|
US95650A
(en)
*
|
|
1869-10-12 |
|
Improvement in machines for bending sheet-metal for cornices |
|
US220227A
(en)
*
|
|
1879-10-07 |
|
Improvement in stri klng-movements for clocks |
|
US49728A
(en)
*
|
|
1865-09-05 |
|
Improvement |
|
US82365A
(en)
*
|
|
1868-09-22 |
|
thompson |
|
DE239090C
(cg-RX-API-DMAC10.html)
|
1906-11-01 |
|
|
|
|
US2749344A
(en)
|
1953-01-02 |
1956-06-05 |
Burroughs Wellcome Co |
Pyrimidine compounds
|
|
DE1224316B
(de)
|
1961-03-18 |
1966-09-08 |
Beiersdorf & Co Ag P |
Verfahren zur Herstellung von 2-Methyl-3-(o-aethylphenyl)-4-oxo-3, 4-dihydrochinazolin und dessen Salzen
|
|
DE1232152B
(de)
*
|
1962-06-27 |
1967-01-12 |
Heyden Chem Fab |
Verfahren zur Herstellung von 3-Phenylchinazolinon-(4)-derivaten
|
|
US3515787A
(en)
*
|
1962-06-27 |
1970-06-02 |
Squibb & Sons Inc |
Compositions and methods for producing a muscle relaxing effect in an animal with 2,3 - substituted - 6 - amino-4-quinazolones
|
|
GB1003802A
(en)
*
|
1963-06-04 |
1965-09-08 |
Searle & Co |
Pyrimidinone derivatives
|
|
DE1280874B
(de)
*
|
1963-10-09 |
1968-10-24 |
Boehringer Sohn Ingelheim |
2-Methyl-3-(2-dimethylaminophenyl)-8-amino-3H-chinazolon-(4)
|
|
US3317388A
(en)
|
1964-11-20 |
1967-05-02 |
Wallace & Tiernan Inc |
Methods for treating pain
|
|
US3864362A
(en)
|
1970-05-27 |
1975-02-04 |
Chinoin Gyogyszer Es Vegyeszet |
Iso flavones
|
|
BE793594A
(fr)
|
1972-01-03 |
1973-07-02 |
Pfizer |
Nouvelles 6,7-dimethoxyquinazolines utiles comme analgesiques et tranquillisants
|
|
GB1495305A
(en)
|
1975-09-12 |
1977-12-14 |
Pfizer Ltd |
3-phenyl-4-oxo-4h-benzopyran derivatives
|
|
US4501755A
(en)
|
1981-05-01 |
1985-02-26 |
Pennwalt Corporation |
Isoflavones useful as anti-inflammatory agents
|
|
JPS59128376A
(ja)
*
|
1983-01-13 |
1984-07-24 |
Tanabe Seiyaku Co Ltd |
キナゾリノン誘導体
|
|
SU1262927A1
(ru)
|
1985-01-09 |
1997-11-20 |
Институт физико-органической химии и углехимии АН УССР |
Способ получения 6-бром-5-метилимидазо(4,5-в)пиридина
|
|
JPS62201882A
(ja)
|
1985-11-18 |
1987-09-05 |
Yamanouchi Pharmaceut Co Ltd |
イソフラボン誘導体
|
|
JPS62193605A
(ja)
*
|
1986-02-20 |
1987-08-25 |
Toray Ind Inc |
半透性複合膜の製造方法
|
|
ZA873745B
(en)
|
1986-06-04 |
1988-10-26 |
Daiichi Seiyaku Co |
Benzopyran derivatives
|
|
US5290780A
(en)
*
|
1991-01-30 |
1994-03-01 |
American Cyanamid Co. |
Angiotensin II receptor blocking 2,3,6 substituted quinazolinones
|
|
WO1992013535A1
(en)
*
|
1991-02-06 |
1992-08-20 |
Research Corporation Technologies, Inc. |
Anticonvulsant substituted quinazolones
|
|
US5958930A
(en)
|
1991-04-08 |
1999-09-28 |
Duquesne University Of The Holy Ghost |
Pyrrolo pyrimidine and furo pyrimidine derivatives
|
|
US5284853A
(en)
|
1993-04-23 |
1994-02-08 |
American Cyanamid Company |
Angiotensin II receptor blocking 2,3,6 substituted quinazolinones
|
|
US5294617A
(en)
|
1993-04-23 |
1994-03-15 |
American Cyanamid Company |
Angiotensin II receptor blocking 2,3,6 substituted quinazolinones
|
|
EP0635263A3
(en)
|
1993-06-28 |
1995-09-27 |
American Cyanamid Co |
Angiotensin II antagonists (AII) as inhibitors of the growth of adipose tissue.
|
|
HUT68558A
(en)
|
1993-07-20 |
1995-06-28 |
Chinoin Gyogyszer Es Vegyeszet |
Method for preparing isoflavon derivatives
|
|
IL112235A
(en)
|
1994-01-03 |
2000-06-29 |
Acea Pharm Inc |
1,4-dihydro-pyrido¬2,3-b¾pyrazine-2,3-dione (5 or 8) oxide derivatives and pharmaceutical compositions containing them
|
|
JPH07258224A
(ja)
|
1994-03-24 |
1995-10-09 |
Dai Ichi Seiyaku Co Ltd |
二環性化合物
|
|
US5756502A
(en)
*
|
1994-08-08 |
1998-05-26 |
Warner-Lambert Company |
Quinazolinone derivatives as cholyecystokinin (CCK) ligands
|
|
CA2214131C
(en)
*
|
1995-03-14 |
2009-06-23 |
Novartis Ag |
Trisubstituted phenyl derivatives
|
|
US5783577A
(en)
|
1995-09-15 |
1998-07-21 |
Trega Biosciences, Inc. |
Synthesis of quinazolinone libraries and derivatives thereof
|
|
WO1997028118A1
(en)
|
1996-02-05 |
1997-08-07 |
Hoechst Celanese Corporation |
Process for preparing anthranilic acids
|
|
EP0920319A4
(en)
|
1996-05-20 |
2002-05-02 |
Merck & Co Inc |
GONADOLIBERIN ANTAGONISTS
|
|
FR2750862B1
(fr)
|
1996-07-12 |
1998-10-16 |
Dupin Jean Pierre |
Utilisation d'heterocycles diazotes fusionnes avec un systeme aromatique ou heteroaromatique pour le traitement des maladies thrombo-emboliques
|
|
AU6908398A
(en)
|
1996-10-28 |
1998-05-22 |
Versicor Inc |
Fused 2,4-pyrimidinedione combinatorial libraries and biologically active fused 2,4-pyramidinediones
|
|
IT1289154B1
(it)
|
1997-01-03 |
1998-09-29 |
Chiesi Farma Spa |
Derivati di isoflavone loro preparazione e loro impiego terapeutico
|
|
JPH10259176A
(ja)
|
1997-03-17 |
1998-09-29 |
Japan Tobacco Inc |
血管新生阻害作用を有する新規アミド誘導体及びその用途
|
|
US5948775A
(en)
|
1997-03-19 |
1999-09-07 |
American Home Products Corporation |
2- or 3-(substitutedaminoalkoxyphenyl)quinazolin-4-ones
|
|
DE69819345T2
(de)
|
1997-08-20 |
2004-07-15 |
The Regents Of The University Of California, Oakland |
Für den capsaicin rezeptor kodierende nukleinsäuresequenzen und dem capsaicin rezeptor ähnliche polypeptide und ihre verwendung
|
|
AU2466799A
(en)
|
1998-01-22 |
1999-08-09 |
Regents Of The University Of California, The |
Nucleic acid sequences encoding capsaicin receptors
|
|
CN1310706A
(zh)
|
1998-02-25 |
2001-08-29 |
遗传研究所有限公司 |
磷脂酶抑制剂
|
|
US6500853B1
(en)
|
1998-02-28 |
2002-12-31 |
Genetics Institute, Llc |
Inhibitors of phospholipase enzymes
|
|
DE60024785T2
(de)
*
|
1999-02-22 |
2006-09-14 |
Amorepacific Corp. |
Vanilloid-analoge die resiniferatoxin-pharmacophore enthalten als wirksame vanilloid rezeptor agonisten und analgetika, zusammensetzungen und ihre verwendung
|
|
GB9920912D0
(en)
|
1999-09-03 |
1999-11-10 |
Indena Spa |
Novel derivatives of flavones,xanthones and coumarins
|
|
AU4742101A
(en)
|
2000-03-17 |
2001-10-03 |
Merck & Co., Inc. |
Antagonists of gonadotropin releasing hormone
|
|
JP2004525071A
(ja)
|
2000-07-20 |
2004-08-19 |
ニューロジェン コーポレイション |
カプサイシン受容体リガンド
|
|
CA2417507A1
(en)
*
|
2000-08-21 |
2002-02-28 |
Pacific Corporation |
Novel thiourea derivatives and the pharmaceutical compositions containing the same
|
|
FR2815033B1
(fr)
|
2000-10-06 |
2003-09-05 |
Negma Lab |
Derives de 7-carboxy-flavones, porcede pour leur preparation et leur application en therapeutique
|
|
NZ526622A
(en)
|
2000-12-11 |
2006-07-28 |
Amgen Sf Llc |
CXCR3 antagonists
|
|
JP4205430B2
(ja)
|
2001-03-26 |
2009-01-07 |
ノバルティス アクチエンゲゼルシャフト |
疼痛を治療するための、バニロイド受容体アンタゴニストとして、使用するための縮合ピリジン誘導体
|
|
AU2002325381A1
(en)
|
2001-07-31 |
2003-02-24 |
Bayer Healthcare Ag |
Naphthylurea and naphthylacetamide derivatives as vanilloid receptor 1 (vr1) antagonists
|
|
GB0128499D0
(en)
|
2001-11-28 |
2002-01-23 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
IL147416A
(en)
*
|
2001-12-31 |
2008-11-26 |
Israel State |
Combined modalities for improved cancer treatment
|
|
US7074805B2
(en)
*
|
2002-02-20 |
2006-07-11 |
Abbott Laboratories |
Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor
|
|
US7381730B2
(en)
|
2002-03-15 |
2008-06-03 |
Bristol-Myers Squibb Company |
3-arylquinazoline derivatives as selective estrogen receptor beta modulators
|
|
AU2003238157A1
(en)
†
|
2002-06-18 |
2003-12-31 |
Sankyo Company, Limited |
Fused-ring pyrimidin-4(3h)-one derivatives, processes for the preparation and uses thereof
|
|
CN1665791A
(zh)
|
2002-07-05 |
2005-09-07 |
霍夫曼-拉罗奇有限公司 |
喹唑啉衍生物
|
|
EP1398032A1
(en)
|
2002-09-10 |
2004-03-17 |
PheneX Pharmaceuticals AG |
4-Oxo-quinazolines as LXR nuclear receptor binding compounds
|
|
GB0223730D0
(en)
|
2002-10-11 |
2002-11-20 |
Novartis Ag |
Organic compounds
|
|
US20060052345A1
(en)
|
2002-11-04 |
2006-03-09 |
Nps Pharmaceuticals, Inc. |
Quinazolinone compounds as calcilytics
|
|
EP1611112B1
(en)
|
2003-02-11 |
2012-08-22 |
Vernalis (Cambridge) Limited |
Isoxazole compounds as inhibitors of heat shock proteins
|
|
US20060089353A1
(en)
|
2003-03-06 |
2006-04-27 |
Maki Iwahashi |
Indole derivative compounds and drugs containing the compounds as the active ingredient
|
|
JP2006193426A
(ja)
|
2003-09-05 |
2006-07-27 |
Sankyo Co Ltd |
置換された縮環ピリミジン−４（３ｈ）−オン化合物
|
|
WO2005040112A1
(en)
|
2003-10-14 |
2005-05-06 |
Oxagen Limited |
Compounds with pgd2 antagonist activity
|
|
AU2004290626A1
(en)
|
2003-11-14 |
2005-06-02 |
Merck Sharp & Dohme Limited |
Bicyclic pyrimidin-4-(3H)-ones and analogues and derivatives thereof which modulate the function of the vanilloid-1 receptor (VR1)
|
|
BRPI0507629A
(pt)
|
2004-02-13 |
2007-07-03 |
Banyu Pharma Co Ltd |
composto, antagonista do receptor e agonista inverso do receptor da histamina h3, agente profilático ou terapêutico para uma doença metabólica, uma doença circulatória ou uma doença do sistema nervoso, ou um seu sal farmaceuticamente aceitável
|
|
GB0412768D0
(en)
|
2004-06-08 |
2004-07-07 |
Novartis Ag |
Organic compounds
|
|
GB0412769D0
(en)
|
2004-06-08 |
2004-07-07 |
Novartis Ag |
Organic compounds
|
|
CA2607929A1
(en)
|
2005-05-11 |
2006-11-16 |
Merck Sharp & Dohme Limited |
2,3-substituted fused bicyclic pyrimidin-4(3h)-ones modulating the function of the vanilloid-1 receptor (vr1)
|
|
GB0525068D0
(en)
|
2005-12-08 |
2006-01-18 |
Novartis Ag |
Organic compounds
|
|
WO2009010529A1
(en)
|
2007-07-18 |
2009-01-22 |
Novartis Ag |
Synergistic combinations of vr-1 antagonists and cox-2 inhibitors
|
|
US8349852B2
(en)
|
2009-01-13 |
2013-01-08 |
Novartis Ag |
Quinazolinone derivatives useful as vanilloid antagonists
|