JP2014240404A5 - - Google Patents
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- Publication number
- JP2014240404A5 JP2014240404A5 JP2014154372A JP2014154372A JP2014240404A5 JP 2014240404 A5 JP2014240404 A5 JP 2014240404A5 JP 2014154372 A JP2014154372 A JP 2014154372A JP 2014154372 A JP2014154372 A JP 2014154372A JP 2014240404 A5 JP2014240404 A5 JP 2014240404A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- regulatory
- cell epitope
- cell
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000001744 T-lymphocyte Anatomy 0.000 claims 12
- 210000003289 regulatory T cell Anatomy 0.000 claims 11
- 239000000203 mixture Substances 0.000 claims 9
- 239000000427 antigen Substances 0.000 claims 7
- 102000036639 antigens Human genes 0.000 claims 7
- 108091007433 antigens Proteins 0.000 claims 7
- 239000012472 biological sample Substances 0.000 claims 5
- 108090000765 processed proteins & peptides Proteins 0.000 claims 5
- 229920001184 polypeptide Polymers 0.000 claims 4
- 102000004196 processed proteins & peptides Human genes 0.000 claims 4
- 230000028993 immune response Effects 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 230000005867 T cell response Effects 0.000 claims 2
- 239000013566 allergen Substances 0.000 claims 2
- 230000002401 inhibitory effect Effects 0.000 claims 2
- 230000001404 mediated effect Effects 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 210000003719 b-lymphocyte Anatomy 0.000 claims 1
- 230000036755 cellular response Effects 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 210000003162 effector t lymphocyte Anatomy 0.000 claims 1
- 210000002443 helper t lymphocyte Anatomy 0.000 claims 1
- 210000002602 induced regulatory T cell Anatomy 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 210000002501 natural regulatory T cell Anatomy 0.000 claims 1
- 230000004936 stimulating effect Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US89834707P | 2007-01-30 | 2007-01-30 | |
| US60/898,347 | 2007-01-30 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011247226A Division JP5643739B2 (ja) | 2007-01-30 | 2011-11-11 | 調節性ｔ細胞エピトープ、組成物およびその使用 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017064298A Division JP6472476B2 (ja) | 2007-01-30 | 2017-03-29 | 調節性ｔ細胞エピトープ、組成物およびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014240404A JP2014240404A (ja) | 2014-12-25 |
| JP2014240404A5 true JP2014240404A5 (enExample) | 2015-02-12 |
| JP6121369B2 JP6121369B2 (ja) | 2017-04-26 |
Family
ID=39674696
Family Applications (10)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009548278A Expired - Fee Related JP4866467B2 (ja) | 2007-01-30 | 2008-01-29 | 調節性ｔ細胞エピトープ、組成物およびその使用 |
| JP2011247226A Expired - Fee Related JP5643739B2 (ja) | 2007-01-30 | 2011-11-11 | 調節性ｔ細胞エピトープ、組成物およびその使用 |
| JP2014154372A Active JP6121369B2 (ja) | 2007-01-30 | 2014-07-30 | 調節性ｔ細胞エピトープ、組成物およびその使用 |
| JP2017064298A Expired - Fee Related JP6472476B2 (ja) | 2007-01-30 | 2017-03-29 | 調節性ｔ細胞エピトープ、組成物およびその使用 |
| JP2019008352A Pending JP2019089793A (ja) | 2007-01-30 | 2019-01-22 | 調節性ｔ細胞エピトープ、組成物およびその使用 |
| JP2021011596A Withdrawn JP2021073255A (ja) | 2007-01-30 | 2021-01-28 | 調節性ｔ細胞エピトープ、組成物およびその使用 |
| JP2021072446A Pending JP2021107443A (ja) | 2007-01-30 | 2021-04-22 | 調節性ｔ細胞エピトープ、組成物およびその使用 |
| JP2021072455A Pending JP2021107444A (ja) | 2007-01-30 | 2021-04-22 | 調節性ｔ細胞エピトープ、組成物およびその使用 |
| JP2022155804A Pending JP2022177270A (ja) | 2007-01-30 | 2022-09-29 | 調節性ｔ細胞エピトープ、組成物およびその使用 |
| JP2024033497A Pending JP2024059975A (ja) | 2007-01-30 | 2024-03-06 | 調節性ｔ細胞エピトープ、組成物およびその使用 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009548278A Expired - Fee Related JP4866467B2 (ja) | 2007-01-30 | 2008-01-29 | 調節性ｔ細胞エピトープ、組成物およびその使用 |
| JP2011247226A Expired - Fee Related JP5643739B2 (ja) | 2007-01-30 | 2011-11-11 | 調節性ｔ細胞エピトープ、組成物およびその使用 |
Family Applications After (7)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017064298A Expired - Fee Related JP6472476B2 (ja) | 2007-01-30 | 2017-03-29 | 調節性ｔ細胞エピトープ、組成物およびその使用 |
| JP2019008352A Pending JP2019089793A (ja) | 2007-01-30 | 2019-01-22 | 調節性ｔ細胞エピトープ、組成物およびその使用 |
| JP2021011596A Withdrawn JP2021073255A (ja) | 2007-01-30 | 2021-01-28 | 調節性ｔ細胞エピトープ、組成物およびその使用 |
| JP2021072446A Pending JP2021107443A (ja) | 2007-01-30 | 2021-04-22 | 調節性ｔ細胞エピトープ、組成物およびその使用 |
| JP2021072455A Pending JP2021107444A (ja) | 2007-01-30 | 2021-04-22 | 調節性ｔ細胞エピトープ、組成物およびその使用 |
| JP2022155804A Pending JP2022177270A (ja) | 2007-01-30 | 2022-09-29 | 調節性ｔ細胞エピトープ、組成物およびその使用 |
| JP2024033497A Pending JP2024059975A (ja) | 2007-01-30 | 2024-03-06 | 調節性ｔ細胞エピトープ、組成物およびその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (18) | US7884184B2 (enExample) |
| EP (13) | EP2423219B1 (enExample) |
| JP (10) | JP4866467B2 (enExample) |
| KR (3) | KR20100014871A (enExample) |
| CN (4) | CN101687912B (enExample) |
| AT (1) | ATE525392T1 (enExample) |
| AU (1) | AU2008211227B2 (enExample) |
| CA (6) | CA2677073C (enExample) |
| IL (3) | IL200129A (enExample) |
| MX (3) | MX347197B (enExample) |
| WO (1) | WO2008094538A2 (enExample) |
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| JP6130307B2 (ja) | 2011-03-17 | 2017-05-17 | ザ ユニバーシティ オブ バーミンガム | 再指向性免疫療法 |
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| US9464124B2 (en) | 2011-09-12 | 2016-10-11 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
| ES2911677T3 (es) | 2011-10-03 | 2022-05-20 | Modernatx Inc | Nucleósidos, nucleótidos y ácidos nucleicos modificados, y sus usos |
| CN106986927A (zh) * | 2011-12-13 | 2017-07-28 | 法国国家科学研究中心 | 修饰肽及其用于治疗自体免疫疾病的用途 |
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| GB201203442D0 (en) | 2012-02-28 | 2012-04-11 | Univ Birmingham | Immunotherapeutic molecules and uses |
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| PT2922554T (pt) | 2012-11-26 | 2022-06-28 | Modernatx Inc | Arn modificado nas porções terminais |
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| WO2016054114A1 (en) | 2014-09-29 | 2016-04-07 | The Regents Of The University Of California | Compositions for expanding regulatory t cells (treg), and treating autoimmune and inflammatory diseases and conditions |
| US10213482B2 (en) | 2014-12-12 | 2019-02-26 | Immupharma France Sa | Methods of treating chronic inflammatory diseases |
| CN107427590B (zh) | 2015-02-02 | 2021-08-31 | 伯明翰大学 | 具有多个t细胞表位的靶向部分肽表位复合物 |
| AU2016258929B2 (en) | 2015-05-04 | 2020-10-08 | Epivax, Inc. | Modified H7 hemagluttinin glycoprotein of the influenza A/Shanghai/2/2013 H7 sequence |
| JP2018517405A (ja) * | 2015-05-04 | 2018-07-05 | エピバックス インコーポレーテッド | インフルエンザａ／上海／２／２０１３ ｈ７配列の改変ｈ７赤血球凝集素糖タンパク質 |
| PL3377103T5 (pl) | 2015-11-19 | 2025-07-07 | Revitope Limited | Komplementacja funkcjonalnego fragmentu przeciwciała dla dwuskładnikowego układu do przekierowanego zabijania niepożądanych komórek |
| PL238939B1 (pl) * | 2016-11-02 | 2021-10-18 | Instytut Immunologii I Terapii Doświadczalnej Polskiej Akademii Nauk Im Ludwika Hirszfelda We Wrocławiu | Peptyd immunosupresyjny i jego zastosowania |
| WO2019071116A1 (en) * | 2017-10-05 | 2019-04-11 | Epivax, Inc. | T REGULATORY LYMPHOCYTE EPITOPES |
| EP3622962A1 (en) * | 2018-09-14 | 2020-03-18 | advanceCOR GmbH | Short cyclic peptides for the treatment of graves' disease |
| EP3963335B1 (en) * | 2019-05-03 | 2024-08-21 | Epivax Therapeutics, Inc. | Neoantigens in cancer |
| EP4126901A4 (en) * | 2020-03-27 | 2024-04-10 | Epivax, Inc. | Regulatory t cell epitopes |
| CA3170819A1 (en) * | 2020-03-27 | 2021-09-30 | Biotest Ag | Protein comprising at least one regulatory t cell activating epitope |
| CN111856020B (zh) * | 2020-06-19 | 2022-09-27 | 南方医科大学南方医院 | 乙型肝炎病毒（hbv）特异性t细胞检测方法及其应用 |
| US20230321237A1 (en) * | 2020-08-13 | 2023-10-12 | Epivax, Inc. | Regulatory t cell epitopes |
| JP2023543801A (ja) * | 2020-09-25 | 2023-10-18 | エピバックス、インコーポレイテッド | レトロインベルソ制御性ｔ細胞エピトープ |
| JP2024524730A (ja) * | 2021-07-16 | 2024-07-05 | デベヴェ・テクノロジーズ | 対象におけるカシュー耐性を増大させるための免疫治療法 |
| WO2024240690A2 (en) | 2023-05-19 | 2024-11-28 | Numab Therapeutics AG | Antibody variable domains and antibodies having decreased immunogenicity |
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-
2008
- 2008-01-29 WO PCT/US2008/001148 patent/WO2008094538A2/en not_active Ceased
- 2008-01-29 KR KR1020097017996A patent/KR20100014871A/ko not_active Ceased
- 2008-01-29 CN CN200880011016.5A patent/CN101687912B/zh active Active
- 2008-01-29 MX MX2015014429A patent/MX347197B/es unknown
- 2008-01-29 CA CA2677073A patent/CA2677073C/en active Active
- 2008-01-29 CA CA2963138A patent/CA2963138C/en active Active
- 2008-01-29 CN CN202011190692.2A patent/CN112279911A/zh active Pending
- 2008-01-29 EP EP20110177609 patent/EP2423219B1/en not_active Not-in-force
- 2008-01-29 MX MX2009008230A patent/MX2009008230A/es active IP Right Grant
- 2008-01-29 KR KR1020147024226A patent/KR101722305B1/ko active Active
- 2008-01-29 US US12/021,832 patent/US7884184B2/en active Active
- 2008-01-29 EP EP12153171A patent/EP2450369A1/en not_active Withdrawn
- 2008-01-29 EP EP20110177625 patent/EP2423220B1/en not_active Not-in-force
- 2008-01-29 EP EP20110177630 patent/EP2423221B1/en not_active Not-in-force
- 2008-01-29 KR KR1020177008095A patent/KR20170037677A/ko not_active Ceased
- 2008-01-29 EP EP15153373.4A patent/EP2896630B1/en active Active
- 2008-01-29 EP EP08713321.1A patent/EP2125883B2/en not_active Not-in-force
- 2008-01-29 EP EP20120153174 patent/EP2450371B1/en not_active Not-in-force
- 2008-01-29 AU AU2008211227A patent/AU2008211227B2/en not_active Ceased
- 2008-01-29 EP EP20120153177 patent/EP2450372B1/en not_active Not-in-force
- 2008-01-29 CN CN201310685046.7A patent/CN103755789B/zh active Active
- 2008-01-29 AT AT08713321T patent/ATE525392T1/de not_active IP Right Cessation
- 2008-01-29 CN CN201610958012.4A patent/CN107011431B/zh active Active
- 2008-01-29 EP EP12153173A patent/EP2450370A1/en not_active Withdrawn
- 2008-01-29 CA CA3161849A patent/CA3161849A1/en active Pending
- 2008-01-29 CA CA2915168A patent/CA2915168C/en active Active
- 2008-01-29 CA CA3001783A patent/CA3001783C/en active Active
- 2008-01-29 EP EP12153166A patent/EP2450367A1/en not_active Withdrawn
- 2008-01-29 EP EP12153170A patent/EP2450368A1/en not_active Withdrawn
- 2008-01-29 CA CA3034396A patent/CA3034396C/en active Active
- 2008-01-29 EP EP12153164A patent/EP2450366A1/en not_active Withdrawn
- 2008-01-29 JP JP2009548278A patent/JP4866467B2/ja not_active Expired - Fee Related
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2009
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- 2009-07-30 MX MX2018015933A patent/MX2018015933A/es unknown
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2010
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2011
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2014
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2015
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2016
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2017
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2018
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2019
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2021
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