JP2013056183A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2013056183A5 JP2013056183A5 JP2012248398A JP2012248398A JP2013056183A5 JP 2013056183 A5 JP2013056183 A5 JP 2013056183A5 JP 2012248398 A JP2012248398 A JP 2012248398A JP 2012248398 A JP2012248398 A JP 2012248398A JP 2013056183 A5 JP2013056183 A5 JP 2013056183A5
- Authority
- JP
- Japan
- Prior art keywords
- organ
- decellularized
- tissue
- extracellular matrix
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 210000000056 organ Anatomy 0.000 claims 43
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 claims 24
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 claims 24
- 210000002744 extracellular matrix Anatomy 0.000 claims 24
- 210000001519 tissue Anatomy 0.000 claims 24
- 210000004027 cell Anatomy 0.000 claims 20
- 241000282414 Homo sapiens Species 0.000 claims 19
- 241000283690 Bos taurus Species 0.000 claims 17
- 241001494479 Pecora Species 0.000 claims 17
- 238000000034 method Methods 0.000 claims 13
- 230000002792 vascular Effects 0.000 claims 13
- 241000282465 Canis Species 0.000 claims 9
- 210000000130 stem cell Anatomy 0.000 claims 9
- 210000002216 heart Anatomy 0.000 claims 8
- 230000001172 regenerating effect Effects 0.000 claims 8
- 241000009328 Perro Species 0.000 claims 7
- 241000282898 Sus scrofa Species 0.000 claims 5
- 210000004204 blood vessel Anatomy 0.000 claims 5
- 230000010412 perfusion Effects 0.000 claims 4
- 230000000747 cardiac effect Effects 0.000 claims 3
- 210000003734 kidney Anatomy 0.000 claims 3
- 239000007788 liquid Substances 0.000 claims 3
- 210000004072 lung Anatomy 0.000 claims 3
- 210000002027 skeletal muscle Anatomy 0.000 claims 3
- 241000282887 Suidae Species 0.000 claims 2
- 230000000735 allogeneic effect Effects 0.000 claims 2
- 210000000988 bone and bone Anatomy 0.000 claims 2
- 210000004556 brain Anatomy 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 239000012530 fluid Substances 0.000 claims 2
- 210000002429 large intestine Anatomy 0.000 claims 2
- 210000004185 liver Anatomy 0.000 claims 2
- 239000011159 matrix material Substances 0.000 claims 2
- 210000002901 mesenchymal stem cell Anatomy 0.000 claims 2
- 210000000496 pancreas Anatomy 0.000 claims 2
- 210000000813 small intestine Anatomy 0.000 claims 2
- 210000000952 spleen Anatomy 0.000 claims 2
- 210000002784 stomach Anatomy 0.000 claims 2
- 210000003932 urinary bladder Anatomy 0.000 claims 2
- 102000016911 Deoxyribonucleases Human genes 0.000 claims 1
- 108010053770 Deoxyribonucleases Proteins 0.000 claims 1
- 210000002403 aortic endothelial cell Anatomy 0.000 claims 1
- 210000001765 aortic valve Anatomy 0.000 claims 1
- 210000002798 bone marrow cell Anatomy 0.000 claims 1
- 210000001054 cardiac fibroblast Anatomy 0.000 claims 1
- 230000015271 coagulation Effects 0.000 claims 1
- 238000005345 coagulation Methods 0.000 claims 1
- 210000004351 coronary vessel Anatomy 0.000 claims 1
- 230000004069 differentiation Effects 0.000 claims 1
- 210000002308 embryonic cell Anatomy 0.000 claims 1
- 210000001671 embryonic stem cell Anatomy 0.000 claims 1
- 230000001434 glomerular Effects 0.000 claims 1
- 239000003102 growth factor Substances 0.000 claims 1
- 239000002955 immunomodulating agent Substances 0.000 claims 1
- 230000002584 immunomodulator Effects 0.000 claims 1
- 229940121354 immunomodulator Drugs 0.000 claims 1
- 210000005246 left atrium Anatomy 0.000 claims 1
- 210000005240 left ventricle Anatomy 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 210000004925 microvascular endothelial cell Anatomy 0.000 claims 1
- 210000004115 mitral valve Anatomy 0.000 claims 1
- 210000004976 peripheral blood cell Anatomy 0.000 claims 1
- 230000035755 proliferation Effects 0.000 claims 1
- 210000001147 pulmonary artery Anatomy 0.000 claims 1
- 210000003102 pulmonary valve Anatomy 0.000 claims 1
- 210000005245 right atrium Anatomy 0.000 claims 1
- 210000005241 right ventricle Anatomy 0.000 claims 1
- 230000004936 stimulating effect Effects 0.000 claims 1
- 210000000591 tricuspid valve Anatomy 0.000 claims 1
- 210000003954 umbilical cord Anatomy 0.000 claims 1
- 210000003462 vein Anatomy 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71150105P | 2005-08-26 | 2005-08-26 | |
| US60/711,501 | 2005-08-26 | ||
| US81524206P | 2006-06-19 | 2006-06-19 | |
| US60/815,242 | 2006-06-19 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008528231A Division JP2009505752A (ja) | 2005-08-26 | 2006-08-28 | 臓器および組織の脱細胞化および再細胞化 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015094591A Division JP6089062B2 (ja) | 2005-08-26 | 2015-05-07 | 臓器および組織の脱細胞化および再細胞化 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013056183A JP2013056183A (ja) | 2013-03-28 |
| JP2013056183A5 true JP2013056183A5 (enExample) | 2013-08-08 |
Family
ID=37771950
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008528231A Pending JP2009505752A (ja) | 2005-08-26 | 2006-08-28 | 臓器および組織の脱細胞化および再細胞化 |
| JP2012248398A Withdrawn JP2013056183A (ja) | 2005-08-26 | 2012-11-12 | 臓器および組織の脱細胞化および再細胞化 |
| JP2015094591A Active JP6089062B2 (ja) | 2005-08-26 | 2015-05-07 | 臓器および組織の脱細胞化および再細胞化 |
| JP2016201559A Withdrawn JP2017038948A (ja) | 2005-08-26 | 2016-10-13 | 臓器および組織の脱細胞化および再細胞化 |
| JP2019031120A Withdrawn JP2019088910A (ja) | 2005-08-26 | 2019-02-25 | 臓器および組織の脱細胞化および再細胞化 |
| JP2021082285A Active JP7286708B2 (ja) | 2005-08-26 | 2021-05-14 | 臓器および組織の脱細胞化および再細胞化 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008528231A Pending JP2009505752A (ja) | 2005-08-26 | 2006-08-28 | 臓器および組織の脱細胞化および再細胞化 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015094591A Active JP6089062B2 (ja) | 2005-08-26 | 2015-05-07 | 臓器および組織の脱細胞化および再細胞化 |
| JP2016201559A Withdrawn JP2017038948A (ja) | 2005-08-26 | 2016-10-13 | 臓器および組織の脱細胞化および再細胞化 |
| JP2019031120A Withdrawn JP2019088910A (ja) | 2005-08-26 | 2019-02-25 | 臓器および組織の脱細胞化および再細胞化 |
| JP2021082285A Active JP7286708B2 (ja) | 2005-08-26 | 2021-05-14 | 臓器および組織の脱細胞化および再細胞化 |
Country Status (15)
| Country | Link |
|---|---|
| US (5) | US8470520B2 (enExample) |
| EP (3) | EP1928519B1 (enExample) |
| JP (6) | JP2009505752A (enExample) |
| KR (3) | KR20140040293A (enExample) |
| CN (2) | CN102861359B (enExample) |
| AT (1) | ATE552007T1 (enExample) |
| AU (1) | AU2006282783B2 (enExample) |
| CA (1) | CA2618731C (enExample) |
| ES (2) | ES2384721T3 (enExample) |
| IL (2) | IL189418A (enExample) |
| MX (3) | MX369594B (enExample) |
| PL (2) | PL2431063T3 (enExample) |
| RU (2) | RU2463081C2 (enExample) |
| SG (1) | SG170731A1 (enExample) |
| WO (1) | WO2007025233A1 (enExample) |
Families Citing this family (136)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2384721T3 (es) | 2005-08-26 | 2012-07-11 | Regents Of The University Of Minnesota | Descelularización y recelularización de órganos y tejidos |
| US20100093066A1 (en) * | 2005-08-26 | 2010-04-15 | Regents Of The University Of Minnesota | Decellularization and recellularization apparatuses and systems containing the same |
| SG10201903161XA (en) | 2007-05-29 | 2019-05-30 | Christopher Reid | Methods for production and uses of multipotent cell populations |
| WO2009089110A2 (en) * | 2008-01-04 | 2009-07-16 | Boston Scientific Scimed, Inc. | Methods for repair and regeneration of bone marrow |
| AU2009266761A1 (en) * | 2008-07-02 | 2010-01-07 | Jichi Medical University | Artificial kidney precursor and process for production thereof |
| AU2009283516B2 (en) * | 2008-08-20 | 2014-02-13 | Organ Technologies Inc. | Method for restoring missing tooth and method for producing restorative material |
| US9192695B2 (en) | 2008-11-20 | 2015-11-24 | Allosource | Allografts combined with tissue derived stem cells for bone healing |
| US20120064050A1 (en) | 2009-02-04 | 2012-03-15 | Yale University | Tissue Engineering of Lung |
| WO2010099310A1 (en) * | 2009-02-26 | 2010-09-02 | Wake Forest University Health Sciences | Endothelial scaffolds |
| KR101029887B1 (ko) * | 2009-03-04 | 2011-04-18 | 서울대학교산학협력단 | 탈세포화를 위한 돼지 각막의 가공방법 |
| SG174969A1 (en) * | 2009-03-31 | 2011-11-28 | Univ Minnesota | Decellularization and recellularization of organs and tissues |
| WO2010141803A2 (en) * | 2009-06-04 | 2010-12-09 | The General Hospital Corporation | Bioartificial lung |
| US20130323708A1 (en) | 2009-07-01 | 2013-12-05 | Massachusetts Institute Of Technology | Isolated adult cells, artificial organs, rehabilitated organs, research tools, organ encasements, organ perfusion systems, and methods for preparing and utilizing the same |
| WO2011005306A2 (en) * | 2009-07-07 | 2011-01-13 | The Board Of Regents Of The University Of Texas System | Production of and uses for decellularized lung tissue |
| RU2407459C1 (ru) * | 2009-07-27 | 2010-12-27 | Учреждение Российской академии медицинских наук Научно-исследовательский институт кардиологии Сибирского отделения РАМН | Способ получения соединительно-тканного каркаса магистрального сосуда млекопитающих животных и человека |
| WO2011019822A2 (en) * | 2009-08-11 | 2011-02-17 | The Johns Hopkins University | Compositions and methods for implantation of processed adipose tissue and processed adipose tissue products |
| WO2011038023A1 (en) * | 2009-09-22 | 2011-03-31 | Colorado State University Research Foundation | Methods for processing biological tissues |
| JP2013510590A (ja) * | 2009-11-17 | 2013-03-28 | ハーバード バイオサイエンス インコーポレーテッド | 臓器を形成および/または分析するためのバイオリアクタ、システムおよび方法 |
| WO2011068778A1 (en) * | 2009-12-03 | 2011-06-09 | Lifecell Corporation | Nerve treatment devices and methods |
| BR112012014603A2 (pt) | 2009-12-17 | 2019-09-24 | Univ Kingston | método para descelularização de tecido adiposo, tecido adipose descelularizado, tecido adiposo descelularizado incluindo laminina, biosuporte, revestimento, esfera micro-transportadora e partícula |
| JP2013517292A (ja) * | 2010-01-14 | 2013-05-16 | オーガノジェネシス・インコーポレイテッド | 生物工学によって作られた組織コンストラクトならびにそれを生成および使用するための方法 |
| US10575515B2 (en) | 2010-05-04 | 2020-03-03 | The General Hospital Corporation | Methods and compositions for preserving tissues and organs |
| US9352003B1 (en) | 2010-05-14 | 2016-05-31 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
| US10130736B1 (en) | 2010-05-14 | 2018-11-20 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
| US8883210B1 (en) | 2010-05-14 | 2014-11-11 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
| CN101850136B (zh) * | 2010-06-11 | 2013-01-23 | 四川大学华西医院 | 一种植入式生物人工肝脏 |
| EP2588592B1 (en) * | 2010-06-30 | 2017-09-06 | Miromatrix Medical Inc. | Use of perfusion decellularized organs for matched recellularization |
| SG188369A1 (en) * | 2010-09-01 | 2013-04-30 | Univ Minnesota | Methods of recellularizing a tissue or organ for improved transplantability |
| KR101108983B1 (ko) * | 2010-09-17 | 2012-01-31 | 강원대학교산학협력단 | 다장기 바이오스캐폴드의 제조방법 |
| KR101273489B1 (ko) * | 2011-04-08 | 2013-06-21 | 강원대학교산학협력단 | 심폐 동시 이식용 바이오스캐폴드의 제조방법 |
| US9238793B2 (en) | 2011-04-28 | 2016-01-19 | Lifecell Corporation | Method for enzymatic treatment of tissue products |
| US10207025B2 (en) | 2011-04-28 | 2019-02-19 | Lifecell Corporation | Method for enzymatic treatment of tissue products |
| RU2639477C2 (ru) | 2011-04-28 | 2017-12-21 | Лайфселл Корпорейшн | Способ ферментативной обработки тканевых продуктов |
| US8834928B1 (en) | 2011-05-16 | 2014-09-16 | Musculoskeletal Transplant Foundation | Tissue-derived tissugenic implants, and methods of fabricating and using same |
| WO2012166668A1 (en) * | 2011-05-27 | 2012-12-06 | Christian Kazanecki | Bioartificial proximal tubule systems and methods of use |
| US20130143323A1 (en) * | 2011-06-01 | 2013-06-06 | Geoffrey S. FROST | Apparatus and method for decellularizing, recellularizing or treating organs |
| CA2838707C (en) * | 2011-06-06 | 2020-07-21 | Invivosciences, Inc. | Engineered cardiac tissues and methods of using them |
| WO2013028968A1 (en) * | 2011-08-25 | 2013-02-28 | Wisconsin Alumni Research Foundation | 3-dimensional cardiac fibroblast derived extracellular matrix |
| WO2013052138A2 (en) * | 2011-10-03 | 2013-04-11 | Fabrico. Inc. | System and method for electrophoretic decellularization |
| KR101360226B1 (ko) * | 2011-11-04 | 2014-02-12 | 강원대학교산학협력단 | 심폐 일체형 탈세포화기법 |
| US20140302480A1 (en) | 2011-11-09 | 2014-10-09 | The General Hospital Corporation | Composite tissue graft and materials and methods for its production and use |
| ES2833280T3 (es) | 2012-01-13 | 2021-06-14 | Massachusetts Gen Hospital | Células progenitoras pulmonares humanas aisladas y usos de las mismas |
| EP2809152B1 (en) | 2012-02-01 | 2019-11-20 | Nayacure Therapeutics Ltd | Method for inducing immune tolerance to organ transplants |
| CN104411816B (zh) | 2012-03-16 | 2018-01-02 | 诺瓦赫普有限公司 | 经生物工程改造的同种异体血管 |
| EP2838986A4 (en) * | 2012-04-18 | 2015-12-23 | Gen Hospital Corp | BIOARTIFICIAL FILTRATION ORGAN |
| EP2841010B1 (en) | 2012-04-24 | 2023-08-23 | Harvard Apparatus Regenerative Technology, Inc. | Supports for engineered tissue scaffolds |
| US20130344490A1 (en) * | 2012-04-27 | 2013-12-26 | Min Peter Kim | Neoplastic cells grown on decellularized biomatrix |
| US9290738B2 (en) * | 2012-06-13 | 2016-03-22 | Miromatrix Medical Inc. | Methods of decellularizing bone |
| GB201212771D0 (en) * | 2012-07-18 | 2012-08-29 | Northwick Park Inst For Medcal Res Ltd | Implant and method for producing an implant |
| US9297806B2 (en) * | 2012-08-01 | 2016-03-29 | The Johns Hopkins University | 5-hydroxymethylcytosine in human cancer |
| US10111740B2 (en) | 2012-08-21 | 2018-10-30 | Regents Of The University Of Minnesota | Decellularized biologically-engineered tubular grafts |
| WO2014058175A1 (ko) * | 2012-10-11 | 2014-04-17 | 강원대학교산학협력단 | 미산성 전해수를 유효성분으로 포함하는 바이오 스캐폴드 살균용 조성물 및 이를 이용한 바이오 스캐폴드의 살균 방법 |
| CA2890661A1 (en) * | 2012-11-07 | 2014-07-10 | James Bennie Gandy | Tissue transplantation involving, and tissues modified by decellularization and recellularization of donor tissues for minimized or obviated rejection reactions |
| HK1217663A1 (zh) | 2013-01-09 | 2017-01-20 | Harvard Apparatus Regenerative Technology, Inc. | 合成支架 |
| US10035980B2 (en) | 2013-01-14 | 2018-07-31 | Florida State University Research Foundation, Inc. | Extracellular matrix derived from stem cells and methods for production |
| CN103127550A (zh) * | 2013-02-26 | 2013-06-05 | 中国人民解放军第二军医大学 | 骨骼肌全器官脱细胞基质、制备方法及其衍生出的医疗产品 |
| EP2964154A4 (en) | 2013-03-07 | 2016-08-17 | Allosource | BONE ALLOTRANSPLATE SYSTEMS AND METHODS WITH CONSISTENT CALCIUM CONTENT |
| ES2831756T3 (es) | 2013-03-15 | 2021-06-09 | Miromatrix Medical Inc | Uso de hígado descelularizado por perfusión para la recelularización de células de islotes |
| US9888680B2 (en) * | 2013-04-04 | 2018-02-13 | The Trustees Of Columbia University In The City Of New York | Functional recovery of human lungs for transplantation |
| EP2983718A4 (en) * | 2013-04-11 | 2016-12-07 | Univ Of Vermont And State Agricultural College | Decellularization and recellularization of whole organs |
| AU2014250761B2 (en) * | 2013-04-12 | 2019-02-28 | Robert J. Deans | Improving organs for transplantation |
| GB201310773D0 (en) * | 2013-06-17 | 2013-07-31 | Northwick Park Inst For Medcal Res Ltd | Implant and method of producing an implant |
| US20150037436A1 (en) | 2013-07-30 | 2015-02-05 | Musculoskeletal Transplant Foundation | Acellular soft tissue-derived matrices and methods for preparing same |
| KR101636954B1 (ko) | 2013-11-04 | 2016-07-08 | 대한민국 | 재세포화된 바이오 스캐폴드 및 이의 제조방법 |
| JP6524597B2 (ja) | 2013-11-04 | 2019-06-05 | ライフセル コーポレーションLifeCell Corporation | α−ガラクトースを除去する方法 |
| WO2015081226A1 (en) | 2013-11-27 | 2015-06-04 | The Johns Hopkins University | Engineered cardiac derived compositions and methods of use |
| CN103736150B (zh) * | 2013-12-31 | 2015-11-18 | 中山大学 | 褪黑素协同细胞外基质生物材料在制备促进间充质干细胞成骨分化药物中的应用 |
| CN103750905B (zh) * | 2014-01-20 | 2015-08-12 | 辽宁中医药大学 | 大动物离体工作心双通道灌流实验方法及设备 |
| US11648335B2 (en) | 2014-01-31 | 2023-05-16 | Wake Forest University Health Sciences | Organ/tissue decellularization, framework maintenance and recellularization |
| JP6271299B2 (ja) * | 2014-02-28 | 2018-01-31 | 株式会社Adeka | 脱細胞組織の製造方法 |
| JP6271298B2 (ja) * | 2014-02-28 | 2018-01-31 | 国立大学法人 東京医科歯科大学 | 脱細胞組織の製造方法 |
| US10918102B2 (en) | 2014-03-13 | 2021-02-16 | The General Hospital Corporation | Devices and methods to improve and assess viability of human livers |
| CA2942714C (en) * | 2014-03-14 | 2023-09-05 | The General Hospital Corporation | Lung bioreactor |
| CN104940997A (zh) * | 2014-03-27 | 2015-09-30 | 复旦大学 | 一种组织工程化人类心肌组织 |
| JP6580329B2 (ja) | 2014-03-31 | 2019-09-25 | シスメックス株式会社 | 未分化細胞から分化細胞および/または分化細胞の産生物を取得する方法 |
| WO2015168528A1 (en) * | 2014-05-02 | 2015-11-05 | University Of Houston System | Two stage cellularization strategy for the fabrication of bioartificial hearts |
| AU2015265954A1 (en) * | 2014-05-27 | 2017-01-12 | Novahep Ab | Bioengineered allogeneic valve |
| GB201409858D0 (en) * | 2014-06-03 | 2014-07-16 | Ucl Business Plc | Human liver scaffolds |
| CN104208751A (zh) * | 2014-08-19 | 2014-12-17 | 温州医科大学 | 一种新型肾脏去细胞生物支架的制备方法 |
| WO2016036764A2 (en) * | 2014-09-02 | 2016-03-10 | United Therapeutics Corporation | Automated bioreactor system, system for automatically implementing protocol for decellularizing organ, and waste decontamination system |
| KR101693831B1 (ko) * | 2014-09-03 | 2017-01-17 | 서울대학교산학협력단 | 스페이스 필러를 이용한 이종이식조직의 제조방법 |
| EP3006557A1 (en) | 2014-10-07 | 2016-04-13 | Heinrich-Heine-Universität Düsseldorf | Bile acids for inducing hepatic differentiation |
| CA2966431C (en) | 2014-10-31 | 2023-02-14 | The Administrators Of The Tulane Educational Fund | Surgical grafts for replacing the nipple and areola or damaged epidermis |
| CN104740684A (zh) * | 2015-03-03 | 2015-07-01 | 上海市闸北区中心医院 | 一种犬子宫全器官脱细胞基质及其制备方法和应用 |
| SG11201707924VA (en) | 2015-03-26 | 2017-10-30 | Miromatrix Medical Inc | Gas filled decellularized extracellular matrix |
| JP2016185115A (ja) | 2015-03-27 | 2016-10-27 | シスメックス株式会社 | 臓器灌流方法および臓器灌流装置 |
| EP3297694A1 (en) | 2015-05-21 | 2018-03-28 | Musculoskeletal Transplant Foundation | Modified demineralized cortical bone fibers |
| RU2586952C1 (ru) * | 2015-07-20 | 2016-06-10 | Федеральное государственное бюджетное учреждение "Федеральный научный центр трансплантологии и искусственных органов имени академика В.И. Шумакова" Министерства здравоохранения Российской Федерации | Способ лечения печеночной недостаточности |
| US10912864B2 (en) | 2015-07-24 | 2021-02-09 | Musculoskeletal Transplant Foundation | Acellular soft tissue-derived matrices and methods for preparing same |
| CN105013014A (zh) * | 2015-07-31 | 2015-11-04 | 武汉蓝普医品有限公司 | 一种无细胞基质生物材料的制备方法和用途 |
| CN105031731B (zh) * | 2015-08-18 | 2018-04-17 | 温州医科大学 | 一种快速去细胞单叶肝脏生物支架的制备方法 |
| US11052175B2 (en) | 2015-08-19 | 2021-07-06 | Musculoskeletal Transplant Foundation | Cartilage-derived implants and methods of making and using same |
| ES2749160T3 (es) | 2015-09-11 | 2020-03-19 | Massachusetts Gen Hospital | Regeneración de un lecho vascular pulmonar funcional |
| NZ741377A (en) | 2015-10-09 | 2022-02-25 | Deka Products Lp | Fluid pumping and bioreactor system |
| EP3184128B1 (en) * | 2015-12-21 | 2019-12-11 | Heinrich-Heine-Universität Düsseldorf | Method for producing a support device |
| KR101860798B1 (ko) * | 2015-12-29 | 2018-05-25 | 포항공과대학교 산학협력단 | 뇌 조직 탈세포 방법 및 뇌 조직 배양 방법 |
| WO2017176919A1 (en) | 2016-04-05 | 2017-10-12 | Regents Of The University Of Minnesota | Engineered tissues having structural components embedded therein, and methods of making and using |
| EP3458076A4 (en) * | 2016-05-16 | 2020-01-22 | The General Hospital Corporation | HUMAN RESPIRATORY STEM CELLS IN BREEDING LUNG EPITHEL |
| US10624992B2 (en) | 2016-05-16 | 2020-04-21 | The General Hospital Corporation | Human airway stem cells in lung epithelial engineering |
| US11634448B2 (en) | 2016-06-15 | 2023-04-25 | The General Hospital Corporation | Metabolic labeling and molecular enhancement of biological materials using bioorthogonal reactions |
| CN106075583B (zh) * | 2016-07-07 | 2020-07-14 | 中国人民解放军第二军医大学 | 一种采用灌注-压差法制备脱细胞基质生物材料的方法 |
| US20190232232A1 (en) | 2016-07-14 | 2019-08-01 | Qidni Labs, Inc. | Biocompatible and hemocompatible material and filter |
| RU2639404C1 (ru) * | 2016-08-24 | 2017-12-21 | Государственное автономное учреждение здравоохранения Свердловской области "Центр специализированных видов медицинской помощи "Институт медицинских клеточных технологий" | Способ восстановления лимфоидной ткани селезенки лабораторных животных |
| EP3509651B1 (en) | 2016-09-06 | 2022-12-28 | Miromatrix Medical Inc. | Use of resected liver serum for whole liver engineering |
| FR3055805B1 (fr) | 2016-09-09 | 2020-05-15 | Assistance Publique - Hopitaux De Paris (Ap-Hp) | Biomateriau a usage therapeutique |
| US11299705B2 (en) | 2016-11-07 | 2022-04-12 | Deka Products Limited Partnership | System and method for creating tissue |
| CN115400268A (zh) | 2017-01-30 | 2022-11-29 | 生命细胞公司 | 组织基质材料和酶粘合剂 |
| CN111544652A (zh) | 2017-01-30 | 2020-08-18 | 生命细胞公司 | 转谷氨酰胺酶处理的产品 |
| CN107096070B (zh) * | 2017-03-09 | 2020-08-21 | 中国医学科学院阜外医院 | 一种脱细胞肺支架及其制备方法 |
| RU2665962C1 (ru) | 2017-03-17 | 2018-09-05 | Общество с ограниченной ответственностью "Матрифлекс" | Биорезорбируемый биологический матрикс для замещения дефектов костной ткани и способ его получения |
| US10767164B2 (en) | 2017-03-30 | 2020-09-08 | The Research Foundation For The State University Of New York | Microenvironments for self-assembly of islet organoids from stem cells differentiation |
| CN107137769A (zh) * | 2017-06-06 | 2017-09-08 | 中国人民解放军军事医学科学院基础医学研究所 | 一种心脏全器官脱细胞基质的制备方法 |
| US12058996B2 (en) | 2017-06-14 | 2024-08-13 | The General Hospital Corporation | High subzero cryopreservation |
| EP3685661A4 (en) * | 2017-09-19 | 2021-05-19 | Meiji University | PROCESS FOR DEVELOPMENT OF AN ORGAN LACKING A SPECIFIC FUNCTIONAL CELL |
| US12070530B2 (en) | 2017-11-09 | 2024-08-27 | University of Pittsburgh—of the Commonwealth System of Higher Education | Decellularization and functionalization of extracellular matrix biomaterials |
| JP7174984B2 (ja) * | 2018-02-15 | 2022-11-18 | 学校法人自治医科大学 | 脱細胞化担体製造方法、脱細胞化担体保存方法、細胞充填方法、細胞シート作製方法、及び脱細胞化溶液キット |
| GB201807788D0 (en) * | 2018-05-14 | 2018-06-27 | Ucl Business Plc | Method |
| US12167729B2 (en) | 2018-05-30 | 2024-12-17 | The General Hospital Corporation | Cryopreservation of tissues and organs |
| WO2019241499A1 (en) | 2018-06-13 | 2019-12-19 | Miromatrix Medical Inc. | Fistula filler and deployment system |
| TWI712687B (zh) * | 2018-09-11 | 2020-12-11 | 亞果生醫股份有限公司 | 去細胞器官及其製備方法 |
| WO2020191374A1 (en) * | 2019-03-21 | 2020-09-24 | Miromatrix Medical Inc. | Improved decellularization of isolated organs |
| EP3975936A4 (en) | 2019-05-28 | 2022-08-03 | Regents of the University of Minnesota | ENGINEERING VALVE AND METHOD OF MANUFACTURE |
| CN110694113B (zh) * | 2019-10-15 | 2022-02-01 | 南通大学附属医院 | 一种脑脱细胞支架的制备方法 |
| US20230015009A1 (en) * | 2019-12-04 | 2023-01-19 | Miromatrix Medical Inc. | Methods of Decellularization and Recellularization of Organs and Portions of Organs |
| JP2023520621A (ja) * | 2020-02-14 | 2023-05-18 | セルアートジェン インコーポレイテッド | 心臓オルガノイド培養及び移植のための脱細胞心臓組織由来支持体及びその製造方法 |
| CN115516080A (zh) * | 2020-02-14 | 2022-12-23 | 赛拉尔研究有限公司 | 用于培养和移植器官类器官的脱细胞器官组织衍生支架及其制造方法 |
| CN111494718B (zh) * | 2020-04-24 | 2021-05-14 | 四川大学华西医院 | 一种动物去细胞化肺生物支架材料的制备方法 |
| KR102473682B1 (ko) * | 2020-06-30 | 2022-12-02 | 서울대학교 산학협력단 | 개인 맞춤형 경피적 심장 반월판 스텐트 판막의 제조 방법 |
| CN112354014A (zh) * | 2020-10-20 | 2021-02-12 | 上海亚朋生物技术有限公司 | 一种清洗脱细胞试剂sds的方法 |
| CN112274697A (zh) * | 2020-11-04 | 2021-01-29 | 王寅 | 一种组织工程心肌补片制备方法 |
| US11998662B1 (en) | 2021-06-09 | 2024-06-04 | Reprise Biomedical, Inc. | Biologic matrix for a wound site and related methods |
| US12383657B1 (en) | 2021-06-09 | 2025-08-12 | Reprise Biomedical, Inc. | Biologic matrix for a wound site and related methods |
| DE102021211875B3 (de) * | 2021-10-21 | 2023-01-19 | Friedrich-Alexander-Universität Erlangen-Nürnberg, Körperschaft des öffentlichen Rechts | Bioreaktor und Verfahren zum Betrieb eines solchen |
| WO2024006673A1 (en) * | 2022-06-30 | 2024-01-04 | Regenmedix Llc | Stem cell and organ maturation system and method |
| CN115554472B (zh) * | 2022-09-22 | 2023-08-18 | 舩本诚一 | 一种用于移植的生物组织处理方法 |
| CN120548201A (zh) | 2022-11-18 | 2025-08-26 | 万益特健康有限责任公司 | 用于器官支持的体外血液处理 |
Family Cites Families (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3545221A (en) | 1967-05-22 | 1970-12-08 | Swenko Research & Dev Inc | Apparatus for maintaining organs in vitro in a completely viable state |
| US3639084A (en) | 1970-04-06 | 1972-02-01 | Baxter Laboratories Inc | Mechanism for control pulsatile fluid flow |
| DE2453363B2 (de) | 1974-11-11 | 1976-08-26 | Solco Basel AG, Birsfelden (Schweiz) | Verfahren zur herstellung heterologer arterientransplantate |
| JPS5516016A (en) | 1978-07-18 | 1980-02-04 | Dai Ichi Kogyo Seiyaku Co Ltd | Improved salt-resistant water-absorbing material |
| US4801299A (en) | 1983-06-10 | 1989-01-31 | University Patents, Inc. | Body implants of extracellular matrix and means and methods of making and using such implants |
| US5336616A (en) | 1990-09-12 | 1994-08-09 | Lifecell Corporation | Method for processing and preserving collagen-based tissues for transplantation |
| CA2199810A1 (en) | 1994-09-12 | 1996-03-21 | Gail K. Naughton | Three-dimensional human cell cultures on cardiac valve frameworks and their uses |
| EP0987998B1 (en) * | 1997-04-11 | 2004-10-13 | CryoLife, Inc. | Tissue decellularization |
| JPH1176400A (ja) | 1997-09-09 | 1999-03-23 | Masahito Nagaki | 人工臓器 |
| JP4222658B2 (ja) | 1998-06-23 | 2009-02-12 | テルモ株式会社 | 細胞支持基材、培養装置および液体処理装置 |
| US6734018B2 (en) * | 1999-06-07 | 2004-05-11 | Lifenet | Process for decellularizing soft-tissue engineered medical implants, and decellularized soft-tissue medical implants produced |
| US6448076B2 (en) * | 1998-09-15 | 2002-09-10 | The Regents Of The University Of Michigan | Method for chemically acellularizing a biological tissue sample |
| US6432712B1 (en) * | 1999-11-22 | 2002-08-13 | Bioscience Consultants, Llc | Transplantable recellularized and reendothelialized vascular tissue graft |
| US6376244B1 (en) | 1999-12-29 | 2002-04-23 | Children's Medical Center Corporation | Methods and compositions for organ decellularization |
| US20050249816A1 (en) | 1999-12-29 | 2005-11-10 | Wake Forest University Health Services | Tissue engineered liver constructs |
| US6479064B1 (en) | 1999-12-29 | 2002-11-12 | Children's Medical Center Corporation | Culturing different cell populations on a decellularized natural biostructure for organ reconstruction |
| AU2001255741B2 (en) * | 2000-04-28 | 2005-08-04 | Baylor College Of Medicine | Decellularized vascular prostheses |
| DE10021627B4 (de) | 2000-05-04 | 2009-11-19 | Corlife Gbr (Vertretungsberechtigte Gesellschafter: Prof. Dr. Alex Haverich | Verfahren zur Herstellung eines vaskularisierten bioartifiziellen Gewebes und zugehöriger Versuchsreaktor |
| AU2001284968B2 (en) | 2000-08-16 | 2006-12-21 | Duke University | Decellularized tissue engineered constructs and tissues |
| US6749064B1 (en) | 2000-08-25 | 2004-06-15 | Sanita L. Alrey | Bag with article display aperture and support surface |
| WO2002024244A2 (en) | 2000-09-20 | 2002-03-28 | Regeneration Technologies, Inc. | Method of preparing and processing transplant tissue |
| IL139708A0 (en) | 2000-11-15 | 2002-02-10 | Amiel Gilad | Process of decellularizing biological matrices and acellular biological matrices useful in tissue engineering |
| DE10064948C1 (de) | 2000-12-20 | 2002-07-11 | Auto Tissue Gmbh | Verfahren zur Dezellularisierung von Fremdmaterial zur Herstellung von Bioprothesen und Vorrichtung zur Durchführung des Verfahrens |
| NZ528035A (en) | 2001-02-14 | 2005-07-29 | Robert J Hariri | Renovation and repopulation of decellularized tissues and cadaveric organs by stem cells |
| WO2002088331A1 (en) | 2001-05-01 | 2002-11-07 | Universite Du Quebec A Montreal | Tridimensional biocompatible support structure for bioartificial organs and uses thereof |
| GB2375771A (en) | 2001-05-24 | 2002-11-27 | Univ Leeds | Decellularisation of tissue implant material |
| EP1317934A1 (de) * | 2001-11-08 | 2003-06-11 | Artiss GmbH | Verfahren zur Herstellung einer azellularisierten Gewebematrix und damit erhältliche Gewebematrix |
| EP1448247B1 (en) | 2001-11-16 | 2011-02-16 | Children's Medical Center Corporation | Creation of tissue engineered female reproductive organs |
| EP1446171A1 (en) | 2001-11-16 | 2004-08-18 | Children's Medical Center Corporation | Augmentation of organ function |
| US20030180268A1 (en) | 2002-02-05 | 2003-09-25 | Anthony Atala | Tissue engineered construct for supplementing or replacing a damaged organ |
| US6790475B2 (en) | 2002-04-09 | 2004-09-14 | Wafermasters Inc. | Source gas delivery |
| JP4149897B2 (ja) | 2002-11-07 | 2008-09-17 | 学校法人 聖マリアンナ医科大学 | 気管移植片の調製方法および気管移植片 |
| US20040187877A1 (en) | 2002-12-04 | 2004-09-30 | Badylak Stephen F. | Method for repair of liver tissue |
| TW200427448A (en) | 2002-12-13 | 2004-12-16 | Cilag Ag | Controlled release preparations comprising tramadol and topiramate |
| US20040176855A1 (en) | 2003-03-07 | 2004-09-09 | Acell, Inc. | Decellularized liver for repair of tissue and treatment of organ deficiency |
| JP2006223101A (ja) * | 2003-05-15 | 2006-08-31 | Univ Waseda | 生体組織の保持装置及びこれを用いた生体組織処理装置 |
| WO2005118014A2 (en) * | 2004-06-01 | 2005-12-15 | Medtronic, Inc. | Decellurisation processes for making bioprotheses |
| JP3773943B2 (ja) | 2004-09-24 | 2006-05-10 | 国立大学法人 東京大学 | 把持状態判定システム及び方法 |
| DE102005023599A1 (de) | 2005-05-18 | 2006-11-23 | Corlife Gbr (Vertretungsberechtigte Gesellschafter: Prof. Dr. Alex Haverich | Bioartifizielles Herzgewebetransplantat und Verfahren zu seiner Herstellung |
| WO2006126219A1 (en) | 2005-05-26 | 2006-11-30 | Fresenius Medical Care Deutschland G.M.B.H. | Liver progenitor cells |
| WO2007002228A1 (en) | 2005-06-23 | 2007-01-04 | Massachusetts Institute Of Technology | Methods for ex vivo propagation of adult hepatic stem cells |
| ES2384721T3 (es) | 2005-08-26 | 2012-07-11 | Regents Of The University Of Minnesota | Descelularización y recelularización de órganos y tejidos |
| US20100093066A1 (en) | 2005-08-26 | 2010-04-15 | Regents Of The University Of Minnesota | Decellularization and recellularization apparatuses and systems containing the same |
| AU2013224686B2 (en) | 2005-08-26 | 2015-06-11 | Miromatrix Medical Inc. | Decellularization and recellularization of organs and tissues |
| JP4599315B2 (ja) | 2006-02-23 | 2010-12-15 | クラレメディカル株式会社 | バイオ人工臓器 |
| CN101066477B (zh) | 2007-05-17 | 2010-10-06 | 中国人民解放军第三军医大学 | 能在体捕获内皮祖细胞的生物人工血管 |
| CA2743682A1 (en) | 2007-11-30 | 2009-06-11 | New York Medical College | Methods of reducing transplant rejection and cardiac allograft vasculopathy by implanting autologous stem cells |
| SG174969A1 (en) | 2009-03-31 | 2011-11-28 | Univ Minnesota | Decellularization and recellularization of organs and tissues |
| EP2588592B1 (en) | 2010-06-30 | 2017-09-06 | Miromatrix Medical Inc. | Use of perfusion decellularized organs for matched recellularization |
| SG188369A1 (en) | 2010-09-01 | 2013-04-30 | Univ Minnesota | Methods of recellularizing a tissue or organ for improved transplantability |
| US9290738B2 (en) | 2012-06-13 | 2016-03-22 | Miromatrix Medical Inc. | Methods of decellularizing bone |
| KR102417995B1 (ko) | 2013-03-15 | 2022-07-06 | 미로매트릭스 메디칼 인크. | 탈세포화된 기관 및 조직에 대한 마이크로입자 및 내피 세포의 용도 |
| ES2831756T3 (es) | 2013-03-15 | 2021-06-09 | Miromatrix Medical Inc | Uso de hígado descelularizado por perfusión para la recelularización de células de islotes |
| JP6340772B2 (ja) | 2013-11-08 | 2018-06-13 | 東ソー株式会社 | パラメータ変更履歴を管理可能な分析装置 |
| SG11201707924VA (en) | 2015-03-26 | 2017-10-30 | Miromatrix Medical Inc | Gas filled decellularized extracellular matrix |
| EP3509651B1 (en) | 2016-09-06 | 2022-12-28 | Miromatrix Medical Inc. | Use of resected liver serum for whole liver engineering |
-
2006
- 2006-08-28 ES ES06790024T patent/ES2384721T3/es active Active
- 2006-08-28 RU RU2008111503/14A patent/RU2463081C2/ru active
- 2006-08-28 EP EP06790024A patent/EP1928519B1/en active Active
- 2006-08-28 ES ES11181797.9T patent/ES2547139T3/es active Active
- 2006-08-28 AT AT06790024T patent/ATE552007T1/de active
- 2006-08-28 KR KR1020147007674A patent/KR20140040293A/ko not_active Ceased
- 2006-08-28 MX MX2017011107A patent/MX369594B/es unknown
- 2006-08-28 SG SG201101898-3A patent/SG170731A1/en unknown
- 2006-08-28 MX MX2008002589A patent/MX2008002589A/es active IP Right Grant
- 2006-08-28 US US12/064,613 patent/US8470520B2/en active Active
- 2006-08-28 AU AU2006282783A patent/AU2006282783B2/en active Active
- 2006-08-28 KR KR1020087007151A patent/KR101376013B1/ko active Active
- 2006-08-28 CN CN201210287455.7A patent/CN102861359B/zh active Active
- 2006-08-28 EP EP15170077.0A patent/EP2965769B1/en active Active
- 2006-08-28 JP JP2008528231A patent/JP2009505752A/ja active Pending
- 2006-08-28 EP EP11181797.9A patent/EP2431063B1/en active Active
- 2006-08-28 CN CN2006800309254A patent/CN101272815B/zh active Active
- 2006-08-28 PL PL11181797T patent/PL2431063T3/pl unknown
- 2006-08-28 CA CA2618731A patent/CA2618731C/en active Active
- 2006-08-28 WO PCT/US2006/033415 patent/WO2007025233A1/en not_active Ceased
- 2006-08-28 KR KR1020137028378A patent/KR101420585B1/ko active Active
- 2006-08-28 PL PL06790024T patent/PL1928519T3/pl unknown
- 2006-08-28 MX MX2014006778A patent/MX350338B/es unknown
-
2008
- 2008-02-11 IL IL189418A patent/IL189418A/en active IP Right Grant
-
2012
- 2012-05-28 RU RU2012122055A patent/RU2635478C9/ru active
- 2012-11-12 JP JP2012248398A patent/JP2013056183A/ja not_active Withdrawn
- 2012-12-21 US US13/725,030 patent/US10441609B2/en active Active
-
2013
- 2013-06-10 US US13/913,974 patent/US10220056B2/en active Active
-
2014
- 2014-07-27 IL IL233821A patent/IL233821A/en active IP Right Grant
-
2015
- 2015-05-07 JP JP2015094591A patent/JP6089062B2/ja active Active
-
2016
- 2016-10-13 JP JP2016201559A patent/JP2017038948A/ja not_active Withdrawn
-
2019
- 2019-01-11 US US16/245,435 patent/US20190343877A1/en not_active Abandoned
- 2019-02-25 JP JP2019031120A patent/JP2019088910A/ja not_active Withdrawn
- 2019-08-29 US US16/554,792 patent/US20200222456A1/en active Pending
-
2021
- 2021-05-14 JP JP2021082285A patent/JP7286708B2/ja active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2013056183A5 (enExample) | ||
| Tapias et al. | Decellularized scaffolds as a platform for bioengineered organs | |
| JP2022107023A (ja) | 臓器および組織を脱細胞化および再細胞化する方法 | |
| Zhao et al. | The role of tissue engineering and biomaterials in cardiac regenerative medicine | |
| RU2013114382A (ru) | Способы рецеллюляризации ткани или органа для улучшения приживления трансплантата | |
| Avolio et al. | Stem cell therapy and tissue engineering for correction of congenital heart disease | |
| RU2012122055A (ru) | Удаление и восстановление содержания клеток в органах и тканях | |
| JP2007528755A (ja) | 三次元組織構造体 | |
| Ghorbel et al. | Reconstruction of the pulmonary artery by a novel biodegradable conduit engineered with perinatal stem cell-derived vascular smooth muscle cells enables physiological vascular growth in a large animal model of congenital heart disease | |
| Moran et al. | Whole-organ bioengineering: current tales of modern alchemy | |
| EP2775957A1 (en) | Composite tissue graft and materials and methods for its production and use | |
| Mao et al. | Sustained in vivo perfusion of a re-endothelialized tissue engineered porcine liver | |
| ES2699690T3 (es) | Dispositivos prevascularizados y métodos relacionados | |
| Thai et al. | Implantation of a three-dimensional fibroblast matrix improves left ventricular function and blood flow after acute myocardial infarction | |
| Premaratne et al. | Repeated implantation is a more effective cell delivery method in skeletal myoblast transplantation for rat myocardial infarction | |
| Roche et al. | Transplantation of a 3D bioprinted patch in a murine model of myocardial infarction. | |
| Chachques | Development of bioartificial myocardium using stem cells and nanobiotechnology templates | |
| JP2005278711A (ja) | ハニカムフィルムを用いた機能的人工組織の生産 | |
| US20230174942A1 (en) | Novel fabrication of coronary based decellularized heart flaps to treat aneurysm following myocardial infarction | |
| Alkan et al. | Regenerative stem cell therapy optimization via tissue engineering in heart failure with reduced ejection fraction | |
| Zeng et al. | Strategies of bladder reconstruction after partial or radical cystectomy for bladder cancer | |
| Ding et al. | The Applications of the Recellularization Organs in Organ Replacement at the Stage of Animal Research | |
| Kim et al. | A long road for stem cells to cure sick hearts: update on recent clinical trials | |
| Krane et al. | Promises and pitfalls in cell replacement therapy for heart failure | |
| US9962410B2 (en) | Compositions and methods related to organ or tissue decellularization |