JP2013526837A5 - - Google Patents
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- Publication number
- JP2013526837A5 JP2013526837A5 JP2012539021A JP2012539021A JP2013526837A5 JP 2013526837 A5 JP2013526837 A5 JP 2013526837A5 JP 2012539021 A JP2012539021 A JP 2012539021A JP 2012539021 A JP2012539021 A JP 2012539021A JP 2013526837 A5 JP2013526837 A5 JP 2013526837A5
- Authority
- JP
- Japan
- Prior art keywords
- recombinant listeria
- listeria strain
- her2
- pharmaceutical composition
- neu
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26027709P | 2009-11-11 | 2009-11-11 | |
| PCT/US2010/056534 WO2011060260A2 (en) | 2009-11-11 | 2010-11-12 | Compositions and methods for prevention of escape mutation in the treatment of her2/neu over-expressing tumors |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016152578A Division JP6329211B2 (ja) | 2016-08-03 | 2016-08-03 | 脳腫瘍または乳腺腫瘍の発症を遅延させるための医薬の製造における組換えリステリア株の使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013526837A JP2013526837A (ja) | 2013-06-27 |
| JP2013526837A5 true JP2013526837A5 (enExample) | 2013-12-26 |
| JP5985397B2 JP5985397B2 (ja) | 2016-09-06 |
Family
ID=43992418
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012539021A Expired - Fee Related JP5985397B2 (ja) | 2009-11-11 | 2010-11-12 | 組換えリステリア株およびそれを含む免疫原性組成物 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US9084747B2 (enExample) |
| EP (1) | EP2498808A4 (enExample) |
| JP (1) | JP5985397B2 (enExample) |
| WO (1) | WO2011060260A2 (enExample) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9012141B2 (en) | 2000-03-27 | 2015-04-21 | Advaxis, Inc. | Compositions and methods comprising KLK3 of FOLH1 antigen |
| WO2009143167A2 (en) | 2008-05-19 | 2009-11-26 | Advaxis | Dual delivery system for heterologous antigens |
| US9650639B2 (en) | 2008-05-19 | 2017-05-16 | Advaxis, Inc. | Dual delivery system for heterologous antigens |
| US9017660B2 (en) * | 2009-11-11 | 2015-04-28 | Advaxis, Inc. | Compositions and methods for prevention of escape mutation in the treatment of Her2/neu over-expressing tumors |
| WO2011060260A2 (en) | 2009-11-11 | 2011-05-19 | Advaxis | Compositions and methods for prevention of escape mutation in the treatment of her2/neu over-expressing tumors |
| US10016617B2 (en) | 2009-11-11 | 2018-07-10 | The Trustees Of The University Of Pennsylvania | Combination immuno therapy and radiotherapy for the treatment of Her-2-positive cancers |
| CN107412756A (zh) | 2010-10-01 | 2017-12-01 | 宾夕法尼亚大学理事会 | 李斯特菌疫苗载体用于在寄生虫感染的个体中扭转免疫无应答的用途 |
| US9040053B2 (en) * | 2010-10-19 | 2015-05-26 | Merial, Inc. | Her2 DNA vaccine as adjunct treatment for cancers in companion animals |
| WO2012125551A1 (en) | 2011-03-11 | 2012-09-20 | Advaxis | Listeria-based adjuvants |
| WO2013110030A2 (en) | 2012-01-19 | 2013-07-25 | Duke University | Vaccines against antigens involved in therapy resistance and methods of using same |
| SG10201700392UA (en) * | 2012-03-12 | 2017-03-30 | Advaxis Inc | Suppressor cell function inhibition following listeria vaccine treatment |
| EP3107566A4 (en) | 2014-02-18 | 2017-10-11 | Advaxis, Inc. | Biomarker directed multi-target immunotherapy |
| CN103897067B (zh) * | 2014-04-16 | 2016-04-13 | 中国医学科学院基础医学研究所 | 一种治疗肿瘤的重组多肽 |
| SG11201608820WA (en) | 2014-04-24 | 2016-11-29 | Advaxis Inc | Recombinant listeria vaccine strains and methods of producing the same |
| JP2017514904A (ja) * | 2014-05-02 | 2017-06-08 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | Her2陽性ガンの治療のための免疫療法および放射線療法の併用 |
| WO2016007504A1 (en) | 2014-07-07 | 2016-01-14 | Duke University | Vaccines against an oncogenic isoform of esr1 and methods of using the same |
| WO2016007499A1 (en) | 2014-07-07 | 2016-01-14 | Duke University | Vaccines against an oncogenic isoform of her2 (erbb2) and methods of using the same |
| WO2016011320A1 (en) * | 2014-07-18 | 2016-01-21 | Advaxis, Inc. | Bivalent listeria-based delivery system of heterologous antigens |
| SG11201702857PA (en) * | 2014-10-14 | 2017-05-30 | Univ Pennsylvania | Recombinant listeria vaccine strains and methods of using the same in cancer immunotherapy |
| MA41644A (fr) | 2015-03-03 | 2018-01-09 | Advaxis Inc | Compositions à base de listeria comprenant un système d'expression de minigènes codant pour des peptides, et leurs procédés d'utilisation |
| CN107847611A (zh) * | 2015-05-26 | 2018-03-27 | 阿德瓦希斯公司 | 个性化的基于递送载体的免疫疗法及其用途 |
| US20170199961A1 (en) | 2015-12-16 | 2017-07-13 | Gritstone Oncology, Inc. | Neoantigen Identification, Manufacture, and Use |
| CN108697779B (zh) | 2016-01-07 | 2023-09-19 | 杜克大学 | 癌症疫苗和递送方法 |
| US11224665B2 (en) | 2016-10-05 | 2022-01-18 | Duke University | Mitochondrial antiviral signaling (MAVS) protein compositions and methods of using the same |
| US10487143B2 (en) | 2016-10-05 | 2019-11-26 | Duke University | Vaccines against HER3 antigens and methods of using the same |
| CN110506107A (zh) | 2016-11-30 | 2019-11-26 | 阿德瓦希斯公司 | 靶向复发性癌症突变的免疫原性组合物及其使用方法 |
| US11179339B2 (en) | 2017-09-19 | 2021-11-23 | Advaxis, Inc. | Compositions and methods for lyophilization of bacteria or listeria strains |
| ES3029080T3 (en) | 2017-10-10 | 2025-06-23 | Seattle Project Corp | Neoantigen identification using hotspots |
| US11885815B2 (en) | 2017-11-22 | 2024-01-30 | Gritstone Bio, Inc. | Reducing junction epitope presentation for neoantigens |
| EP3762719A1 (en) | 2018-03-09 | 2021-01-13 | Advaxis, Inc. | Compositions and methods for evaluating attenuation and infectivity of listeria strains |
| EP3785029A1 (en) | 2018-04-27 | 2021-03-03 | Advaxis, Inc. | Compositions and methods for evaluating potency of listeria-based immunotherapeutics |
| JP2023532444A (ja) | 2020-06-23 | 2023-07-28 | ザ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・コロラド・ア・ボディ・コーポレイト | 呼吸器病原体を診断し、covid-19に関連する転帰を予測する方法 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4458066A (en) * | 1980-02-29 | 1984-07-03 | University Patents, Inc. | Process for preparing polynucleotides |
| US7662396B2 (en) * | 2001-03-26 | 2010-02-16 | The Trustees Of The University Of Pennsylvania | Compositions and methods for enhancing the immunogenicity of antigens |
| US7794729B2 (en) * | 1994-11-08 | 2010-09-14 | The Trustees Of The University Of Pennsylvania | Methods and compositions for immunotherapy of cancer |
| US7820180B2 (en) * | 2004-09-24 | 2010-10-26 | The Trustees Of The University Of Pennsylvania | Listeria-based and LLO-based vaccines |
| US8114414B2 (en) | 1994-11-08 | 2012-02-14 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treatment of cervical cancer |
| EP0831854A4 (en) | 1995-06-06 | 2001-01-24 | Isis Pharmaceuticals Inc | OLIGONUCLEOTIDS WITH PHOSPHOROTHIOATE BINDINGS OF HIGH CHIRAL PURITY |
| US5985662A (en) | 1995-07-13 | 1999-11-16 | Isis Pharmaceuticals Inc. | Antisense inhibition of hepatitis B virus replication |
| US5922583A (en) * | 1995-10-17 | 1999-07-13 | Biostar Inc. | Methods for production of recombinant plasmids |
| US6740506B2 (en) * | 1995-12-07 | 2004-05-25 | Diversa Corporation | End selection in directed evolution |
| KR100574215B1 (ko) * | 1997-04-17 | 2006-04-27 | 세키스이가가쿠 고교가부시키가이샤 | 도전성 미립자 |
| US6099848A (en) | 1997-11-18 | 2000-08-08 | The Trustees Of The University Of Pennsylvania | Immunogenic compositions comprising DAL/DAT double-mutant, auxotrophic, attenuated strains of Listeria and their methods of use |
| US7198920B1 (en) * | 1999-01-29 | 2007-04-03 | Corika Corporation | HER-2/neu fusion proteins |
| US6855320B2 (en) * | 2000-03-29 | 2005-02-15 | The Trustees Of The University Of Pennsylvania | Fusion of non-hemolytic, truncated form of listeriolysin O to antigens to enhance immunogenicity |
| CA2486980A1 (en) | 2002-05-29 | 2003-12-11 | The Regents Of The University Of California | Attenuated listeria spp. and methods for using the same |
| EP1408048A1 (en) | 2002-10-07 | 2004-04-14 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Vaccines of enhanced immunogenicity, and methods for preparing such vaccines |
| CA2512812A1 (en) * | 2003-01-09 | 2004-07-29 | The Trustees Of The University Of Pennsylvania | Compositions, methods and kits for enhancing the immunogenicity of a bacterial vaccine vector |
| DE10310261A1 (de) * | 2003-03-05 | 2004-09-23 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Identifizierung von Antigen-Epitopen |
| EP1682173A4 (en) * | 2003-10-15 | 2007-10-31 | Medimmune Inc | EPHA2 VACCINE ON LISTERIA BASE |
| US7855064B2 (en) * | 2004-08-13 | 2010-12-21 | The Trustees Of The University Of Pennsylvania | Antibiotic resistance free vaccines and methods for constructing and using same |
| PT2942391T (pt) | 2004-08-13 | 2018-10-09 | Univ Pennsylvania | Métodos de produção de vacinas não resistentes aos antibióticos |
| WO2007061848A2 (en) | 2005-11-17 | 2007-05-31 | The Trustees Of The University Of Pennsylvania | Methods for producing, growing, and preserving listeria vaccine vectors |
| US20070207171A1 (en) * | 2006-03-01 | 2007-09-06 | Cerus Corporation | Engineered listeria and methods of use thereof |
| US8268326B2 (en) * | 2006-08-15 | 2012-09-18 | The Trustees Of The University Of Pennsylvania | Compositions comprising HMW-MAA and fragments thereof, and methods of use thereof |
| EP2147092A4 (en) | 2007-04-16 | 2010-06-09 | Univ Pennsylvania | ANTIBIOTIC RESISTANCE-FREE LISTERIA TRIBES AND METHOD OF CONSTRUCTING AND USING THEREOF |
| US9017660B2 (en) * | 2009-11-11 | 2015-04-28 | Advaxis, Inc. | Compositions and methods for prevention of escape mutation in the treatment of Her2/neu over-expressing tumors |
| WO2009143167A2 (en) | 2008-05-19 | 2009-11-26 | Advaxis | Dual delivery system for heterologous antigens |
| WO2011060260A2 (en) | 2009-11-11 | 2011-05-19 | Advaxis | Compositions and methods for prevention of escape mutation in the treatment of her2/neu over-expressing tumors |
| US20110223187A1 (en) * | 2010-02-15 | 2011-09-15 | Vafa Shahabi | Live listeria-based vaccines for central nervous system therapy |
-
2010
- 2010-11-12 WO PCT/US2010/056534 patent/WO2011060260A2/en not_active Ceased
- 2010-11-12 JP JP2012539021A patent/JP5985397B2/ja not_active Expired - Fee Related
- 2010-11-12 EP EP10830785.1A patent/EP2498808A4/en not_active Ceased
- 2010-11-12 US US12/945,386 patent/US9084747B2/en active Active
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