JP2014141471A - 口腔用組成物 - Google Patents
口腔用組成物 Download PDFInfo
- Publication number
- JP2014141471A JP2014141471A JP2013267437A JP2013267437A JP2014141471A JP 2014141471 A JP2014141471 A JP 2014141471A JP 2013267437 A JP2013267437 A JP 2013267437A JP 2013267437 A JP2013267437 A JP 2013267437A JP 2014141471 A JP2014141471 A JP 2014141471A
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- Prior art keywords
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- composition
- weight
- acid
- oral cavity
- Prior art date
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- Granted
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Abstract
【解決手段】前記課題は、下記(A)及び(B)成分を含む口腔用組成物により解決される:
(A)アミノ酸系アニオン界面活性剤、及び
(B)トウキ、シャクヤク、サリチル酸、サリチル酸の誘導体及びサリチル酸の塩からなる群より選択される少なくとも1種、
を含み、且つ前記(A)成分100重量部に対する前記(B)成分の含有量が0.1〜500重量部である、口腔用組成物。
【選択図】なし
Description
項1.(A)アミノ酸系アニオン界面活性剤、及び
(B)トウキ、シャクヤク、サリチル酸、サリチル酸の誘導体及びサリチル酸の塩からなる群より選択される少なくとも1種
を含み、且つ前記(A)成分100重量部に対する前記(B)成分の含有量が0.1〜500重量部である、口腔用組成物。
項2.前記(A)成分100重量部に対する前記(B)成分の含有量が2〜200重量部である、項1に記載される口腔用組成物。
項3.前記アミノ酸系アニオン界面活性剤が、炭素数8〜18の飽和又は不飽和のアシル基を有する項1又は2に記載される口腔用組成物。
項4.口腔用組成物中に含まれるアニオン界面活性剤の総重量に対する前記アミノ酸系アニオン界面活性剤の割合が50重量%以上である、項1〜3のいずれかに記載される口腔用組成物。
項5.前記(A)成分が、ラウロイルメチルタウリン、ラウロイルメチルタウリンの塩、
ラウロイルグルタミン酸、ラウロイルグルタミン酸の塩、ラウロイルサルコシン、及びラウロイルサルコシンの塩からなる群より選択される少なくとも1種である、項1〜4のいずれかに記載される口腔用組成物。
項6.前記(A)成分がラウロイルメチルタウリン及び/又はその塩である、項1〜5のいずれかに記載される口腔用組成物。
項7.歯磨剤又は洗口剤である、項1〜6のいずれかに記載される口腔用組成物。
本発明の口腔用組成物は(A)アミノ酸系アニオン界面活性剤と、(B)トウキ、シャクヤク、サリチル酸、サリチル酸の誘導体及びサリチル酸の塩からなる群より選択される少なくとも1種とを含み、且つ、前記(A)成分100重量部に対する前記(B)成分の含有量が0.1〜500重量部であることを特徴とする。以下、本発明の口腔用組成物について詳述する。
本発明の口腔用組成物の(A)成分であるアミノ酸系アニオン界面活性剤は、公知のものから適宜選択して使用することができるが、例えば炭素数8〜18、好ましくは炭素数10〜16、より好ましくは10〜14、更に好ましくは12〜14の飽和又は不飽和のアシル基を有するアミノ酸又はタウリンが例示される。アシル基は、アミノ酸又はタウリンのアミノ基と、カルボキシル基とが結合することにより形成される。ここで、アシル基としては、具体的にはオクチル基、デシル基、ラウロイル基、ミリストイル基、パルミトイル基、ステアリル基等が例示される。
本発明の口腔用組成物において(B)成分として、トウキ、シャクヤク、サリチル酸、サリチル酸の誘導体及びサリチル酸の塩からなる群より選択される少なくとも1種が使用される。
げられる。
本発明の口腔用組成物の剤型は、粉末状、液状、ゲル状、顆粒状、錠剤状のいずれであってもよく、口内の清掃、清涼感の付与、殺菌、口臭防止等を目的として口腔内に適用される限り、従来公知の態様から適宜選択することができる。本発明の口腔用組成物の剤型として具体的には、粉歯磨剤、練歯磨剤、ジェル歯磨剤及び液体歯磨剤等の歯磨剤、ならびに洗口剤等が例示される。また、液状の剤型については、原液のまま使用するタイプであってもよく、濃縮タイプであって使用時に希釈して用いるタイプであってもよい。本発明の口腔用組成物の剤型を歯磨剤又は洗口剤とすることにより、口内に適用した場合に口腔粘膜に対する刺激の低減、優れた起泡性をより一層顕著に実感することができることから、これらが本発明における好適な剤型として挙げられる。特に、練歯磨剤及びジェル歯磨剤においては、起泡性と洗浄効果感の相関が強く、起泡性が向上した場合、その差異を敏感に実感することができるため、練歯磨剤及びジェル歯磨剤は、本発明における好適な剤型として挙げられる。
下表1〜10に示される歯磨剤を、原料を室温(約25℃)下において脱気混合することにより調製した。より具体的には、(A)成分、精製水、濃グリセリン、ソルビット液及び無水ケイ酸を10分間攪拌混合した後、別途混合しておいた(B)成分、エタノール及びポリオキシエチレン硬化ヒマシ油を加えて10分間撹拌し、最後にカルボキシメチルセルロースナトリウム及びポリアクリル酸ナトリウムを加えて更に15分撹拌し脱気させた。
発泡量=泡部分の最上部の目盛−液部分(60mL)
下記表11〜17に練歯磨剤の処方例を示す。練歯磨剤の調製は、(A)成分、精製水、濃グリセリン、ソルビット液、無水ケイ酸、グリチルリチン酸ジカリウム、アラントイン、マツエキス、クエン酸ナトリウム、クエン酸を10分間攪拌混合した後、別途混合しておいた(B)成分、エタノール、ポリオキシエチレン硬化ヒマシ油、トコフェロール酢酸エステル及びl−メントールを10分間撹拌し、最後にカルボキシメチルセルロースナトリウム及びポリアクリル酸ナトリウムを加えて更に15分撹拌し脱気させることにより行った。
下表18に液体歯磨剤又は洗口剤の処方例を示す。液体歯磨剤又は洗口剤は、(A)成分、精製水、濃グリセリン、ソルビット液、グリチルリチン酸ジカリウム、アラントイン、マツエキス、クエン酸ナトリウム及びクエン酸を10分間撹拌した後、別途混合しておいた(B)成分、エタノール、トコフェロール酢酸エステル、ポリオキシエチレン硬化ヒマシ油及びL−メントールと共に更に10分間撹拌することにより調製される。
Claims (7)
- (A)アミノ酸系アニオン界面活性剤、及び
(B)トウキ、シャクヤク、サリチル酸、サリチル酸の誘導体及びサリチル酸の塩からなる群より選択される少なくとも1種
を含み、且つ前記(A)成分100重量部に対する前記(B)成分の含有量が0.1〜500重量部である、口腔用組成物。 - 前記(A)成分100重量部に対する前記(B)成分の含有量が2〜200重量部である、請求項1に記載される口腔用組成物。
- 前記アミノ酸系アニオン界面活性剤が、炭素数8〜18の飽和又は不飽和のアシル基を有する請求項1又は2に記載される口腔用組成物。
- 口腔用組成物中に含まれるアニオン界面活性剤の総重量に対する前記アミノ酸系アニオン界面活性剤の割合が50重量%以上である、請求項1〜3のいずれかに記載される口腔用組成物。
- 前記(A)成分が、ラウロイルメチルタウリン、ラウロイルメチルタウリンの塩、ラウロイルグルタミン酸、ラウロイルグルタミン酸の塩、ラウロイルサルコシン、及びラウロイルサルコシンの塩からなる群より選択される少なくとも1種である、請求項1〜4のいずれかに記載される口腔用組成物。
- 前記(A)成分がラウロイルメチルタウリン及び/又はその塩である、請求項1〜5のいずれかに記載される口腔用組成物。
- 歯磨剤又は洗口剤である、請求項1〜6のいずれかに記載される口腔用組成物。
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