JP5985397B2 - 組換えリステリア株およびそれを含む免疫原性組成物 - Google Patents

組換えリステリア株およびそれを含む免疫原性組成物 Download PDF

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JP5985397B2
JP5985397B2 JP2012539021A JP2012539021A JP5985397B2 JP 5985397 B2 JP5985397 B2 JP 5985397B2 JP 2012539021 A JP2012539021 A JP 2012539021A JP 2012539021 A JP2012539021 A JP 2012539021A JP 5985397 B2 JP5985397 B2 JP 5985397B2
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another embodiment
recombinant listeria
listeria strain
neu
her2
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JP2013526837A (ja
JP2013526837A5 (enExample
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シャハビ、バッファ
ワレチャ、アヌ
シー. マシアグ、パウロ
シー. マシアグ、パウロ
パターソン、イボンヌ
エム. シーベイ、マシュー
エム. シーベイ、マシュー
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アドバクシス インコーポレイテッド
アドバクシス インコーポレイテッド
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001102Receptors, cell surface antigens or cell surface determinants
    • A61K39/001103Receptors for growth factors
    • A61K39/001106Her-2/neu/ErbB2, Her-3/ErbB3 or Her 4/ErbB4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2012539021A 2009-11-11 2010-11-12 組換えリステリア株およびそれを含む免疫原性組成物 Expired - Fee Related JP5985397B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26027709P 2009-11-11 2009-11-11
PCT/US2010/056534 WO2011060260A2 (en) 2009-11-11 2010-11-12 Compositions and methods for prevention of escape mutation in the treatment of her2/neu over-expressing tumors

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016152578A Division JP6329211B2 (ja) 2016-08-03 2016-08-03 脳腫瘍または乳腺腫瘍の発症を遅延させるための医薬の製造における組換えリステリア株の使用

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JP2013526837A JP2013526837A (ja) 2013-06-27
JP2013526837A5 JP2013526837A5 (enExample) 2013-12-26
JP5985397B2 true JP5985397B2 (ja) 2016-09-06

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JP2012539021A Expired - Fee Related JP5985397B2 (ja) 2009-11-11 2010-11-12 組換えリステリア株およびそれを含む免疫原性組成物

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US (1) US9084747B2 (enExample)
EP (1) EP2498808A4 (enExample)
JP (1) JP5985397B2 (enExample)
WO (1) WO2011060260A2 (enExample)

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Publication number Publication date
WO2011060260A2 (en) 2011-05-19
WO2011060260A3 (en) 2011-08-18
US9084747B2 (en) 2015-07-21
JP2013526837A (ja) 2013-06-27
EP2498808A2 (en) 2012-09-19
EP2498808A4 (en) 2014-01-08
US20110142791A1 (en) 2011-06-16

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