JP2010537639A5 - - Google Patents
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- JP2010537639A5 JP2010537639A5 JP2010523120A JP2010523120A JP2010537639A5 JP 2010537639 A5 JP2010537639 A5 JP 2010537639A5 JP 2010523120 A JP2010523120 A JP 2010523120A JP 2010523120 A JP2010523120 A JP 2010523120A JP 2010537639 A5 JP2010537639 A5 JP 2010537639A5
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- double
- antisense strand
- rna molecule
- strand
- nucleotides
- Prior art date
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96825707P | 2007-08-27 | 2007-08-27 | |
| US2975308P | 2008-02-19 | 2008-02-19 | |
| US3895408P | 2008-03-24 | 2008-03-24 | |
| PCT/US2008/074528 WO2009029688A2 (en) | 2007-08-27 | 2008-08-27 | Compositions of asymmetric interfering rna and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014032700A Division JP5986596B2 (ja) | 2007-08-27 | 2014-02-24 | 非対称性干渉rnaの組成物およびその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010537639A JP2010537639A (ja) | 2010-12-09 |
| JP2010537639A5 true JP2010537639A5 (enExample) | 2013-01-24 |
Family
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Family Applications (7)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010523120A Pending JP2010537639A (ja) | 2007-08-27 | 2008-08-27 | 非対称性干渉rnaの組成物およびその使用 |
| JP2010523121A Pending JP2010537640A (ja) | 2007-08-27 | 2008-08-27 | マイクロrna模倣剤または阻害剤としての非対称性rna二重鎖の組成物 |
| JP2014032700A Active JP5986596B2 (ja) | 2007-08-27 | 2014-02-24 | 非対称性干渉rnaの組成物およびその使用 |
| JP2015085681A Pending JP2015130885A (ja) | 2007-08-27 | 2015-04-20 | 非対称性干渉rnaの組成物およびその使用 |
| JP2016113256A Active JP6236498B2 (ja) | 2007-08-27 | 2016-06-07 | 非対称性干渉rnaの組成物およびその使用 |
| JP2016122512A Active JP6453275B2 (ja) | 2007-08-27 | 2016-06-21 | 非対称性干渉rnaの組成物およびその使用 |
| JP2017091309A Pending JP2017127333A (ja) | 2007-08-27 | 2017-05-01 | 非対称性干渉rnaの組成物およびその使用 |
Family Applications After (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010523121A Pending JP2010537640A (ja) | 2007-08-27 | 2008-08-27 | マイクロrna模倣剤または阻害剤としての非対称性rna二重鎖の組成物 |
| JP2014032700A Active JP5986596B2 (ja) | 2007-08-27 | 2014-02-24 | 非対称性干渉rnaの組成物およびその使用 |
| JP2015085681A Pending JP2015130885A (ja) | 2007-08-27 | 2015-04-20 | 非対称性干渉rnaの組成物およびその使用 |
| JP2016113256A Active JP6236498B2 (ja) | 2007-08-27 | 2016-06-07 | 非対称性干渉rnaの組成物およびその使用 |
| JP2016122512A Active JP6453275B2 (ja) | 2007-08-27 | 2016-06-21 | 非対称性干渉rnaの組成物およびその使用 |
| JP2017091309A Pending JP2017127333A (ja) | 2007-08-27 | 2017-05-01 | 非対称性干渉rnaの組成物およびその使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (6) | US9328345B2 (enExample) |
| EP (4) | EP3121281B1 (enExample) |
| JP (7) | JP2010537639A (enExample) |
| CN (3) | CN105018492B (enExample) |
| CA (2) | CA2735166C (enExample) |
| DK (1) | DK2193140T3 (enExample) |
| ES (2) | ES2617877T3 (enExample) |
| WO (2) | WO2009029688A2 (enExample) |
Families Citing this family (148)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008073578A2 (en) | 2006-12-08 | 2008-06-19 | Iowa State University Research Foundation, Inc. | Plant genes involved in nitrate uptake and metabolism |
| EP3121281B1 (en) | 2007-08-27 | 2021-03-31 | 1Globe Health Institute LLC | Compositions of asymmetric interfering rna and uses thereof |
| US8097712B2 (en) | 2007-11-07 | 2012-01-17 | Beelogics Inc. | Compositions for conferring tolerance to viral disease in social insects, and the use thereof |
| KR100949791B1 (ko) * | 2007-12-18 | 2010-03-30 | 이동기 | 오프-타겟 효과를 최소화하고 RNAi 기구를 포화시키지않는 신규한 siRNA 구조 및 그 용도 |
| EP2342340A1 (en) | 2008-09-22 | 2011-07-13 | Rxi Pharmaceuticals Corporation | Rna interference in skin indications |
| US20110287026A1 (en) | 2008-09-23 | 2011-11-24 | President And Fellows Of Harvard College | Sirt4 and uses thereof |
| WO2010045384A2 (en) | 2008-10-15 | 2010-04-22 | Somagenics Inc. | Short hairpin rnas for inhibition of gene expression |
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| CN118460650B (zh) * | 2024-07-10 | 2025-02-14 | 凯莱英医药集团(天津)股份有限公司 | 一种Nedosiran的制备方法 |
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| US20060211642A1 (en) * | 2001-05-18 | 2006-09-21 | Sirna Therapeutics, Inc. | RNA inteference mediated inhibition of hepatitis C virus (HVC) gene expression using short interfering nucleic acid (siNA) |
| US7074824B2 (en) | 2001-07-31 | 2006-07-11 | Arqule, Inc. | Pharmaceutical compositions containing beta-lapachone, or derivatives or analogs thereof, and methods of using same |
| US6962944B2 (en) | 2001-07-31 | 2005-11-08 | Arqule, Inc. | Pharmaceutical compositions containing beta-lapachone, or derivatives or analogs thereof, and methods of using same |
| EP2305813A3 (en) * | 2002-11-14 | 2012-03-28 | Dharmacon, Inc. | Fuctional and hyperfunctional sirna |
| US20040248299A1 (en) * | 2002-12-27 | 2004-12-09 | Sumedha Jayasena | RNA interference |
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| US20060069050A1 (en) * | 2004-02-17 | 2006-03-30 | University Of Massachusetts | Methods and compositions for mediating gene silencing |
| US20050203047A1 (en) * | 2004-03-10 | 2005-09-15 | Ulrich Thomann | Delivery vectors for short interfering RNA, micro-RNA and antisense RNA |
| CA2559955C (en) * | 2004-03-15 | 2016-02-16 | City Of Hope | Methods and compositions for the specific inhibition of gene expression by double-stranded rna |
| US20060142228A1 (en) | 2004-12-23 | 2006-06-29 | Ambion, Inc. | Methods and compositions concerning siRNA's as mediators of RNA interference |
| EP3121281B1 (en) | 2007-08-27 | 2021-03-31 | 1Globe Health Institute LLC | Compositions of asymmetric interfering rna and uses thereof |
| KR100949791B1 (ko) * | 2007-12-18 | 2010-03-30 | 이동기 | 오프-타겟 효과를 최소화하고 RNAi 기구를 포화시키지않는 신규한 siRNA 구조 및 그 용도 |
| TW201620525A (zh) | 2014-03-14 | 2016-06-16 | 波士頓生醫公司 | 使k-ras靜默之非對稱干擾rna組成物及其使用方法 |
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