JP2013500713A5 - - Google Patents
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- Publication number
- JP2013500713A5 JP2013500713A5 JP2012522282A JP2012522282A JP2013500713A5 JP 2013500713 A5 JP2013500713 A5 JP 2013500713A5 JP 2012522282 A JP2012522282 A JP 2012522282A JP 2012522282 A JP2012522282 A JP 2012522282A JP 2013500713 A5 JP2013500713 A5 JP 2013500713A5
- Authority
- JP
- Japan
- Prior art keywords
- hepatitis
- subject
- infected
- involuntary
- polymorphic marker
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 11
- 208000005176 Hepatitis C Diseases 0.000 claims 10
- 239000003550 marker Substances 0.000 claims 6
- 150000007523 nucleic acids Chemical class 0.000 claims 4
- 102000039446 nucleic acids Human genes 0.000 claims 4
- 108020004707 nucleic acids Proteins 0.000 claims 4
- 239000012472 biological sample Substances 0.000 claims 3
- 239000000523 sample Substances 0.000 claims 3
- 101001002466 Homo sapiens Interferon lambda-3 Proteins 0.000 claims 2
- 102100020990 Interferon lambda-1 Human genes 0.000 claims 2
- 102100020992 Interferon lambda-3 Human genes 0.000 claims 2
- 239000003153 chemical reaction reagent Substances 0.000 claims 2
- 230000003612 virological effect Effects 0.000 claims 2
- 208000006154 Chronic hepatitis C Diseases 0.000 claims 1
- 241000700605 Viruses Species 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 208000010710 hepatitis C virus infection Diseases 0.000 claims 1
- 101150098466 rpsL gene Proteins 0.000 claims 1
- 230000035945 sensitivity Effects 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH01201/09 | 2009-07-31 | ||
| CH12012009 | 2009-07-31 | ||
| US28253810P | 2010-02-26 | 2010-02-26 | |
| US61/282,538 | 2010-02-26 | ||
| PCT/IB2010/053139 WO2011013019A1 (en) | 2009-07-31 | 2010-07-09 | Methods for diagnosing or predicting hepatitis c outcome in hcv infected patients |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013500713A JP2013500713A (ja) | 2013-01-10 |
| JP2013500713A5 true JP2013500713A5 (enExample) | 2013-08-15 |
Family
ID=42727569
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012522282A Pending JP2013500713A (ja) | 2009-07-31 | 2010-07-09 | Hcv感染患者においてc型肝炎の転帰を診断又は予測する方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20110165124A1 (enExample) |
| EP (1) | EP2459210A1 (enExample) |
| JP (1) | JP2013500713A (enExample) |
| KR (1) | KR20120040725A (enExample) |
| CN (1) | CN102665753A (enExample) |
| AU (1) | AU2010277239A1 (enExample) |
| BR (1) | BR112012001931A2 (enExample) |
| CA (1) | CA2768772A1 (enExample) |
| MX (1) | MX2012001058A (enExample) |
| WO (1) | WO2011013019A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5656159B2 (ja) * | 2009-08-24 | 2015-01-21 | 独立行政法人理化学研究所 | インターフェロン療法の効果予測用マーカー |
| RU2567806C2 (ru) * | 2009-12-22 | 2015-11-10 | ЯНССЕН Ар ЭНД Ди АЙРЛЭНД | Усиление прогностической ценности полиморфизма гена il28b в комбинации с количественной оценкой ip-10 в сыворотке при ответе на пегинторферон и рибавирин по сравнению с каждым из этих биомаркеров в отдельности |
| WO2012107584A1 (en) | 2011-02-11 | 2012-08-16 | Universite Pierre Et Marie Curie (Paris 6) | Methods for predicting outcome of a hepatitis virus infection |
| JP2014509628A (ja) * | 2011-03-31 | 2014-04-21 | ノバルティス アーゲー | C型肝炎ウイルス感染症を治療するためのアリスポリビル |
| US20140154209A1 (en) * | 2011-06-30 | 2014-06-05 | Centre Hospitalier Universitaire Vaudois | Polymorphisms associated with non-response to a hepatitis c treatment or susceptibility to non-spontaneous hepatitis c clearance |
| MX2014001355A (es) | 2011-08-03 | 2014-11-21 | Cytheris | Inmunoterapia contra el vhc. |
| JP2013074888A (ja) * | 2011-09-15 | 2013-04-25 | Arkray Inc | IL28B(rs8099917)とITPA(rs1127354)の変異を検出する方法 |
| US20140271542A1 (en) * | 2011-10-05 | 2014-09-18 | The United States Of America As Represented By The Secretary, Department Of Health And Human Service | Genetic marker for predicting prognosis in patients infected with hepatitis c virus |
| GB2515942A (en) | 2011-10-21 | 2015-01-07 | Abbvie Inc | Combination treatment (e.g. with ABT-072 or ABT-333) of DAAs for use in treating HCV |
| US8492386B2 (en) | 2011-10-21 | 2013-07-23 | Abbvie Inc. | Methods for treating HCV |
| PT107894A (pt) | 2011-10-21 | 2014-10-31 | Abbvie Inc | Métodos para o tratamento de hcv compreendendo pelo menos dois agentes antivirais de actuação directa, ribavirina, mas não interferão. |
| US8466159B2 (en) | 2011-10-21 | 2013-06-18 | Abbvie Inc. | Methods for treating HCV |
| AU2013240301B2 (en) | 2012-03-28 | 2017-10-05 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | A novel interferon-lambda4 (IFNL4) protein, related nucleic acid molecules, and uses thereof |
| CN102816838A (zh) * | 2012-07-06 | 2012-12-12 | 吉林艾迪康医学检验所有限公司 | 用于检测丙型肝炎患者il28b snp12980275多态性的试剂盒 |
| US11192914B2 (en) | 2016-04-28 | 2021-12-07 | Emory University | Alkyne containing nucleotide and nucleoside therapeutic compositions and uses related thereto |
| CN108220424A (zh) * | 2018-02-05 | 2018-06-29 | 广州和康医疗技术有限公司 | 一种检测il28基因位点的方法及试剂盒 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5001050A (en) | 1989-03-24 | 1991-03-19 | Consejo Superior Investigaciones Cientificas | PHφ29 DNA polymerase |
| US5846717A (en) | 1996-01-24 | 1998-12-08 | Third Wave Technologies, Inc. | Detection of nucleic acid sequences by invader-directed cleavage |
| US5888780A (en) | 1992-12-07 | 1999-03-30 | Third Wave Technologies, Inc. | Rapid detection and identification of nucleic acid variants |
| US5605798A (en) | 1993-01-07 | 1997-02-25 | Sequenom, Inc. | DNA diagnostic based on mass spectrometry |
| US6045996A (en) | 1993-10-26 | 2000-04-04 | Affymetrix, Inc. | Hybridization assays on oligonucleotide arrays |
| US6068818A (en) | 1993-11-01 | 2000-05-30 | Nanogen, Inc. | Multicomponent devices for molecular biological analysis and diagnostics |
| ZA959469B (en) | 1994-11-15 | 1996-05-15 | South African Druggists Ltd | Pharmaceutical composition |
| WO1997001603A1 (en) | 1995-06-26 | 1997-01-16 | Henkel Corporation | Methods of preparing inorganic pigment dispersions |
| US6001311A (en) | 1997-02-05 | 1999-12-14 | Protogene Laboratories, Inc. | Apparatus for diverse chemical synthesis using two-dimensional array |
| WO1999067641A2 (en) | 1998-06-24 | 1999-12-29 | Illumina, Inc. | Decoding of array sensors with microspheres |
| GB9817266D0 (en) | 1998-08-07 | 1998-10-07 | Imperial College | Method |
| US6429027B1 (en) | 1998-12-28 | 2002-08-06 | Illumina, Inc. | Composite arrays utilizing microspheres |
| JP2005204549A (ja) * | 2004-01-21 | 2005-08-04 | Hubit Genomix Inc | C型肝炎ウイルス感染者の経過に関する遺伝子およびその利用 |
| WO2006003654A2 (en) * | 2004-07-01 | 2006-01-12 | Medical Research Fund Of Tel Aviv Sourasky Medical Center | Methods and kits for predicting liver fibrosis progression rate in chronic hepatitis c patients |
| WO2010025380A2 (en) * | 2008-08-28 | 2010-03-04 | Vertex Pharmaceuticals Incorporated | Analysis of hcv genotypes |
| WO2010135649A1 (en) * | 2009-05-21 | 2010-11-25 | Schering Corporation | Genetic markers associated with interferon-alpha response |
-
2010
- 2010-07-09 BR BR112012001931A patent/BR112012001931A2/pt not_active IP Right Cessation
- 2010-07-09 JP JP2012522282A patent/JP2013500713A/ja active Pending
- 2010-07-09 CN CN2010800436612A patent/CN102665753A/zh active Pending
- 2010-07-09 CA CA2768772A patent/CA2768772A1/en not_active Abandoned
- 2010-07-09 KR KR1020127005379A patent/KR20120040725A/ko not_active Withdrawn
- 2010-07-09 WO PCT/IB2010/053139 patent/WO2011013019A1/en not_active Ceased
- 2010-07-09 AU AU2010277239A patent/AU2010277239A1/en not_active Abandoned
- 2010-07-09 MX MX2012001058A patent/MX2012001058A/es not_active Application Discontinuation
- 2010-07-09 EP EP10740746A patent/EP2459210A1/en not_active Withdrawn
- 2010-07-29 US US12/846,356 patent/US20110165124A1/en not_active Abandoned
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