|
US49728A
(en)
*
|
|
1865-09-05 |
|
Improvement |
|
US82365A
(en)
*
|
|
1868-09-22 |
|
thompson |
|
US220227A
(en)
*
|
|
1879-10-07 |
|
Improvement in stri klng-movements for clocks |
|
US95650A
(en)
*
|
|
1869-10-12 |
|
Improvement in machines for bending sheet-metal for cornices |
|
DE239090C
(cg-RX-API-DMAC7.html)
|
1906-11-01 |
|
|
|
|
US2749344A
(en)
|
1953-01-02 |
1956-06-05 |
Burroughs Wellcome Co |
Pyrimidine compounds
|
|
DE1224316B
(de)
|
1961-03-18 |
1966-09-08 |
Beiersdorf & Co Ag P |
Verfahren zur Herstellung von 2-Methyl-3-(o-aethylphenyl)-4-oxo-3, 4-dihydrochinazolin und dessen Salzen
|
|
US3515787A
(en)
*
|
1962-06-27 |
1970-06-02 |
Squibb & Sons Inc |
Compositions and methods for producing a muscle relaxing effect in an animal with 2,3 - substituted - 6 - amino-4-quinazolones
|
|
DE1232152B
(de)
|
1962-06-27 |
1967-01-12 |
Heyden Chem Fab |
Verfahren zur Herstellung von 3-Phenylchinazolinon-(4)-derivaten
|
|
GB1003802A
(en)
|
1963-06-04 |
1965-09-08 |
Searle & Co |
Pyrimidinone derivatives
|
|
DE1280874B
(de)
*
|
1963-10-09 |
1968-10-24 |
Boehringer Sohn Ingelheim |
2-Methyl-3-(2-dimethylaminophenyl)-8-amino-3H-chinazolon-(4)
|
|
US3317388A
(en)
|
1964-11-20 |
1967-05-02 |
Wallace & Tiernan Inc |
Methods for treating pain
|
|
US3864362A
(en)
|
1970-05-27 |
1975-02-04 |
Chinoin Gyogyszer Es Vegyeszet |
Iso flavones
|
|
BE793594A
(fr)
|
1972-01-03 |
1973-07-02 |
Pfizer |
Nouvelles 6,7-dimethoxyquinazolines utiles comme analgesiques et tranquillisants
|
|
GB1495305A
(en)
|
1975-09-12 |
1977-12-14 |
Pfizer Ltd |
3-phenyl-4-oxo-4h-benzopyran derivatives
|
|
US4501755A
(en)
|
1981-05-01 |
1985-02-26 |
Pennwalt Corporation |
Isoflavones useful as anti-inflammatory agents
|
|
JPS59128376A
(ja)
*
|
1983-01-13 |
1984-07-24 |
Tanabe Seiyaku Co Ltd |
キナゾリノン誘導体
|
|
SU1262927A1
(ru)
|
1985-01-09 |
1997-11-20 |
Институт физико-органической химии и углехимии АН УССР |
Способ получения 6-бром-5-метилимидазо(4,5-в)пиридина
|
|
JPS62201882A
(ja)
|
1985-11-18 |
1987-09-05 |
Yamanouchi Pharmaceut Co Ltd |
イソフラボン誘導体
|
|
JPS62193605A
(ja)
|
1986-02-20 |
1987-08-25 |
Toray Ind Inc |
半透性複合膜の製造方法
|
|
ZA873745B
(en)
|
1986-06-04 |
1988-10-26 |
Daiichi Seiyaku Co |
Benzopyran derivatives
|
|
US5290780A
(en)
*
|
1991-01-30 |
1994-03-01 |
American Cyanamid Co. |
Angiotensin II receptor blocking 2,3,6 substituted quinazolinones
|
|
WO1992013535A1
(en)
*
|
1991-02-06 |
1992-08-20 |
Research Corporation Technologies, Inc. |
Anticonvulsant substituted quinazolones
|
|
US5958930A
(en)
|
1991-04-08 |
1999-09-28 |
Duquesne University Of The Holy Ghost |
Pyrrolo pyrimidine and furo pyrimidine derivatives
|
|
US5294617A
(en)
|
1993-04-23 |
1994-03-15 |
American Cyanamid Company |
Angiotensin II receptor blocking 2,3,6 substituted quinazolinones
|
|
US5284853A
(en)
|
1993-04-23 |
1994-02-08 |
American Cyanamid Company |
Angiotensin II receptor blocking 2,3,6 substituted quinazolinones
|
|
EP0635263A3
(en)
|
1993-06-28 |
1995-09-27 |
American Cyanamid Co |
Angiotensin II antagonists (AII) as inhibitors of the growth of adipose tissue.
|
|
HUT68558A
(en)
|
1993-07-20 |
1995-06-28 |
Chinoin Gyogyszer Es Vegyeszet |
Method for preparing isoflavon derivatives
|
|
IL112235A
(en)
|
1994-01-03 |
2000-06-29 |
Acea Pharm Inc |
1,4-dihydro-pyrido¬2,3-b¾pyrazine-2,3-dione (5 or 8) oxide derivatives and pharmaceutical compositions containing them
|
|
JPH07258224A
(ja)
|
1994-03-24 |
1995-10-09 |
Dai Ichi Seiyaku Co Ltd |
二環性化合物
|
|
US5756502A
(en)
*
|
1994-08-08 |
1998-05-26 |
Warner-Lambert Company |
Quinazolinone derivatives as cholyecystokinin (CCK) ligands
|
|
HUP9801828A3
(en)
*
|
1995-03-14 |
2001-02-28 |
Novartis Ag |
Benzoic acid, quinoline and quinazoline derivatives, pharmaceutical compositions containing them and process for producing them
|
|
US5783577A
(en)
|
1995-09-15 |
1998-07-21 |
Trega Biosciences, Inc. |
Synthesis of quinazolinone libraries and derivatives thereof
|
|
WO1997028118A1
(en)
|
1996-02-05 |
1997-08-07 |
Hoechst Celanese Corporation |
Process for preparing anthranilic acids
|
|
WO1997044041A1
(en)
|
1996-05-20 |
1997-11-27 |
Merck & Co., Inc. |
Antagonists of gonadotropin releasing hormone
|
|
FR2750862B1
(fr)
|
1996-07-12 |
1998-10-16 |
Dupin Jean Pierre |
Utilisation d'heterocycles diazotes fusionnes avec un systeme aromatique ou heteroaromatique pour le traitement des maladies thrombo-emboliques
|
|
AU6908398A
(en)
|
1996-10-28 |
1998-05-22 |
Versicor Inc |
Fused 2,4-pyrimidinedione combinatorial libraries and biologically active fused 2,4-pyramidinediones
|
|
IT1289154B1
(it)
|
1997-01-03 |
1998-09-29 |
Chiesi Farma Spa |
Derivati di isoflavone loro preparazione e loro impiego terapeutico
|
|
JPH10259176A
(ja)
*
|
1997-03-17 |
1998-09-29 |
Japan Tobacco Inc |
血管新生阻害作用を有する新規アミド誘導体及びその用途
|
|
US5948775A
(en)
|
1997-03-19 |
1999-09-07 |
American Home Products Corporation |
2- or 3-(substitutedaminoalkoxyphenyl)quinazolin-4-ones
|
|
JP4444493B2
(ja)
|
1997-08-20 |
2010-03-31 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
カプサイシン受容体およびカプサイシン受容体関連ポリペプチドをコードする核酸配列ならびにその使用
|
|
DE69910538T2
(de)
|
1998-01-22 |
2004-06-24 |
The Regents Of The University Of California, Oakland |
Nukleinsäuresequenzen, welche für capsaicin-rezeptoren kodieren
|
|
GEP20032920B
(en)
|
1998-02-25 |
2003-03-25 |
Genetics Inst |
Inhibitors of Phospholipase Enzymes
|
|
US6500853B1
(en)
|
1998-02-28 |
2002-12-31 |
Genetics Institute, Llc |
Inhibitors of phospholipase enzymes
|
|
EP1154989B1
(en)
*
|
1999-02-22 |
2005-12-14 |
Pacific Corporation |
Vanilloid analogues containing resiniferatoxin pharmacophores as potent vanilloid receptor agonists and analgesics, compositions and uses thereof
|
|
GB9920912D0
(en)
|
1999-09-03 |
1999-11-10 |
Indena Spa |
Novel derivatives of flavones,xanthones and coumarins
|
|
AU4742101A
(en)
|
2000-03-17 |
2001-10-03 |
Merck & Co., Inc. |
Antagonists of gonadotropin releasing hormone
|
|
IL153884A0
(en)
|
2000-07-20 |
2003-07-31 |
Neurogen Corp |
Capsaicin receptor ligands
|
|
NZ523882A
(en)
*
|
2000-08-21 |
2004-11-26 |
Pacific Corp |
Novel thiourea derivatives and the pharmaceutical compositions containing the same
|
|
FR2815033B1
(fr)
|
2000-10-06 |
2003-09-05 |
Negma Lab |
Derives de 7-carboxy-flavones, porcede pour leur preparation et leur application en therapeutique
|
|
NZ526622A
(en)
|
2000-12-11 |
2006-07-28 |
Amgen Sf Llc |
CXCR3 antagonists
|
|
CZ20032561A3
(cs)
|
2001-03-26 |
2003-12-17 |
Novartis Ag |
Deriváty pyridinu, způsob jejich přípravy a farmaceutický prostředek, který je obsahuje
|
|
JP2005501873A
(ja)
|
2001-07-31 |
2005-01-20 |
バイエル・ヘルスケア・アクチェンゲゼルシャフト |
アミン誘導体
|
|
GB0128499D0
(en)
|
2001-11-28 |
2002-01-23 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
IL147416A
(en)
*
|
2001-12-31 |
2008-11-26 |
Israel State |
Combined modalities for improved cancer treatment
|
|
US7074805B2
(en)
*
|
2002-02-20 |
2006-07-11 |
Abbott Laboratories |
Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor
|
|
US7381730B2
(en)
|
2002-03-15 |
2008-06-03 |
Bristol-Myers Squibb Company |
3-arylquinazoline derivatives as selective estrogen receptor beta modulators
|
|
WO2003106435A1
(en)
†
|
2002-06-18 |
2003-12-24 |
Sankyo Company, Limited |
Fused-ring pyrimidin-4(3h)-one derivatives, processes for the preparation and uses thereof
|
|
CA2489251A1
(en)
|
2002-07-05 |
2004-01-15 |
F. Hoffmann-La Roche Ag |
Quinazoline derivatives
|
|
EP1398032A1
(en)
|
2002-09-10 |
2004-03-17 |
PheneX Pharmaceuticals AG |
4-Oxo-quinazolines as LXR nuclear receptor binding compounds
|
|
GB0223730D0
(en)
|
2002-10-11 |
2002-11-20 |
Novartis Ag |
Organic compounds
|
|
WO2004041755A2
(en)
|
2002-11-04 |
2004-05-21 |
Nps Pharmaceuticals, Inc. |
Quinazolinone compounds as calcilytics
|
|
KR101166749B1
(ko)
|
2003-02-11 |
2012-07-27 |
베르날리스(캠브리지)리미티드 |
열쇼크 단백질 저해제로서의 이소옥사졸 화합물
|
|
WO2004078719A1
(ja)
|
2003-03-06 |
2004-09-16 |
Ono Pharmaceutical Co., Ltd. |
インドール誘導体化合物およびその化合物を有効成分とする薬剤
|
|
JP2006193426A
(ja)
|
2003-09-05 |
2006-07-27 |
Sankyo Co Ltd |
置換された縮環ピリミジン−4(3h)−オン化合物
|
|
WO2005040112A1
(en)
|
2003-10-14 |
2005-05-06 |
Oxagen Limited |
Compounds with pgd2 antagonist activity
|
|
EP1687306A1
(en)
|
2003-11-14 |
2006-08-09 |
MERCK SHARP & DOHME LTD. |
Bicyclic pyrimidin-4-(3h)-ones and analogues and derivatives thereof which modulate the function of the vanilloid-1 receptor (vr1)
|
|
BRPI0507629A
(pt)
|
2004-02-13 |
2007-07-03 |
Banyu Pharma Co Ltd |
composto, antagonista do receptor e agonista inverso do receptor da histamina h3, agente profilático ou terapêutico para uma doença metabólica, uma doença circulatória ou uma doença do sistema nervoso, ou um seu sal farmaceuticamente aceitável
|
|
GB0412768D0
(en)
|
2004-06-08 |
2004-07-07 |
Novartis Ag |
Organic compounds
|
|
GB0412769D0
(en)
|
2004-06-08 |
2004-07-07 |
Novartis Ag |
Organic compounds
|
|
AU2006244027A1
(en)
|
2005-05-11 |
2006-11-16 |
Merck Sharp & Dohme Limited |
2,3-substituted fused bicyclic pyrimidin-4(3H)-ones modulating the function of the vanilloid-1 receptor (VR1)
|
|
GB0525068D0
(en)
|
2005-12-08 |
2006-01-18 |
Novartis Ag |
Organic compounds
|
|
ES2648225T3
(es)
|
2007-07-18 |
2017-12-29 |
Novartis Ag |
Combinaciones sinérgicas de antagonistas de VR-1 e inhibidores de COX-2
|
|
US8349852B2
(en)
|
2009-01-13 |
2013-01-08 |
Novartis Ag |
Quinazolinone derivatives useful as vanilloid antagonists
|