JP2014504865A5 - - Google Patents

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Publication number
JP2014504865A5
JP2014504865A5 JP2013547842A JP2013547842A JP2014504865A5 JP 2014504865 A5 JP2014504865 A5 JP 2014504865A5 JP 2013547842 A JP2013547842 A JP 2013547842A JP 2013547842 A JP2013547842 A JP 2013547842A JP 2014504865 A5 JP2014504865 A5 JP 2014504865A5
Authority
JP
Japan
Prior art keywords
nucleic acid
acid molecule
reference nucleic
binding
level
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2013547842A
Other languages
English (en)
Japanese (ja)
Other versions
JP2014504865A (ja
Filing date
Publication date
Priority claimed from PCT/EP2011/002068 external-priority patent/WO2011131371A1/en
Application filed filed Critical
Priority claimed from PCT/EP2012/000089 external-priority patent/WO2012095303A1/en
Publication of JP2014504865A publication Critical patent/JP2014504865A/ja
Publication of JP2014504865A5 publication Critical patent/JP2014504865A5/ja
Pending legal-status Critical Current

Links

JP2013547842A 2011-01-10 2012-01-10 標的分子との結合親和性を有する核酸分子およびその生成方法 Pending JP2014504865A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
EP11000117.9 2011-01-10
EP11000117 2011-01-10
PCT/EP2011/002068 WO2011131371A1 (en) 2010-04-21 2011-04-21 Lipid binding nucleic acids
EPPCT/EP2011/002068 2011-04-21
EP11008467 2011-10-21
EP11008467.0 2011-10-21
PCT/EP2012/000089 WO2012095303A1 (en) 2011-01-10 2012-01-10 Nucleic acid molecule having binding affinity to a target molecule and a method for generating the same

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017075557A Division JP2017148055A (ja) 2011-01-10 2017-04-05 標的分子との結合親和性を有する核酸分子およびその生成方法

Publications (2)

Publication Number Publication Date
JP2014504865A JP2014504865A (ja) 2014-02-27
JP2014504865A5 true JP2014504865A5 (enExample) 2015-03-05

Family

ID=45464586

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2013547842A Pending JP2014504865A (ja) 2011-01-10 2012-01-10 標的分子との結合親和性を有する核酸分子およびその生成方法
JP2017075557A Pending JP2017148055A (ja) 2011-01-10 2017-04-05 標的分子との結合親和性を有する核酸分子およびその生成方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2017075557A Pending JP2017148055A (ja) 2011-01-10 2017-04-05 標的分子との結合親和性を有する核酸分子およびその生成方法

Country Status (8)

Country Link
US (2) US9976145B2 (enExample)
EP (1) EP2663640B1 (enExample)
JP (2) JP2014504865A (enExample)
KR (2) KR102080142B1 (enExample)
CN (1) CN103339258A (enExample)
AU (1) AU2012206750A1 (enExample)
CA (1) CA2824073A1 (enExample)
WO (1) WO2012095303A1 (enExample)

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SG11201401362TA (en) * 2011-10-21 2014-05-29 Noxxon Pharma Ag Glucagon binding nucleic acids
PT2802660T (pt) 2012-01-10 2020-04-21 Aptarion Biotech Ag Novos ácidos nucleicos que se ligam a c5a
EP2802659A1 (en) * 2012-01-10 2014-11-19 Noxxon Pharma AG Nucleic acids specifically binding cgrp
JP2021523454A (ja) 2018-05-17 2021-09-02 ザ プロクター アンド ギャンブル カンパニーThe Procter & Gamble Company 毛髪分析のためのシステム及び方法
MX2020012225A (es) 2018-05-17 2021-01-29 Procter & Gamble Sistemas y metodos para el analisis de la cobertura del cabello.
WO2020005326A1 (en) 2018-06-29 2020-01-02 The Procter & Gamble Company Aptamers for personal care applications
EP3956451A1 (en) 2019-04-16 2022-02-23 The Procter & Gamble Company Aptamers for odor control applications
US12039732B2 (en) 2021-04-14 2024-07-16 The Procter & Gamble Company Digital imaging and learning systems and methods for analyzing pixel data of a scalp region of a users scalp to generate one or more user-specific scalp classifications
EP4306640A1 (en) 2022-06-21 2024-01-17 TME Pharma AG Method for treating a tumor in a subject
AU2023287476A1 (en) 2022-06-21 2024-12-05 TME Pharma AG Methods for treating a tumor in a subject
WO2026163091A1 (en) 2025-01-29 2026-08-06 ENEA - Agenzia nazionale per le nuove tecnologie, l'energia e lo sviluppo economico sostenibile Stage-specific combined fecal microrna panels as biomarkers for early diagnosis, clinical stratification and monitoring of alzheimer's disease

Family Cites Families (23)

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Publication number Priority date Publication date Assignee Title
ATE318832T1 (de) 1990-06-11 2006-03-15 Gilead Sciences Inc Verfahren zur vervendung von nukleinsäureliganden
US6011020A (en) 1990-06-11 2000-01-04 Nexstar Pharmaceuticals, Inc. Nucleic acid ligand complexes
ES2188985T3 (es) 1996-08-30 2003-07-01 Jens Peter Furste Seleccion enantiomerica y evolucion enantiomerica de acidos nucleicos.
US6395029B1 (en) 1999-01-19 2002-05-28 The Children's Hospital Of Philadelphia Sustained delivery of polyionic bioactive agents
US6652886B2 (en) 2001-02-16 2003-11-25 Expression Genetics Biodegradable cationic copolymers of poly (alkylenimine) and poly (ethylene glycol) for the delivery of bioactive agents
ATE452655T1 (de) 2001-06-10 2010-01-15 Noxxon Pharma Ag Verwendung von l-polynukleotiden zur diagnostischen bilderzeugung
EP1438321B1 (de) 2001-10-26 2010-05-26 Noxxon Pharma AG Modifizierte l-nukleinsäure
EP1306382A1 (de) 2001-10-26 2003-05-02 Noxxon Pharma AG Modifizierte L-Nukleinsäure
WO2003070823A2 (en) 2002-02-20 2003-08-28 The General Hospital Corporation Conjugates comprising a biodegradable polymer and uses therefor
AU2004230927B9 (en) 2003-04-13 2011-12-01 Enzon Pharmaceuticals, Inc. Polymeric oligonucleotide prodrugs
GB0314472D0 (en) 2003-06-20 2003-07-23 Warwick Effect Polymers Ltd Polymer
AU2004291656A1 (en) * 2003-11-10 2005-06-02 Noxxon Pharma Ag Nucleic acids specifically binding bioactive ghrelin
KR101189555B1 (ko) 2004-02-09 2012-10-16 주프라몰 파렌테랄 콜로이츠 게엠베하 폴리사카라이드 및 폴리뉴클레오티드로부터 접합체를제조하는 방법
CA2786794C (en) 2004-03-23 2017-09-12 Complex Biosystems Gmbh Aromatic polymeric cascade prodrug linker reagent
US7579450B2 (en) 2004-04-26 2009-08-25 Archemix Corp. Nucleic acid ligands specific to immunoglobulin E and their use as atopic disease therapeutics
EP1807092B1 (en) 2004-11-05 2016-09-07 The Children's Hospital of Philadelphia Biodegradable linkers for molecular therapies
US20090075342A1 (en) 2005-04-26 2009-03-19 Sharon Cload Metabolic profile directed aptamer medicinal chemistry
DK1948822T3 (da) * 2005-10-07 2011-10-17 Johnson & Johnson Res Pty Ltd Multikomponent-nukleinsyreenzymer og fremgangsmåder til deres anvendelse
US20120101267A1 (en) 2005-10-07 2012-04-26 Alison Velyian Todd Multicomponent nucleic acid enzymes with cleavage, ligase or other activity and methods for their use
WO2008034122A2 (en) 2006-09-15 2008-03-20 Enzon Pharmaceuticals, Inc. Hindered ester-based biodegradable linkers for oligonucleotide delivery
WO2008122084A1 (en) 2007-04-05 2008-10-16 Johnson & Johnson Research Pty Limited Nucleic acid enzymes and complexes and methods for their use
EP2318425A2 (en) * 2008-07-28 2011-05-11 Idera Pharmaceuticals, Inc. Modulation of toll-like receptor 9 expression by antisense oligonucleotides
US8871920B2 (en) 2010-04-21 2014-10-28 Noxxon Pharma Ag Lipid binding nucleic acids

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