JP2012518421A5 - - Google Patents
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- Publication number
- JP2012518421A5 JP2012518421A5 JP2011551323A JP2011551323A JP2012518421A5 JP 2012518421 A5 JP2012518421 A5 JP 2012518421A5 JP 2011551323 A JP2011551323 A JP 2011551323A JP 2011551323 A JP2011551323 A JP 2011551323A JP 2012518421 A5 JP2012518421 A5 JP 2012518421A5
- Authority
- JP
- Japan
- Prior art keywords
- target rna
- level
- sequence
- seq
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108091032973 (ribonucleotides)n+m Proteins 0.000 claims 28
- 238000000034 method Methods 0.000 claims 20
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 8
- 201000005202 lung cancer Diseases 0.000 claims 8
- 208000020816 lung neoplasm Diseases 0.000 claims 8
- 108020004707 nucleic acids Proteins 0.000 claims 8
- 102000039446 nucleic acids Human genes 0.000 claims 8
- 150000007523 nucleic acids Chemical class 0.000 claims 8
- 230000000295 complement effect Effects 0.000 claims 7
- 238000001514 detection method Methods 0.000 claims 7
- 239000002773 nucleotide Substances 0.000 claims 6
- 125000003729 nucleotide group Chemical group 0.000 claims 6
- 210000004072 lung Anatomy 0.000 claims 2
- 108091033319 polynucleotide Proteins 0.000 claims 2
- 102000040430 polynucleotide Human genes 0.000 claims 2
- 239000002157 polynucleotide Substances 0.000 claims 2
- 102000040650 (ribonucleotides)n+m Human genes 0.000 claims 1
- 108091093088 Amplicon Proteins 0.000 claims 1
- 108020004414 DNA Proteins 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 238000013276 bronchoscopy Methods 0.000 claims 1
- 210000005265 lung cell Anatomy 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15536409P | 2009-02-25 | 2009-02-25 | |
| US61/155,364 | 2009-02-25 | ||
| PCT/US2010/025446 WO2010099342A2 (en) | 2009-02-25 | 2010-02-25 | Methods of detecting lung cancer |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012518421A JP2012518421A (ja) | 2012-08-16 |
| JP2012518421A5 true JP2012518421A5 (enExample) | 2013-04-18 |
| JP5755569B2 JP5755569B2 (ja) | 2015-07-29 |
Family
ID=42666217
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011551323A Expired - Fee Related JP5755569B2 (ja) | 2009-02-25 | 2010-02-25 | 肺癌を検出する方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (4) | US20100233704A1 (enExample) |
| EP (2) | EP2628803A3 (enExample) |
| JP (1) | JP5755569B2 (enExample) |
| CA (1) | CA2753481A1 (enExample) |
| WO (1) | WO2010099342A2 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006039293A2 (en) * | 2004-09-29 | 2006-04-13 | University Of Virginia Patent Foundation | Localized control of thermal properties on microdevices and applications thereof |
| US8056881B2 (en) | 2004-10-13 | 2011-11-15 | University Of Virginia Patent Foundation | Electrostatic actuation for management of flow in micro-total analysis systems (μ-TAS) and related method thereof |
| WO2006069305A2 (en) * | 2004-12-22 | 2006-06-29 | University Of Virginia Patent Foundation | The use of microwaves for thermal and non-thermal applications in micro and nanoscale devices |
| US8343755B2 (en) * | 2005-08-01 | 2013-01-01 | University Of Virginia Patent Foundation | Microdevices for chemical sensing and chemical actuation |
| CA2620285C (en) * | 2005-08-23 | 2016-08-16 | University Of Virginia Patent Foundation | Passive components for micro-fluidic flow profile shaping and related method thereof |
| US20110033922A1 (en) * | 2005-10-04 | 2011-02-10 | Landers James P | Microchip-based acoustic trapping or capture of cells for forensic analysis and related method thereof |
| US8916375B2 (en) * | 2005-10-12 | 2014-12-23 | University Of Virginia Patent Foundation | Integrated microfluidic analysis systems |
| US20100240049A1 (en) | 2009-01-16 | 2010-09-23 | Cepheid | Methods of Detecting Cervical Cancer |
| AU2010207975B2 (en) * | 2009-02-02 | 2016-04-28 | Cepheid | Methods of detecting sepsis |
| WO2010099161A1 (en) * | 2009-02-26 | 2010-09-02 | The Ohio State University Research Foundation | Micrornas in never-smokers and related materials and methods |
| US20110105585A1 (en) * | 2009-04-23 | 2011-05-05 | Northwestern University | METHODS FOR DIAGNOSING AND TREATING SQUAMOUS CELL CARCINOMA UTILIZING miRNA-205 AND INHIBITORS THEREOF |
| US8691504B2 (en) * | 2009-05-26 | 2014-04-08 | Xiamen University | Method for detecting variations in nucleic acid sequences |
| US8911940B2 (en) | 2009-07-31 | 2014-12-16 | The Translational Genomics Research Institute | Methods of assessing a risk of cancer progression |
| AU2012211272A1 (en) * | 2011-01-26 | 2013-08-15 | Cepheid | Methods of detecting lung cancer |
| WO2012163541A1 (en) * | 2011-06-01 | 2012-12-06 | Medical Prognosis Institute A/S | Methods and devices for prognosis of cancer relapse |
| WO2013143940A1 (en) * | 2012-03-29 | 2013-10-03 | Proyecto De Biomedicina Cima, S.L. | New lung cancer molecular markers |
| ES2843202T3 (es) | 2012-09-28 | 2021-07-16 | Cepheid | Métodos para la extracción de ADN y ARN a partir de muestras de tejido fijado embebido en parafina |
| WO2014093360A1 (en) | 2012-12-10 | 2014-06-19 | Landers James P | Frequency-based filtering of mechanical actuation using fluidic device |
| WO2014159073A1 (en) * | 2013-03-14 | 2014-10-02 | Cepheid | Methods of detecting lung cancer |
| KR102511402B1 (ko) * | 2014-06-18 | 2023-03-17 | 국립연구개발법인 고쿠리츠간켄큐센터 | 폐암의 검출 키트 또는 디바이스 및 검출 방법 |
| US20180208957A1 (en) * | 2015-04-30 | 2018-07-26 | Curevac Ag | Method for in vitro transcription using an immobilized restriction enzyme |
| DK3325647T3 (da) | 2015-07-24 | 2020-05-18 | Cepheid | Sammensætninger og fremgangsmåder til dna- og rna-ekstraktion fra vævsprøver |
| US11584932B2 (en) | 2016-11-01 | 2023-02-21 | The Research Foundation For The State University Of New York | 5-halouracil-modified microRNAs and their use in the treatment of cancer |
| KR20250006333A (ko) | 2017-06-29 | 2025-01-10 | 도레이 카부시키가이샤 | 폐암의 검출을 위한 키트, 디바이스 및 방법 |
| KR20220004696A (ko) * | 2019-04-30 | 2022-01-11 | 더 트러스티스 오브 더 유니버시티 오브 펜실베니아 | 폼페병의 치료에 유용한 조성물 |
| CN115786511A (zh) * | 2022-11-08 | 2023-03-14 | 浙江大学 | 小核酸组合作为生物标志物在制备诊断肺癌和/或评估肺癌预后的试剂或者试剂盒中的应用 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1978110B1 (en) * | 2000-09-06 | 2010-05-26 | Transnetyx, Inc. | Computer-based method and system for screening genomic DNA |
| US6706867B1 (en) * | 2000-12-19 | 2004-03-16 | The United States Of America As Represented By The Department Of Health And Human Services | DNA array sequence selection |
| WO2004047757A2 (en) * | 2002-11-21 | 2004-06-10 | University Of Massachusets | Diagnosing and treating hematopoietic cancers |
| EP2322650A1 (en) * | 2004-05-14 | 2011-05-18 | Rosetta Genomics Ltd | MicroRNAs and uses thereof |
| FR2873625B1 (fr) | 2004-08-02 | 2008-05-30 | Michelin Soc Tech | Assemblage pneu/roue pourvu d'une composition lubrifiante |
| US7351538B2 (en) | 2004-08-23 | 2008-04-01 | U.S. Genomics | Systems and methods for detecting and analyzing polymers |
| US20060094025A1 (en) | 2004-11-02 | 2006-05-04 | Getts Robert C | Methods for detection of microrna molecules |
| US20060134663A1 (en) * | 2004-11-03 | 2006-06-22 | Paul Harkin | Transcriptome microarray technology and methods of using the same |
| DE602006016739D1 (de) | 2005-01-25 | 2010-10-21 | Rosetta Inpharmatics Llc | Verfahren zur quantifizierung kleiner rna-moleküle |
| JP2008538494A (ja) * | 2005-04-07 | 2008-10-30 | ザ クリーブランド クリニック ファウンデーション | 癌と関連するガンマレトロウイルス |
| US20070077570A1 (en) | 2005-05-31 | 2007-04-05 | Applera Corporation | Multiplexed amplification of short nucleic acids |
| US20070054287A1 (en) | 2005-05-31 | 2007-03-08 | Applera Corporation | Method for identifying medically important cell populations using micro rna as tissue specific biomarkers |
| US20070065844A1 (en) * | 2005-06-08 | 2007-03-22 | Massachusetts Institute Of Technology | Solution-based methods for RNA expression profiling |
| US20060292616A1 (en) | 2005-06-23 | 2006-12-28 | U.S. Genomics, Inc. | Single molecule miRNA-based disease diagnostic methods |
| EP2308990B1 (en) | 2005-07-15 | 2012-09-26 | Life Technologies Corporation | Analyzing messenger RNA and micro RNA in the same reaction mixture |
| ATE532878T1 (de) | 2005-08-24 | 2011-11-15 | Life Technologies Corp | Verfahren zur quantifizierung von sirnas, mirnas und polymorphen mirnas |
| EP1783645A1 (en) * | 2005-11-08 | 2007-05-09 | Actigenics | Methods for the identification of microRNA and their applications in research and human health |
| WO2007078697A1 (en) * | 2005-12-29 | 2007-07-12 | Dow Global Technologies Inc. | Low molecular weight ethylene interpolymers, methods of making, and uses thereof |
| EP2487261B1 (en) * | 2006-01-05 | 2015-07-01 | The Ohio State University Research Foundation | MicroRNA-based methods and compositions for the diagnosis and treatment of solid cancers |
| ES2429404T3 (es) * | 2006-01-05 | 2013-11-14 | The Ohio State University Research Foundation | Procedimientos basados en los microARN para el diagnóstico y el pronóstico del cáncer de pulmón |
| DK2205737T3 (da) * | 2007-10-04 | 2013-05-21 | Santaris Pharma As | Mikromirer |
| EP2336353A1 (en) * | 2009-12-17 | 2011-06-22 | febit holding GmbH | miRNA fingerprints in the diagnosis of diseases |
-
2010
- 2010-02-25 EP EP13159760.1A patent/EP2628803A3/en not_active Withdrawn
- 2010-02-25 EP EP10746849A patent/EP2401406A4/en not_active Withdrawn
- 2010-02-25 WO PCT/US2010/025446 patent/WO2010099342A2/en not_active Ceased
- 2010-02-25 CA CA2753481A patent/CA2753481A1/en not_active Abandoned
- 2010-02-25 US US12/713,072 patent/US20100233704A1/en not_active Abandoned
- 2010-02-25 JP JP2011551323A patent/JP5755569B2/ja not_active Expired - Fee Related
-
2012
- 2012-11-26 US US13/684,874 patent/US20130157886A1/en not_active Abandoned
-
2013
- 2013-11-14 US US14/079,741 patent/US20140200153A1/en not_active Abandoned
-
2015
- 2015-05-26 US US14/721,098 patent/US20150376711A1/en not_active Abandoned
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