JP2013544494A5 - - Google Patents

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Publication number
JP2013544494A5
JP2013544494A5 JP2013527595A JP2013527595A JP2013544494A5 JP 2013544494 A5 JP2013544494 A5 JP 2013544494A5 JP 2013527595 A JP2013527595 A JP 2013527595A JP 2013527595 A JP2013527595 A JP 2013527595A JP 2013544494 A5 JP2013544494 A5 JP 2013544494A5
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JP
Japan
Prior art keywords
seq
cells
ion channel
retinal
photoinduced
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JP2013527595A
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English (en)
Japanese (ja)
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JP2013544494A (ja
JP5933556B2 (ja
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Priority claimed from PCT/EP2011/065510 external-priority patent/WO2012032103A1/en
Publication of JP2013544494A publication Critical patent/JP2013544494A/ja
Publication of JP2013544494A5 publication Critical patent/JP2013544494A5/ja
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Publication of JP5933556B2 publication Critical patent/JP5933556B2/ja
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JP2013527595A 2010-09-08 2011-09-08 変異チャネルロドプシン2 Active JP5933556B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US38079310P 2010-09-08 2010-09-08
US61/380,793 2010-09-08
EP10175832 2010-09-08
EP10175832.4 2010-09-08
PCT/EP2011/065510 WO2012032103A1 (en) 2010-09-08 2011-09-08 Mutant channelrhodopsin 2

Publications (3)

Publication Number Publication Date
JP2013544494A JP2013544494A (ja) 2013-12-19
JP2013544494A5 true JP2013544494A5 (enExample) 2014-10-02
JP5933556B2 JP5933556B2 (ja) 2016-06-15

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ID=42979822

Family Applications (1)

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JP2013527595A Active JP5933556B2 (ja) 2010-09-08 2011-09-08 変異チャネルロドプシン2

Country Status (20)

Country Link
US (1) US8748578B2 (enExample)
EP (1) EP2614079B1 (enExample)
JP (1) JP5933556B2 (enExample)
KR (1) KR101945962B1 (enExample)
CN (1) CN103261219B (enExample)
AU (1) AU2011298745B2 (enExample)
BR (1) BR112013005634A2 (enExample)
CA (1) CA2810757C (enExample)
DK (1) DK2614079T3 (enExample)
ES (1) ES2545992T3 (enExample)
HR (1) HRP20150846T1 (enExample)
HU (1) HUE025952T2 (enExample)
IL (1) IL225060A (enExample)
MX (1) MX347453B (enExample)
PL (1) PL2614079T3 (enExample)
PT (1) PT2614079E (enExample)
RU (1) RU2595384C2 (enExample)
SG (1) SG188409A1 (enExample)
SI (1) SI2614079T1 (enExample)
WO (1) WO2012032103A1 (enExample)

Families Citing this family (51)

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US10052497B2 (en) 2005-07-22 2018-08-21 The Board Of Trustees Of The Leland Stanford Junior University System for optical stimulation of target cells
US20070053996A1 (en) 2005-07-22 2007-03-08 Boyden Edward S Light-activated cation channel and uses thereof
US8926959B2 (en) 2005-07-22 2015-01-06 The Board Of Trustees Of The Leland Stanford Junior University System for optical stimulation of target cells
US9274099B2 (en) 2005-07-22 2016-03-01 The Board Of Trustees Of The Leland Stanford Junior University Screening test drugs to identify their effects on cell membrane voltage-gated ion channel
US9238150B2 (en) 2005-07-22 2016-01-19 The Board Of Trustees Of The Leland Stanford Junior University Optical tissue interface method and apparatus for stimulating cells
US8470790B2 (en) 2006-05-04 2013-06-25 Wayne State University Restoration of visual responses by in vivo delivery of rhodopsin nucleic acids
WO2008086470A1 (en) 2007-01-10 2008-07-17 The Board Of Trustees Of The Leland Stanford Junior University System for optical stimulation of target cells
WO2008101128A1 (en) 2007-02-14 2008-08-21 The Board Of Trustees Of The Leland Stanford Junior University System, method and applications involving identification of biological circuits such as neurological characteristics
WO2008106694A2 (en) 2007-03-01 2008-09-04 The Board Of Trustees Of The Leland Stanford Junior University Systems, methods and compositions for optical stimulation of target cells
US10035027B2 (en) 2007-10-31 2018-07-31 The Board Of Trustees Of The Leland Stanford Junior University Device and method for ultrasonic neuromodulation via stereotactic frame based technique
US10434327B2 (en) 2007-10-31 2019-10-08 The Board Of Trustees Of The Leland Stanford Junior University Implantable optical stimulators
SG189813A1 (en) 2008-04-23 2013-05-31 Univ Leland Stanford Junior Systems, methods and compositions for optical stimulation of target cells
JP5890176B2 (ja) 2008-05-29 2016-03-22 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー セカンドメッセンジャーを光制御するためのセルライン、システム、および方法
AU2009260029B2 (en) 2008-06-17 2016-03-17 The Board Of Trustees Of The Leland Stanford Junior University Methods, systems and devices for optical stimulation of target cells using an optical transmission element
EP2303405A4 (en) 2008-06-17 2017-12-27 The Board of Trustees of the Leland Stanford Junior University Apparatus and methods for controlling cellular development
US9101759B2 (en) 2008-07-08 2015-08-11 The Board Of Trustees Of The Leland Stanford Junior University Materials and approaches for optical stimulation of the peripheral nervous system
NZ602416A (en) 2008-11-14 2014-08-29 Univ Leland Stanford Junior Optically-based stimulation of target cells and modifications thereto
JP5866332B2 (ja) 2010-03-17 2016-02-17 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー 感光性イオンを通過させる分子
US9453241B2 (en) 2010-05-04 2016-09-27 Wayne State University AAV-mediated subcellular targeting of heterologous rhodopsins in retinal ganglion cells
WO2012061681A1 (en) 2010-11-05 2012-05-10 The Board Of Trustees Of The Leland Stanford Junior University. Control and characterization of memory function
CN103491770B (zh) 2010-11-05 2016-06-08 斯坦福大学托管董事会 稳定阶跃函数视蛋白及其使用方法
US9992981B2 (en) 2010-11-05 2018-06-12 The Board Of Trustees Of The Leland Stanford Junior University Optogenetic control of reward-related behaviors
CA2817175C (en) 2010-11-05 2019-09-24 The Board Of Trustees Of The Leland Stanford Junior University Upconversion of light using lanthanide-doped nanoparticles for use in optogenetic methods
EP3486253A1 (en) 2010-11-05 2019-05-22 The Board of Trustees of The Leland Stanford Junior University Light-activated chimeric opsins and methods of using the same
CN106106368A (zh) 2010-11-05 2016-11-16 斯坦福大学托管董事会 光控cns功能障碍
US8696722B2 (en) 2010-11-22 2014-04-15 The Board Of Trustees Of The Leland Stanford Junior University Optogenetic magnetic resonance imaging
EP3524676A1 (en) 2011-12-16 2019-08-14 The Board of Trustees of The Leland Stanford Junior University Opsin polypeptides and methods of use thereof
ES2628006T3 (es) 2012-02-21 2017-08-01 Circuit Therapeutics, Inc. Composiciones para el tratamiento de trastornos neurogénicos del suelo pélvico
CN111378020A (zh) * 2012-03-05 2020-07-07 韦恩州立大学 通道视蛋白-2(Chop2)突变的鉴定及使用方法
US9636380B2 (en) 2013-03-15 2017-05-02 The Board Of Trustees Of The Leland Stanford Junior University Optogenetic control of inputs to the ventral tegmental area
US10974064B2 (en) 2013-03-15 2021-04-13 The Board Of Trustees Of The Leland Stanford Junior University Optogenetic control of behavioral state
WO2014179331A2 (en) 2013-04-29 2014-11-06 The Board Of Trustees Of The Leland Stanford Junior University Devices, systems and methods for optogenetic modulation of action potentials in target cells
CA2921221A1 (en) 2013-08-14 2015-02-19 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for controlling pain
JP6118239B2 (ja) 2013-11-29 2017-04-19 雅敏 堀 害虫の防除方法及び防除装置
EP3102290A1 (en) 2014-02-07 2016-12-14 Massachusetts Institute Of Technology Blue light-activated ion channel molecules and uses thereof
WO2015142984A1 (en) * 2014-03-18 2015-09-24 Washington University Methods and compositions for red-shifted chromophore substitution for optogenetic applications
WO2015161308A1 (en) * 2014-04-18 2015-10-22 Massachusetts Institute Of Technology Mutant channelrhodopsins with altered ion selectivity
WO2016209654A1 (en) 2015-06-22 2016-12-29 The Board Of Trustees Of The Leland Stanford Junior University Methods and devices for imaging and/or optogenetic control of light-responsive neurons
JP2019522469A (ja) * 2016-06-03 2019-08-15 マックス−プランク−ゲゼルシャフト ツア フェルデルンク デア ヴィッセンシャフテン エー.ファウ. チャネルロドプシンの変異型光誘導性イオンチャネル
WO2017207761A1 (en) 2016-06-03 2017-12-07 Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V. Mutant light-inducible ion channel of chrimson
RU2019109021A (ru) 2016-08-29 2020-09-29 Уэйн Стейт Юниверсити Идентификация мутаций в вариантах каналопсина, имеющих улучшенную чувствительность к свету, и способы их применения
WO2018106369A2 (en) 2016-11-06 2018-06-14 Nanoscope Technologies Llc Optogenetic modulation by multi-characteristic opsins for vision restoration and other applications thereof
US11294165B2 (en) 2017-03-30 2022-04-05 The Board Of Trustees Of The Leland Stanford Junior University Modular, electro-optical device for increasing the imaging field of view using time-sequential capture
WO2018189247A1 (en) * 2017-04-12 2018-10-18 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. New optogenetic tool
CN110483645B (zh) * 2018-05-14 2023-05-12 郑州大学第一附属医院 线粒体定位质子泵型视紫红质、其突变蛋白及其应用
GB2586751B (en) * 2018-07-26 2022-12-07 Council Scient Ind Res Screening kit for detection of grades of cervical cancer and process for the preparation thereof
WO2020054868A1 (ja) * 2018-09-14 2020-03-19 国立大学法人名古屋工業大学 光応答性タンパク質及びその利用
JP7723983B2 (ja) * 2020-03-13 2025-08-15 国立大学法人 名古屋工業大学 色認識のための光応答性タンパク質及びその利用
WO2022176754A1 (ja) * 2021-02-18 2022-08-25 国立大学法人名古屋工業大学 青色光もしくは藍色光応答性タンパク質及びその利用
EP4223768A1 (en) 2022-02-04 2023-08-09 Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin Novel mutant bacteriorhodopsin-like-channelrhodopsin ion channel
WO2024092248A1 (en) * 2022-10-28 2024-05-02 The Board Of Trustees Of The Leland Stanford Junior University Enhanced light gated potassium selective channelrhodopsin

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EP2112501A1 (de) 1998-02-05 2009-10-28 Novartis Ag Verfahren und Vorrichtung zur Lumineszenzmessung
DE10216005A1 (de) 2002-04-11 2003-10-30 Max Planck Gesellschaft Verwendung von biologischen Photorezeptoren als direkt lichtgesteuerte Ionenkanäle
US8470790B2 (en) * 2006-05-04 2013-06-25 Wayne State University Restoration of visual responses by in vivo delivery of rhodopsin nucleic acids
DE102008020152B4 (de) * 2008-04-22 2012-04-05 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Verwendung von biologischen Photorezeptoren als direkt lichtgesteuerte Ionenkanäle
NZ602416A (en) * 2008-11-14 2014-08-29 Univ Leland Stanford Junior Optically-based stimulation of target cells and modifications thereto

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