JP2012025784A5 - - Google Patents
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- JP2012025784A5 JP2012025784A5 JP2011244904A JP2011244904A JP2012025784A5 JP 2012025784 A5 JP2012025784 A5 JP 2012025784A5 JP 2011244904 A JP2011244904 A JP 2011244904A JP 2011244904 A JP2011244904 A JP 2011244904A JP 2012025784 A5 JP2012025784 A5 JP 2012025784A5
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- Japan
- Prior art keywords
- virus
- culture
- vaccine
- respect
- circovirus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 238000000034 method Methods 0.000 claims 13
- 241000700605 Viruses Species 0.000 claims 8
- 238000012360 testing method Methods 0.000 claims 4
- 229960005486 vaccine Drugs 0.000 claims 4
- 238000001514 detection method Methods 0.000 claims 3
- 244000052769 pathogen Species 0.000 claims 3
- 241000271566 Aves Species 0.000 claims 2
- 241001533384 Circovirus Species 0.000 claims 2
- 239000000427 antigen Substances 0.000 claims 2
- 102000036639 antigens Human genes 0.000 claims 2
- 108091007433 antigens Proteins 0.000 claims 2
- 230000001717 pathogenic effect Effects 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- 241000701242 Adenoviridae Species 0.000 claims 1
- 241000701931 Canine parvovirus Species 0.000 claims 1
- 238000002965 ELISA Methods 0.000 claims 1
- 241000700586 Herpesviridae Species 0.000 claims 1
- 102000018697 Membrane Proteins Human genes 0.000 claims 1
- 108010052285 Membrane Proteins Proteins 0.000 claims 1
- 241000204031 Mycoplasma Species 0.000 claims 1
- 208000002606 Paramyxoviridae Infections Diseases 0.000 claims 1
- 241000202347 Porcine circovirus Species 0.000 claims 1
- 241000702619 Porcine parvovirus Species 0.000 claims 1
- 241000125945 Protoparvovirus Species 0.000 claims 1
- 241000702247 Reoviridae Species 0.000 claims 1
- 208000036142 Viral infection Diseases 0.000 claims 1
- 108700010877 adenoviridae proteins Proteins 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- 239000001963 growth medium Substances 0.000 claims 1
- 230000000984 immunochemical effect Effects 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 238000004806 packaging method and process Methods 0.000 claims 1
- 238000000751 protein extraction Methods 0.000 claims 1
- 238000003908 quality control method Methods 0.000 claims 1
- 238000011084 recovery Methods 0.000 claims 1
- 238000003757 reverse transcription PCR Methods 0.000 claims 1
- 239000000758 substrate Substances 0.000 claims 1
- 210000003501 vero cell Anatomy 0.000 claims 1
- 230000009385 viral infection Effects 0.000 claims 1
Claims (9)
- Ｖｅｒｏ細胞株の培養物中でワクチン抗原を調製するための方法であって、
パルボウイルス、および、サーコウイルスからなる群より選択される病原体に関して試験する工程、
を包含する、方法。 - 前記病原体がイヌパルボウイルス、ブタパルボウイルス、または、ブタサーコウイルスである、請求項１に記載の方法。
- 種ウイルスおよび／または細胞基質および／または培養培地が試験される、請求項１または２に記載の方法。
- 前記方法が、ウイルス培養物を創出するのに使用する物質に関して、ウイルス培養物自体に関して、または、ウイルス培養物から抽出した物質およびこれに派生する物質に関して、実行される、請求項１〜３のいずれか一項に記載の方法。
- 種ウイルスおよび／またはワクチン抗原および／または培養物を、パラインフルエンザウイルス、ヘルペスウイルス科、アデノウイルス科、マイコプラズマ属、トリサーコウイルス、およびトリレオウイルス科からなる群より選択される病原体の存在に関して試験する工程；
を包含する、請求項１〜４のうちのいずれか１項に記載の方法。 - 前記培養物を、免疫化学的検出および／または核酸検出によって試験する、請求項１〜５のうちのいずれか１項に記載の方法。
- 前記検出が、ＥＬＩＳＡおよび／またはＰＣＲ（ＲＴ−ＰＣＲを含む）によるものである、請求項６に記載の方法。
- 試験が、以下：
ウイルス感染、増殖段階、ウイルス回収、ウイルス処理、スプリット、表面タンパク質の抽出、ワクチン処方、ワクチンパッケージングの１つの段階で行われる、請求項１〜７のうちのいずれか１項に記載の方法。 - 試験が、通常の品質管理の一部として行われる、請求項１〜８のうちのいずれか１項に記載の方法。
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04255471 | 2004-09-09 | ||
| EP04255471.7 | 2004-09-09 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011158471A Division JP2011207911A (ja) | 2004-09-09 | 2011-07-19 | インフルエンザワクチンに関連する潜在的医原性リスクの減少 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013030624A Division JP2013100358A (ja) | 2004-09-09 | 2013-02-20 | インフルエンザワクチンに関連する潜在的医原性リスクの減少 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012025784A JP2012025784A (ja) | 2012-02-09 |
| JP2012025784A5 true JP2012025784A5 (ja) | 2013-03-21 |
Family
ID=35520177
Family Applications (7)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007530801A Withdrawn JP2008512443A (ja) | 2004-09-09 | 2005-09-09 | インフルエンザワクチンに関連する潜在的医原性リスクの減少 |
| JP2011158471A Withdrawn JP2011207911A (ja) | 2004-09-09 | 2011-07-19 | インフルエンザワクチンに関連する潜在的医原性リスクの減少 |
| JP2011244904A Withdrawn JP2012025784A (ja) | 2004-09-09 | 2011-11-08 | インフルエンザワクチンに関連する潜在的医原性リスクの減少 |
| JP2013030624A Withdrawn JP2013100358A (ja) | 2004-09-09 | 2013-02-20 | インフルエンザワクチンに関連する潜在的医原性リスクの減少 |
| JP2015155818A Pending JP2015205929A (ja) | 2004-09-09 | 2015-08-06 | インフルエンザワクチンに関連する潜在的医原性リスクの減少 |
| JP2016230896A Withdrawn JP2017057209A (ja) | 2004-09-09 | 2016-11-29 | インフルエンザワクチンに関連する潜在的医原性リスクの減少 |
| JP2019146040A Pending JP2019210292A (ja) | 2004-09-09 | 2019-08-08 | インフルエンザワクチンに関連する潜在的医原性リスクの減少 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007530801A Withdrawn JP2008512443A (ja) | 2004-09-09 | 2005-09-09 | インフルエンザワクチンに関連する潜在的医原性リスクの減少 |
| JP2011158471A Withdrawn JP2011207911A (ja) | 2004-09-09 | 2011-07-19 | インフルエンザワクチンに関連する潜在的医原性リスクの減少 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013030624A Withdrawn JP2013100358A (ja) | 2004-09-09 | 2013-02-20 | インフルエンザワクチンに関連する潜在的医原性リスクの減少 |
| JP2015155818A Pending JP2015205929A (ja) | 2004-09-09 | 2015-08-06 | インフルエンザワクチンに関連する潜在的医原性リスクの減少 |
| JP2016230896A Withdrawn JP2017057209A (ja) | 2004-09-09 | 2016-11-29 | インフルエンザワクチンに関連する潜在的医原性リスクの減少 |
| JP2019146040A Pending JP2019210292A (ja) | 2004-09-09 | 2019-08-08 | インフルエンザワクチンに関連する潜在的医原性リスクの減少 |
Country Status (16)
| Country | Link |
|---|---|
| US (6) | US8119337B2 (ja) |
| EP (5) | EP2179744B1 (ja) |
| JP (7) | JP2008512443A (ja) |
| AT (2) | ATE488248T1 (ja) |
| CA (2) | CA2890962A1 (ja) |
| CY (3) | CY1111180T1 (ja) |
| DE (3) | DE602005025170D1 (ja) |
| DK (4) | DK2578229T3 (ja) |
| ES (4) | ES2386272T3 (ja) |
| HK (2) | HK1105364A1 (ja) |
| HR (4) | HRP20100673T1 (ja) |
| PL (4) | PL2236155T3 (ja) |
| PT (4) | PT2179744E (ja) |
| RS (3) | RS51721B (ja) |
| SI (4) | SI2578229T1 (ja) |
| WO (1) | WO2006027698A1 (ja) |
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| WO2007052056A1 (en) | 2005-11-04 | 2007-05-10 | Novartis Vaccines And Diagnostics Srl | Adjuvanted influenza vaccines including cytokine-inducing agents |
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| DE10144906B4 (de) | 2001-09-12 | 2013-11-28 | Novartis Vaccines And Diagnostics Gmbh | Verfahren zur großtechnischen Herstellung von Impfstoffen |
| DE10144903A1 (de) * | 2001-09-12 | 2003-03-27 | Chiron Behring Gmbh & Co | Vermehrung von Viren in Zellkultur |
| FR2836924B1 (fr) | 2002-03-08 | 2005-01-14 | Vivalis | Lignees de cellules aviaires utiles pour la production de substances d'interet |
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