JP2013531978A5 - - Google Patents

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Publication number
JP2013531978A5
JP2013531978A5 JP2013512251A JP2013512251A JP2013531978A5 JP 2013531978 A5 JP2013531978 A5 JP 2013531978A5 JP 2013512251 A JP2013512251 A JP 2013512251A JP 2013512251 A JP2013512251 A JP 2013512251A JP 2013531978 A5 JP2013531978 A5 JP 2013531978A5
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JP
Japan
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pdhk
nucleic acid
acid sequence
cell
heterologous nucleic
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JP2013512251A
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English (en)
Japanese (ja)
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JP6050226B2 (ja
JP2013531978A (ja
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Priority claimed from PCT/US2011/038191 external-priority patent/WO2011150241A2/en
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Publication of JP2013531978A5 publication Critical patent/JP2013531978A5/ja
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JP2013512251A 2010-05-28 2011-05-26 Ｌｄｈ及びｐｄｈｋ発現を下方制御することによる乳酸レベルの低下及びポリペプチド生産の増加 Active JP6050226B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US34972710P 2010-05-28 2010-05-28
US61/349,727 2010-05-28
PCT/US2011/038191 WO2011150241A2 (en) 2010-05-28 2011-05-26 Decreasing lactate level and increasing polypeptide production by downregulating the expression of lactate dehydrogenase and pyruvate dehydrogenase kinase

Related Child Applications (1)

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JP2016227876A Division JP6325060B2 (ja) 2010-05-28 2016-11-24 Ｌｄｈ及びｐｄｈｋ発現を下方制御することによる乳酸レベルの低下及びポリペプチド生産の増加

Publications (3)

Publication Number Publication Date
JP2013531978A JP2013531978A (ja) 2013-08-15
JP2013531978A5 true JP2013531978A5 (enExample) 2014-07-10
JP6050226B2 JP6050226B2 (ja) 2016-12-21

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Family Applications (3)

Application Number Title Priority Date Filing Date
JP2013512251A Active JP6050226B2 (ja) 2010-05-28 2011-05-26 Ｌｄｈ及びｐｄｈｋ発現を下方制御することによる乳酸レベルの低下及びポリペプチド生産の増加
JP2016227876A Active JP6325060B2 (ja) 2010-05-28 2016-11-24 Ｌｄｈ及びｐｄｈｋ発現を下方制御することによる乳酸レベルの低下及びポリペプチド生産の増加
JP2018076234A Active JP6706642B2 (ja) 2010-05-28 2018-04-11 Ｌｄｈ及びｐｄｈｋ発現を下方制御することによる乳酸レベルの低下及びポリペプチド生産の増加

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JP2016227876A Active JP6325060B2 (ja) 2010-05-28 2016-11-24 Ｌｄｈ及びｐｄｈｋ発現を下方制御することによる乳酸レベルの低下及びポリペプチド生産の増加
JP2018076234A Active JP6706642B2 (ja) 2010-05-28 2018-04-11 Ｌｄｈ及びｐｄｈｋ発現を下方制御することによる乳酸レベルの低下及びポリペプチド生産の増加

Country Status (15)

Country Link
US (4) US9487809B2 (enExample)
EP (1) EP2576580B1 (enExample)
JP (3) JP6050226B2 (enExample)
KR (3) KR20190067277A (enExample)
CN (1) CN102985437B (enExample)
BR (1) BR112012030197A2 (enExample)
CA (1) CA2800728C (enExample)
DK (1) DK2576580T3 (enExample)
ES (1) ES2599412T3 (enExample)
HU (1) HUE030820T2 (enExample)
MX (3) MX343604B (enExample)
PL (1) PL2576580T3 (enExample)
RU (1) RU2614125C2 (enExample)
SI (1) SI2576580T1 (enExample)
WO (1) WO2011150241A2 (enExample)

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