ジェネティクス コーポレイション |
脂質含有薬物送達複合体およびそれらの生成方法
|
|
US20030077251A1
(en)
|
2001-05-23 |
2003-04-24 |
Nicolas Escriou |
Replicons derived from positive strand RNA virus genomes useful for the production of heterologous proteins
|
|
ES2340499T3
(es)
|
2001-06-05 |
2010-06-04 |
Curevac Gmbh |
Arnm de antigeno tumoral estabilizado con un contenido de g/c aumentado.
|
|
WO2003018054A1
(en)
|
2001-08-31 |
2003-03-06 |
Chiron Srl. |
Helicobacter pylori vaccination
|
|
ES2330202T5
(es)
|
2001-09-06 |
2014-01-20 |
Alphavax, Inc. |
Sistemas vectores basados en replicones de alfavirus
|
|
CA2492823A1
(en)
|
2001-09-14 |
2003-03-27 |
Cytos Biotechnology Ag |
In vivo activation of antigen presenting cells for enhancement of immune responses induced by virus like particles
|
|
DE60234375D1
(de)
|
2001-09-14 |
2009-12-24 |
Cytos Biotechnology Ag |
VERPACKUNG VON IMMUNSTIMULIERENDEM CpG IN VIRUSÄHNLICHEN PARTIKELN: HERSTELLUNGSVERFAHREN UND VERWENDUNG
|
|
WO2003035836A2
(en)
|
2001-10-24 |
2003-05-01 |
Hybridon Inc. |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends
|
|
FR2832423B1
(fr)
|
2001-11-22 |
2004-10-08 |
Vivalis |
Systeme d'expression de proteines exogenes dans un systeme aviaire
|
|
AU2003211103A1
(en)
|
2002-02-13 |
2003-09-04 |
Northeastern University |
Intracellular delivery of therapeutic agents
|
|
DE10207177A1
(de)
|
2002-02-19 |
2003-09-04 |
Novosom Ag |
Fakultativ kationische Lipide
|
|
FR2836924B1
(fr)
|
2002-03-08 |
2005-01-14 |
Vivalis |
Lignees de cellules aviaires utiles pour la production de substances d'interet
|
|
EP1519714B1
(en)
|
2002-06-28 |
2010-10-20 |
Protiva Biotherapeutics Inc. |
Method and apparatus for producing liposomes
|
|
US7604803B2
(en)
|
2002-07-05 |
2009-10-20 |
Lipoxen Technologies Limited |
Method to enhance an immune response of nucleic acid vaccination
|
|
WO2004018506A2
(en)
|
2002-08-22 |
2004-03-04 |
Cytos Biotechnology Ag |
Inducible alphaviral/orip based gene expression system
|
|
BR0314236A
(pt)
|
2002-09-13 |
2005-08-09 |
Replicor Inc |
Formulação de oligonucleotìdeo, composição farmacêutica, kit, composto antiviral, preparação de oligonucleotìdeo e métodos para seleção de um oligonucleotìdeo antiviral para uso como um agente antiviral, para profilaxia ou tratamento de uma infecção viral em um paciente, para tratamento profilático de câncer causado por oncovìrus, para identificação de um composto que altera a ligação de um oligonucleotìdeo a pelo menos um componente viral, para purificação da ligação de oligonucleotìdeos a pelo menos um componente viral e para enriquecimento de oligonucleotìdeos a partir de um agrupamento de oligonucleotìdeos
|
|
US20040208848A1
(en)
*
|
2002-12-13 |
2004-10-21 |
Smith Jonathan F. |
Multi-antigenic alphavirus replicon particles and methods
|
|
DK2311848T3
(da)
|
2002-12-23 |
2013-10-14 |
Vical Inc |
Kodon-optimerede polynukleotidbaserede vacciner mod human cytomegalovirus-infektion
|
|
US7521062B2
(en)
|
2002-12-27 |
2009-04-21 |
Novartis Vaccines & Diagnostics, Inc. |
Thiosemicarbazones as anti-virals and immunopotentiators
|
|
CA2513655C
(en)
|
2003-01-21 |
2011-11-22 |
Chiron Corporation |
Use of tryptanthrin compounds for immune potentiation
|
|
WO2004069148A2
(en)
|
2003-02-04 |
2004-08-19 |
Bar-Ilan University |
Snornai-small nucleolar rna degradation by rna interference in trypanosomatids
|
|
US20040228842A1
(en)
|
2003-02-27 |
2004-11-18 |
Shan Lu |
Compositions and methods for cytomegalovirus treatment
|
|
US7442381B2
(en)
*
|
2003-03-20 |
2008-10-28 |
Alphavax, Inc. |
Alphavirus replicons and helper constructs
|
|
DE10319208B4
(de)
|
2003-04-29 |
2005-10-20 |
Grenzebach Bsh Gmbh |
Furniermessermaschine
|
|
EP1637144A4
(en)
|
2003-05-30 |
2010-01-13 |
Nippon Shinyaku Co Ltd |
OLIGONUCLEIC ACID CONTAINING COMPOSITE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME
|
|
MXPA05013260A
(es)
|
2003-06-26 |
2006-03-09 |
Chiron Corp |
Composiciones inmunogenicas para chlamydia trachomatis.
|
|
DE602004021260D1
(de)
|
2003-07-11 |
2009-07-09 |
Alphavax Inc |
Cytomegalovirusimpfstoffe, die auf dem alphavirus basieren
|
|
US7368537B2
(en)
|
2003-07-15 |
2008-05-06 |
Id Biomedical Corporation Of Quebec |
Subunit vaccine against respiratory syncytial virus infection
|
|
CA2532228C
(en)
|
2003-07-16 |
2017-02-14 |
Protiva Biotherapeutics, Inc. |
Lipid encapsulated interfering rna
|
|
ES2505695T3
(es)
|
2003-07-31 |
2014-10-10 |
Novartis Vaccines And Diagnostics, Inc. |
Composiciones inmunógenas para Streptococcus pyogenes
|
|
EP1512393A1
(de)
|
2003-09-08 |
2005-03-09 |
BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG |
Verfahren zur Herstellung von homogenen Liposomen und Lipoplexen
|
|
EP1528101A1
(en)
|
2003-11-03 |
2005-05-04 |
ProBioGen AG |
Immortalized avian cell lines for virus production
|
|
EP1687033A4
(en)
|
2003-11-12 |
2008-06-11 |
Us Navy |
IMPROVEMENT OF VACCINE-INDUCED IMMUNE REACTIONS AND PROTECTION THROUGH HETEROLOGY REINFORCEMENT WITH ALPHAVIRUS REPLICON VACCINE
|
|
US20120027841A1
(en)
|
2004-01-07 |
2012-02-02 |
Biomedical Research Models, Inc. |
Novel mucosal vaccination approach for herpes simplex virus type-2
|
|
US7303881B2
(en)
|
2004-04-30 |
2007-12-04 |
Pds Biotechnology Corporation |
Antigen delivery compositions and methods of use
|
|
GB0410866D0
(en)
|
2004-05-14 |
2004-06-16 |
Chiron Srl |
Haemophilius influenzae
|
|
CN1989250B
(zh)
|
2004-05-18 |
2013-11-20 |
阿尔法瓦克斯公司 |
Tc-83衍生的甲病毒属载体、颗粒和方法
|
|
JP5331340B2
(ja)
|
2004-05-18 |
2013-10-30 |
バイカル インコーポレイテッド |
インフルエンザウィルスワクチン組成物、及びその使用方法
|
|
EP2848692B1
(en)
|
2004-05-21 |
2017-08-16 |
Novartis Vaccines and Diagnostics, Inc. |
Alphavirus vectors for influenza virus vaccines
|
|
GB0411428D0
(en)
|
2004-05-21 |
2004-06-23 |
Got A Gene Ab |
Vectors
|
|
CA2569664C
(en)
|
2004-06-07 |
2013-07-16 |
Protiva Biotherapeutics, Inc. |
Lipid encapsulated interfering rna
|
|
JP4764426B2
(ja)
|
2004-06-07 |
2011-09-07 |
プロチバ バイオセラピューティクス インコーポレイティッド |
カチオン性脂質および使用方法
|
|
EP1773403B1
(en)
*
|
2004-07-09 |
2018-04-25 |
The University of North Carolina At Chapel Hill |
Alphavirus-based adjuvants
|
|
US20060051405A1
(en)
|
2004-07-19 |
2006-03-09 |
Protiva Biotherapeutics, Inc. |
Compositions for the delivery of therapeutic agents and uses thereof
|
|
EP2149583B1
(en)
|
2004-09-24 |
2015-10-28 |
Novartis AG |
Modified VP1-capsid protein of parvovirus B19
|
|
JP5086082B2
(ja)
|
2004-10-01 |
2012-11-28 |
ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル |
C型肝炎ウイルス複製系
|
|
JP2008520600A
(ja)
|
2004-11-19 |
2008-06-19 |
ノヴォソム アクチェンゲゼルシャフト |
局所投与のための医薬組成物におけるまたはそれに関する改善
|
|
GB2421025A
(en)
|
2004-12-09 |
2006-06-14 |
Oxxon Therapeutics Ltd |
HSV vaccination vectors
|
|
WO2007086881A2
(en)
|
2005-02-14 |
2007-08-02 |
Sirna Therapeutics, Inc. |
Cationic lipids and formulated molecular compositions containing them
|
|
US7404969B2
(en)
|
2005-02-14 |
2008-07-29 |
Sirna Therapeutics, Inc. |
Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules
|
|
JP2008530245A
(ja)
|
2005-02-18 |
2008-08-07 |
ノバルティス ヴァクシンズ アンド ダイアグノスティクス, インコーポレイテッド |
尿路病原性菌株由来の抗原
|
|
SI1858920T1
(sl)
|
2005-02-18 |
2016-07-29 |
Glaxosmithkline Biologicals S.A. |
Proteini in nukleinske kisline iz escherichia coli, povezane z meningitisom/sepso
|
|
US20080138431A1
(en)
|
2005-03-02 |
2008-06-12 |
James Edward Eyles |
Pharmaceutical Composition
|
|
GB0504436D0
(en)
|
2005-03-03 |
2005-04-06 |
Glaxosmithkline Biolog Sa |
Vaccine
|
|
EP1871888A4
(en)
|
2005-03-30 |
2013-08-21 |
Novartis Vaccines & Diagnostic |
HAEMOPHILUS INFLUENZAE OF TYPE B
|
|
US7618393B2
(en)
|
2005-05-03 |
2009-11-17 |
Pharmajet, Inc. |
Needle-less injector and method of fluid delivery
|
|
RU2007146137A
(ru)
|
2005-05-12 |
2009-06-27 |
Новартис Вэксинес Энд Дайэгностикс, Инк. (Us) |
Иммуногенные композиции на основе chlamydia trachomatis
|
|
US8703095B2
(en)
|
2005-07-07 |
2014-04-22 |
Sanofi Pasteur S.A. |
Immuno-adjuvant emulsion
|
|
EP1909758A1
(en)
|
2005-08-02 |
2008-04-16 |
I.D.M. Immuno-Designed Molecules |
Process for the preparation of liposomal formulations
|
|
US7951384B2
(en)
|
2005-08-05 |
2011-05-31 |
University Of Massachusetts |
Virus-like particles as vaccines for paramyxovirus
|
|
PL2578685T3
(pl)
|
2005-08-23 |
2020-01-31 |
The Trustees Of The University Of Pennsylvania |
Rna zawierający zmodyfikowane nukleozydy i sposoby jego zastosowania
|
|
EP1764089A1
(en)
|
2005-09-15 |
2007-03-21 |
Novosom AG |
Serum stable liposomes comprising amphoter II lipid mixtures
|
|
DE102005046490A1
(de)
|
2005-09-28 |
2007-03-29 |
Johannes-Gutenberg-Universität Mainz |
Modifikationen von RNA, die zu einer erhöhten Transkriptstabilität und Translationseffizienz führen
|
|
BRPI0616687A2
(pt)
|
2005-09-29 |
2011-06-28 |
Elan Pharm Inc |
compostos de pirimidinil amida que inibem a adesão leucocitária mediada por vla-4
|
|
CA2626253A1
(en)
|
2005-10-18 |
2007-04-26 |
Novartis Vaccines And Diagnostics, Inc. |
Mucosal and systemic immunizations with alphavirus replicon particles
|
|
JP2007112768A
(ja)
|
2005-10-24 |
2007-05-10 |
Kyoto Univ |
肝指向性リポソーム組成物
|
|
EP1954306A2
(en)
|
2005-10-25 |
2008-08-13 |
Novartis Vaccines and Diagnostics S.r.l. |
Compositions comprising yersinia pestis antigens
|
|
ES2514316T3
(es)
|
2005-11-22 |
2014-10-28 |
Novartis Vaccines And Diagnostics, Inc. |
Partículas similares a virus (VLPs) de Norovirus y Sapovirus
|
|
CA2631714C
(en)
|
2005-12-02 |
2014-09-16 |
Novartis Ag |
Nanoparticles for use in immunogenic compositions
|
|
EP2004141A2
(en)
|
2006-03-17 |
2008-12-24 |
Novosom AG |
An efficient method for loading amphoteric liposomes with nucleic acid active substances
|
|
EP3031469B1
(en)
|
2006-06-07 |
2023-08-23 |
The Trustees Of Princeton University |
Cytomegalovirus surface protein complex for use in vaccines and as a drug target
|
|
US7915399B2
(en)
|
2006-06-09 |
2011-03-29 |
Protiva Biotherapeutics, Inc. |
Modified siRNA molecules and uses thereof
|
|
PT2035581E
(pt)
|
2006-06-21 |
2012-12-06 |
Scripps Research Inst |
Composição de adn contra o antigénio do estroma tumoral fap e métodos de utilização desta
|
|
EP2586790A3
(en)
|
2006-08-16 |
2013-08-14 |
Novartis AG |
Immunogens from uropathogenic Escherichia coli
|
|
ES2987072T3
(es)
|
2006-09-07 |
2024-11-13 |
Scott & White Memorial Hospital |
Métodos y composiciones basados en conjugados de toxina diftérica-interleucina-3
|
|
CA2663295C
(en)
|
2006-09-12 |
2020-03-10 |
Alphavax, Inc. |
Alphavirus replicon particles matched to protein antigens as immunological adjuvants
|
|
DE102007001370A1
(de)
|
2007-01-09 |
2008-07-10 |
Curevac Gmbh |
RNA-kodierte Antikörper
|
|
CA2689042A1
(en)
|
2007-02-16 |
2008-08-28 |
Merck & Co., Inc. |
Compositions and methods for potentiated activity of biologicaly active molecules
|
|
US20100196492A1
(en)
|
2007-03-08 |
2010-08-05 |
Green Jordan J |
Electrostatic coating of particles for drug delivery
|
|
US8877206B2
(en)
|
2007-03-22 |
2014-11-04 |
Pds Biotechnology Corporation |
Stimulation of an immune response by cationic lipids
|
|
EP2905336A1
(en)
|
2007-03-29 |
2015-08-12 |
Alnylam Pharmaceuticals Inc. |
Compositions and methods for inhibiting expression of a gene from the ebola
|
|
US8748591B2
(en)
|
2007-04-17 |
2014-06-10 |
The Board Of Regents Of The University Of Texas System |
Chimeric sindbis-western equine encephalitis virus and uses thereof
|
|
HUE040417T2
(hu)
|
2007-05-04 |
2019-03-28 |
Marina Biotech Inc |
Aminosavlipidek és alkalmazásuk
|
|
WO2008148068A1
(en)
|
2007-05-23 |
2008-12-04 |
Mannkind Corporation |
Multicistronic vectors and methods for their design
|
|
DE102007029471A1
(de)
|
2007-06-20 |
2008-12-24 |
Novosom Ag |
Neue fakultativ kationische Sterole
|
|
US8460913B2
(en)
|
2007-06-21 |
2013-06-11 |
Alpha Vax, Inc. |
Promoterless cassettes for expression of alpha virus structural proteins
|
|
EP2173771A1
(en)
|
2007-07-04 |
2010-04-14 |
Ribovax Biotechnologies SA |
Antibodies against human cytomegalovirus (hcmv)
|
|
GB0714963D0
(en)
|
2007-08-01 |
2007-09-12 |
Novartis Ag |
Compositions comprising antigens
|
|
WO2009026328A2
(en)
|
2007-08-21 |
2009-02-26 |
Immune Disease Institute, Inc. |
Methods of delivery of agents to leukocytes and endothelial cells
|
|
GB0717187D0
(en)
|
2007-09-04 |
2007-10-17 |
Novartis Ag |
Compositions comprising yersinia pestis antigens
|
|
CA2704153A1
(en)
|
2007-09-26 |
2009-04-02 |
Vanderbilt University |
Vaccine for rsv and mpv
|
|
EP2042193A1
(en)
|
2007-09-28 |
2009-04-01 |
Biomay AG |
RNA Vaccines
|
|
US20090091591A1
(en)
|
2007-10-07 |
2009-04-09 |
Yohanan Sivan |
Printing Systems And Methods For Generating Relief Images
|
|
AU2008338803B2
(en)
|
2007-11-26 |
2015-02-05 |
Glaxosmithkline Biologicals S.A. |
Methods of generating alphavirus particles
|
|
EP2067749A1
(en)
|
2007-11-29 |
2009-06-10 |
Total Petrochemicals France |
Process for purification of an aqueous phase containing polyaromatics
|
|
WO2009074861A2
(en)
|
2007-12-10 |
2009-06-18 |
Powderject Research Limited |
Improved vaccine
|
|
WO2009111088A2
(en)
|
2008-01-02 |
2009-09-11 |
The Johns Hopkins University |
Antitumor immunization by liposomal delivery of vaccine to the spleen
|
|
WO2009086558A1
(en)
|
2008-01-02 |
2009-07-09 |
Tekmira Pharmaceuticals Corporation |
Improved compositions and methods for the delivery of nucleic acids
|
|
ITMI20081249A1
(it)
|
2008-07-09 |
2010-01-09 |
Novartis Vaccines & Diagnostic |
Immunogeni di escherichia coli con solubilità migliorata.
|
|
CN102015651B
(zh)
|
2008-03-03 |
2014-12-31 |
Irm责任有限公司 |
作为tlr活性调节剂的化合物和组合物
|
|
WO2009109860A2
(en)
|
2008-03-06 |
2009-09-11 |
Novartis Ag |
Mutant forms of chlamydia htra
|
|
CA2721333C
(en)
|
2008-04-15 |
2020-12-01 |
Protiva Biotherapeutics, Inc. |
Novel lipid formulations for nucleic acid delivery
|
|
WO2009127230A1
(en)
|
2008-04-16 |
2009-10-22 |
Curevac Gmbh |
MODIFIED (m)RNA FOR SUPPRESSING OR AVOIDING AN IMMUNOSTIMULATORY RESPONSE AND IMMUNOSUPPRESSIVE COMPOSITION
|
|
WO2009132131A1
(en)
|
2008-04-22 |
2009-10-29 |
Alnylam Pharmaceuticals, Inc. |
Amino lipid based improved lipid formulation
|
|
WO2009132206A1
(en)
|
2008-04-25 |
2009-10-29 |
Liquidia Technologies, Inc. |
Compositions and methods for intracellular delivery and release of cargo
|
|
US20100040650A1
(en)
|
2008-05-30 |
2010-02-18 |
Crowe Jr James E |
Virus-Like paramyxovirus particles and vaccines
|
|
EP2130912A1
(en)
|
2008-06-04 |
2009-12-09 |
Institut für Viruskrankeiten und Immunprophylaxe |
Pestivirus replicons providing an RNA-based viral vector system
|
|
EP2310045A1
(en)
|
2008-06-25 |
2011-04-20 |
Novartis AG |
Rapid responses to delayed booster immunisations
|
|
US20110229969A1
(en)
|
2008-06-25 |
2011-09-22 |
Volker Sandig |
Cell Line for Propagation of Highly Attenuated AlphaViruses
|
|
DK2352759T3
(en)
|
2008-07-16 |
2017-12-18 |
Inst Res Biomedicine |
ANTIBODIES THAT NEUTRALIZE HUMAN CYTOMEGALOVIRUS AND USE THEREOF
|
|
JP2010025644A
(ja)
|
2008-07-16 |
2010-02-04 |
Kochi Univ Of Technology |
硝酸イオンの呈色試薬並びにこれを用いた硝酸イオンの検出及び定量方法
|
|
AU2008359583B2
(en)
|
2008-07-16 |
2012-04-05 |
Institute For Research In Biomedicine |
Human cytomegalovirus neutralising antibodies and use thereof
|
|
CA2733147A1
(en)
*
|
2008-08-06 |
2010-02-11 |
Novartis Ag |
Microparticles for use in immunogenic compositions
|
|
CL2008002322A1
(es)
|
2008-08-07 |
2009-06-05 |
Univ Concepcion |
Formulacion farmaceutica veterinaria que comprende un sistema vectorial viral constituido por una particula recombinante de arn que codifica una cu/zn superoxido dismutasa de la bacteria patogena de bovinos brucella abortus, y al menos un alfavirus arn perteneciente a la familia del virus semliki forest (sfv), util como vacuna.
|
|
US8557292B2
(en)
|
2008-08-13 |
2013-10-15 |
California Institute Of Technology |
Carrier nanoparticles and related compositions, methods and systems
|
|
WO2010036948A2
(en)
|
2008-09-26 |
2010-04-01 |
The United States Of America, As Represented By The Secretary, Department Of Health & Human Services |
Dna prime/inactivated vaccine boost immunization to influenza virus
|
|
CA2740000C
(en)
|
2008-10-09 |
2017-12-12 |
Tekmira Pharmaceuticals Corporation |
Improved amino lipids and methods for the delivery of nucleic acids
|
|
EP3269395A1
(en)
|
2008-11-07 |
2018-01-17 |
Massachusetts Institute Of Technology |
Aminoalcohol lipidoids and uses thereof
|
|
CN111808084A
(zh)
|
2008-11-10 |
2020-10-23 |
阿布特斯生物制药公司 |
用于递送治疗剂的新型脂质和组合物
|
|
JP6046348B2
(ja)
|
2008-11-18 |
2016-12-14 |
タケダ ヴァクシーンズ, インコーポレイテッド |
Rsvfvlpならびにその製造および使用の方法
|
|
EP3243504A1
(en)
|
2009-01-29 |
2017-11-15 |
Arbutus Biopharma Corporation |
Improved lipid formulation
|
|
EP3263128A3
(en)
|
2009-04-14 |
2018-01-24 |
GlaxoSmithKline Biologicals S.A. |
Compositions for immunising against staphylococcus aureus
|
|
CA3045126A1
(en)
|
2009-05-05 |
2010-11-11 |
Arbutus Biopharma Corporation |
Methods of delivering oligonucleotides to immune cells
|
|
KR101766408B1
(ko)
|
2009-06-10 |
2017-08-10 |
알닐람 파마슈티칼스 인코포레이티드 |
향상된 지질 조성물
|
|
WO2011000107A1
(en)
|
2009-07-01 |
2011-01-06 |
Protiva Biotherapeutics, Inc. |
Novel lipid formulations for delivery of therapeutic agents to solid tumors
|
|
EP2450031B1
(en)
|
2009-07-02 |
2018-08-29 |
Konica Minolta Holdings, Inc. |
Method for producing liposomes by two-stage emulsification method using outer aqueous phase containing specific dispersing agent, method for producing liposome dispersion or dry powder thereof using the method for producing liposomes, and liposome dispersion or dry powder thereof produced thereby
|
|
CA2766907A1
(en)
|
2009-07-06 |
2011-01-13 |
Novartis Ag |
Self replicating rna molecules and uses thereof
|
|
CA2768186A1
(en)
|
2009-07-15 |
2011-01-20 |
Novartis Ag |
Rsv f protein compositions and methods for making same
|
|
US8277919B2
(en)
|
2009-07-23 |
2012-10-02 |
VMO Systems, Inc. |
Reflective coating for an optical disc
|
|
CA2769670C
(en)
|
2009-07-31 |
2018-10-02 |
Ethris Gmbh |
Rna with a combination of unmodified and modified nucleotides for protein expression
|
|
WO2011027222A2
(en)
*
|
2009-09-02 |
2011-03-10 |
Novartis Ag |
Immunogenic compositions including tlr activity modulators
|
|
JO3257B1
(ar)
*
|
2009-09-02 |
2018-09-16 |
Novartis Ag |
مركبات وتركيبات كمعدلات لفاعلية tlr
|
|
US20110070260A1
(en)
|
2009-09-09 |
2011-03-24 |
Baric Ralph S |
Multivalent Immunogenic Compositions Against Noroviruses and Methods of Use
|
|
CN107028886A
(zh)
|
2009-11-04 |
2017-08-11 |
不列颠哥伦比亚大学 |
含有核酸的脂质粒子及相关的方法
|
|
EP3318248B1
(en)
|
2009-12-01 |
2019-04-10 |
Translate Bio, Inc. |
Delivery of mrna for the augmentation of proteins and enzymes in human genetic diseases
|
|
US8808982B2
(en)
|
2009-12-07 |
2014-08-19 |
Cellscript, Llc |
Compositions and methods for reprogramming eukaryotic cells
|
|
EP3296398A1
(en)
|
2009-12-07 |
2018-03-21 |
Arbutus Biopharma Corporation |
Compositions for nucleic acid delivery
|
|
EP3494963A1
(en)
|
2009-12-18 |
2019-06-12 |
The University of British Columbia |
Methods and compositions for delivery of nucleic acids
|
|
CA3009891C
(en)
|
2009-12-23 |
2020-09-15 |
Novartis Ag |
Lipids, lipid compositions, and methods of using them
|
|
EP2525815B1
(en)
*
|
2010-01-24 |
2015-02-25 |
Novartis AG |
Irradiated biodegradable polymer microparticles
|
|
US9744228B2
(en)
|
2010-04-07 |
2017-08-29 |
Norvartis Ag |
Method for generating a parvovirus B19 virus-like particle
|
|
NZ606591A
(en)
*
|
2010-07-06 |
2015-02-27 |
Novartis Ag |
Cationic oil-in-water emulsions
|
|
ES2646669T3
(es)
|
2010-07-06 |
2017-12-14 |
Glaxosmithkline Biologicals Sa |
Procedimientos de aumento de una respuesta inmunitaria mediante el suministro de ARN
|
|
ES2557382T3
(es)
|
2010-07-06 |
2016-01-25 |
Glaxosmithkline Biologicals Sa |
Liposomas con lípidos que tienen un valor de pKa ventajoso para el suministro de ARN
|
|
AU2011276328C1
(en)
*
|
2010-07-06 |
2016-01-21 |
Novartis Ag |
Norovirus derived immunogenic compositions and methods
|
|
EP2591114B1
(en)
*
|
2010-07-06 |
2016-06-08 |
GlaxoSmithKline Biologicals SA |
Immunisation of large mammals with low doses of rna
|
|
US9770463B2
(en)
|
2010-07-06 |
2017-09-26 |
Glaxosmithkline Biologicals Sa |
Delivery of RNA to different cell types
|
|
US9192661B2
(en)
*
|
2010-07-06 |
2015-11-24 |
Novartis Ag |
Delivery of self-replicating RNA using biodegradable polymer particles
|
|
MX342608B
(es)
*
|
2010-07-06 |
2016-10-06 |
Novartis Ag * |
Particulas de suministro similares a viriones para moleculas de arn de autorreplicacion.
|
|
US8898852B2
(en)
|
2010-08-04 |
2014-12-02 |
Honeywell International Inc. |
Air burst to clear detection window
|
|
WO2012019168A2
(en)
|
2010-08-06 |
2012-02-09 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
LT4226941T
(lt)
|
2010-08-31 |
2025-01-10 |
Glaxosmithkline Biologicals Sa |
Pegilintos liposomos, skirtos imunogeną koduojančios rnr pristatymui
|
|
SI4043040T1
(sl)
|
2010-08-31 |
2023-04-28 |
Glaxosmithkline Biologicals Sa |
Mali liposomi za dostavo imunogen-kodirajoče RNA
|
|
MX2013002332A
(es)
*
|
2010-08-31 |
2013-03-18 |
Novartis Ag |
Lipidos apropiados para suministro liposomal del arn que codifica la proteina.
|
|
EP2614072A4
(en)
*
|
2010-09-09 |
2014-03-19 |
Univ Virginia Commonwealth |
VACCINE AGAINST THE HUMAN CYTOMEGALOVIRUS
|
|
EP2625189B1
(en)
|
2010-10-01 |
2018-06-27 |
ModernaTX, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
WO2012051211A2
(en)
|
2010-10-11 |
2012-04-19 |
Novartis Ag |
Antigen delivery platforms
|
|
PH12013500764A1
(en)
|
2010-10-25 |
2015-09-23 |
Stepan Co |
Quaternized fatty amines, amidoamines, and their derivatives from natural oil metathesis
|
|
US20120177701A1
(en)
|
2010-12-31 |
2012-07-12 |
Selecta Biosciences, Inc. |
Compositions comprising immunostimulatory nucleic acids and related methods
|
|
WO2012103361A1
(en)
*
|
2011-01-26 |
2012-08-02 |
Novartis Ag |
Rsv immunization regimen
|
|
EA033467B1
(ru)
|
2011-01-31 |
2019-10-31 |
Univ Pennsylvania |
Молекула нуклеиновой кислоты для индукции иммунного ответа против герпесвируса и ее применение
|
|
WO2012116714A1
(en)
|
2011-03-02 |
2012-09-07 |
Curevac Gmbh |
Vaccination in elderly patients
|
|
AU2012236099A1
(en)
|
2011-03-31 |
2013-10-03 |
Moderna Therapeutics, Inc. |
Delivery and formulation of engineered nucleic acids
|
|
CA2835644C
(en)
*
|
2011-05-13 |
2021-06-15 |
Novartis Ag |
Pre-fusion rsv f antigens
|
|
CA2835428A1
(en)
|
2011-05-17 |
2012-11-22 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof for non-human vertebrates
|
|
RU2013154295A
(ru)
|
2011-06-08 |
2015-07-20 |
Шир Хьюман Дженетик Терапис, Инк. |
КОМПОЗИЦИИ ЛИПИДНЫХ НАНОЧАСТИЦ И СПОСОБЫ ДЛЯ ДОСТАВКИ мРНК
|
|
ES2795110T3
(es)
|
2011-06-08 |
2020-11-20 |
Translate Bio Inc |
Lípidos escindibles
|
|
EP4115875A1
(en)
|
2011-07-06 |
2023-01-11 |
GlaxoSmithKline Biologicals S.A. |
Liposomes having useful n:p ratio for delivery of rna molecules
|
|
CA2841047A1
(en)
|
2011-07-06 |
2013-01-10 |
Novartis Ag |
Immunogenic compositions and uses thereof
|
|
EP2729165B1
(en)
*
|
2011-07-06 |
2017-11-08 |
GlaxoSmithKline Biologicals SA |
Immunogenic combination compositions and uses thereof
|
|
JP6059220B2
(ja)
*
|
2011-07-06 |
2017-01-18 |
ノバルティス アーゲー |
核酸を含む水中油型エマルジョン
|
|
MX350258B
(es)
|
2011-07-06 |
2017-08-31 |
Novartis Ag |
Emulsiones cationicas de aceite en agua.
|
|
MX366055B
(es)
|
2011-08-31 |
2019-06-26 |
Novartis Ag |
Liposomas pegilados para admistracion de acido ribonucleico (arn) que codifica para inmunogeno.
|
|
WO2013039861A2
(en)
|
2011-09-12 |
2013-03-21 |
modeRNA Therapeutics |
Engineered nucleic acids and methods of use thereof
|
|
DE19216461T1
(de)
|
2011-10-03 |
2021-10-07 |
Modernatx, Inc. |
Modifizierte nukleoside, nukleotide und nukleinsäuren und verwendungen davon
|
|
RU2014118727A
(ru)
*
|
2011-10-11 |
2015-11-20 |
Новартис Аг |
Рекомбинантные самореплицирующиеся полицистронные молекулы рнк
|
|
US20140348863A1
(en)
*
|
2011-10-12 |
2014-11-27 |
Alessia Bianchi |
Cmv antigens and uses thereof
|
|
WO2013130161A1
(en)
|
2011-12-14 |
2013-09-06 |
modeRNA Therapeutics |
Methods of responding to a biothreat
|
|
CA3018046A1
(en)
|
2011-12-16 |
2013-06-20 |
Moderna Therapeutics, Inc. |
Modified nucleoside, nucleotide, and nucleic acid compositions
|
|
CN104968354A
(zh)
|
2011-12-21 |
2015-10-07 |
现代治疗公司 |
增加器官或器官外植体的活力或寿命的方法
|
|
WO2013151665A2
(en)
|
2012-04-02 |
2013-10-10 |
modeRNA Therapeutics |
Modified polynucleotides for the production of proteins associated with human disease
|
|
CN104411338A
(zh)
|
2012-04-02 |
2015-03-11 |
现代治疗公司 |
用于产生与人类疾病相关的生物制剂和蛋白质的修饰多核苷酸
|
|
PL2922554T3
(pl)
|
2012-11-26 |
2022-06-20 |
Modernatx, Inc. |
Na zmodyfikowany na końcach
|
|
CN109045294A
(zh)
*
|
2013-01-10 |
2018-12-21 |
思齐乐 |
流感病毒免疫原性组合物及其应用
|
|
US9504747B2
(en)
*
|
2013-03-08 |
2016-11-29 |
Novartis Ag |
Lipids and lipid compositions for the delivery of active agents
|
|
WO2014152211A1
(en)
|
2013-03-14 |
2014-09-25 |
Moderna Therapeutics, Inc. |
Formulation and delivery of modified nucleoside, nucleotide, and nucleic acid compositions
|
|
US20160032316A1
(en)
|
2013-03-14 |
2016-02-04 |
The Trustees Of The University Of Pennsylvania |
Purification and Purity Assessment of RNA Molecules Synthesized with Modified Nucleosides
|
|
US8980864B2
(en)
|
2013-03-15 |
2015-03-17 |
Moderna Therapeutics, Inc. |
Compositions and methods of altering cholesterol levels
|
|
EP3083556B1
(en)
|
2013-12-19 |
2019-12-25 |
Novartis AG |
Lipids and lipid compositions for the delivery of active agents
|
|
JP6948313B6
(ja)
|
2015-09-17 |
2022-01-14 |
モデルナティエックス インコーポレイテッド |
治療剤の細胞内送達のための化合物および組成物
|
|
HRP20230209T1
(hr)
|
2015-10-28 |
2023-04-14 |
Acuitas Therapeutics Inc. |
Novi lipidi i lipidne formulacije nanočestica za isporuku nukleinskih kiselina
|
|
CA3043033A1
(en)
|
2016-11-10 |
2018-05-17 |
Translate Bio, Inc. |
Improved ice-based lipid nanoparticle formulation for delivery of mrna
|
|
WO2018170270A1
(en)
|
2017-03-15 |
2018-09-20 |
Modernatx, Inc. |
Varicella zoster virus (vzv) vaccine
|
|
WO2020106946A1
(en)
|
2018-11-21 |
2020-05-28 |
Translate Bio, Inc. |
TREATMENT OF CYSTIC FIBROSIS BY DELIVERY OF NEBULIZED mRNA ENCODING CFTR
|
|
EP4021407A1
(en)
|
2019-08-30 |
2022-07-06 |
GlaxoSmithKline Biologicals S.A. |
Jet mixing lipid nanoparticle manufacturing process
|
|
DE102019214469A1
(de)
|
2019-09-23 |
2021-03-25 |
Henkel Ag & Co. Kgaa |
Kit und Verfahren zum Färben von keratinischem Material mit Aminosilikon und farbgebender Verbindung
|
|
US11918643B2
(en)
|
2020-12-22 |
2024-03-05 |
CureVac SE |
RNA vaccine against SARS-CoV-2 variants
|