JP2014148535A5 - - Google Patents
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- JP2014148535A5 JP2014148535A5 JP2014091125A JP2014091125A JP2014148535A5 JP 2014148535 A5 JP2014148535 A5 JP 2014148535A5 JP 2014091125 A JP2014091125 A JP 2014091125A JP 2014091125 A JP2014091125 A JP 2014091125A JP 2014148535 A5 JP2014148535 A5 JP 2014148535A5
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- Prior art keywords
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- cytarabine
- pharmaceutical composition
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55357804P | 2004-03-15 | 2004-03-15 | |
| US60/553,578 | 2004-03-15 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012036919A Division JP2012140442A (ja) | 2004-03-15 | 2012-02-23 | Sns−595、及びその使用方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015140309A Division JP6352863B2 (ja) | 2004-03-15 | 2015-07-14 | Sns−595、及びその使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014148535A JP2014148535A (ja) | 2014-08-21 |
| JP2014148535A5 true JP2014148535A5 (enExample) | 2015-03-19 |
| JP5856644B2 JP5856644B2 (ja) | 2016-02-10 |
Family
ID=34993432
Family Applications (9)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007503987A Expired - Fee Related JP5317472B2 (ja) | 2004-03-15 | 2005-03-14 | Sns−595、及びその使用方法 |
| JP2007503972A Expired - Fee Related JP5096913B2 (ja) | 2004-03-15 | 2005-03-14 | Sns−595、及びその使用方法 |
| JP2011135675A Pending JP2011225590A (ja) | 2004-03-15 | 2011-06-17 | Sns−595、及びその使用方法 |
| JP2012036919A Pending JP2012140442A (ja) | 2004-03-15 | 2012-02-23 | Sns−595、及びその使用方法 |
| JP2014091125A Expired - Fee Related JP5856644B2 (ja) | 2004-03-15 | 2014-04-25 | Sns−595、及びその使用方法 |
| JP2014180862A Expired - Fee Related JP6261477B2 (ja) | 2004-03-15 | 2014-09-05 | Sns−595、及びその使用方法 |
| JP2015140309A Expired - Fee Related JP6352863B2 (ja) | 2004-03-15 | 2015-07-14 | Sns−595、及びその使用方法 |
| JP2016248041A Pending JP2017095471A (ja) | 2004-03-15 | 2016-12-21 | Sns−595、及びその使用方法 |
| JP2018038834A Pending JP2018119977A (ja) | 2004-03-15 | 2018-03-05 | Sns−595、及びその使用方法 |
Family Applications Before (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007503987A Expired - Fee Related JP5317472B2 (ja) | 2004-03-15 | 2005-03-14 | Sns−595、及びその使用方法 |
| JP2007503972A Expired - Fee Related JP5096913B2 (ja) | 2004-03-15 | 2005-03-14 | Sns−595、及びその使用方法 |
| JP2011135675A Pending JP2011225590A (ja) | 2004-03-15 | 2011-06-17 | Sns−595、及びその使用方法 |
| JP2012036919A Pending JP2012140442A (ja) | 2004-03-15 | 2012-02-23 | Sns−595、及びその使用方法 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014180862A Expired - Fee Related JP6261477B2 (ja) | 2004-03-15 | 2014-09-05 | Sns−595、及びその使用方法 |
| JP2015140309A Expired - Fee Related JP6352863B2 (ja) | 2004-03-15 | 2015-07-14 | Sns−595、及びその使用方法 |
| JP2016248041A Pending JP2017095471A (ja) | 2004-03-15 | 2016-12-21 | Sns−595、及びその使用方法 |
| JP2018038834A Pending JP2018119977A (ja) | 2004-03-15 | 2018-03-05 | Sns−595、及びその使用方法 |
Country Status (23)
| Country | Link |
|---|---|
| US (12) | US7968565B2 (enExample) |
| EP (4) | EP1725233B1 (enExample) |
| JP (9) | JP5317472B2 (enExample) |
| KR (1) | KR101169825B1 (enExample) |
| CN (5) | CN103251589B (enExample) |
| AT (2) | ATE493982T1 (enExample) |
| AU (3) | AU2005222622B2 (enExample) |
| BR (1) | BRPI0508700A (enExample) |
| CA (3) | CA2954578A1 (enExample) |
| CY (2) | CY1109741T1 (enExample) |
| DE (2) | DE602005025738D1 (enExample) |
| DK (3) | DK1725233T3 (enExample) |
| ES (3) | ES2334802T3 (enExample) |
| HU (1) | HUE027266T2 (enExample) |
| IL (2) | IL177946A (enExample) |
| MX (2) | MX349188B (enExample) |
| NO (3) | NO338058B1 (enExample) |
| NZ (2) | NZ549557A (enExample) |
| PL (3) | PL1729770T3 (enExample) |
| PT (2) | PT1729770E (enExample) |
| SI (2) | SI1729770T1 (enExample) |
| WO (2) | WO2005089756A1 (enExample) |
| ZA (1) | ZA200607248B (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX349188B (es) | 2004-03-15 | 2017-07-17 | Sunesis Pharmaceuticals Inc | Sns - 595 y metodos para utilizar el mismo. |
| US7652134B2 (en) * | 2004-09-17 | 2010-01-26 | Cylene Pharmaceuticals, Inc. | Methods for converting quinolone esters into quinolone amides |
| BRPI0515319A (pt) * | 2004-09-17 | 2008-07-22 | Cylene Pharmaceuticals Inc | análogos de quinolona |
| US20070117770A1 (en) * | 2005-08-19 | 2007-05-24 | Cylene Pharmaceuticals, Inc. | Human ribosomal DNA (rDNA) and ribosomal RNA (rRNA) nucleic acids and uses thereof |
| JP5374153B2 (ja) * | 2005-09-02 | 2013-12-25 | サネシス ファーマシューティカルズ, インコーポレイテッド | 癌の治療のための(+)−1,4−ジヒドロ−7−[(3s,4s)−3−メトキシ−4−(メチルアミノ)−1−ピロリジニル]−4−オキソ−1−(2−チアゾリル)−1,8−ナフチリジン−3−カルボン酸を使用する方法 |
| AU2006287149B2 (en) * | 2005-09-02 | 2013-05-23 | Sunesis Pharmaceuticals, Inc. | Methods of using (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer |
| US8580814B2 (en) * | 2006-04-03 | 2013-11-12 | Sunesis Pharmaceuticals, Inc. | Methods of using (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4- oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer |
| CA2654876A1 (en) * | 2006-06-12 | 2007-12-21 | Sunesis Pharmaceuticals, Inc. | 1-8-naphthyridine compounds for the treatment of cancer |
| US20100048609A1 (en) * | 2006-08-01 | 2010-02-25 | Jacobs Jeffrey W | Pharmaceutical dosage forms for (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid |
| ES2556677T3 (es) * | 2006-08-02 | 2016-01-19 | Sunesis Pharmaceuticals, Inc. | Utilización combinada de ácido (+)-1,4-dihidro-7-[(3S,4S)-3-metoxi-4-(metilamino)-1-pirrolidinil]-4-oxo-1-(2-tiazolil)-1,8-naftiridin-3-carboxílico y citarabina (Ara-C) para el tratamiento de la leucemia |
| US20090093513A1 (en) * | 2007-10-09 | 2009-04-09 | Hamann Mark T | Method to Use Compositions Having Antidepressant Anxiolytic and Other Neurological Activity and Compositions of Matter |
| AU2008317400B2 (en) * | 2007-10-22 | 2014-10-02 | Sunesis Pharmaceuticals, Inc. | Methods of using (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino) -1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3- carboxylic acid in combination therapy |
| AU2014277779B2 (en) * | 2007-10-22 | 2016-05-19 | Sunesis Pharmaceuticals, Inc. | METHODS OF USING (+)-1,4-DIHYDRO-7-[(3s,4s)-3-METHOXY-4-(METHYLAMINO)-1-PYRROLIDINYL]-4-OXO-1-(2-THIAZOLYL)-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACID IN COMBINATION THERAPY |
| EP2249831A2 (en) * | 2007-12-10 | 2010-11-17 | Sunesis Pharmaceuticals, Inc. | Methods of using (+)-1,4-dihydro-7-ý(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl¨-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of antecedent hematologic disorders |
| KR101765956B1 (ko) | 2008-12-31 | 2017-08-07 | 선에시스 파마슈티컬스 인코포레이티드 | (+)-1,4-다이하이드로-7-[(3s,4s)-3-메톡시-4-(메틸아미노)-1-피롤리딘일]-4-옥소-1-(2-티아졸릴)-1,8-나프티리딘-3-카복실산의 제조 방법 |
| CN104688732A (zh) * | 2009-02-27 | 2015-06-10 | 逊尼希思制药公司 | 利用sns-595治疗具有降低的brca2活性的癌症对象的方法 |
| UA110465C2 (en) * | 2009-09-04 | 2016-01-12 | Sunesis Pharmaceutecals Inc | Stable sns-595 composition |
| WO2011056566A2 (en) * | 2009-10-26 | 2011-05-12 | Sunesis Pharmaceuticals, Inc. | Compounds and methods for treatment of cancer |
| EP2819498B1 (en) | 2012-02-27 | 2017-02-15 | AGQ Technological Corporate S.A. | Monitoring and control of soil conditions |
| SMT201800608T1 (it) | 2012-04-24 | 2019-01-11 | Vertex Pharma | Inibitori di dna-pk |
| AU2014244555B2 (en) | 2013-03-12 | 2018-06-28 | Vertex Pharmaceuticals Incorporated | DNA-PK inhibitors |
| WO2014169067A1 (en) * | 2013-04-09 | 2014-10-16 | Merrimack Pharmaceuticals, Inc. | Compositions for improving outcomes of liposomal chemotherapy |
| EP3016659A4 (en) * | 2013-07-02 | 2017-03-15 | Eustralis Pharmaceuticals Limited (Trading as Pressura Neuro) | Method for preventing and/or treating chronic traumatic encephalopathy-iii |
| HUE041877T2 (hu) | 2013-10-17 | 2019-06-28 | Vertex Pharma | (S)-N-Metil-8-(1-((2'-metil-[4,5'-bipirimidin]-6-il)amino)propán-2-il)kinolin-4-karboxamid kokristályai és deuterált származékai DNS-PK inhibitorokként |
| KR101775356B1 (ko) * | 2015-07-06 | 2017-09-06 | 재단법인 아산사회복지재단 | Parp 및 탄키라제 동시 저해제에 대한 감수성 결정 방법 |
| US11110108B2 (en) | 2016-09-27 | 2021-09-07 | Vertex Pharmaceuticals Incorporated | Method for treating cancer using a combination of DNA-damaging agents and DNA-PK inhibitors |
| WO2025033367A1 (ja) * | 2023-08-04 | 2025-02-13 | 湧永製薬株式会社 | 抗腫瘍剤併用療法 |
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| US5078996A (en) * | 1985-08-16 | 1992-01-07 | Immunex Corporation | Activation of macrophage tumoricidal activity by granulocyte-macrophage colony stimulating factor |
| BR9508037A (pt) | 1994-06-14 | 1997-09-16 | Dainippon Pharmaceutical Co | Derivados de piridona-ácido carboxilico agente anti-tumor composição farmacológica e processo para preparar derivados de piridona-ácido carboxilico |
| JP4323574B2 (ja) | 1995-12-13 | 2009-09-02 | 大日本住友製薬株式会社 | 抗腫瘍剤 |
| GB2322193B (en) * | 1997-01-13 | 1999-09-29 | Cancer Res Campaign Tech | Assays,agents,therapy and diagnosis relating to modulation of cellular dna repair activity |
| US20020032216A1 (en) * | 1997-03-21 | 2002-03-14 | Lg Chemical Ltd. | Salt of naphthyridine carboxylic acid derivative |
| WO1998055615A1 (en) * | 1997-06-05 | 1998-12-10 | The University Of Texas Board Or Regents | Apaf-1, the ced-4 human homolog, an activator of caspase-3 |
| US6171857B1 (en) * | 1997-10-17 | 2001-01-09 | Brown University Research Foundatiion | Leucine zipper protein, KARP-1 and methods of regulating DNA dependent protein kinase activity |
| US5968921A (en) | 1997-10-24 | 1999-10-19 | Orgegon Health Sciences University | Compositions and methods for promoting nerve regeneration |
| IL124015A0 (en) * | 1998-04-08 | 1999-01-26 | Yeda Res & Dev | Pharmaceutical compositions comprising a protein |
| JP4294121B2 (ja) | 1998-06-05 | 2009-07-08 | 大日本住友製薬株式会社 | ピリドンカルボン酸誘導体の製造方法およびその中間体 |
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| MX349188B (es) * | 2004-03-15 | 2017-07-17 | Sunesis Pharmaceuticals Inc | Sns - 595 y metodos para utilizar el mismo. |
| AU2006287149B2 (en) | 2005-09-02 | 2013-05-23 | Sunesis Pharmaceuticals, Inc. | Methods of using (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer |
| US8580814B2 (en) | 2006-04-03 | 2013-11-12 | Sunesis Pharmaceuticals, Inc. | Methods of using (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4- oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer |
| CA2654876A1 (en) | 2006-06-12 | 2007-12-21 | Sunesis Pharmaceuticals, Inc. | 1-8-naphthyridine compounds for the treatment of cancer |
| US20100048609A1 (en) | 2006-08-01 | 2010-02-25 | Jacobs Jeffrey W | Pharmaceutical dosage forms for (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid |
| ES2556677T3 (es) | 2006-08-02 | 2016-01-19 | Sunesis Pharmaceuticals, Inc. | Utilización combinada de ácido (+)-1,4-dihidro-7-[(3S,4S)-3-metoxi-4-(metilamino)-1-pirrolidinil]-4-oxo-1-(2-tiazolil)-1,8-naftiridin-3-carboxílico y citarabina (Ara-C) para el tratamiento de la leucemia |
| AU2008317400B2 (en) | 2007-10-22 | 2014-10-02 | Sunesis Pharmaceuticals, Inc. | Methods of using (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino) -1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3- carboxylic acid in combination therapy |
| EP2249831A2 (en) | 2007-12-10 | 2010-11-17 | Sunesis Pharmaceuticals, Inc. | Methods of using (+)-1,4-dihydro-7-ý(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl¨-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of antecedent hematologic disorders |
| KR101765956B1 (ko) | 2008-12-31 | 2017-08-07 | 선에시스 파마슈티컬스 인코포레이티드 | (+)-1,4-다이하이드로-7-[(3s,4s)-3-메톡시-4-(메틸아미노)-1-피롤리딘일]-4-옥소-1-(2-티아졸릴)-1,8-나프티리딘-3-카복실산의 제조 방법 |
| CN104688732A (zh) | 2009-02-27 | 2015-06-10 | 逊尼希思制药公司 | 利用sns-595治疗具有降低的brca2活性的癌症对象的方法 |
| CN101631081B (zh) | 2009-08-12 | 2011-06-08 | 华为技术有限公司 | 一种多级交换网 |
| UA110465C2 (en) * | 2009-09-04 | 2016-01-12 | Sunesis Pharmaceutecals Inc | Stable sns-595 composition |
| WO2011056566A2 (en) | 2009-10-26 | 2011-05-12 | Sunesis Pharmaceuticals, Inc. | Compounds and methods for treatment of cancer |
-
2005
- 2005-03-14 MX MX2011011851A patent/MX349188B/es unknown
- 2005-03-14 CN CN201210307785.8A patent/CN103251589B/zh not_active Expired - Fee Related
- 2005-03-14 JP JP2007503987A patent/JP5317472B2/ja not_active Expired - Fee Related
- 2005-03-14 EP EP05731600A patent/EP1725233B1/en not_active Expired - Lifetime
- 2005-03-14 EP EP05732554A patent/EP1729770B1/en not_active Expired - Lifetime
- 2005-03-14 PL PL05732554T patent/PL1729770T3/pl unknown
- 2005-03-14 PL PL10177951T patent/PL2295056T3/pl unknown
- 2005-03-14 CN CN200910221540A patent/CN101703508A/zh active Pending
- 2005-03-14 PT PT05732554T patent/PT1729770E/pt unknown
- 2005-03-14 ZA ZA200607248A patent/ZA200607248B/xx unknown
- 2005-03-14 CA CA2954578A patent/CA2954578A1/en not_active Abandoned
- 2005-03-14 CN CN201410477839.4A patent/CN104324029A/zh active Pending
- 2005-03-14 EP EP15202939.3A patent/EP3053579A1/en not_active Withdrawn
- 2005-03-14 JP JP2007503972A patent/JP5096913B2/ja not_active Expired - Fee Related
- 2005-03-14 ES ES05732554T patent/ES2334802T3/es not_active Expired - Lifetime
- 2005-03-14 ES ES10177951.0T patent/ES2566973T3/es not_active Expired - Lifetime
- 2005-03-14 US US11/080,102 patent/US7968565B2/en not_active Expired - Fee Related
- 2005-03-14 EP EP10177951.0A patent/EP2295056B9/en not_active Expired - Lifetime
- 2005-03-14 DK DK05731600.2T patent/DK1725233T3/da active
- 2005-03-14 AT AT05731600T patent/ATE493982T1/de active
- 2005-03-14 KR KR1020067021270A patent/KR101169825B1/ko not_active Expired - Fee Related
- 2005-03-14 DE DE602005025738T patent/DE602005025738D1/de not_active Expired - Lifetime
- 2005-03-14 AT AT05732554T patent/ATE451924T1/de active
- 2005-03-14 AU AU2005222622A patent/AU2005222622B2/en not_active Ceased
- 2005-03-14 CN CN201210307920.9A patent/CN103083316B/zh not_active Expired - Fee Related
- 2005-03-14 CA CA2559650A patent/CA2559650C/en not_active Expired - Fee Related
- 2005-03-14 NZ NZ549557A patent/NZ549557A/en not_active IP Right Cessation
- 2005-03-14 SI SI200530890T patent/SI1729770T1/sl unknown
- 2005-03-14 PL PL05731600T patent/PL1725233T3/pl unknown
- 2005-03-14 US US11/080,283 patent/US7989468B2/en not_active Expired - Fee Related
- 2005-03-14 MX MXPA06010382A patent/MXPA06010382A/es active IP Right Grant
- 2005-03-14 DE DE602005018333T patent/DE602005018333D1/de not_active Expired - Lifetime
- 2005-03-14 DK DK05732554.0T patent/DK1729770T3/da active
- 2005-03-14 HU HUE10177951A patent/HUE027266T2/en unknown
- 2005-03-14 BR BRPI0508700-7A patent/BRPI0508700A/pt not_active IP Right Cessation
- 2005-03-14 CA CA2559652A patent/CA2559652C/en not_active Expired - Fee Related
- 2005-03-14 SI SI200531244T patent/SI1725233T1/sl unknown
- 2005-03-14 DK DK10177951.0T patent/DK2295056T5/en active
- 2005-03-14 ES ES05731600T patent/ES2358267T3/es not_active Expired - Lifetime
- 2005-03-14 CN CN200580015456.4A patent/CN1997368B/zh not_active Expired - Fee Related
- 2005-03-14 PT PT05731600T patent/PT1725233E/pt unknown
- 2005-03-14 WO PCT/US2005/008036 patent/WO2005089756A1/en not_active Ceased
- 2005-03-14 AU AU2005222607A patent/AU2005222607B2/en not_active Ceased
- 2005-03-14 WO PCT/US2005/008346 patent/WO2005089757A1/en not_active Ceased
- 2005-04-14 NZ NZ588060A patent/NZ588060A/en not_active IP Right Cessation
- 2005-09-02 US US11/218,653 patent/US20060063795A1/en active Pending
- 2005-09-02 US US11/218,387 patent/US20060025437A1/en active Pending
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2006
- 2006-06-29 US US11/478,765 patent/US7829577B2/en not_active Expired - Fee Related
- 2006-09-07 IL IL177946A patent/IL177946A/en not_active IP Right Cessation
- 2006-10-12 NO NO20064647A patent/NO338058B1/no not_active IP Right Cessation
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2010
- 2010-01-21 CY CY20101100063T patent/CY1109741T1/el unknown
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2011
- 2011-02-03 CY CY20111100114T patent/CY1111263T1/el unknown
- 2011-03-22 AU AU2011201277A patent/AU2011201277B2/en not_active Ceased
- 2011-04-27 US US13/095,111 patent/US20110263524A1/en not_active Abandoned
- 2011-06-13 US US13/159,258 patent/US8669270B2/en not_active Expired - Fee Related
- 2011-06-17 JP JP2011135675A patent/JP2011225590A/ja active Pending
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2012
- 2012-02-23 JP JP2012036919A patent/JP2012140442A/ja active Pending
-
2013
- 2013-03-11 US US13/794,583 patent/US8822493B2/en not_active Expired - Fee Related
-
2014
- 2014-02-03 US US14/171,673 patent/US20140378505A1/en not_active Abandoned
- 2014-04-25 JP JP2014091125A patent/JP5856644B2/ja not_active Expired - Fee Related
- 2014-08-18 US US14/462,439 patent/US9980949B2/en not_active Expired - Fee Related
- 2014-09-05 JP JP2014180862A patent/JP6261477B2/ja not_active Expired - Fee Related
-
2015
- 2015-04-17 NO NO20150466A patent/NO339613B1/no not_active IP Right Cessation
- 2015-07-14 JP JP2015140309A patent/JP6352863B2/ja not_active Expired - Fee Related
-
2016
- 2016-01-14 US US14/996,025 patent/US9757363B2/en not_active Expired - Fee Related
- 2016-09-26 IL IL248049A patent/IL248049A0/en unknown
- 2016-11-24 NO NO20161867A patent/NO20161867A1/no not_active Application Discontinuation
- 2016-12-21 JP JP2016248041A patent/JP2017095471A/ja active Pending
-
2018
- 2018-03-05 JP JP2018038834A patent/JP2018119977A/ja active Pending
- 2018-04-27 US US15/965,741 patent/US20180316309A1/en not_active Abandoned
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