JP2010502585A5 - - Google Patents
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- Publication number
- JP2010502585A5 JP2010502585A5 JP2009526190A JP2009526190A JP2010502585A5 JP 2010502585 A5 JP2010502585 A5 JP 2010502585A5 JP 2009526190 A JP2009526190 A JP 2009526190A JP 2009526190 A JP2009526190 A JP 2009526190A JP 2010502585 A5 JP2010502585 A5 JP 2010502585A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- amino acid
- acid residue
- compound according
- derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 150000001875 compounds Chemical class 0.000 claims 7
- 125000000539 amino acid group Chemical group 0.000 claims 3
- 239000004475 Arginine Substances 0.000 claims 2
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 claims 2
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims 2
- 235000003704 aspartic acid Nutrition 0.000 claims 2
- OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 claims 2
- 238000002059 diagnostic imaging Methods 0.000 claims 2
- 239000012216 imaging agent Substances 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- NMDDZEVVQDPECF-LURJTMIESA-N (2s)-2,7-diaminoheptanoic acid Chemical compound NCCCCC[C@H](N)C(O)=O NMDDZEVVQDPECF-LURJTMIESA-N 0.000 claims 1
- VILCJCGEZXAXTO-UHFFFAOYSA-N 2,2,2-tetramine Chemical compound NCCNCCNCCN VILCJCGEZXAXTO-UHFFFAOYSA-N 0.000 claims 1
- JHALWMSZGCVVEM-UHFFFAOYSA-N 2-[4,7-bis(carboxymethyl)-1,4,7-triazonan-1-yl]acetic acid Chemical compound OC(=O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CC1 JHALWMSZGCVVEM-UHFFFAOYSA-N 0.000 claims 1
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 claims 1
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 claims 1
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 claims 1
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 claims 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims 1
- 239000004472 Lysine Substances 0.000 claims 1
- NTWVQPHTOUKMDI-YFKPBYRVSA-N N-Methyl-arginine Chemical compound CN[C@H](C(O)=O)CCCN=C(N)N NTWVQPHTOUKMDI-YFKPBYRVSA-N 0.000 claims 1
- WDLRUFUQRNWCPK-UHFFFAOYSA-N Tetraxetan Chemical compound OC(=O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1 WDLRUFUQRNWCPK-UHFFFAOYSA-N 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- 235000001014 amino acid Nutrition 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 239000002738 chelating agent Substances 0.000 claims 1
- 238000002405 diagnostic procedure Methods 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 235000013922 glutamic acid Nutrition 0.000 claims 1
- 239000004220 glutamic acid Substances 0.000 claims 1
- 230000002209 hydrophobic effect Effects 0.000 claims 1
- 238000011503 in vivo imaging Methods 0.000 claims 1
- 235000018977 lysine Nutrition 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 125000006850 spacer group Chemical group 0.000 claims 1
- 150000003573 thiols Chemical class 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US82368206P | 2006-08-28 | 2006-08-28 | |
| PCT/IB2007/002479 WO2008026040A2 (en) | 2006-08-28 | 2007-08-28 | 68ga-labeled peptide-based radiopharmaceuticals |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010502585A JP2010502585A (ja) | 2010-01-28 |
| JP2010502585A5 true JP2010502585A5 (enExample) | 2011-09-15 |
Family
ID=38961954
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009526190A Pending JP2010502585A (ja) | 2006-08-28 | 2007-08-28 | ６８Ｇａ標識ペプチド系放射性医薬品 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20100233082A1 (enExample) |
| EP (1) | EP2056886A2 (enExample) |
| JP (1) | JP2010502585A (enExample) |
| CN (1) | CN101528270A (enExample) |
| WO (1) | WO2008026040A2 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2722858C (en) * | 2008-04-30 | 2017-08-29 | Siemens Medical Solutions Usa, Inc. | Substrate based pet imaging agents |
| GB0814722D0 (en) * | 2008-08-12 | 2008-09-17 | Ge Healthcare Ltd | Treatment monitoring |
| JP5690733B2 (ja) * | 2009-08-20 | 2015-03-25 | 富士フイルムＲｉファーマ株式会社 | ビスホスホン酸誘導体及びその放射性金属核種標識体 |
| ITFI20110180A1 (it) * | 2011-08-12 | 2013-02-13 | Advanced Accelerator Applic S A | Processo per la preparazione di complessi di 68ga. |
| CA2903261C (en) * | 2012-12-03 | 2021-03-09 | Curasight Aps | Positron emitting radionuclide labeled peptides for human upar pet imaging |
| GB201511036D0 (en) * | 2015-06-23 | 2015-08-05 | Guy S And St Thomas Hospital Nhs Foundation Trust | Imaging method |
| JP2020506921A (ja) * | 2017-01-30 | 2020-03-05 | ヴェクト−オールＶｅｃｔ−Ｈｏｒｕｓ | がんイメージング及びがん放射線治療のための組成物及び方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1230441C (zh) * | 2000-04-12 | 2005-12-07 | 安盛药业有限公司 | 结合整联蛋白的肽衍生物 |
| NO20004795D0 (no) * | 2000-09-26 | 2000-09-26 | Nycomed Imaging As | Peptidbaserte forbindelser |
| IL159310A0 (en) * | 2001-07-10 | 2004-06-01 | Amersham Health As | Peptide-based compounds |
| GB0308408D0 (en) * | 2003-04-11 | 2003-05-21 | Amersham Plc | Microwave activation |
| US8182790B2 (en) * | 2004-11-22 | 2012-05-22 | Ge Healthcare As | Contrast agents |
| GB0428012D0 (en) * | 2004-12-22 | 2005-01-26 | Hammersmith Imanet Ltd | Radiolabelling methods |
-
2007
- 2007-08-28 CN CNA2007800402050A patent/CN101528270A/zh active Pending
- 2007-08-28 EP EP07804849A patent/EP2056886A2/en not_active Withdrawn
- 2007-08-28 US US12/376,800 patent/US20100233082A1/en not_active Abandoned
- 2007-08-28 WO PCT/IB2007/002479 patent/WO2008026040A2/en not_active Ceased
- 2007-08-28 JP JP2009526190A patent/JP2010502585A/ja active Pending
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