JP2011500598A5 - - Google Patents

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Publication number
JP2011500598A5
JP2011500598A5 JP2010529091A JP2010529091A JP2011500598A5 JP 2011500598 A5 JP2011500598 A5 JP 2011500598A5 JP 2010529091 A JP2010529091 A JP 2010529091A JP 2010529091 A JP2010529091 A JP 2010529091A JP 2011500598 A5 JP2011500598 A5 JP 2011500598A5
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JP
Japan
Prior art keywords
pain
ring
aliphatic
cor
membered
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JP2010529091A
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English (en)
Japanese (ja)
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JP5555169B2 (ja
JP2011500598A (ja
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Priority claimed from PCT/US2008/079542 external-priority patent/WO2009049180A2/en
Publication of JP2011500598A publication Critical patent/JP2011500598A/ja
Publication of JP2011500598A5 publication Critical patent/JP2011500598A5/ja
Application granted granted Critical
Publication of JP5555169B2 publication Critical patent/JP5555169B2/ja
Expired - Fee Related legal-status Critical Current
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JP2010529091A 2007-10-11 2008-10-10 電位開口型ナトリウムチャネルの阻害剤として有用なヘテロアリールアミド Expired - Fee Related JP5555169B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US97925807P 2007-10-11 2007-10-11
US60/979,258 2007-10-11
PCT/US2008/079542 WO2009049180A2 (en) 2007-10-11 2008-10-10 Heteroaryl amides useful as inhibitors of voltage-gated sodium channels

Publications (3)

Publication Number Publication Date
JP2011500598A JP2011500598A (ja) 2011-01-06
JP2011500598A5 true JP2011500598A5 (enExample) 2012-11-15
JP5555169B2 JP5555169B2 (ja) 2014-07-23

Family

ID=40429979

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010529091A Expired - Fee Related JP5555169B2 (ja) 2007-10-11 2008-10-10 電位開口型ナトリウムチャネルの阻害剤として有用なヘテロアリールアミド

Country Status (9)

Country Link
US (1) US8519137B2 (enExample)
EP (1) EP2227453B1 (enExample)
JP (1) JP5555169B2 (enExample)
CN (1) CN101883760A (enExample)
AU (1) AU2008310660A1 (enExample)
CA (1) CA2701946A1 (enExample)
MX (1) MX2010003866A (enExample)
NZ (1) NZ584475A (enExample)
WO (1) WO2009049180A2 (enExample)

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GEAP202315648A (en) 2018-11-02 2023-07-25 Merck Sharp & Dohme Llc 2-amino-n-heteroaryl-nicotinamides as nav1.8 inhibitors
WO2020092187A1 (en) * 2018-11-02 2020-05-07 Merck Sharp & Dohme Corp. 2-amino-n-phenyl-nicotinamides as nav1.8 inhibitors
WO2020146682A1 (en) 2019-01-10 2020-07-16 Vertex Pharmaceuticals Incorporated Carboxamides as modulators of sodium channels
WO2020146612A1 (en) 2019-01-10 2020-07-16 Vertex Pharmaceuticals Incorporated Esters and carbamates as modulators of sodium channels
WO2020199683A1 (zh) * 2019-04-04 2020-10-08 上海海雁医药科技有限公司 氮杂环取代的磺酰基苯甲酰胺衍生物、其制法与医药上的用途
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US11802122B2 (en) 2020-06-17 2023-10-31 Merck Sharp & Dohme Llc 2-oxoimidazolidine-4-carboxamides as NAv1.8 inhibitors
KR20230026404A (ko) 2020-06-17 2023-02-24 머크 샤프 앤드 돔 엘엘씨 Nav1.8 억제제로서의 2-옥소-옥사졸리딘-5-카르복스아미드
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