JP2014504865A5 - - Google Patents
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- Publication number
- JP2014504865A5 JP2014504865A5 JP2013547842A JP2013547842A JP2014504865A5 JP 2014504865 A5 JP2014504865 A5 JP 2014504865A5 JP 2013547842 A JP2013547842 A JP 2013547842A JP 2013547842 A JP2013547842 A JP 2013547842A JP 2014504865 A5 JP2014504865 A5 JP 2014504865A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- acid molecule
- reference nucleic
- binding
- level
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108020004707 nucleic acids Proteins 0.000 claims 67
- 150000007523 nucleic acids Chemical class 0.000 claims 67
- 102000039446 nucleic acids Human genes 0.000 claims 67
- 125000003729 nucleotide group Chemical group 0.000 claims 36
- 239000002773 nucleotide Substances 0.000 claims 32
- 238000000034 method Methods 0.000 claims 18
- 108091028664 Ribonucleotide Proteins 0.000 claims 5
- 239000005547 deoxyribonucleotide Substances 0.000 claims 5
- 239000002336 ribonucleotide Substances 0.000 claims 5
- 125000002652 ribonucleotide group Chemical group 0.000 claims 5
- 238000004519 manufacturing process Methods 0.000 claims 4
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 239000005557 antagonist Substances 0.000 claims 1
- 239000000032 diagnostic agent Substances 0.000 claims 1
- 229940039227 diagnostic agent Drugs 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 230000001404 mediated effect Effects 0.000 claims 1
- 238000012986 modification Methods 0.000 claims 1
- 230000004048 modification Effects 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 238000006467 substitution reaction Methods 0.000 claims 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11000117.9 | 2011-01-10 | ||
| EP11000117 | 2011-01-10 | ||
| EPPCT/EP2011/002068 | 2011-04-21 | ||
| PCT/EP2011/002068 WO2011131371A1 (en) | 2010-04-21 | 2011-04-21 | Lipid binding nucleic acids |
| EP11008467.0 | 2011-10-21 | ||
| EP11008467 | 2011-10-21 | ||
| PCT/EP2012/000089 WO2012095303A1 (en) | 2011-01-10 | 2012-01-10 | Nucleic acid molecule having binding affinity to a target molecule and a method for generating the same |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017075557A Division JP2017148055A (ja) | 2011-01-10 | 2017-04-05 | 標的分子との結合親和性を有する核酸分子およびその生成方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014504865A JP2014504865A (ja) | 2014-02-27 |
| JP2014504865A5 true JP2014504865A5 (enExample) | 2015-03-05 |
Family
ID=45464586
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013547842A Pending JP2014504865A (ja) | 2011-01-10 | 2012-01-10 | 標的分子との結合親和性を有する核酸分子およびその生成方法 |
| JP2017075557A Pending JP2017148055A (ja) | 2011-01-10 | 2017-04-05 | 標的分子との結合親和性を有する核酸分子およびその生成方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017075557A Pending JP2017148055A (ja) | 2011-01-10 | 2017-04-05 | 標的分子との結合親和性を有する核酸分子およびその生成方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US9976145B2 (enExample) |
| EP (1) | EP2663640B1 (enExample) |
| JP (2) | JP2014504865A (enExample) |
| KR (2) | KR20140026357A (enExample) |
| CN (1) | CN103339258A (enExample) |
| AU (1) | AU2012206750A1 (enExample) |
| CA (1) | CA2824073A1 (enExample) |
| WO (1) | WO2012095303A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014533098A (ja) * | 2011-10-21 | 2014-12-11 | ノクソン・ファルマ・アクチエンゲゼルシャフト | グルカゴン結合核酸 |
| BR112014016877B1 (pt) | 2012-01-10 | 2022-03-15 | Aptarion Biotech Ag | Molécula de l-ácido nucleico capaz de se ligar a c5a humana, seus usos, bem como composição farmacêutica, complexo, método para a seleção de um antagonista de uma atividade mediada por c5a e kit para a detecção de c5a |
| SG11201403769YA (en) * | 2012-01-10 | 2014-07-30 | Noxxon Pharma Ag | Nucleic acids specifically binding cgrp |
| EP3793427A1 (en) | 2018-05-17 | 2021-03-24 | The Procter & Gamble Company | Systems and methods for hair coverage analysis |
| US11172873B2 (en) | 2018-05-17 | 2021-11-16 | The Procter & Gamble Company | Systems and methods for hair analysis |
| EP3814504A1 (en) | 2018-06-29 | 2021-05-05 | The Procter & Gamble Company | Aptamers for personal care applications |
| US11806419B2 (en) | 2019-04-16 | 2023-11-07 | The Procter & Gamble Company | Aptamers for odor control applications |
| US12039732B2 (en) | 2021-04-14 | 2024-07-16 | The Procter & Gamble Company | Digital imaging and learning systems and methods for analyzing pixel data of a scalp region of a users scalp to generate one or more user-specific scalp classifications |
| EP4306640A1 (en) | 2022-06-21 | 2024-01-17 | TME Pharma AG | Method for treating a tumor in a subject |
| WO2023247651A1 (en) | 2022-06-21 | 2023-12-28 | TME Pharma AG | Methods for treating a tumor in a subject |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6011020A (en) | 1990-06-11 | 2000-01-04 | Nexstar Pharmaceuticals, Inc. | Nucleic acid ligand complexes |
| KR970002255B1 (ko) | 1990-06-11 | 1997-02-26 | 넥스스타 파아마슈티컬드, 인크. | 핵산 리간드 |
| JP2001504448A (ja) | 1996-08-30 | 2001-04-03 | フュルステ，イェンス，ペーター | 核酸の鏡面対称選択および進化 |
| US6395029B1 (en) | 1999-01-19 | 2002-05-28 | The Children's Hospital Of Philadelphia | Sustained delivery of polyionic bioactive agents |
| US6652886B2 (en) | 2001-02-16 | 2003-11-25 | Expression Genetics | Biodegradable cationic copolymers of poly (alkylenimine) and poly (ethylene glycol) for the delivery of bioactive agents |
| DK1264603T3 (da) * | 2001-06-10 | 2010-04-26 | Noxxon Pharma Ag | Anvendelse af L-polynukleotider til in vivo-billeddannelse |
| EP1306382A1 (de) | 2001-10-26 | 2003-05-02 | Noxxon Pharma AG | Modifizierte L-Nukleinsäure |
| ES2346640T4 (es) | 2001-10-26 | 2011-04-26 | Noxxon Pharma Ag | Ácido l-nucleico modificado. |
| EP2138575B8 (en) | 2002-02-20 | 2013-07-24 | Mersana Therapeutics, Inc. | Conjugates comprising a biodegradable polymer and uses therefor |
| KR20060015505A (ko) | 2003-04-13 | 2006-02-17 | 엔존 파마슈티컬즈, 인코포레이티드 | 올리고뉴클레오타이드 전구약물 |
| GB0314472D0 (en) | 2003-06-20 | 2003-07-23 | Warwick Effect Polymers Ltd | Polymer |
| AP2006003618A0 (en) | 2003-11-10 | 2006-06-30 | Noxxon Pharma Ag | Nucleic acids specifically binding bioactive ghrelin |
| US20090281296A1 (en) | 2004-02-09 | 2009-11-12 | Supramol Parenteral Colloid Gmbh | Process for the production of conjugates from polysaccharides and polynucelotides |
| ES2741524T3 (es) | 2004-03-23 | 2020-02-11 | Ascendis Pharma Gmbh | Profármaco polimérico con un enlazador autoinmolador |
| US7579450B2 (en) | 2004-04-26 | 2009-08-25 | Archemix Corp. | Nucleic acid ligands specific to immunoglobulin E and their use as atopic disease therapeutics |
| WO2006052790A2 (en) | 2004-11-05 | 2006-05-18 | The Children's Hospital Of Philadelphia | Biodegradable linkers for molecular therapies |
| EP1948822B1 (en) * | 2005-10-07 | 2011-07-13 | Johnson & Johnson Research Pty Limited | Multicomponent nucleic acid enzymes and methods for their use |
| US20120101267A1 (en) | 2005-10-07 | 2012-04-26 | Alison Velyian Todd | Multicomponent nucleic acid enzymes with cleavage, ligase or other activity and methods for their use |
| CN101534643A (zh) | 2006-09-15 | 2009-09-16 | 安佐制药股份有限公司 | 用于递送寡核苷酸的基于位阻酯的生物可降解连接体 |
| WO2008122084A1 (en) | 2007-04-05 | 2008-10-16 | Johnson & Johnson Research Pty Limited | Nucleic acid enzymes and complexes and methods for their use |
| WO2008134077A1 (en) * | 2007-04-30 | 2008-11-06 | Archemix Corp. | Metabolic profile directed aptamer medicinal chemistry |
| MX2011001050A (es) * | 2008-07-28 | 2011-03-15 | Idera Pharmaceuticals Inc | Modulacion de la expresion del receptor 9 tipo larga distancia por oligonucleotidos antisentido. |
| WO2011131371A1 (en) * | 2010-04-21 | 2011-10-27 | Noxxon Pharma Ag | Lipid binding nucleic acids |
-
2012
- 2012-01-10 KR KR1020137017897A patent/KR20140026357A/ko not_active Ceased
- 2012-01-10 WO PCT/EP2012/000089 patent/WO2012095303A1/en not_active Ceased
- 2012-01-10 CA CA2824073A patent/CA2824073A1/en not_active Abandoned
- 2012-01-10 EP EP12700093.3A patent/EP2663640B1/en active Active
- 2012-01-10 AU AU2012206750A patent/AU2012206750A1/en not_active Abandoned
- 2012-01-10 KR KR1020197016125A patent/KR102080142B1/ko active Active
- 2012-01-10 US US13/978,804 patent/US9976145B2/en active Active
- 2012-01-10 CN CN201280007720XA patent/CN103339258A/zh active Pending
- 2012-01-10 JP JP2013547842A patent/JP2014504865A/ja active Pending
-
2017
- 2017-04-05 JP JP2017075557A patent/JP2017148055A/ja active Pending
-
2018
- 2018-05-21 US US15/985,626 patent/US20190367921A1/en not_active Abandoned
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