JP2012509846A5 - - Google Patents

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Publication number
JP2012509846A5
JP2012509846A5 JP2011532298A JP2011532298A JP2012509846A5 JP 2012509846 A5 JP2012509846 A5 JP 2012509846A5 JP 2011532298 A JP2011532298 A JP 2011532298A JP 2011532298 A JP2011532298 A JP 2011532298A JP 2012509846 A5 JP2012509846 A5 JP 2012509846A5
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JP
Japan
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substituted
pharmaceutical composition
group
amino acid
alkyl
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JP2011532298A
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English (en)
Japanese (ja)
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JP2012509846A (ja
JP5706825B2 (ja
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Priority claimed from PCT/US2009/061068 external-priority patent/WO2010045599A1/en
Publication of JP2012509846A publication Critical patent/JP2012509846A/ja
Publication of JP2012509846A5 publication Critical patent/JP2012509846A5/ja
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Publication of JP5706825B2 publication Critical patent/JP5706825B2/ja
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JP2011532298A 2008-10-17 2009-10-16 フェノール性オピオイドの放出が減弱された医薬組成物 Active JP5706825B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10640008P 2008-10-17 2008-10-17
US61/106,400 2008-10-17
PCT/US2009/061068 WO2010045599A1 (en) 2008-10-17 2009-10-16 Pharmaceutical compositions with attenuated release of phenolic opioids

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015037724A Division JP2015129167A (ja) 2008-10-17 2015-02-27 フェノール性オピオイドの放出が減弱された医薬組成物

Publications (3)

Publication Number Publication Date
JP2012509846A JP2012509846A (ja) 2012-04-26
JP2012509846A5 true JP2012509846A5 (enExample) 2012-12-06
JP5706825B2 JP5706825B2 (ja) 2015-04-22

Family

ID=41466912

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2011532298A Active JP5706825B2 (ja) 2008-10-17 2009-10-16 フェノール性オピオイドの放出が減弱された医薬組成物
JP2015037724A Pending JP2015129167A (ja) 2008-10-17 2015-02-27 フェノール性オピオイドの放出が減弱された医薬組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2015037724A Pending JP2015129167A (ja) 2008-10-17 2015-02-27 フェノール性オピオイドの放出が減弱された医薬組成物

Country Status (12)

Country Link
US (2) US8802681B2 (enExample)
EP (1) EP2349241B1 (enExample)
JP (2) JP5706825B2 (enExample)
KR (1) KR20110081852A (enExample)
CN (1) CN102186467B (enExample)
AU (1) AU2009305563C1 (enExample)
CA (1) CA2739936C (enExample)
IL (1) IL212081A (enExample)
MX (1) MX2011004095A (enExample)
RU (1) RU2562583C2 (enExample)
WO (1) WO2010045599A1 (enExample)
ZA (1) ZA201102361B (enExample)

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US20110262355A1 (en) 2010-04-21 2011-10-27 Jenkins Thomas E Compositions comprising enzyme-cleavable opioid prodrugs and inhibitors thereof
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US20110262359A1 (en) * 2010-04-21 2011-10-27 Jenkins Thomas E Compositions comprising enzyme-cleavable prodrugs of active agents and inhibitors thereof
US8497237B2 (en) 2011-01-11 2013-07-30 Signature Therapeutics, Inc. Compositions comprising enzyme-cleavable oxycodone prodrug
AU2012205733B2 (en) * 2011-01-11 2015-10-08 Signature Therapeutics, Inc. Compositions comprising enzyme-cleavable oxycodone prodrug
JP6148182B2 (ja) * 2011-03-09 2017-06-14 シグネーチャー セラピューティクス, インク.Signature Therapeutics, Inc. 複素環式リンカーを有する活性薬剤プロドラッグ
WO2012122420A2 (en) 2011-03-09 2012-09-13 Pharmacofore, Inc. Opioid prodrugs with heterocyclic linkers
WO2016064914A1 (en) 2014-10-20 2016-04-28 Elysium Therapeutics, Inc. Diversion-resistant opioid formulations
US11634384B2 (en) 2014-11-25 2023-04-25 Concentric Analgesics, Inc. Prodrugs of phenolic TRPV1 agonists
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US10335406B2 (en) * 2015-10-01 2019-07-02 Elysium Therapeutics, Inc. Opioid compositions resistant to overdose and abuse
EP3463576A4 (en) 2016-05-25 2020-01-15 Concentric Analgesics, Inc. PRODRUGS BY PHENOLIC TRPV1 AGONISTS IN COMBINATION WITH LOCAL ANESTHETIC AND VASOCONSTRICTORS FOR IMPROVED LOCAL ANESTHESIA
EP3595663A4 (en) * 2017-03-17 2021-01-13 Elysium Therapeutics, Inc. MULTIPLE SUBUNITY OPIOID PRODRUGS WITH RESISTANCE TO OVERDOSE AND ABUSE
WO2020023794A1 (en) 2018-07-27 2020-01-30 Concentric Analgesics, Inc. Pegylated prodrugs of phenolic trpv1 agonists
WO2020181000A1 (en) 2019-03-06 2020-09-10 Ensysce Biosciences, Inc. Compositions comprising enzyme-cleavable amphetamine prodrugs and inhibitors thereof
IL305493A (en) * 2021-03-09 2023-10-01 Ensysce Biosciences Inc Compositions comprising enzyme-cleavable prodrugs and controlled release nafamostat and methods of use thereof
CA3230025A1 (en) 2021-09-29 2023-04-06 Lynn Kirkpatrick Enzyme-cleavable methadone prodrugs and methods of use thereof

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