PT2614079E - Canalrodopsina 2 mutante - Google Patents
Canalrodopsina 2 mutante Download PDFInfo
- Publication number
- PT2614079E PT2614079E PT117604322T PT11760432T PT2614079E PT 2614079 E PT2614079 E PT 2614079E PT 117604322 T PT117604322 T PT 117604322T PT 11760432 T PT11760432 T PT 11760432T PT 2614079 E PT2614079 E PT 2614079E
- Authority
- PT
- Portugal
- Prior art keywords
- channelrhodopsin
- mutant
- mutant channelrhodopsin
- Prior art date
Links
- 108010035848 Channelrhodopsins Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/405—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from algae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Toxicology (AREA)
- General Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38079310P | 2010-09-08 | 2010-09-08 | |
| EP10175832 | 2010-09-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2614079E true PT2614079E (pt) | 2015-10-06 |
Family
ID=42979822
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT117604322T PT2614079E (pt) | 2010-09-08 | 2011-09-08 | Canalrodopsina 2 mutante |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US8748578B2 (pt) |
| EP (1) | EP2614079B1 (pt) |
| JP (1) | JP5933556B2 (pt) |
| KR (1) | KR101945962B1 (pt) |
| CN (1) | CN103261219B (pt) |
| AU (1) | AU2011298745B2 (pt) |
| BR (1) | BR112013005634A2 (pt) |
| CA (1) | CA2810757C (pt) |
| DK (1) | DK2614079T3 (pt) |
| ES (1) | ES2545992T3 (pt) |
| HR (1) | HRP20150846T1 (pt) |
| HU (1) | HUE025952T2 (pt) |
| IL (1) | IL225060A (pt) |
| MX (1) | MX347453B (pt) |
| PL (1) | PL2614079T3 (pt) |
| PT (1) | PT2614079E (pt) |
| RU (1) | RU2595384C2 (pt) |
| SG (1) | SG188409A1 (pt) |
| SI (1) | SI2614079T1 (pt) |
| WO (1) | WO2012032103A1 (pt) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8926959B2 (en) | 2005-07-22 | 2015-01-06 | The Board Of Trustees Of The Leland Stanford Junior University | System for optical stimulation of target cells |
| US20090093403A1 (en) | 2007-03-01 | 2009-04-09 | Feng Zhang | Systems, methods and compositions for optical stimulation of target cells |
| US10052497B2 (en) | 2005-07-22 | 2018-08-21 | The Board Of Trustees Of The Leland Stanford Junior University | System for optical stimulation of target cells |
| US9274099B2 (en) | 2005-07-22 | 2016-03-01 | The Board Of Trustees Of The Leland Stanford Junior University | Screening test drugs to identify their effects on cell membrane voltage-gated ion channel |
| US9238150B2 (en) | 2005-07-22 | 2016-01-19 | The Board Of Trustees Of The Leland Stanford Junior University | Optical tissue interface method and apparatus for stimulating cells |
| US8906360B2 (en) | 2005-07-22 | 2014-12-09 | The Board Of Trustees Of The Leland Stanford Junior University | Light-activated cation channel and uses thereof |
| CN101484005A (zh) | 2006-05-04 | 2009-07-15 | 韦恩州立大学 | 通过向体内递送视紫红质核酸恢复视觉响应 |
| US8398692B2 (en) | 2007-01-10 | 2013-03-19 | The Board Of Trustees Of The Leland Stanford Junior University | System for optical stimulation of target cells |
| WO2008101128A1 (en) | 2007-02-14 | 2008-08-21 | The Board Of Trustees Of The Leland Stanford Junior University | System, method and applications involving identification of biological circuits such as neurological characteristics |
| US10035027B2 (en) | 2007-10-31 | 2018-07-31 | The Board Of Trustees Of The Leland Stanford Junior University | Device and method for ultrasonic neuromodulation via stereotactic frame based technique |
| US10434327B2 (en) | 2007-10-31 | 2019-10-08 | The Board Of Trustees Of The Leland Stanford Junior University | Implantable optical stimulators |
| EP2281039B1 (en) | 2008-04-23 | 2016-09-28 | The Board of Trustees of the Leland Stanford Junior University | Systems, methods and compositions for optical stimulation of target cells |
| MY152003A (en) | 2008-05-29 | 2014-08-15 | Univ Leland Stanford Junior | Cell line, system and method for optical control of secondary messengers |
| CA2728402A1 (en) | 2008-06-17 | 2009-12-23 | The Board Of Trustees Of The Leland Stanford Junior University | Apparatus and methods for controlling cellular development |
| EP2303406B1 (en) | 2008-06-17 | 2016-11-09 | The Board of Trustees of the Leland Stanford Junior University | Devices for optical stimulation of target cells using an optical transmission element |
| WO2010006049A1 (en) | 2008-07-08 | 2010-01-14 | The Board Of Trustees Of The Leland Stanford Junior University | Materials and approaches for optical stimulation of the peripheral nervous system |
| NZ602416A (en) | 2008-11-14 | 2014-08-29 | Univ Leland Stanford Junior | Optically-based stimulation of target cells and modifications thereto |
| AU2011227131B2 (en) | 2010-03-17 | 2014-11-13 | The Board Of Trustees Of The Leland Stanford Junior University | Light-sensitive ion-passing molecules |
| US9453241B2 (en) | 2010-05-04 | 2016-09-27 | Wayne State University | AAV-mediated subcellular targeting of heterologous rhodopsins in retinal ganglion cells |
| WO2012061690A2 (en) | 2010-11-05 | 2012-05-10 | The Board Of Trustees Of The Leland Stanford Junior University | Optically-controlled cns dysfunction |
| CN103476456B (zh) | 2010-11-05 | 2017-10-03 | 斯坦福大学托管董事会 | 奖赏相关行为的光遗传学控制 |
| ES2661093T3 (es) | 2010-11-05 | 2018-03-27 | The Board Of Trustees Of The University Of The Leland Stanford Junior University | Control y caracterización de la función de la memoria |
| AU2011323226B2 (en) | 2010-11-05 | 2015-03-12 | The Board Of Trustees Of The Leland Stanford Junior University | Light-activated chimeric opsins and methods of using the same |
| CN105941328B (zh) | 2010-11-05 | 2019-04-09 | 斯坦福大学托管董事会 | 一种鉴定抑制前额叶皮质中的兴奋性或抑制性神经元的去极化的化合物的系统 |
| ES2690172T3 (es) | 2010-11-05 | 2018-11-19 | The Board Of Trustees Of The Leland Stanford Junior University | Conversión ascendente de la luz para su uso en métodos optogenéticos |
| US8696722B2 (en) | 2010-11-22 | 2014-04-15 | The Board Of Trustees Of The Leland Stanford Junior University | Optogenetic magnetic resonance imaging |
| AU2012352429B2 (en) | 2011-12-16 | 2018-07-19 | The Board Of Trustees Of The Leland Stanford Junior University | Opsin polypeptides and methods of use thereof |
| WO2013126521A1 (en) | 2012-02-21 | 2013-08-29 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for treating neurogenic disorders of the pelvic floor |
| ES2703324T3 (es) * | 2012-03-05 | 2019-03-08 | Univ Wayne State | Identificación de mutaciones de canalrodopsina-2 (Chop2) y métodos de uso |
| US9636380B2 (en) | 2013-03-15 | 2017-05-02 | The Board Of Trustees Of The Leland Stanford Junior University | Optogenetic control of inputs to the ventral tegmental area |
| ES2742492T3 (es) | 2013-03-15 | 2020-02-14 | Univ Leland Stanford Junior | Control optogenético del estado conductual |
| US10220092B2 (en) | 2013-04-29 | 2019-03-05 | The Board Of Trustees Of The Leland Stanford Junior University | Devices, systems and methods for optogenetic modulation of action potentials in target cells |
| WO2015023782A1 (en) | 2013-08-14 | 2015-02-19 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for controlling pain |
| JP6118239B2 (ja) * | 2013-11-29 | 2017-04-19 | 雅敏 堀 | 害虫の防除方法及び防除装置 |
| US10392426B2 (en) | 2014-02-07 | 2019-08-27 | Massachusetts Institute Of Technology | Blue-light-activated ion channel polypeptides and uses thereof |
| US10047130B2 (en) | 2014-03-18 | 2018-08-14 | Washington University | Methods and compositions for red-shifted chromophore substitution for optogenetic applications |
| WO2015161308A1 (en) * | 2014-04-18 | 2015-10-22 | Massachusetts Institute Of Technology | Mutant channelrhodopsins with altered ion selectivity |
| US10568516B2 (en) | 2015-06-22 | 2020-02-25 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and devices for imaging and/or optogenetic control of light-responsive neurons |
| WO2017207745A1 (en) | 2016-06-03 | 2017-12-07 | Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V. | Mutant light-inducible ion channel of channelrhodopsin |
| EP3464342A1 (en) * | 2016-06-03 | 2019-04-10 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Mutant light-inducible ion channel of chrimson |
| CN110267972A (zh) | 2016-11-06 | 2019-09-20 | 纳秒示波器科技有限公司 | 由多特征视蛋白进行的用于视力恢复的光学调制以及其其他应用 |
| US11294165B2 (en) | 2017-03-30 | 2022-04-05 | The Board Of Trustees Of The Leland Stanford Junior University | Modular, electro-optical device for increasing the imaging field of view using time-sequential capture |
| CN111032068A (zh) * | 2017-04-12 | 2020-04-17 | 马克斯·普朗克科学促进学会 | 新的光遗传学工具 |
| CN110483645B (zh) * | 2018-05-14 | 2023-05-12 | 郑州大学第一附属医院 | 线粒体定位质子泵型视紫红质、其突变蛋白及其应用 |
| JP7242851B2 (ja) * | 2018-07-26 | 2023-03-20 | カウンシル・オブ・サイエンティフィック・アンド・インダストリアル・リサーチ・アン・インディアン・レジスタード・ボディ・インコーポレイテッド・アンダー・ザ・レジストレーション・オブ・ソサエティーズ・アクト・(アクト・21・オブ・1860) | 子宮頸がんのグレード検出のためのスクリーニングキットおよびその調製方法 |
| WO2020054868A1 (ja) * | 2018-09-14 | 2020-03-19 | 国立大学法人名古屋工業大学 | 光応答性タンパク質及びその利用 |
| CN115397991B (zh) * | 2020-03-13 | 2024-09-20 | 国立大学法人名古屋工业大学 | 用于颜色识别的光响应性蛋白及其应用 |
| WO2022176754A1 (ja) * | 2021-02-18 | 2022-08-25 | 国立大学法人名古屋工業大学 | 青色光もしくは藍色光応答性タンパク質及びその利用 |
| EP4223768A1 (en) | 2022-02-04 | 2023-08-09 | Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin | Novel mutant bacteriorhodopsin-like-channelrhodopsin ion channel |
| WO2024092248A1 (en) * | 2022-10-28 | 2024-05-02 | The Board Of Trustees Of The Leland Stanford Junior University | Enhanced light gated potassium selective channelrhodopsin |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2112501A1 (de) | 1998-02-05 | 2009-10-28 | Novartis Ag | Verfahren und Vorrichtung zur Lumineszenzmessung |
| DE10216005A1 (de) * | 2002-04-11 | 2003-10-30 | Max Planck Gesellschaft | Verwendung von biologischen Photorezeptoren als direkt lichtgesteuerte Ionenkanäle |
| CN101484005A (zh) * | 2006-05-04 | 2009-07-15 | 韦恩州立大学 | 通过向体内递送视紫红质核酸恢复视觉响应 |
| DE102008020152B4 (de) * | 2008-04-22 | 2012-04-05 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Verwendung von biologischen Photorezeptoren als direkt lichtgesteuerte Ionenkanäle |
| NZ602416A (en) * | 2008-11-14 | 2014-08-29 | Univ Leland Stanford Junior | Optically-based stimulation of target cells and modifications thereto |
-
2011
- 2011-09-08 EP EP11760432.2A patent/EP2614079B1/en active Active
- 2011-09-08 KR KR1020137008660A patent/KR101945962B1/ko active IP Right Grant
- 2011-09-08 JP JP2013527595A patent/JP5933556B2/ja active Active
- 2011-09-08 BR BR112013005634A patent/BR112013005634A2/pt not_active Application Discontinuation
- 2011-09-08 PT PT117604322T patent/PT2614079E/pt unknown
- 2011-09-08 CA CA2810757A patent/CA2810757C/en active Active
- 2011-09-08 CN CN201180052156.9A patent/CN103261219B/zh active Active
- 2011-09-08 AU AU2011298745A patent/AU2011298745B2/en active Active
- 2011-09-08 US US13/821,353 patent/US8748578B2/en active Active
- 2011-09-08 DK DK11760432.2T patent/DK2614079T3/en active
- 2011-09-08 ES ES11760432.2T patent/ES2545992T3/es active Active
- 2011-09-08 RU RU2013115454/10A patent/RU2595384C2/ru active
- 2011-09-08 SI SI201130552T patent/SI2614079T1/sl unknown
- 2011-09-08 SG SG2013016332A patent/SG188409A1/en unknown
- 2011-09-08 HU HUE11760432A patent/HUE025952T2/en unknown
- 2011-09-08 WO PCT/EP2011/065510 patent/WO2012032103A1/en active Application Filing
- 2011-09-08 PL PL11760432T patent/PL2614079T3/pl unknown
- 2011-09-08 MX MX2013002591A patent/MX347453B/es active IP Right Grant
-
2013
- 2013-03-05 IL IL225060A patent/IL225060A/en active IP Right Grant
-
2015
- 2015-08-10 HR HRP20150846TT patent/HRP20150846T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR112013005634A2 (pt) | 2017-06-27 |
| SG188409A1 (en) | 2013-04-30 |
| JP2013544494A (ja) | 2013-12-19 |
| JP5933556B2 (ja) | 2016-06-15 |
| ES2545992T3 (es) | 2015-09-17 |
| EP2614079B1 (en) | 2015-07-15 |
| US20130281379A1 (en) | 2013-10-24 |
| CN103261219A (zh) | 2013-08-21 |
| US8748578B2 (en) | 2014-06-10 |
| EP2614079A1 (en) | 2013-07-17 |
| HUE025952T2 (en) | 2016-04-28 |
| KR20130108335A (ko) | 2013-10-02 |
| MX347453B (es) | 2017-04-27 |
| RU2595384C2 (ru) | 2016-08-27 |
| MX2013002591A (es) | 2013-07-22 |
| DK2614079T3 (en) | 2015-08-10 |
| AU2011298745A1 (en) | 2013-03-21 |
| HRP20150846T1 (hr) | 2015-09-11 |
| CA2810757A1 (en) | 2012-03-15 |
| RU2013115454A (ru) | 2014-10-20 |
| IL225060A (en) | 2016-10-31 |
| CN103261219B (zh) | 2017-05-17 |
| CA2810757C (en) | 2020-06-09 |
| KR101945962B1 (ko) | 2019-02-08 |
| AU2011298745B2 (en) | 2015-05-07 |
| PL2614079T3 (pl) | 2016-01-29 |
| WO2012032103A1 (en) | 2012-03-15 |
| SI2614079T1 (sl) | 2015-10-30 |
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