JP2019526270A - ゲノム編集初代ｂ細胞ならびに作製方法および使用方法 - Google Patents

ゲノム編集初代ｂ細胞ならびに作製方法および使用方法 Download PDF

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JP2019526270A
JP2019526270A JP2019513999A JP2019513999A JP2019526270A JP 2019526270 A JP2019526270 A JP 2019526270A JP 2019513999 A JP2019513999 A JP 2019513999A JP 2019513999 A JP2019513999 A JP 2019513999A JP 2019526270 A JP2019526270 A JP 2019526270A
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cell
cells
genome
primary
nucleic acid
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JP2019526270A5 (enExample
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エス．モリアリティ ブランデン
エス．モリアリティ ブランデン
ハンゼカー ジョン
ハンゼカー ジョン
ジョンソン マシュー
ジョンソン マシュー
ラオハラウィー カナット
ラオハラウィー カナット
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University of Minnesota Twin Cities
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
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JP2019513999A 2016-09-12 2017-09-12 ゲノム編集初代ｂ細胞ならびに作製方法および使用方法 Withdrawn JP2019526270A (ja)

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JP2022162584A JP2022189863A (ja) 2016-09-12 2022-10-07 ゲノム編集初代ｂ細胞ならびに作製方法および使用方法

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US201662393512P 2016-09-12 2016-09-12
US62/393,512 2016-09-12
PCT/US2017/051182 WO2018049401A1 (en) 2016-09-12 2017-09-12 Genome edited primary b cell and methods of making and using

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EP (1) EP3509606A4 (enExample)
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CN (1) CN109843303A (enExample)
AU (1) AU2017322733B2 (enExample)
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Families Citing this family (6)

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AU2018235957B2 (en) 2017-03-16 2024-02-01 Seattle Children's Hospital (dba Seattle Children's Research Institute) Engraftable cell-based immunotherapy for long-term delivery of therapeutic proteins
AU2020392222A1 (en) * 2019-11-27 2022-06-09 Board Of Regents, The University Of Texas System Large-scale combined CAR transduction and CRISPR gene editing of B cells
WO2023283585A2 (en) * 2021-07-06 2023-01-12 Vor Biopharma Inc. Inhibitor oligonucleotides and methods of use thereof
WO2023010125A1 (en) * 2021-07-29 2023-02-02 Regents Of The University Of Minnesota Multiplex base editing of primary human natural killer cells
EP4555091A2 (en) * 2022-07-13 2025-05-21 Vor Biopharma Inc. Compositions and methods for artificial protospacer adjacent motif (pam) generation
WO2024196669A2 (en) * 2023-03-17 2024-09-26 Walking Fish Therapeutics, Inc. Methods for in vivo editing of b cells

Citations (1)

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Publication number Priority date Publication date Assignee Title
WO2016100932A1 (en) * 2014-12-19 2016-06-23 Immusoft Corporation B cells for in vivo delivery of therapeutic agents

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US20170354681A1 (en) * 2014-10-24 2017-12-14 Bcrt Holding Bv T cell-based immunotherapeutics
EP4335918A3 (en) * 2015-04-03 2024-04-17 Dana-Farber Cancer Institute, Inc. Composition and methods of genome editing of b-cells

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016100932A1 (en) * 2014-12-19 2016-06-23 Immusoft Corporation B cells for in vivo delivery of therapeutic agents

Non-Patent Citations (2)

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Title
NATURE COMMUNICATIONS(20160309)7:10934, JPN6021043716, ISSN: 0004907033 *
PLOS ONE(2014) 9(10):E109199, JPN6021043717, ISSN: 0004907034 *

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WO2018049401A8 (en) 2019-04-04
US20220168342A1 (en) 2022-06-02
CA3036820A1 (en) 2018-03-15
EP3509606A1 (en) 2019-07-17
CN109843303A (zh) 2019-06-04
JP2022189863A (ja) 2022-12-22
AU2017322733B2 (en) 2024-05-09
EP3509606A4 (en) 2020-10-07
WO2018049401A1 (en) 2018-03-15
AU2017322733A1 (en) 2019-04-11

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