JP2015091235A5 - - Google Patents

Info

Publication number

JP2015091235A5

JP2015091235A5 JP2014237731A JP2014237731A JP2015091235A5 JP 2015091235 A5 JP2015091235 A5 JP 2015091235A5 JP 2014237731 A JP2014237731 A JP 2014237731A JP 2014237731 A JP2014237731 A JP 2014237731A JP 2015091235 A5 JP2015091235 A5 JP 2015091235A5

Authority

JP

Japan

Prior art keywords

polynucleotide

ros fusion

sample

lung cancer

biological sample

Prior art date

2014-11-25

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
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• 230000004927 fusion Effects 0.000 claims 14
• 238000000034 method Methods 0.000 claims 13
• 108091033319 polynucleotide Proteins 0.000 claims 13
• 102000040430 polynucleotide Human genes 0.000 claims 13
• 239000002157 polynucleotide Substances 0.000 claims 13
• 208000002154 non-small cell lung carcinoma Diseases 0.000 claims 7
• 239000000523 sample Substances 0.000 claims 7
• 206010028980 Neoplasm Diseases 0.000 claims 6
• 239000012472 biological sample Substances 0.000 claims 6
• 208000029729 tumor suppressor gene on chromosome 11 Diseases 0.000 claims 6
• 239000002773 nucleotide Substances 0.000 claims 5
• 125000003729 nucleotide group Chemical group 0.000 claims 5
• 206010058467 Lung neoplasm malignant Diseases 0.000 claims 4
• 201000011510 cancer Diseases 0.000 claims 4
• 201000005202 lung cancer Diseases 0.000 claims 4
• 208000020816 lung neoplasm Diseases 0.000 claims 4
• 229920001184 polypeptide Polymers 0.000 claims 4
• 102000004196 processed proteins & peptides Human genes 0.000 claims 4
• 108090000765 processed proteins & peptides Proteins 0.000 claims 4
• 238000001514 detection method Methods 0.000 claims 3
• 208000002151 Pleural effusion Diseases 0.000 claims 2
• 125000003275 alpha amino acid group Chemical group 0.000 claims 2
• 230000003321 amplification Effects 0.000 claims 2
• 238000001574 biopsy Methods 0.000 claims 2
• 239000008280 blood Substances 0.000 claims 2
• 210000004369 blood Anatomy 0.000 claims 2
• 230000000295 complement effect Effects 0.000 claims 2
• 238000003199 nucleic acid amplification method Methods 0.000 claims 2
• 238000012163 sequencing technique Methods 0.000 claims 2
• -1 small molecule compound Chemical class 0.000 claims 2
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
• 108020004711 Nucleic Acid Probes Proteins 0.000 claims 1
• 239000003814 drug Substances 0.000 claims 1
• 230000000694 effects Effects 0.000 claims 1
• 238000012295 fluorescence in situ hybridization assay Methods 0.000 claims 1
• 239000002853 nucleic acid probe Substances 0.000 claims 1
• 102000039446 nucleic acids Human genes 0.000 claims 1
• 108020004707 nucleic acids Proteins 0.000 claims 1
• 150000007523 nucleic acids Chemical class 0.000 claims 1