JP2019526270A5 - - Google Patents
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- Publication number
- JP2019526270A5 JP2019526270A5 JP2019513999A JP2019513999A JP2019526270A5 JP 2019526270 A5 JP2019526270 A5 JP 2019526270A5 JP 2019513999 A JP2019513999 A JP 2019513999A JP 2019513999 A JP2019513999 A JP 2019513999A JP 2019526270 A5 JP2019526270 A5 JP 2019526270A5
- Authority
- JP
- Japan
- Prior art keywords
- bcr
- nucleic acid
- acid encoding
- primary
- therapeutic cassette
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 108091008875 B cell receptors Proteins 0.000 claims 6
- 230000001225 therapeutic effect Effects 0.000 claims 5
- 210000003719 b-lymphocyte Anatomy 0.000 claims 4
- 108020004707 nucleic acids Proteins 0.000 claims 4
- 150000007523 nucleic acids Chemical class 0.000 claims 4
- 102000039446 nucleic acids Human genes 0.000 claims 4
- 239000000427 antigen Substances 0.000 claims 2
- 108091007433 antigens Proteins 0.000 claims 2
- 102000036639 antigens Human genes 0.000 claims 2
- 239000003623 enhancer Substances 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 229940123611 Genome editing Drugs 0.000 claims 1
- 238000010362 genome editing Methods 0.000 claims 1
- 230000003053 immunization Effects 0.000 claims 1
- 238000002649 immunization Methods 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022162584A JP2022189863A (ja) | 2016-09-12 | 2022-10-07 | ゲノム編集初代ｂ細胞ならびに作製方法および使用方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662393512P | 2016-09-12 | 2016-09-12 | |
| US62/393,512 | 2016-09-12 | ||
| PCT/US2017/051182 WO2018049401A1 (en) | 2016-09-12 | 2017-09-12 | Genome edited primary b cell and methods of making and using |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022162584A Division JP2022189863A (ja) | 2016-09-12 | 2022-10-07 | ゲノム編集初代ｂ細胞ならびに作製方法および使用方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019526270A JP2019526270A (ja) | 2019-09-19 |
| JP2019526270A5 true JP2019526270A5 (enExample) | 2020-10-22 |
Family
ID=61562180
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019513999A Withdrawn JP2019526270A (ja) | 2016-09-12 | 2017-09-12 | ゲノム編集初代ｂ細胞ならびに作製方法および使用方法 |
| JP2022162584A Pending JP2022189863A (ja) | 2016-09-12 | 2022-10-07 | ゲノム編集初代ｂ細胞ならびに作製方法および使用方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022162584A Pending JP2022189863A (ja) | 2016-09-12 | 2022-10-07 | ゲノム編集初代ｂ細胞ならびに作製方法および使用方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20220168342A1 (enExample) |
| EP (1) | EP3509606A4 (enExample) |
| JP (2) | JP2019526270A (enExample) |
| CN (1) | CN109843303A (enExample) |
| AU (1) | AU2017322733B2 (enExample) |
| CA (1) | CA3036820A1 (enExample) |
| WO (1) | WO2018049401A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2018235957B2 (en) | 2017-03-16 | 2024-02-01 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Engraftable cell-based immunotherapy for long-term delivery of therapeutic proteins |
| AU2020392222A1 (en) * | 2019-11-27 | 2022-06-09 | Board Of Regents, The University Of Texas System | Large-scale combined CAR transduction and CRISPR gene editing of B cells |
| WO2023283585A2 (en) * | 2021-07-06 | 2023-01-12 | Vor Biopharma Inc. | Inhibitor oligonucleotides and methods of use thereof |
| WO2023010125A1 (en) * | 2021-07-29 | 2023-02-02 | Regents Of The University Of Minnesota | Multiplex base editing of primary human natural killer cells |
| EP4555091A2 (en) * | 2022-07-13 | 2025-05-21 | Vor Biopharma Inc. | Compositions and methods for artificial protospacer adjacent motif (pam) generation |
| WO2024196669A2 (en) * | 2023-03-17 | 2024-09-26 | Walking Fish Therapeutics, Inc. | Methods for in vivo editing of b cells |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20170354681A1 (en) * | 2014-10-24 | 2017-12-14 | Bcrt Holding Bv | T cell-based immunotherapeutics |
| EP4177336A1 (en) * | 2014-12-19 | 2023-05-10 | Immusoft Corporation | B cells for in vivo delivery of therapeutic agents |
| EP4335918A3 (en) * | 2015-04-03 | 2024-04-17 | Dana-Farber Cancer Institute, Inc. | Composition and methods of genome editing of b-cells |
-
2017
- 2017-09-12 JP JP2019513999A patent/JP2019526270A/ja not_active Withdrawn
- 2017-09-12 CN CN201780059655.8A patent/CN109843303A/zh active Pending
- 2017-09-12 WO PCT/US2017/051182 patent/WO2018049401A1/en not_active Ceased
- 2017-09-12 AU AU2017322733A patent/AU2017322733B2/en active Active
- 2017-09-12 CA CA3036820A patent/CA3036820A1/en active Pending
- 2017-09-12 EP EP17849776.4A patent/EP3509606A4/en active Pending
- 2017-09-12 US US16/332,555 patent/US20220168342A1/en active Pending
-
2022
- 2022-10-07 JP JP2022162584A patent/JP2022189863A/ja active Pending
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