JP2013512212A5 - - Google Patents

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JP2013512212A5
JP2013512212A5 JP2012540386A JP2012540386A JP2013512212A5 JP 2013512212 A5 JP2013512212 A5 JP 2013512212A5 JP 2012540386 A JP2012540386 A JP 2012540386A JP 2012540386 A JP2012540386 A JP 2012540386A JP 2013512212 A5 JP2013512212 A5 JP 2013512212A5
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compound
product
methyl
carbonate
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JP5859451B2 (ja
JP2013512212A (ja
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JP2012540386A 2009-11-27 2010-11-22 メチル{4,6−ジアミノ−2−[1−(2−フルオロベンジル)−1H−ピラゾロ[3,4−b]ピリジン−3−イル]ピリミジン−5−イル}メチルカルバメートの調製方法および医薬上活性な化合物として用いるためのその精製方法 Active JP5859451B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09177371 2009-11-27
EP09177371.3 2009-11-27
PCT/EP2010/067949 WO2011064171A2 (de) 2009-11-27 2010-11-22 Verfahren zur herstellung von methyl-{4,6-diamino-2-[1-(2-fluorobenzyl)-1h-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl}methylcarbamat und dessen aufreinigung für die verwendung als pharmazeutischer wirkstoff

Related Child Applications (1)

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JP2015105630A Division JP6133931B2 (ja) 2009-11-27 2015-05-25 メチル{4,6−ジアミノ−2−[1−(2−フルオロベンジル)−1H−ピラゾロ[3,4−b]ピリジン−3−イル]ピリミジン−5−イル}メチルカルバメートの調製方法および医薬上活性な化合物として用いるためのその精製方法

Publications (3)

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JP2013512212A JP2013512212A (ja) 2013-04-11
JP2013512212A5 true JP2013512212A5 (https=) 2014-01-16
JP5859451B2 JP5859451B2 (ja) 2016-02-10

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JP2012540386A Active JP5859451B2 (ja) 2009-11-27 2010-11-22 メチル{4,6−ジアミノ−2−[1−(2−フルオロベンジル)−1H−ピラゾロ[3,4−b]ピリジン−3−イル]ピリミジン−5−イル}メチルカルバメートの調製方法および医薬上活性な化合物として用いるためのその精製方法
JP2015105630A Active JP6133931B2 (ja) 2009-11-27 2015-05-25 メチル{4,6−ジアミノ−2−[1−(2−フルオロベンジル)−1H−ピラゾロ[3,4−b]ピリジン−3−イル]ピリミジン−5−イル}メチルカルバメートの調製方法および医薬上活性な化合物として用いるためのその精製方法
JP2017000073A Active JP6371871B2 (ja) 2009-11-27 2017-01-04 メチル{4,6−ジアミノ−2−[1−(2−フルオロベンジル)−1H−ピラゾロ[3,4−b]ピリジン−3−イル]ピリミジン−5−イル}メチルカルバメートの調製方法および医薬上活性な化合物として用いるためのその精製方法
JP2018128949A Active JP6514398B2 (ja) 2009-11-27 2018-07-06 メチル{4,6−ジアミノ−2−[1−(2−フルオロベンジル)−1H−ピラゾロ[3,4−b]ピリジン−3−イル]ピリミジン−5−イル}メチルカルバメートの調製方法および医薬上活性な化合物として用いるためのその精製方法

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JP2015105630A Active JP6133931B2 (ja) 2009-11-27 2015-05-25 メチル{4,6−ジアミノ−2−[1−(2−フルオロベンジル)−1H−ピラゾロ[3,4−b]ピリジン−3−イル]ピリミジン−5−イル}メチルカルバメートの調製方法および医薬上活性な化合物として用いるためのその精製方法
JP2017000073A Active JP6371871B2 (ja) 2009-11-27 2017-01-04 メチル{4,6−ジアミノ−2−[1−(2−フルオロベンジル)−1H−ピラゾロ[3,4−b]ピリジン−3−イル]ピリミジン−5−イル}メチルカルバメートの調製方法および医薬上活性な化合物として用いるためのその精製方法
JP2018128949A Active JP6514398B2 (ja) 2009-11-27 2018-07-06 メチル{4,6−ジアミノ−2−[1−(2−フルオロベンジル)−1H−ピラゾロ[3,4−b]ピリジン−3−イル]ピリミジン−5−イル}メチルカルバメートの調製方法および医薬上活性な化合物として用いるためのその精製方法

Country Status (43)

Country Link
US (5) US8492544B2 (https=)
EP (5) EP2733142B1 (https=)
JP (4) JP5859451B2 (https=)
KR (2) KR101766931B1 (https=)
CN (2) CN104059064B (https=)
AR (1) AR079134A1 (https=)
AU (3) AU2010323227B2 (https=)
BR (3) BR112012012617B8 (https=)
CA (2) CA2936852C (https=)
CL (1) CL2012001329A1 (https=)
CO (1) CO6551708A2 (https=)
CR (1) CR20120280A (https=)
CU (1) CU24084B1 (https=)
CY (1) CY1115861T1 (https=)
DK (4) DK2604608T3 (https=)
DO (2) DOP2012000144A (https=)
EA (3) EA031632B1 (https=)
EC (2) ECSP12011921A (https=)
ES (4) ES2693746T3 (https=)
GT (1) GT201200158A (https=)
HR (4) HRP20141073T1 (https=)
HU (2) HUE040328T2 (https=)
IL (4) IL219683A (https=)
JO (3) JO3107B1 (https=)
LT (2) LT2733142T (https=)
MA (1) MA33783B1 (https=)
MX (1) MX2012005938A (https=)
MY (2) MY180184A (https=)
NZ (3) NZ625983A (https=)
PE (2) PE20121742A1 (https=)
PH (1) PH12012501023A1 (https=)
PL (4) PL2504334T3 (https=)
PT (4) PT2504334E (https=)
RS (4) RS59908B1 (https=)
SI (4) SI2504334T1 (https=)
SM (1) SMT201400164B (https=)
TN (1) TN2012000257A1 (https=)
TR (1) TR201816146T4 (https=)
TW (1) TWI496781B (https=)
UA (1) UA110779C2 (https=)
UY (1) UY33048A (https=)
WO (1) WO2011064171A2 (https=)
ZA (1) ZA201204610B (https=)

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KR20210031931A (ko) 2018-07-11 2021-03-23 사이클리온 테라퓨틱스, 인크. 미토콘드리아 장애의 치료를 위한 sGC 자극제의 용도
TWI830835B (zh) 2018-12-17 2024-02-01 德商亞德維瑞醫藥有限公司 具改善性質之{4,6-二胺基-2-[5-氟-1-(2-氟芐基)-1H-吡唑並[3,4-b]吡啶-3-基]嘧啶-5-基}胺基甲酸甲酯活性化合物產物、其製造及調配物
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