JP2013519680A5 - - Google Patents

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Publication number
JP2013519680A5
JP2013519680A5 JP2012552997A JP2012552997A JP2013519680A5 JP 2013519680 A5 JP2013519680 A5 JP 2013519680A5 JP 2012552997 A JP2012552997 A JP 2012552997A JP 2012552997 A JP2012552997 A JP 2012552997A JP 2013519680 A5 JP2013519680 A5 JP 2013519680A5
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JP
Japan
Prior art keywords
hydroxy
chromen
trifluoromethyl
group
oxo
Prior art date
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Application number
JP2012552997A
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English (en)
Japanese (ja)
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JP5878484B2 (ja
JP2013519680A (ja
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Priority claimed from PCT/US2011/024353 external-priority patent/WO2011100433A1/en
Publication of JP2013519680A publication Critical patent/JP2013519680A/ja
Publication of JP2013519680A5 publication Critical patent/JP2013519680A5/ja
Application granted granted Critical
Publication of JP5878484B2 publication Critical patent/JP5878484B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2012552997A 2010-02-12 2011-02-10 新規のs−ニトロソグルタチオンレダクターゼ阻害剤 Expired - Fee Related JP5878484B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30395210P 2010-02-12 2010-02-12
US61/303,952 2010-02-12
PCT/US2011/024353 WO2011100433A1 (en) 2010-02-12 2011-02-10 Novel s-nitrosoglutathione reductase inhibitors

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015190968A Division JP2016040285A (ja) 2010-02-12 2015-09-29 新規のs−ニトロソグルタチオンレダクターゼ阻害剤

Publications (3)

Publication Number Publication Date
JP2013519680A JP2013519680A (ja) 2013-05-30
JP2013519680A5 true JP2013519680A5 (enExample) 2014-03-20
JP5878484B2 JP5878484B2 (ja) 2016-03-08

Family

ID=44368117

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2012552997A Expired - Fee Related JP5878484B2 (ja) 2010-02-12 2011-02-10 新規のs−ニトロソグルタチオンレダクターゼ阻害剤
JP2015190968A Pending JP2016040285A (ja) 2010-02-12 2015-09-29 新規のs−ニトロソグルタチオンレダクターゼ阻害剤

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2015190968A Pending JP2016040285A (ja) 2010-02-12 2015-09-29 新規のs−ニトロソグルタチオンレダクターゼ阻害剤

Country Status (20)

Country Link
US (3) US8759548B2 (enExample)
EP (1) EP2533638B1 (enExample)
JP (2) JP5878484B2 (enExample)
KR (1) KR20120138746A (enExample)
CN (1) CN102869255B (enExample)
AU (1) AU2011215833B2 (enExample)
BR (1) BR112012019529A2 (enExample)
CA (1) CA2787633A1 (enExample)
DK (1) DK2533638T3 (enExample)
ES (1) ES2565345T3 (enExample)
HR (1) HRP20160450T1 (enExample)
HU (1) HUE029012T2 (enExample)
IL (1) IL220956A (enExample)
PL (1) PL2533638T3 (enExample)
RS (1) RS54618B1 (enExample)
RU (1) RU2585763C2 (enExample)
SI (1) SI2533638T1 (enExample)
SM (1) SMT201600135B (enExample)
WO (1) WO2011100433A1 (enExample)
ZA (1) ZA201205374B (enExample)

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WO2011099978A1 (en) 2010-02-12 2011-08-18 N30 Pharmaceuticals, Llc Chromone inhibitors of s-nitrosoglutathione reductase
SI2533638T1 (sl) 2010-02-12 2016-05-31 Nivalis Therapeutics, Inc. Novi inhibitorji S-nitrozoglutation reduktaze
SI2624695T1 (sl) 2010-10-08 2016-01-29 Nivalis Therapeutics, Inc. Nove substituirane kinolinske spojine kot inhibitorji S-nitrozoglutation reduktaze
WO2012083165A1 (en) 2010-12-16 2012-06-21 N30 Pharmaceuticals, Llc Novel substituted bicyclic aromatic compounds as s-nitrosoglutathione reductase inhibitors
WO2012170371A1 (en) * 2011-06-10 2012-12-13 N30 Pharmaceuticals, Llc Compounds as s-nitrosoglutathione reductase inhibitors
MX2014005297A (es) 2011-10-31 2014-09-11 Xenon Pharmaceuticals Inc Compuestos de bencenosulfonamida y su uso como agentes terapeuticos.
CA2855019A1 (en) 2011-10-31 2013-05-10 Xenon Pharmaceuticals Inc. Biaryl ether sulfonamides and their use as therapeutic agents
CN104718188B (zh) * 2012-05-22 2018-08-21 基因泰克公司 N-取代的苯甲酰胺类及其在治疗疼痛中的用途
MX2015000164A (es) 2012-07-06 2015-08-12 Genentech Inc Benzamidas n-sustituidas y metodos para usarlas.
EP2968280A4 (en) 2013-03-14 2016-08-10 Genentech Inc SUBSTITUTED TRIAZOLOPYRIDINES AND METHOD OF USE THEREOF
WO2014144545A2 (en) 2013-03-15 2014-09-18 Genentech, Inc. Substituted benzoxazoles and methods of use thereof
CN105793238B (zh) 2013-11-27 2019-12-24 基因泰克公司 经取代的苯甲酰胺及其使用方法
US10005724B2 (en) 2014-07-07 2018-06-26 Genentech, Inc. Therapeutic compounds and methods of use thereof
JP2018520107A (ja) 2015-05-22 2018-07-26 ジェネンテック, インコーポレイテッド 置換ベンズアミド及びその使用方法
EP3341353A1 (en) 2015-08-27 2018-07-04 Genentech, Inc. Therapeutic compounds and methods of use thereof
WO2017044766A1 (en) 2015-09-10 2017-03-16 Nivalis Therapeutics, Inc. Solid forms of an s-nitrosoglutathione reductase inhibitor
CR20180242A (es) 2015-09-28 2018-08-10 Genentech Inc Compuestos terapéuticos y sus métodos de uso
WO2017091592A1 (en) 2015-11-25 2017-06-01 Genentech, Inc. Substituted benzamides useful as sodium channel blockers
WO2017172802A1 (en) 2016-03-30 2017-10-05 Genentech, Inc. Substituted benzamides and methods of use thereof
RU2019114964A (ru) 2016-10-17 2020-11-17 Дженентек, Инк. Терапевтические средства и способы их применения
US10793550B2 (en) 2017-03-24 2020-10-06 Genentech, Inc. 4-piperidin-n-(pyrimidin-4-yl)chroman-7-sulfonamide derivatives as sodium channel inhibitors
WO2018177993A1 (de) 2017-03-31 2018-10-04 Bayer Cropscience Aktiengesellschaft Pyrazole zur bekämpfung von arthropoden
WO2019165290A1 (en) 2018-02-26 2019-08-29 Genentech, Inc. Pyridine-sulfonamide compounds and their use against pain and related conditions
EP3774801A1 (en) 2018-03-30 2021-02-17 F. Hoffmann-La Roche AG Fused ring hydro-pyrido compounds as sodium channel inhibitors
TW202003490A (zh) 2018-05-22 2020-01-16 瑞士商赫孚孟拉羅股份公司 治療性化合物及其使用方法
JP7457795B2 (ja) * 2019-08-23 2024-03-28 ノータ ラボラトリーズ,リミティド ライアビリティ カンパニー 一酸化窒素発生システム
CN117088862B (zh) * 2023-08-22 2025-09-12 南华大学 一种硫代色元酮衍生物和应用

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WO2012170371A1 (en) * 2011-06-10 2012-12-13 N30 Pharmaceuticals, Llc Compounds as s-nitrosoglutathione reductase inhibitors

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