CN102869255B - S-亚硝基谷胱甘肽还原酶的新抑制剂 - Google Patents

S-亚硝基谷胱甘肽还原酶的新抑制剂 Download PDF

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CN102869255B
CN102869255B CN201180008906.2A CN201180008906A CN102869255B CN 102869255 B CN102869255 B CN 102869255B CN 201180008906 A CN201180008906 A CN 201180008906A CN 102869255 B CN102869255 B CN 102869255B
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hydroxy
benzopyran
compound
trifluoromethyl
oxo
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CN102869255A (zh
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孙喜成
邱键
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Nevalis Therapeutics
Nivalis Therapeutics Inc
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Nevalis Therapeutics
N30 Pharmaceuticals Inc
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/433—Thidiazoles
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyrane Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN201180008906.2A 2010-02-12 2011-02-10 S-亚硝基谷胱甘肽还原酶的新抑制剂 Expired - Fee Related CN102869255B (zh)

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US30395210P 2010-02-12 2010-02-12
US61/303,952 2010-02-12
PCT/US2011/024353 WO2011100433A1 (en) 2010-02-12 2011-02-10 Novel s-nitrosoglutathione reductase inhibitors

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CN102869255B true CN102869255B (zh) 2016-08-31

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US (3) US8759548B2 (enExample)
EP (1) EP2533638B1 (enExample)
JP (2) JP5878484B2 (enExample)
KR (1) KR20120138746A (enExample)
CN (1) CN102869255B (enExample)
AU (1) AU2011215833B2 (enExample)
BR (1) BR112012019529A2 (enExample)
CA (1) CA2787633A1 (enExample)
DK (1) DK2533638T3 (enExample)
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JP6383418B2 (ja) 2013-11-27 2018-08-29 ジェネンテック， インコーポレイテッド 置換ベンズアミド及びその使用方法
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BR112019007763A2 (pt) 2016-10-17 2019-07-02 Genentech Inc composto de fórmula, composição farmacêutica, métodos para tratar uma doença ou condição, para tratar dores, para diminuir o fluxo de íons e para tratar prurido, uso de um composto e invenção
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US9187447B2 (en) 2015-11-17
US20120289555A1 (en) 2012-11-15
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JP2013519680A (ja) 2013-05-30
JP5878484B2 (ja) 2016-03-08
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